LM CV Updated June 2016

CURRICULUM VITAE
Laszlo L. Mechtler, MD, FAAN
Dent Neurologic Institute
3890 Sheridan Drive
Amherst, New York 14226
(716) 510-3719 Fax: (716) 250-6039
lmechtler@dentinstitute.com
Roswell Park Cancer Institute
Department of Neuro-Oncology
Elm and Carlton Streets
Buffalo, New York 14263
Date of Birth: September 7, 1958 (Sydney, Australia)
(Updated May 2016)
Institution Location Graduation Degree
Buffalo State University of
New York
Buffalo, New York 1976-1977 Biochemistry
Semmelweis University
of Medicine
Budapest, Hungary 1978-1984 MD – cum laude
CERTIFICATIONS:
American Board of Neurology and Psychiatry, No. 32653; Issued: March 1990
UCNS Certification, Headache Medicine: Issued October, 2008, Certificate No. HM00405-08
UCNS Certification, Neuro-Oncology: Issued October, 2009, Certificate No. N00228-09
UCNS Certification, Neuroimaging: Issued September 30, 2008, Certificate No. N100224-08
NYS Certification, Medical Marijuana Certifier: Issued January 1, 2016
LICENSURE:
New York State Medical License, No. 171164; Issued: July 1987
Texas State Medical License, No. H5003: June 1988

Laszlo Mechtler, MD
Curriculum Vitae
Updated May 2016 acm 2
PRESENT POSITIONS:
Institution Position Dates
Millard Fillmore Hospitals
Buffalo, New York
Attending Neurologist
Director Dent Headache Clinic
Director Dent Imaging Center
1989 – Present
1998 – Present
2009 - Present
Buffalo, New York
Vice President/Medical Director
Director Brain Tumor Treatment Center
Chief of Neuro-Oncology
1999 – Present
1993 - Present
2002 - Present
MEDICAL TRAINING:
Millard Fillmore Hospital – Dept. of Medicine
Buffalo, New York
Intern 07/84 – 06/85
Millard Fillmore Hospital
Buffalo, New York
Resident, Neurology 07/85 – 06/87
State University of New York at Buffalo,
(SUNYAB) School of Medicine and
Biomedical Sciences
Buffalo, New York
Chief Resident, Neurology 07/87 – 06/88
University of Texas
M.D. Anderson Cancer Center
Houston, Texas
Neuro-oncology Fellow 07/88 – 12/88
University of Texas
M.D. Anderson Cancer Center
Houston, Texas
Neuro-Oncology Teaching Associate 01/89 – 06/89
Lucy Dent Imaging Center
Buffalo, New York
Neuroimaging Fellowship 01/90 – 01/91

Laszlo Mechtler, MD
Curriculum Vitae
MEMBERSHIPS:
American Medical Association
Intersocietal Commission for the Accreditation of Magnetic Resonance Laboratories, Inc.
Hungarian Medical Association of America
American Academy of Neurology
National Quality Forum Imaging Efficiency Steering Committee
American Society of Neuroimaging (President)
United Council for Neurologic Subspecialties
American College of Radiology (ACR) for the American Academy of Neurology
AAN Imaging Topic Work Group
European Association for Neuro-oncology
BRSNORG
RTOG Member
Society of Neuro-Oncology
American Headache Society
AWARDS AND DISTINCTIONS:
Student Research Grant in Biochemistry, Roswell Park Cancer Institute – 1979
Student Research Grant in Nuclear Medicine, Roswell Park Cancer Institute – 1981
Buffalo Ambassador – February, 1995
Clinical Instructor of the Year 2000 SUNYAB Neurology
Top 100 Docs, Buffalo Spree Magazine, Jan/Feb 2006
Outstanding Achievement Award from the Hungarian Government- Smoking Ban- August 2012
Top 100 Docs, Buffalo Spree Magazine, Jan 2015
APPOINTMENTS:
CLINICAL:
Buffalo, New York
Attending Neurologist and Neuro-Oncologist 07/89 – Present
Catholic Health System
Kenmore Mercy Hospital
South Buffalo Mercy
Buffalo, New York
Kaleida Health System
Buffalo General Hospital
Millard Fillmore Suburban Hospital
Buffalo, New York
Attending Neurologist
Attending Neurologic
07/89 – Present
Buffalo, New York
Director Brain Tumor Treatment
Center
1993 – Present

Laszlo Mechtler, MD
Curriculum Vitae
Buffalo, New York
Chief Neuro-Oncology
Department of Neurology
Professor of Neurology and Oncology, State
University New York at Buffalo, School of
Medicine and Biomedical Sciences
2000-Present
2007 – Present
ADMINISTRATIVE/ACADEMIC:
NATIONAL:
Picker International Inc.,
Cleveland Heights, Ohio
MRI Advisory Committee 1991 – 1992
American Society of Neuroimaging MRI Certification Committee 1992 – 1994
Hungarian Medical Association of America Fellowship Committee Chair 1992 – present
Hungarian Medical Association of America Member, Board of Directors 1992 – present
American Society of Neuroimaging MRI/CT Committee 1994 – 1995
Hungarian Medical Association of America Secretary 1994 – 2005
American Society of Neuroimaging Chair, Program Committee 1999 – 2000
American Society of Neuroimaging Director/ Faculty MRI Course 2000 – 2010
American Society of Neuroimaging Board of Directors 2002-2008
American Academy of Neurology Representative to the ICAMRL 2004-2006
Hungarian Medical Association of America President 2005-2010
American Society of Neuroimaging Journal of Neuroimaging Oversight
Committee
2005-2009
American Society of Neuroimaging Training & Fellowship Committee- Chair 2005-present
American Society of Neuroimaging Program Committee (Chair 2012-13) 2005-present
Intersocietal Commission for the Accreditation
of Magnetic Resonance Laboratories, Inc.
Board of Directors 2005 – 2007
National Institute of Neurology & Psychiatry
Budapest, Hungary
Director of Imaging and Research 2006 – present
United Council for Neurologic Subspecialties
American College of Radiology (ACR)
Delegate Representative for American
Academy of Neurology (AAN)
Neuro-Expert Panel
2005-present
2011 - present
American Society of Neuroimaging
Elected as a Fellow Member of the American
Academy of Neurology
Executive Committee for BrainPAC- (AAN)
Green Grass Advisors
President
FAAN Member
Executive Committee Member
Board of Directors- National
01/2013-2014
2015
2015-2017
2015- Present

