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Depression and Aging
Welcome and Thank You

 Alone we can do so little,
together we can do so
much.
              ~ Helen Keller


                   Lynn Northrop, PhD
National Depression Screening Day
¨  1991 – 20 years next year!
¨  Initiated by Douglas Jacobs, MD, a Harvard

    psychiatrist
¨  Now run by SMH, Inc., a non-profit based outside of

    Boston which Jacobs heads
¨  Raises awareness about depression and depression
    treatment
¨  Screenings occur in every state in the US

¨  Screens more than a half million people per year

                         Lynn Northrop, PhD
What is Depression?
Major Depressive Episode* = symptoms for 2 weeks or more


     Depressed or irritable mood AND               Older adults
         at least 4 below:                         More likely to report
     ¨  Loss of interest or pleasure              physical symptoms
     ¨  Change in weight or appetite              Less likely to report mood
     ¨  Change in sleep                           symptoms
     ¨  Change in psychomotor activity            More likely to report
                                                   problems with memory
     ¨  Fatigue or low energy

     ¨  Worthlessness or guilt
                                                   Apathy and withdrawal
                                                   more common
     ¨  Cognitive dysfunction
                                                   Diminished self-worth is
     ¨  Recurrent thoughts of death
                                                   more prominent
     -  self or others (suicidal ideation)

     ¨  Interferes with functioning  Lynn Northrop, PhD
Mood Disorders
• Major Depressive Disorder
• Dysthymia

• Minor Depression

• Bipolar Disorders (I&II)

• Hypomania



                  Lynn Northrop, PhD
How common is major depression?
¨  21million people in US with Major Depressive
    Disorder
¨  Lifetime prevalence: 1 to 2 out of 10 people

¨  Older and younger adults have same risk

¨  More common in medically ill of any age

¨  Very common among caregivers (more than half)




                        Lynn Northrop, PhD
Lynn Northrop, PhD


Estimated number of depressed older adults


                 Number of      11% clinical
    Area
               people age 65+    depression

  California     3,866,140        42,5275

 SD County        325,615         35,818

  La Mesa         11,605           1,277

 City of San
                  128,008         14,080
    Diego
How does depression impact health?

¨  Depression is predictive of hip fracture (Mussolino, 2005), a
    second heart attack (Carney and Freedland, 2007), stroke
¨  Treating depression reduces arthritic pain (Lin, 2003)

¨  OA treated for their depression are 45% less likely
    to die in next 5 years (Univ. of Penn, 2007)
¨  Correlation with adherence and health behavior

¨  30,000 deaths by suicide in the US
          more than alzheimers, homicide, liver disease, arteriosclerosis, or HTN
          Suicide 50% higher in older adults


                                          Lynn Northrop, PhD
Additional Impact of depression
¨  Reduced Quality of Life
¨  Lost Productivity - $44 billion cost to employers
        Leading   cause of disability in US (NIMH)
¨  Lost, damaged relationships
¨  Less likely to take meds as prescribed, follow
    medical advice, etc.
¨  When all else is equal, depressed elders more
    likely to be placed in nursing home.

                                    Lynn Northrop, PhD
Who gets depressed?
¨  Anyone
¨  You, me, everyday people and famous people

¨  Rich, poor

¨  Male, female

¨  Young, old

¨  People of all races, religions, ethnicities,
    occupations, IQ s
¨  People across history




