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PLATELETS (THROMBOCYTES) Lecture by GK Mbassa
Purpose of knowing structure, biochemistry and functions of platelets   ,[object Object],[object Object]
[object Object]
Morphology of platelets ,[object Object],[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object]
[object Object],[object Object]
[object Object]
[object Object],[object Object],[object Object]
[object Object]
Ultrastructural features of the platelet ,[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Functional organization of the platelet ,[object Object],[object Object],[object Object],[object Object],[object Object]
Peripheral zone ,[object Object],[object Object]
[object Object]
[object Object],[object Object]
[object Object],[object Object]
Sol-gel zone   ,[object Object],[object Object],[object Object]
[object Object],[object Object]
Organelle zone   ,[object Object]
[object Object]
[object Object],[object Object]
[object Object],[object Object]
External coat Microfilaments Alpha granule Open canalicular system Dense tubular system Microtubules Golgi complex Lysosome
[object Object],[object Object]
Membrane system   ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
Platelet constituents Platelet location  Constituent  Function  Exterior coat Fibrinogen Platelet aggregation Membrane  Arachidonic acid  Prostaglandin synthesis  Plaletet factor 3 (phospholipid)  Enhances Coagulation  cAMP  Inhibits release reaction
Platelet constituents Microtubules  Tubulin  Cytoskeleton  Contractility Microfilaments Thrombosthenin Shape change, clot reaction, release reaction  Alpha-granules  Beta-thromboglobulin  Impedes prostacylin production from endothelial cells  Catalase Enzymic process
Factor VIII-relatedantigen  Platelet adhesion to subendothelium  Fibrinogen  Shape change, clot reaction, release reaction  Beta-thromboglobulin Impedes prostacylin production from endothelial cells  Fibronectin  Adherence to extracellular matrix Promote wound healing

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Platelets (thrombocytes) correc

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  • 28. External coat Microfilaments Alpha granule Open canalicular system Dense tubular system Microtubules Golgi complex Lysosome
  • 29.
  • 30.
  • 31.
  • 32. Platelet constituents Platelet location Constituent Function Exterior coat Fibrinogen Platelet aggregation Membrane Arachidonic acid Prostaglandin synthesis Plaletet factor 3 (phospholipid) Enhances Coagulation cAMP Inhibits release reaction
  • 33. Platelet constituents Microtubules Tubulin Cytoskeleton Contractility Microfilaments Thrombosthenin Shape change, clot reaction, release reaction Alpha-granules Beta-thromboglobulin Impedes prostacylin production from endothelial cells Catalase Enzymic process
  • 34. Factor VIII-relatedantigen Platelet adhesion to subendothelium Fibrinogen Shape change, clot reaction, release reaction Beta-thromboglobulin Impedes prostacylin production from endothelial cells Fibronectin Adherence to extracellular matrix Promote wound healing