Laszlo Mechtler, MD
Curriculum Vitae
State University of New York at Buffalo (SUNYAB)
Biomedical Sciences
Member, Radiosurgery Committee 1989-1992
Biomedical Sciences
Assistant Professor of Neurology
(GFT)
1989-1996
Biomedical Sciences
Professor of Clinical Neurology 1996-Present
(SUNYB) School of Medicine and Biomedical
Sciences
(SUNYB) School of Medicine and Biomedical
Sciences
Professor of Oncology at Roswell Park
Cancer Institute
Professor of Neurology and Oncology
2007–Present
2013- Present
PHARMACEUTICAL:
Advisory Board Member: Past National Speakers Bureau: Current National Speakers Bureau:
Schering-Plough Schering-Plough Depomed
GlaxoSmithKline GlaxoSmithKline Allergan
AstraZeneca AstraZeneca Teva
Merck Merck Pernix
Novartis Novaritis
Pharma Pharmacia
X-Cel Pfizer
UCB Pharma
Valeant
Ortho-McNeil
Supernus
Millard Fillmore Health System
Buffalo, New York
President, House Staff Association 1986 – 1988
Buffalo, New York
Member, Neuroimaging Research Group 1989 – Present

Laszlo Mechtler, MD
Curriculum Vitae
Buffalo, New York
Member, Neurology Nursing Liaison
Committee
1989 – 1996
Buffalo, New York
Member, Quality Assurance, Mortality
and Morbidity Review Committee
1989 – 1997
Buffalo, New York
Member, Quality Assurance, Mortality and
Morbidity Review Committee
1984-1995
Buffalo, New York
Member, Internal Review Board 1989 – 1995
Buffalo, New York
Member, Oncology Task Force 1994 – 1996
Buffalo, New York
Executive Council 1995 – Present
COMMUNITY SERVICE:
Brain Tumor Board
Moderator 1989 – Present
Buffalo – Rochester – Syracuse Neuro-
Oncology Group (BRSNOG)
Founding Member 1992
Buffalo – Rochester – Syracuse Neuro-
Oncology Group (BRSNOG)
Head, Oncology and Neuroimaging
Committee
1993–2000
Gorbachev Foundation for Children
Diplomat, Medical Fact Finding Mission,
Yugoslavia
1993
Gorbachev Foundation: First International
Concert for Pediatric AIDS
Health Consultant 1993
World University Games
Buffalo, New York
Chief Medical Officer 1993
Neuro-oncology Symposium
Buffalo Hilton Hotel
Buffalo, New York
Co-Chairman 1995
Hungarian Medical University Student
Exchange Program
Chair 1995 –Present
State University of New York at Buffalo
Center for Tomorrow
Organic Headaches
Moderator 1996
Roswell Park Cancer Institute and Hungarian
Medical University Student Exchange Program
President / Liaison 2008

Laszlo Mechtler, MD
Curriculum Vitae
Hungarian Medical Society of America
Symposium, Budapest, Hungary “Smoking
Cessation”
External Advisory Committee for Research
with Henry S. Friedman, MD for Training in
Neuro-Oncology
Chairman
Member
2008
2009 - Present
Appointment to Governor Cuomo’s
Medical Advisory Board of the State Athletic
Commission
Executive Committee for BrainPACS (AAN)
Member
Member
2012 – September
2014- Present
2015-Present
EDITORIAL BOARDS:
Journal Position Dates
Journal of Neuroimaging Ad-hoc reviewer 1994
Mayo Proceedings Ad-hoc reviewer 1995
Journal of Neuroimaging Editorial Board 1999 – present
Cancer Ad-hoc reviewer 2006 – present
Continuum Faculty / Contributing Editor 2007 – present
Neurology Clinics Guest Editor 2007 – present
Continuum
Continuum
Editorial Board
Associate Editor of Neuroimaging
2009-present
2014-present
BOOKS:
• Guest Editor, “Neuroimaging “ Neurologic Clinics, Vol 27 No. 1 Feb 2009
• Guest Editor/Chair, “Neuroimaging” Continuum- Life Long Learning in Neurology® with CD-ROM, Vol
14 No. 4 Aug 2008
• Guest Editor, “Neuroimaging” Neurologic Clinics, February 2014
• Guest Editor, “Neuroimaging” Continuum- Life Long Learning in Neurology®, 2016 Edition (In Progress)
PUBLICATIONS:
Book Chapters and Reviews
1. Mechtler LL and Kinkel PR. “Magnetic Resonance Imaging in Demyelinating, Infectious, Metabolic and
Congenital Diseases.” [Review] Current Opinion in Neurology 6 (6): 912-18, Dec 1993.
2. Mechtler LL and Cohen ME. “Clinical Presentation and Therapy of Spinal Tumors” Neurology in Clinical
Practice. Bradley WG, Daroff RB, Fenichel GM and Marsden CD editors. 1996.