                        Lynn Northrop, PhD
Edwin "Buzz" Aldrin, astronaut                 Abraham Lincoln, U.S. President
Alexander the Great, king                      Greg Louganis, U.S. diver and Olympic gold medallist
Hans Christian Anderson, author                Robert McFarlane, former US Nat’l Security Adviser
Drew Barrymore, actress                        Marilyn Monroe, actor
Ludwig von Beethoven, composer                 Sir Isaac Newton, physicist
Marlon Brando, actor                           Florence Nightingale, British nurse
Dick Cavett, broadcaster                       Richard Nixon, U.S. president
Ray Charles, R&B performer                     Deborah Norville, television journalist
Winston Churchill, British prime minister      Dolly Parton, singer
Dick Clark, entertainer (American Bandstand)   Jimmie Piersall, baseball player
Calvin Coolidge, U.S. president                William Pitt, Prime Minister
Francis Ford Coppola, director                 Sylvia Plath, poet
Charles Darwin, explorer and scientist         Edgar Allen Poe, writer
Kitty Dukakis, former First Lady, Mass.        Jackson Pollock, artist
Thomas Edison, inventor                        Cole Porter, composer
Ralph Waldo Emerson, writer                    Yves Saint Laurent, fashion designer
Sigmund Freud, psychiatrist                    Charles Schulz, cartoonist (Peanuts)
Dwight Gooden, baseball player                 George Stephanopoulos, political advisor
Tipper Gore, wife of U.S. Vice-President       Darryl Strawberry, baseball player
Phil Graham, owner, Washington Post            Spencer Tracy, actor
Stephen Hawking, physicist                     Ted Turner, founder, CNN Network
Andrew Jackson, U.S. President                 Mark Twain, author
Thomas Jefferson, U.S. President               Vincent Van Gogh, artist
Larry King, talkshow host                      Walt Whitman, poet
Robert E. Lee, U.S. general                    Jonathan Winters, comedian
John Lennon, musician                          Natalie Wood, actor
                                                                                   Lynn Northrop, PhD
Lots of older people get depressed…

                      Does that mean it’s
                 a normal part of aging?




                 Lynn Northrop, PhD
No.
 Depression is a treatable medical illness.
         No more common in older adults
                        than younger adults.
               It is not any more normal
                    than diabetes or cancer.
                    Lynn Northrop, PhD
Depression is a physical illness.
                   Lynn Northrop, PhD
How is depression treated

Antidepressant Medications

Therapy
  Individual,   group, IOP, inpatient

Medication + Therapy

ECT, TMS
                        Lynn Northrop, PhD
At the cellular level

Depression
affects
chemicals
that
enable
cells to
talk to
each
other.



                  Lynn Northrop, PhD
Glucose metabolism

Depressed
brains use
glucose
differently.
Change
thoughts,
change the
brain.



               Lynn Northrop, PhD
What puts people at risk for depression?

¨  Chronic medical problems
¨  Chronic pain

¨  Poverty

¨  Loss
                                       Are these
¨  Chronic Stressors                  CAUSES? (like
¨  Isolation
                                       heat causes burns
                                       or viruses cause
¨  Limited social support
                                       flu?)
¨  Family history

¨  Previous episode

¨  Some medications
                           Lynn Northrop, PhD
Lynn Northrop, PhD



Do situations cause depression?

       Alice and Georgia lived in the same
              senior housing complex.

Both 85 y.o., retired, recently widowed, live alone,
 very limited income, diabetes and heart disease,
chronic severe arthritic pain, one daughter -- lives
nearby, family and personal history of depression,

               And here s the kicker…

        Georgia was depressed. Alice was not.
Cognitive-Behavioral Model of Depression

¨  Depressed people are more likely to think
    inaccurate thoughts and to believe them.
¨  Depressed people are more likely to behave in

    ways that maintain depression.
¨  Treatment targets thoughts and behaviors.




                         Lynn Northrop, PhD
Common Inaccurate Thoughts
¨  All-or-nothing
¨  Negative filter (on self and others)

¨  Catastrophic

¨  Mind-reading

¨  Taking it personal

¨  Should statements




                           Lynn Northrop, PhD
Common changes in behavior
¨  Dropping hobbies
¨  Spending more time alone

¨  Sit more

¨  More time in bed

¨  Complain/criticize more

¨  Dismiss compliments

¨  Procrastinate

¨  Less self-care


                        Lynn Northrop, PhD
Lynn Northrop, PhD


Cognitive Behavioral Model of Depression



                          Thoughts




        Behaviors                           Feelings




       Focused on the here and now more than history
Downward Spiral

         Feel Bad                         Feel Even
                                            Better

         Do Less                            Do More


        Feel Worse                        Feel a Little
                                            Better

         Do Even                            Do
           Less                           Something


                     Lynn Northrop, PhD
Staying well…
¨  Stay active               At Gary and Mary West Senior
                              Wellness Center:
¨  Keep connected            • Feeling fit
                              • Yoga
¨  Daily APES                • Tai chi
                              • Travel class
¨  Strive for accurate       • Movies
    thinking (not always +)   • Cooking class
                              • Book club
¨  Look for the good         • Civic engagement/volunteerism
                              • Games
¨  Live in the moment        • Health education
                              • Sing-along
¨  Complain/criticize less   • Bingo
                              • Stress and happiness
¨  Express gratitude         management class
                              • SCREENINGS
    every day                 • And more!             Lynn Northrop, PhD
Take Home Messages
¨  Depression is fairly common, but not normal
¨  Depression is a medical illness, not weakness, not

      crazy
¨  Depression leads to many adverse consequences

    (social, medical, can be fatal)
¨  Depression is very treatable

¨  Help is available

¨  If you or a loved on is depressed, get help




                            Lynn Northrop, PhD

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Depression And Aging.National Depression Screening Day.Northrop

