Class hypersensitivity

[object Object],[object Object],[object Object]

Allergies ,[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object]

Hypersensitivity ,[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],IgE antibodies produced in response to initial exposure to an allergen bind to receptors or mast cells. 1 On subsequent exposure to the same allergen, IgE molecules attached to a mast cell recog- nize and bind the allergen. 2 Degranulation of the cell, triggered by cross-linking of adjacent IgE molecules, releases histamine and other chemicals, leading to allergy symptoms. 3 1 2 3 Allergen IgE Histamine Granule Mast cell

[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

vascular permeability, sm contraction Bradykinin vasodilation, sm contraction, platelet activation Prostaglandins vascular permeability, sm contraction Leukotrienes Secondary mediators vascular permeability, sm contraction Serotonin Vascular permeability, sm contraction Histamine Primary mediators effects SOME SPACES molecule

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Clinical Signs of Localized Allergic Reactions

[object Object],[object Object],[object Object],[object Object],[object Object],Clinical Signs of Localized Allergic Reactions

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Clinical Signs of Systemic Allergic Reactions

Identifying HS-I: Allergy Testing ,[object Object],[object Object],[object Object]

Treatment for HS-I Disorders ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Treatment for HS-I Disorders ,[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Hypersensitivity Reactions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],ABO System and Transfusion Reactions

[object Object],[object Object],[object Object],[object Object],[object Object],Transfusion Reactions

[object Object],[object Object],[object Object],[object Object],Transfusion Reactions

ABO Blood Group Characteristics and Donor/Recipient Matches Table 18.2

[object Object],[object Object],[object Object],[object Object],[object Object],RH System and Hemolytic Disease of the Newborn

Hemolytic Disease of Newborn (HDN ) ,[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Type III (Immune-Complex Mediated) Hypersensitivity

Arthus Rx ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Localized Type III Hypersensitivity Reactions

[object Object],[object Object],[object Object],[object Object],[object Object],Type IV (Delayed or Cell-Mediated) Hypersensitivity

[object Object],[object Object],[object Object],[object Object],Tuberculin Response

[object Object],[object Object],[object Object],[object Object],[object Object],Tuberculin Response

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Allergic Contact Dermatitis

Class hypersensitivity

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Class hypersensitivity