Laszlo Mechtler, MD
Curriculum Vitae
3. Mechtler LL and Cohen ME. “Clinical Presentation and Therapy of Peripheral Nerve Tumors” Neurology
in Clinical Practice. Bradley WG, Daroff RB, Fenichel GM and Marsden CD editors. 1998.
4. Mechtler LL and Cohen ME. “Tumors of the Nervous System” Current Practice of Medicine. Koller WC
editor. 1998.
5. Mechtler LL. “Cancer Related Dementia” Neuroimaging of Normal Aging and Uncommon Causes of
Dementia. Fazekas F, Schmidt R. editors. 1999
6. Cohen ME, Mechtler, LL, Duffner P. “Thalamic, Hypothalamic and Optic Pathway Tumors.” Handbook
of Clinical Neurology. Vecht C. 1999.
7. Mechtler LL, Stiles Alan M. “Secondary Headaches.” Atlas of Migraine and Other Headaches 2004.
8. Mechtler LL. “Pain Syndromes Originating From the Base of the Skull”. Cancer pain: Pharmacologic,
Interventional and Palliative Approaches; Section 2: Chapter 5: 2006.
9. Evans RW, Rozen TD, Mechtler LL. “Neuroimaging and Other Diagnostic Testing in Headache”
Wolff’s Headache and Other Head Pain, 8th
Edition, September 2006.
10. Mechtler LL, Nandigam, K. “Spinal Cord Tumors: New Views and Future Directions”. Neurologic Clinics
2013 Feb;31(1): 241-68
11. Mechtler LL, Shastri K, Crutchfield K. “Advanced Neuroimaging of Mild Traumatic Brain Injury”
Neurologic Clinics 2014 Feb: 32(1): 31-58.
12. Mechtler LL, Nandigam K, Smirniotopoulos J. “Neuroimaging of Neurocutaneous Diseases”. Neurologic
Clinics 2014 Feb 32(1): 159-192.
13. Pinter N, Pfiffner T, Mechtler LL. “Neuroimaging of Spine Tumors”. Handbook of Clinical Neurology
2014.
14. Pfiffner T, Jani R, Mechtler LL. “Neuro-oncological Disorders of the Cerebellum”. Neurologic Clinics
2014.
15. Singh K, Pfiffner T, Mechtler, L. “Neuroimaging of Pain Syndromes due to Skull Based Tumors”. Current
Pain and Headache Reports. Springer. 2015
16. Singh, K, Mechtler, L, Klein, J. “Imaging of Spinal Cord Disorders”. Continuum. Lifelong Learning in
Neurology, AAN. 2016 (In Press)
17. Baig, M, Mechtler, L, Klein, J. “Neuroimaging in Neuro-Oncology”. Continuum. Lifelong Learning in
Neurology, AAN. 2016 (In Press)
REFERRED JOURNALS:
1. Gengo FM, Gabos C and Mechtler LL. “Quantitative Effects of Cetrizine and Dyphenhyrdramine on
Mental Performance Using an Automobile Driving Simulator.” Annals of Allergy 1990; 64 (6) 520.
2. Yung WK, Mechtler LL and Gleason MJ. “IV Carboplatin for Recurrent Malignant Glioma: A Phase II
Study.” Journal of Clinical Oncology May 1991.
3. Schmidt R, Mechtler LL, Kinkel PR, Fazekas F, Kinkel WR and Freidl W. “Cognitive Impairment After
Acute Supratentorial Stroke: A Six-Month Follow-Up Clinical and Computed Tomographic Study.”
European Arch Psychiatry Clin Neurosci 1993; 243: 11-15.

Laszlo Mechtler, MD
Curriculum Vitae
4. Capone PM, Mechtler LL, Bates VE, Kanna A and Kinkel PR. “Multiple Giant Intracranial Aneurysms
Associated With Lymphomatoid Granulomatosis: A Magnetic Resonance Imaging and Angiographic
Study.” Journal of Neuroimaging 1994 April; 4 (2): 109-111.
5. Bakshi R, Mechtler LL, Patel MJ, Gibbons KJ. “Spinal Leptomeningeal Hemangioblastomatosis in von
Hippel-Lindau Syndrome: Magnetic Resonance Imaging and Pathological Findings.” Journal of
Neuroimaging 1996; 6:67.
6. Bakshi R, Mechtler LL, Patel MJ, Lindsay BD, Messinger S, Gibbons KJ. “Spinal Leptomeningeal
Hemangioblastomatosis in von Hipple-Lindau Disease: MRI and Pathological Findings.” Journal of
Neuroimaging. 1997 Oct; 7(4):242-4.
7. Bakshi R, Kinkel PR, Mechtler LL, Bates VE. “Cerebral Ventricular Empyema Associated with Severe
Adult Pyogenic Meningitis: Computed Tomography Findings.” Clinical Neurology and Neurosurgery.
1997;99:252-255.
8. Bakshi R, Kinkel PR, Mechtler LL, Bates VE, Lindsay BD, Esposito SE, Kinkel WR. “Magnetic
Resonance Imaging Findings in 22 Cases of Myelitis: Comparison between Patients with and without
Multiple Sclerosis.” European Journal of Neurology 1998; 5:35-48.
9. Bakshi R, Bates VE, Mechtler LL, Kinkel PR, Kinkel WR. “Occipital lobe seizures as the major clinical
manifestation of reversible posterior leukoencephalopathy syndrome: Magnetic resonance imaging
findings”. Epilepsia 1998; 39:295-300.
10. Bakshi R, Kinkel PR, Mechtler LL, Bates VE, Kinkel WR. “Magnetic resonance imaging findings in acute
cerebellitis”. Clinical Imaging 1998; 22:79-85.
11. Bakshi R, Lindsay BD, Bates VE, Kinkel PR, Mechtler LL, Kinkel WR. “Cerebral venous infarctions
presenting as enhancing space-occupying lesions: Magnetic resonance imaging findings”. Journal of
Neuroimaging 1998; 8:210-215.
12. Bakshi R, Kinkel WR, Bates VE, Mechtler LL, Kinkel PR. “The cerebral intravascular enhancement sign
is a non-specific finding: A contrast-enhanced MRI study”. Neuroradiology 1999; 41:80-85.
13. Bakshi R, Wright PD, Kinkel PR, Bates VE, Mechtler LL, Kamran S, Pullicino PM, Sirotkin I, Kinkel
WR. “Cranial magnetic resonance imaging findings in bacterial endocarditis: the neuroimaging spectrum of
septic brain embolization demonstrated in twelve cases”. Journal of Neuroimaging 1999;9:78-84
14. Bakshi R, Kamran S, Kinkel PR, Bates VE, Mechtler LL, Janardhan V, Belani S, Kinkel WR. “Fluid-
attenuated inversion-recovery MR findings in acute and subacute cerebral intraventricular hemorrhage”.
AJNR: American Journal of Neuroradiology 1999;20:629–636
15. Ravichandran TP, Bakshi R, Heffner R, Mechtler LL, Gibbons KJ, Duarte DJ, Kinkel WR. “Giant
aggressive pituitary adenoma: Magnetic resonance imaging and pathological findings”. Journal of Neuro-
Oncology 1999 Jan; 41(1): 71-5
16. Bakshi R, Mechtler LL, Kamran S, Gosy E, Bates VE, Kinkel PR, Kinkel WR. “MRI findings in lumbar
puncture headache syndrome: abnormal dural meningeal and dural venous sinus enhancement”. Clinical
Imaging 1999 March-April; 23(2): 73-6
17. Bakshi R, Kamran S, Kinkel PR, Bates VE, Mechtler LL, Belani SL, Kinkel WR. “MRI findings in
cerebral intraventricular hemorrhages: analysis of 50 consecutive cases”. Neuroradiology 1999 June; 41(6)
401-9
18. Parmany, T., Mechtler, LL, “Differential regulation of MHC class II expression and NO release by B-
amyloid in rat astrocyte and microglia”. Brain Research 1999 Jul 24; 835(2) 213-23