  • 2. Welcome and Thank You Alone we can do so little, together we can do so much. ~ Helen Keller Lynn Northrop, PhD
  • 3. National Depression Screening Day ¨  1991 – 20 years next year! ¨  Initiated by Douglas Jacobs, MD, a Harvard psychiatrist ¨  Now run by SMH, Inc., a non-profit based outside of Boston which Jacobs heads ¨  Raises awareness about depression and depression treatment ¨  Screenings occur in every state in the US ¨  Screens more than a half million people per year Lynn Northrop, PhD
  • 4. What is Depression? Major Depressive Episode* = symptoms for 2 weeks or more Depressed or irritable mood AND Older adults at least 4 below: More likely to report ¨  Loss of interest or pleasure physical symptoms ¨  Change in weight or appetite Less likely to report mood ¨  Change in sleep symptoms ¨  Change in psychomotor activity More likely to report problems with memory ¨  Fatigue or low energy ¨  Worthlessness or guilt Apathy and withdrawal more common ¨  Cognitive dysfunction Diminished self-worth is ¨  Recurrent thoughts of death more prominent -  self or others (suicidal ideation) ¨  Interferes with functioning Lynn Northrop, PhD
  • 5. Mood Disorders • Major Depressive Disorder • Dysthymia • Minor Depression • Bipolar Disorders (I&II) • Hypomania Lynn Northrop, PhD
  • 6. How common is major depression? ¨  21million people in US with Major Depressive Disorder ¨  Lifetime prevalence: 1 to 2 out of 10 people ¨  Older and younger adults have same risk ¨  More common in medically ill of any age ¨  Very common among caregivers (more than half) Lynn Northrop, PhD
  • 7. Lynn Northrop, PhD Estimated number of depressed older adults Number of 11% clinical Area people age 65+ depression California 3,866,140 42,5275 SD County 325,615 35,818 La Mesa 11,605 1,277 City of San 128,008 14,080 Diego
  • 8. How does depression impact health? ¨  Depression is predictive of hip fracture (Mussolino, 2005), a second heart attack (Carney and Freedland, 2007), stroke ¨  Treating depression reduces arthritic pain (Lin, 2003) ¨  OA treated for their depression are 45% less likely to die in next 5 years (Univ. of Penn, 2007) ¨  Correlation with adherence and health behavior ¨  30,000 deaths by suicide in the US   more than alzheimers, homicide, liver disease, arteriosclerosis, or HTN   Suicide 50% higher in older adults Lynn Northrop, PhD
  • 9. Additional Impact of depression ¨  Reduced Quality of Life ¨  Lost Productivity - $44 billion cost to employers   Leading cause of disability in US (NIMH) ¨  Lost, damaged relationships ¨  Less likely to take meds as prescribed, follow medical advice, etc. ¨  When all else is equal, depressed elders more likely to be placed in nursing home. Lynn Northrop, PhD
  • 10. Who gets depressed? ¨  Anyone ¨  You, me, everyday people and famous people ¨  Rich, poor ¨  Male, female ¨  Young, old ¨  People of all races, religions, ethnicities, occupations, IQ s ¨  People across history Lynn Northrop, PhD
  • 11. Edwin "Buzz" Aldrin, astronaut Abraham Lincoln, U.S. President Alexander the Great, king Greg Louganis, U.S. diver and Olympic gold medallist Hans Christian Anderson, author Robert McFarlane, former US Nat’l Security Adviser Drew Barrymore, actress Marilyn Monroe, actor Ludwig von Beethoven, composer Sir Isaac Newton, physicist Marlon Brando, actor Florence Nightingale, British nurse Dick Cavett, broadcaster Richard Nixon, U.S. president Ray Charles, R&B performer Deborah Norville, television journalist Winston Churchill, British prime minister Dolly Parton, singer Dick Clark, entertainer (American Bandstand) Jimmie Piersall, baseball player Calvin Coolidge, U.S. president William Pitt, Prime Minister Francis Ford Coppola, director Sylvia Plath, poet Charles Darwin, explorer and scientist Edgar Allen Poe, writer Kitty Dukakis, former First Lady, Mass. Jackson