Klinis pasien ALL.pptx

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L

ALL

Saúde e medicina

• Pansitopenia (Hb :10.2; AL : 1.0; AT : 12)
• Anemia mikrositik normokromik
• Limfositosis relatif (83.7%)
• Ditemukan hepatosplenomegali
• Ditemukan sel blast pada apusan darah tepi (blast like 12%)
• Ditemukan normoblastik dan polikromasi
• BMP : gambaran blood tap, ditemukan limfoblast 3%
• Retikulosit menurun

Diagnosis Banding Pansitopenia
• Hematopoietic stem cell injury : Anemia aplastic
• Hematopoietic mutasi clonal : MDS, Leukemia, PNH
• Myelophtishic (bone marrow infiltration) : Granulomatous disease TB,
limfoma, metastase cancer, myelofibrosis
• Maturation defect : Anemia megaloblastic
• Enhanced periferal destruction : Hipersplenisme, Autoimmune
disease (SLE), HLH (Hemophagocytosis Lymphohistiocytosis)

Macrophage Activation Syndrome: A Report of Two Cases and a
Literature Review
Asaad Alkoht,Ibrahem Hanafi,and Basheer Khalil.

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Klinis pasien ALL.pptx

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2. • Pansitopenia (Hb :10.2; AL : 1.0; AT : 12) • Anemia mikrositik normokromik • Limfositosis relatif (83.7%) • Ditemukan hepatosplenomegali • Ditemukan sel blast pada apusan darah tepi (blast like 12%) • Ditemukan normoblastik dan polikromasi • BMP : gambaran blood tap, ditemukan limfoblast 3% • Retikulosit menurun

3. Diagnosis Banding Pansitopenia • Hematopoietic stem cell injury : Anemia aplastic • Hematopoietic mutasi clonal : MDS, Leukemia, PNH • Myelophtishic (bone marrow infiltration) : Granulomatous disease TB, limfoma, metastase cancer, myelofibrosis • Maturation defect : Anemia megaloblastic • Enhanced periferal destruction : Hipersplenisme, Autoimmune disease (SLE), HLH (Hemophagocytosis Lymphohistiocytosis)

4. Macrophage Activation Syndrome: A Report of Two Cases and a Literature Review Asaad Alkoht,Ibrahem Hanafi,and Basheer Khalil.