Laszlo Mechtler, MD
Curriculum Vitae
19. Pazmany, T, Kosa, J, Mechtler, L, Tomasi, T. “Effect of transforming growth factor Beta I on microglial
MHC class 2 gene expression”. J Neuroimmunol. 2000 Mar 1; 103(2)122-30
20. Dubey N, Wasay M, Miletich RS, Mechtler LL, Bakshi R. “Utility of FDG-PET in the diagnosis of
Neurosarcoidosis” J Neurol Sci 2002 Dec 15; 205(1): 77-81
21. Korones DN, Benita-Weiss M, Coyle TE, Mechtler LL, Bushunow P, Evans B, Reardon DA, Quinn JA,
Friendman H. “Phase I Study of Temozolomide and Escalating Doses of Oral Etoposide for Adults with
Recurrent Malignant Glioma”. Cancer. 2003 Apr 15; 97(8): 1963-8
22. Blitshteyn S, Mechtler LL, Bakshi R. “Diffuse Dural Gadolinium MRI Enhancement Associated with
Bilateral Chronic Subdural Hematomas”. Clin Imaging. 2004 Mar-Apr; 28(2): 90-2
23. Mechtler LL, “Role of Neuroimaging in Our Understanding of the Pathogenesis of Primary Headaches”
Current Pain and Headache Reports 2004Oct; 8(5): 404-9
24. Tawk RG, Tan D, Mechtler LL, Fenstermaker RA. “Melanotic Schwannoma with Drop Metastases to the
Caudal Spine and High Expression of CD117”. J Neurooncol. 2005 Jan; 71(2): 151-6
25. Mechtler LL, “Neuroimaging of Headaches”, Continuum: Lifelong Learning in Neurology 2008 August,
Vol 14(4); 94-117
26. Mechtler LL, “Neuroimaging in Neuro-Oncology” and “Preface” , Neurology Clinics 2009 Feb; 27(1):
171-201
27. Tamoki DL, Tarnoki AD, Hyland A, Travers MJ, Dobson K, Mechtler L, Cummings KM. “Measurement
of Indoor Smoke Pollution in Public Places in Hungary”. Orv Hetil. 2010 Feb 7; 151(6):213-9. Hungarian.
28. Tarnoki DL, Tarnoki AD, Travers MJ, Mechtler L, Tamas L, Cummings KM. “Compliance Still a Problem
With No Smoking Law”. Tob Control. 2010 Dec; 19(6):520. Epub 2010 Sep 24.
29. DeLaPax RL, Wippold FJ II, Cornelius RS, Amin-Hanjani S, Angtuaco EJ, Broderick DF, Brown DC,
Creasy JL, Davis PC, Garvin CF, Hoh BL, McConnell CT Jr, Mechtler LL, Seidenwurm DJ,
Smirniotopoulos JG, Tobben PJ, Waxman Ad, Zipfel GJ. ”ACR Appropriateness Criteria®-
Cerebrovascular Disease”. J Am Coll Radiol. 2011 Aug; 8(8):532-8.
30. Seidenwurm DJ, Wippold FJ II, Cornelius RS, Angevine PD, Angtuaco EJ, Broderick DF, Brown DC,
Davis PC, Garvin CF, Hartl R, Holly L, McConnell CT Jr, Mechtler LL, Smirniotopoulos JF, Waxman
AD. “ACR Appropriateness Criteria®- Myelopathy”. J AM Coll Radiol. 2012 May; 9(5):315-24.
31. Farooq O, Lincoff NS, Saikali N, Prasad D, Miletich RS, Mechtler LL. “Novel Treatment for Radiation
Optic Neuropathy with Intravenous Bevacizumab”. J Neuroophthalmol. 2012 Dec; 32(4): 321-4
32. Crawley R, Wong E, Mechtler LL, Rodda B, O’Oconnor P. Steroid Sparing Effect of Corticorelin Acetate
(CrA) in Peritumoral Cerebral Edema is Associated with Improvement in Steroid Induced Myopathy.
Journal of Clinical Oncology 2012
33. Cornelius RS, Martin Jamie, Mechtler LL, et al. ACR Appropriateness Criteria®- ‘Sinonasal Disease’.
JACR 2013.
34. Fritz J, McVige J, Mechtler L. “Coding in Behavioral Neurology”. Continuum. April 2015.
35. Morr S, Qiu J, Prasad D, Mechtler LL, Fenstermaker RA: Radiologic Response to Radiation Therapy
Concurrent with Temozolomide for Progressive Simple Dysembryoplastic Neuroepithelial Tumor.
Accepted for publication in Acta Neurochir on May 3, 2016

