Laurence Dawkins-Hall

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I have an HCPC accredited Bio medical sciences degree (1987). I have 15 years experience of molecular/cell biology and protein biochemistry and 10 years experience of genetics and genomics, including transcriptomics & genome laboratories in the USA. I possess 5 years drug discovery experience. I have 40 publications, comprising peer reviewed publications, conference papers & text book materials culminating in 350 citations . I participated in a project which was the first to describe and make formal submissions to Gen Bank regarding a murine Cadherin (DCS-2), cf. #L33779 I am a review Editor for Frontiers Microbiology, infectious diseases I have standard DNA, RNA & protein techniques...

compound library screens recombinant protein expression assay development extended gene expression networks micro arrays parasitology radio ligand assay drug discovery drug ligand modelling dna sequencing core facilities trypanosomiasis genomics enzyme kinetics rna editing in silico modelling cycle sequencing abrf bacs automated dna sequencing dsrg genetics infectious diseases qtl's microbial therapeutics transcriptomics exome sequencing rt pcr snp detection parasitology drug discovery

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Lab talk 060809 radioligand assay to validate in slico predicted rel inhibitors_progress report #1_principles and initial screen

Há 7 anos • 40 Visualizações

Lab talk 180909 radioligand assay to validate in silico predicted rel1 inhibitors progress report #2_identification of initial hits

Há 7 anos • 37 Visualizações

Lab talk 201109 radioligand assay for validating in slico predicted rel1 antagonists_progress #3_titration of initial hits

Há 7 anos • 37 Visualizações

Lab talk 181209 radioligand assay for validating in silico rel 1 antagonist hits_progress report #4_further hit titrations

Há 7 anos • 51 Visualizações

06 isafg p77 genome wide expression consequences of a disease resistance qtl are strongly influenced by genetic background oral presentation

Há 7 anos • 64 Visualizações

Abstract bookfinal-3 bsp 2012 glasgow

Há 7 anos • 593 Visualizações

RNA editing as a drug target development of a high through put fluorescent assay to identify inhibitors of rel 1 micro therapy 2011

Há 7 anos • 26 Visualizações

RNA editing as a drug target in tryp. development of a high throughput fluorescent assay microbial therapeutics glasgow 2011

Há 7 anos • 23 Visualizações

Rna editing as a drug target identification of inhibitors of rel 1 bsp 210

Há 7 anos • 32 Visualizações

Rna editing as a drug target identification of inhibitors of rel 1 bsp 2010

Há 7 anos • 30 Visualizações

RNA editing as a drug target in tryp. development of a high throughput sceening assay to identify inhibitors of rel 1 sulsa 2012

Há 7 anos • 56 Visualizações

Laurence Dawkins-Hall

Apresentações

Genomic analysis of a hypertensive qtl on rat chr 1

Lab talk 020710 comparing bac r_rel 1 with e coli rrel 1 for use in fret assay

Lab talk 190210 efficacy studies on radioligand hits_beginnings of fret assay_principles_induction of rel 1

Lab talk 020410 inducing rel 1 to set up ht fret assay_progress

Lab talk 070510 inducing r_rel1 for establishing fret assay_ic50 studies with mordant black

Lab talk 300710 optimisation of fret assay parameters_calculating km of atp substrate_den regimen

Labtalk 151010 optimising fret assay_ligation buffer_[atp]_fluorophores

Labtalk 101210 optimising fret assay_den_optimising r_rel 1 production_heat shock

Lab talk 060809 radioligand assay to validate in slico predicted rel inhibitors_progress report #1_principles and initial screen

Lab talk 180909 radioligand assay to validate in silico predicted rel1 inhibitors progress report #2_identification of initial hits

Lab talk 201109 radioligand assay for validating in slico predicted rel1 antagonists_progress #3_titration of initial hits

Lab talk 181209 radioligand assay for validating in silico rel 1 antagonist hits_progress report #4_further hit titrations

06 isafg p77 genome wide expression consequences of a disease resistance qtl are strongly influenced by genetic background oral presentation

Documentos

Abstract bookfinal-3 bsp 2012 glasgow

RNA editing as a drug target development of a high through put fluorescent assay to identify inhibitors of rel 1 micro therapy 2011

RNA editing as a drug target in tryp. development of a high throughput fluorescent assay microbial therapeutics glasgow 2011

Rna editing as a drug target identification of inhibitors of rel 1 bsp 210

Rna editing as a drug target identification of inhibitors of rel 1 bsp 2010

RNA editing as a drug target in tryp. development of a high throughput sceening assay to identify inhibitors of rel 1 sulsa 2012

RNA editing as a drug target in tryp assay dev woods_hole2_0411 acs v2

RNA editing as a drug target in tryp assay dev woodshole 2011

A systematic, data driven approach to the combined analysis of microarray and qtl data

Systemic analysis of data combined from genetic qtl's and gene expression data from micro arrays

Genome responses of trypanosome infected cattle

Genomic approaches to trypanosome resistance

An evaluation of methods used to sequence pGEM template within core facilities dsrg study

DSRG report 2001