Pollock, artist Thomas Edison, inventor Cole Porter, composer Ralph Waldo Emerson, writer Yves Saint Laurent, fashion designer Sigmund Freud, psychiatrist Charles Schulz, cartoonist (Peanuts) Dwight Gooden, baseball player George Stephanopoulos, political advisor Tipper Gore, wife of U.S. Vice-President Darryl Strawberry, baseball player Phil Graham, owner, Washington Post Spencer Tracy, actor Stephen Hawking, physicist Ted Turner, founder, CNN Network Andrew Jackson, U.S. President Mark Twain, author Thomas Jefferson, U.S. President Vincent Van Gogh, artist Larry King, talkshow host Walt Whitman, poet Robert E. Lee, U.S. general Jonathan Winters, comedian John Lennon, musician Natalie Wood, actor Lynn Northrop, PhD
  • 12. Lots of older people get depressed… Does that mean it’s a normal part of aging? Lynn Northrop, PhD
  • 13. No. Depression is a treatable medical illness. No more common in older adults than younger adults. It is not any more normal than diabetes or cancer. Lynn Northrop, PhD
  • 14. Depression is a physical illness. Lynn Northrop, PhD
  • 15. How is depression treated Antidepressant Medications Therapy  Individual, group, IOP, inpatient Medication + Therapy ECT, TMS Lynn Northrop, PhD
  • 16. At the cellular level Depression affects chemicals that enable cells to talk to each other. Lynn Northrop, PhD
  • 18. What puts people at risk for depression? ¨  Chronic medical problems ¨  Chronic pain ¨  Poverty ¨  Loss Are these ¨  Chronic Stressors CAUSES? (like ¨  Isolation heat causes burns or viruses cause ¨  Limited social support flu?) ¨  Family history ¨  Previous episode ¨  Some medications Lynn Northrop, PhD
  • 19. Lynn Northrop, PhD Do situations cause depression? Alice and Georgia lived in the same senior housing complex. Both 85 y.o., retired, recently widowed, live alone, very limited income, diabetes and heart disease, chronic severe arthritic pain, one daughter -- lives nearby, family and personal history of depression, And here s the kicker… Georgia was depressed. Alice was not.
  • 20. Cognitive-Behavioral Model of Depression ¨  Depressed people are more likely to think inaccurate thoughts and to believe them. ¨  Depressed people are more likely to behave in ways that maintain depression. ¨  Treatment targets thoughts and behaviors. Lynn Northrop, PhD
  • 21. Common Inaccurate Thoughts ¨  All-or-nothing ¨  Negative filter (on self and others) ¨  Catastrophic ¨  Mind-reading ¨  Taking it personal ¨  Should statements Lynn Northrop, PhD
  • 22. Common changes in behavior ¨  Dropping hobbies ¨  Spending more time alone ¨  Sit more ¨  More time in bed ¨  Complain/criticize more ¨  Dismiss compliments ¨  Procrastinate ¨  Less self-care Lynn Northrop, PhD
  • 23. Lynn Northrop, PhD Cognitive Behavioral Model of Depression Thoughts Behaviors Feelings Focused on the here and now more than history
  • 24. Downward Spiral Feel Bad Feel Even Better Do Less Do More Feel Worse Feel a Little Better Do Even Do Less Something Lynn Northrop, PhD
  • 25. Staying well… ¨  Stay active At Gary and Mary West Senior Wellness Center: ¨  Keep connected • Feeling fit • Yoga ¨  Daily APES • Tai chi • Travel class ¨  Strive for accurate • Movies thinking (not always +) • Cooking class • Book club ¨  Look for the good • Civic engagement/volunteerism • Games ¨  Live in the moment • Health education • Sing-along ¨  Complain/criticize less • Bingo • Stress and happiness ¨  Express gratitude management class • SCREENINGS every day • And more! Lynn Northrop, PhD
  • 26. Take Home Messages ¨  Depression is fairly common, but not normal ¨  Depression is a medical illness, not weakness, not crazy ¨  Depression leads to many adverse consequences (social, medical, can be fatal) ¨  Depression is very treatable ¨  Help is available ¨  If you or a loved on is depressed, get help Lynn Northrop, PhD