Laszlo Mechtler, MD
Curriculum Vitae
36. Vilaas S. Shetty, Martin N. Reis, Mechtler L, et al. ACR Appropriateness Criteria®- ‘Head Trauma’ JACR
June 2016.
ABSTRACTS:
1. Mechtler LL, Withlam-Leitch S, Shin K, Kinkel WR. “MRI of the Cauda Equina in the Paraneoplastic
Anti-Hu Syndrome.” Journal of Neuro-Oncology, 21 (1) 7, 1994
2. Patel M, Truax B, Kinkel P, Shin K, Mechtler LL. “Neuroimaging of the Intravascular Malignant
Lymphomatosis Spine.” Journal of Neuro-Oncology, 21 (1) 7, 1994
3. Shin K, Mechtler LL, West C, Grand W. “Brain Tumor Assessment Index.” Journal of Neuro-
Oncology, 21 (1) 45, 1994
4. Shin K, Sibata C, West C, Mechtler LL, Grand W. “Thyroid Doses Due to Radiosurgery of the Brain.”
Journal of Neuro-Oncology, 21 (1) 45, 1994
5. Patrick JT, Mechtler LL, Budny J, Patel M, Heffner, R and Bates VE. “MRI in Granular Cell Tumor
(Choristoma) of the Neurophypophysis.” Journal of Neuroimaging, 5 (1) 62-63, 1995.
6. Patrick JT, Mechtler LL, Kinkel PR, Bates VE, Holmlund T and Kinkel WR. “Magnetic Resonance
Imaging Reveals T2 Shortening in the Motor Cortex and T2 Lengthening in the Subcortical White Matter
in Amyotrophic Lateral Sclerosis.” Journal of Neuroimaging, 5 (1) 61, 1995.
7. Bakshi, R., Mechtler, LL, Patel, M., Gibbons K. Spinal leptomeningeal hemangioblastomatosis in von
Hippel-Lindau syndrome: Magnetic imaging and pathological findings. J. Neuroimaging 6:67, 1996.
8. Bakshi R., Mechtler LL, Miletich R., Shin K., Gibbons, K. Radiation Optic Neuropathy: Correlation of
PET and MRI Findings. (Presented and published for 1996 annual meeting of the American Academy of
Neurology, San Francisco, CA) Neurology 1996: 46(supp 1): A245.
9. Prados M, Schold C, Fine H, Jaeckle K, Hochberg F, Mechtler LL, Fetell M, Phuphanich S, Feun L,
Janus T, Downing G, Ford K, Wortel C. Randomized Placebo Controlled Phase II Study of IV
Carboplatin With or Without IV RMP-7 in Patients With Recurrent Malignant Glioma. Presented at the
1998 ASCO Meeting in Los Angeles.
10. Bushnow T, Mechtler LL, Coyle T. Ida Rubicin in the Treatment of Recurrent Malignant Glioma.
ASCO, Los Angeles, 1998.
11. Cloughesy TR, Rich K, Moran C, Olsen J, Piepmeieer J, Mechtler LL, Fenstermaker R, Watson V,
Spenc A, Hochberg F, Dion J, Downing G, O’Toole T, Gobin P, Villablanca P, Black KL. A Multi-
Center Open Label, Single Arm Phase II Study of RMP-7 and Carboplatin Administered Intra-Arterially
(IA) for the Treatment of Malignant Glioma (MG). Presented at the 1998 ACO Meeting in Los Angeles.
12. Bakshi R, Wright PD, Kinkel PR, Bates VE, Metchler LL, Kamran S, Pullicino PM, Sirotkin I, Kinkel
WR. Cranial Magnetic Resonance Imaging Findings in Bacterial Endocarditis: The Neuroimaging
Spectrum of Septic Brain Embolization Demonstrated in Twelve Cases. Journal of Neuroimaging 1999;
9: 78-84
13. Shapiro WR, Mechtler LL, Cher L, Wheeler H, Hines V, Milsted R, O’Connor PC, Ryan RP, Recht L. A
Randomized, Double-Blind Study Comparing Corticorelin Acetate with Dexamethasone in Symptomatic
Patients with Primary Malignant Glioma. Presented at ASCO 2009 in Chicago, Illinois. J Clin Oncol 27:
15s. Abstract 2080.
14. Mechtler LL, Wong ET, Hormigo A, Pannullo S, Hines V, Milsted R, O’Connor PC, Ryan RP, Recht L.
A Long-Term Open-Label Extension Study Examining the Steroid-Sparing Effects of Corticorelin

Laszlo Mechtler, MD
Curriculum Vitae
Acetate in Patients with Cerebral Tumors. Presented at ASCO 2009 in Chicago, Illinois. J Clin Oncol 27:
15s. Abstract 2079
15. Recht LD, Mechtler LL, Phuphanich S, Hormigo A, Hines V, Milsted R, O’Connor PC, Ryan RP, Wong
ET. A Placebo-Controlled Study Investigating the Dexamethasone-Sparing Effects of Corticorelin
Acetate in Patients with Primary or Metastatic Brain Tumors. Presented at ASCO 2009 in Chicago,
Illinois. J Clin Oncol 27: 15s. Abstract 2078
16. Farooq O, Mechtler LL, Saikali N, Lincoff N. Novel Treatment for Radiation Optic Neuropathy with IV
Bevacizumab. Presented at AAN meeting 2011 in Honolulu, Hawaii. J Neuroophthalmol. 2012 Dec;
32(4): 321-4.
17. McVige J, Mechtler LL. A Case Series Report of Mass Psychogenic Movement Disorder from LeRoy,
New York. Presented at the annual Child Neurology Society Meeting, 2012, Huntington Beach,
California.
18. Fabiano A, Mechtler LL, Plunkett R, Fenstermaker R. Cost Analysis of a Visual Field Analyzer in a
Neurosurgical Clinic. Presented at the AAN Annual Scientific Meeting in New Orleans, Louisiana 2013.
19. Chapman N, Pinter N, Mechtler LL. Single Case Report and Literature Review of Intramedullary
Melanotic Schwannoma. Presented at the annual American Society of Neuroimaging Meeting 2014,
Sarasota, FL.
20. Jani R, Mechtler LL. A rare case of giant AVM and Pineal Germinoma. Presented at the annual
American Society of Neuroimaging Meeting 2014, Sarasota, FL.
21. Pfiffner T, Mechtler LL. A case of Assimilation of the Atlas. Presented at the annual American Society
of Neuroimaging Meeting 2014, Sarasota, FL.
22. Mechtler LL. A Randomized Open-Label, Parallel Two-Arm Study Evaluating the Efficacy of H.P.
Acthar Injection Gel in the Treatment of Adults with Intractable Chronic Migraine. To be presented at the
annual American Academy of Neurology Meeting 2014, Philadelphia, PA.
23. Cady R, Mechtler L, Mahmoud R, et al. Pooled Analyses of Randomized, Double-Blind, Placebo-
Controlled Studies of A Breath Powered Nasal Delivery System Containing 22 mg Sumatriptan Powder
(AVP-825) in the Treatment of Episodic Migraine. Presented at the annual American Academy of
Neurology Meeting 2015, Washington, DC.
24. Tepper SJ, Silberstein SD, Mechtler L, et al. Predefined Exploratory Outcomes From the Study of Non-
invasive Vagus Nerve Stimulation for the Acute Treatment (ACT1) of Cluster Headache. Presented at the
annual American Headache Society Meeting 2015, Washington, DC.
25. Cady R, Djupesland P, Mechtler L, et al. Pooled analyses of randomized, double-blind, placebo-
controlled studies of a Breath Powered™ nasal delivery device containing 22 mg sumatriptan powder
(AVP-825) in the treatment of episodic migraine [AAN 2015 abstract P1.315]. Neurology. 2015;84(14
Suppl).
26. Cady RK, Djupesland PG, Mahmoud RA, Messina J, Mechtler LL, Siegert S, Siffert J, Shulman K.
Pooled analyses of randomized, double-blind, placebo-controlled studies of a Breath Powered nasal
delivery system containing 22 mg sumatriptan powder (AVP-825) in the treatment of episodic migraine
[SGIM 2015 abstract]. J Gen Intern Med. 2015; 30(2 Suppl):S229.
27. Cady R, Rothrock J, Mechtler, L, et al. A Randomized, Open-Label, Parallel Two-Arm Study Evaluating
the Efficacy of H.P. Acthar Injection Gel in the Treatment of Adults with Intractable Chronic Migraine.
Presented at the annual American Academy of Neurology meeting 2016, Vancouver, BC, Canada.

Laszlo Mechtler, MD
Curriculum Vitae
INVITED PRESENTATIONS AT NATIONAL MEETINGS:
• Gengo FM, Gabos C and Mechtler LL. “The Effects of Diphenhydramine and Increasing Doses of
Cetrizine on Simulated Automobile Driving.” Presented at the Annual Meeting of the American Academy
of Neurology. Anaheim, CA. March 1988.
• Mechtler LL, Yung WK, Gleason MJ. “IV Carboplatin for Recurrent Malignant Glioma: A Phase II
Study.” Poster presentation at the Annual American Academy of Neurology Meeting, Chicago, Illinois,
1989.
• Schmidt R, Mechtler LL, Kinkel PR, Fazekas F, Weymann C and Kinkel WR. “Cognitive Impairment
after Hemispheric Stroke: A Clinical and Computed Topographic Study.” Presented at the 44th
Annual
Meeting of the American Academy of Neurology. San Diego, CA. May 1992.
• Mechtler LL. “A Diagnostic Dilemma! When to Worry About a Headache.” Presented at the Annual
Meeting of the Hungarian Medical Association of America, Sarasota, Florida. October 1993.
• Patel M, Truax B, Kinkel PR, Shin K and Mechtler LL. “Magnetic Resonance Imaging of Intravascular
Malignant Lymphomatosis (IML) Presenting as a Spinal Cord Syndrome.” Poster presentation at the Sixth
Canadian Neuro-Oncology Meeting, Lake Louise, Alberta, Canada. May 1994.
• Mechtler LL, Withiam-Leitch S, Shin K, and Kinkel WR. “MRI of the Cauda Equina in the Paraneoplastic
Anti-Hu Syndrome.” Poster presentation at the Sixth Canadian Neuro-Oncology Meeting, Lake Louise,
Alberta, Canada. May 1994.
• Grand W, Plunkett J, Munschauer F, Ostrow P, Mechtler LL and Shin K. “Giant Encephalitic Tumor –
Like Demyelinating Lesions of the Brain.” Poster presentation at the Sixth Canadian Neuro-Oncology
Meeting, Lake Louise, Alberta, Canada. May 1994.
• Shin K, Mechtler LL, West C and Grand W. “Brain Tumor Assessment Index.” Poster presentation at the
Sixth Canadian Neuro-Oncology Meeting, Lake Louise, Alberta, Canada. May 1994.
• Patel M, Truax B, Kinkel PR, Shin K and Mechtler LL. “Neuroimaging of the Intravascular Malignant
Lymphomatosis of the Spine.” Poster presentation at the First Congress of the European Association for
Neuro-Oncology, Maastricht, The Netherlands, October 1994.
• Shin K, Mechtler LL, West C and Grand W. “Brain Tumor Assessment Index.” Poster presentation at the
First Congress of the European Association for Neuro-Oncology, Maastricht, The Netherlands, October
1994.
• Mechtler LL, Withiam-Leitch S, Shin K, and Kinkel WR. “MRI of the Cauda Equina in the Paraneoplastic
Anti-Hu Syndrome.” Poster presentation at the First Congress of the European Association for Neuro-
Oncology, Maastricht, The Netherlands, October 1994.
• Shin K, Sibata C, West C, Mechtler LL and Grand W. “Thyroid Doses Due to Radiosurgery of the Brain.”
Poster presentation at the First Congress of the European Association for Neuro-Oncology, Maastricht, The
Netherlands, October 1994.
• Patrick JT, Mechtler LL, Budny J, Patel M, Heffner, R and Bates VE. “MRI in Granular Cell Tumor
(Choristoma) of the Neurophypophysis.” Poster presentation at the Annual Meeting of the American
Society of Neuroimaging, San Juan, Puerto Rico. March 1995.

Laszlo Mechtler, MD
Curriculum Vitae
• Patrick JT, Mechtler LL, Kinkel PR, Bates VE, Holmlund T and Kinkel WR. “Magnetic Resonance
Imaging Reveals T2 Shortening in the Motor Cortex and T2 Lengthening in the Subcortical White Matter in
Amyotrophic Lateral Sclerosis.” Poster presentation at the Annual Meeting of the American Society of
Neuroimaging, San Juan, Puerto Rico. March 1995.
• Mechtler LL. “SPECT in Patients with Central Nervous System Lymphoma and Toxoplasmosis,” lecture
presentation at the Annual Meeting of the American Society of Neuroimaging, San Juan, Puerto Rico.
March, 1995.
• Mechtler LL. “Neuroimaging of Lumbosacral Enhancing Nerve Roots,” lecture presentation at the
Annual Meeting of the American Society of Neuroimaging, San Juan, Puerto Rico. March, 1995.
• Bakshi R, Mechtler LL, Miletich RS, Shin KH, Gibbons KJ. “Radiation Optic Neuropathy: Correlation of
PET and MRI Findings.” Neurology 1996; 46 (suppl 1): A 245.
• Wright PD, Bakshi R, Kinkel PR, Pullicino PM, Bates VE, Mechtler LL, Sirotkin I, Kinkel WR. Cranial
magnetic resonance imaging findings in bacterial endocarditis: The neuroimaging spectrum of septic
cerebral emboli in twelve cases (abstract). (Presented at the 1998 annual meeting of the American Society
of Neuroimaging, Orlando, Florida) Journal of Neuroimaging 1998;8:120
• Grand Rounds, Okinawa, Japan: Neuro-Oncology. Invitation as a visiting professor. 2004
PAPERS/LECTURES PRESENTED:
October 1992 Hungarian Medical Association of America, Sarasota, Florida, “Treatment of
Parkinson’s Disease with Sinemet CR.”
January 1993 Neurology Grand Rounds at Buffalo General Hospital, “CNS Intravascular
Lymphomatosis”
March 1993 Neurology Grand Rounds, Buffalo General Hospital, “Intravascular Malignant
Lymphoma”
April 1993 Millard Fillmore Hospital Department of Rehabilitation, “Neurorehabilitation of
Patients With Brain Tumors”
April 1993 Hyatt Regency Hotel, Buffalo, New York – Headache Teaching Program,
“Diagnosis and Treatment of Secondary Headaches”
April 1993 Syracuse, New York “Pathophysiology of Secondary Headaches.”
April 1993 Roswell Park Cancer Institute, “Neuroimaging in Neuro-Oncology”
April 1993 Roswell Park Cancer Institute, Department of Medicine, “Brain Tumors”
May 1993 Jones Memorial Hospital, Wellsville, NY, “Migraines”
June 1993 Second Annual Neuroscience Nurses Teaching Day (AANN), Grand Island
Holiday Inn, “Clinical Manifestations of Brain Tumors: Diagnosis and Work-up”
July 1993 Moonbrook Country Club, Jamestown, New York, “Migraine Awareness”
sponsored by GlaxoSmithKline Pharmaceuticals

Laszlo Mechtler, MD
Curriculum Vitae
August 1993 Neurosurgery Grand Rounds, Millard Fillmore Hospital, “Chemotherapy in Brain
Tumor”
October 1993 Department of Radiation Oncology Grand Rounds, Roswell Park Cancer Institute,
“Epidural Spinal Cord Compression”
November 1993 Seefeldt Symposium on Neurodegenerative Disease, SUNYAB School of
Medicine and Biomedical Science, “Cancer and the Nervous System”
June 1994 Third Annual Neuroscience Teaching Day (AANN), Grand Island Holiday Inn
“Neoplasms of the Spinal Cord”
January 1995 Department of Medicine Research Group, Millard Fillmore Hospital, “Research
in Brain Tumors”
February 1995 Neuroimaging Fellows, Lucy Dent Imaging Center, “Neuroimaging of Spine
Tumors”
February 1995 Varian 3rd
Annual Asian Conference, Bangkok, Thailand, “Advances in the
Treatment of Epidural Spinal Cord Compression”
February 1995 Department of Radiation Oncology, Seoul, South Korea, “Evaluation of Spinal
Cord Tumors With MRI and PET”
March 1995 ER Department Grand Rounds, Buffalo General Hospital, “ER Evaluation of
Cancer in the Spine”
October 1995 Attended the 27th
Annual Scientific Meeting of the HMAA
April 1996 Board Meeting of the HMAA, April 1996
February 1996 “Cancer Effecting the Nervous System.” Hong Kong
March 1996 “Blood-Brain Barrier Modification in the Treatment of Brain Tumors.” Sydney,
Australia
October 1996 “RMP-7 & Carboplatin in the Treatment of Malignant Gliomas.” Sarasota, Florida
October 1996 28th
Annual Scientific Meeting of the HMAA. Lecture presented: “RMP-7 and
Carboplatin in the Treatment of Malignant Gliomas.” Sarasota, Florida
April 1997 “Organic Headaches,” Sponsored by GlaxoSmithKline and Fanny’s Restaurant for
Primary Care Physicians
May 1997 Neurology Grand Rounds – Buffalo General Hospital – “Blood Brain Barrier
Modification”
May 1997 “Treatment of Migraines,” Sponsored by GlaxoSmithKline for Primary Care
Physicians Little White House Restaurant
May 1997 “Environment Factors in Brain Tumors,” ECC North for Conference on Cancer and
the Environment
December 1999 “Migraines” South Buffalo Mercy Grand Rounds
January 2000 “Chemo-Therapy in Brain Tumors” Millard Fillmore Hospital – Neurosurgery
Grand Rounds
January 2000 “Neuroimaging of Cancer Related Dementia” Grand Rounds Neurology
January 2000 American Society of Neuro-Imaging, San Juan, Puerto Rico
February 2000 “Brain Tumors” American Society of Neuro-Imaging, Scottsdale, Arizona
February 2000 “Spinal Tumors and MRI” American Society Neuro-Imaging, Scottsdale, Arizona

Laszlo Mechtler, MD
Curriculum Vitae
August 2000 Cerebrovascular Ultra Sound and Stroke Management, New York, New York
February 2001 “MRI in Brain Tumors” American Society of Neuro-Imaging, Las Vegas, Nevada
March 2001 “Migraine: Early Intervention” Grand Rounds, Millard Fillmore Gates Hospital
March 2001 Hungarian Medical Association Annual Meeting-Director/Presenter
April 2001 “Migraine Management” Internal Medicine Grand Round, ECMC
April 2001 Migraine Special Interest Board for GlaxoSmithKline, Glenn Dorn Bradford,
Pennsylvania
June 2001 CNS Neoplasms Overview, Grand Rounds, VA Hospital
June 2001 “Combinations with Temodar” for Schering-Plough, Hershey, Pennsylvania
July 2001 “Treatment with Temodar” for Schering-Plough, JFK Hospital Palm Springs,
California
October 2001 “Migraine & Triggers” for GlaxoSmithKline, Marriott Hotel, Buffalo, New York
October 2001 American Society of Neuro-Imaging, Ponte Verde Beach, Florida
November 2001 Society of Neuro-Oncology Meeting, Washington, D.C.
January 2002 Headache Symposium, CME Program Director/Presenter, Marriott Hotel, Buffalo,
NY
February 2002 “Migraines” Fisher Price Employees sponsored by Independent Health
February 2002 Schering-Plough Advisory Board Meeting, San Diego, California
February 2002 Grand Rounds for Rehab Medicine, ECMC, Buffalo, NY
March 2002 American Society of Neuro-Imaging, Director/Presenter, “Hands on Workshop”
April 2002 “New Treatments with Temodar: for Schering-Plough, Greensboro, South Carolina
April 2002 “New Anti-Epileptics” for Elan Pharmaceuticals, Pranzo Restaurant, Buffalo, NY
April 2002 “Differential Diagnosis and Treatment of Migraine”, “Efficacy and Safety of the Use
of Triptans” for Pharmacia, Canandaigua Inn on the Lake
March 2003 American Society of Neuroimaging, New Orleans, Louisiana
March 2003 II International Conference, “Future Trends in Treatment of Brain Tumors”, Padua
University Hospital, Padua, Italy
June 2003 “Overview of Migraines and Treatment Options” Headache Symposium Sponsored
by Dent Neurologic Institutes Headache Clinic and Pfizer Pharmaceuticals, Marriott
Hotel, Amherst, NY
November 2003 Hungarian Medical Association of America Annual Meeting, Sarasota, Florida
January 2004 American Headache Society Annual Meeting, Cancun, Mexico
January 2004 “CT/MRI in Primary and Secondary Headaches”, Speaker, American Headache
Society, Cancun, Mexico
January 2004 American Society of Neuroimaging Annual Meeting, Phoenix, Arizona
February 2004 Visiting Professor Lecture, Okinawa, Japan
March 2004 Hungarian Medical Association of America Annual Meeting, Sarasota, Florida
November 2004 Society of Neuro-Oncology Annual Meeting, Toronto, Canada
January 2005 American Headache Society Annual Meeting, Las Vegas, Nevada

Laszlo Mechtler, MD
Curriculum Vitae
March 2005 American Society of Neuroimaging Annual Meeting, Program Speaker, San Diego,
California
March 2005 “MRI Hands-on Workshop”, American Society of Neuroimaging, San Diego,
California
April 2005 American Academy of Neurology Annual Meeting, Miami, Florida
September 2005 Community Headache Awareness Program, Sheraton Four Points, Buffalo, New
York
November 2005 Symposium, “Neurology Updates for Primary Care Physicians” Niagara on the Lake,
Canada
December 2005 Grand Rounds Meeting, Pfizer, Kalamazoo, Michigan
March 2006 “MRI Hands-on Workshop”, American Society of Neuroimaging, San Diego,
California
April 2006 “Spine Neuroimaging-Clinical-Radiological Correlation”, American Academy of
Neurology, San Diego, California
April 2006 “Neuroimaging of Headaches”, American Academy of Neurology, Half-Day Course-
Director, San Diego, California
December 2006 Buffalo General Hospital, Resident Lecture, “Brain Tumors / Oncology”
December 2006 Kenmore Mercy Hospital, Buffalo, NY, Grand Rounds “Neuroimaging and Brain
Tumors”
January 2007 “Neuro-Oncology Symposium”, American Society of Neuroimaging, Director,
Miami, Florida
January 2007 “Introduction to High Resolution Sonography for Peripheral Nerve Disorders”,
American Society of Neuroimaging, Miami, Florida
January 2007 “MRI Course (Part II)”, American Society of Neuroimaging”, Miami, Florida
February 2007 University of Buffalo Department Neurosurgery, Grand Rounds
April 2007 “Spine Neuroimaging: Clinical-Radiological Correlation”, American Academy of
Neurology, Director, Boston, Massachusetts
May 2007 “Update in Neuroimaging: Essentials and Beyond-Part I”, American Academy of
Neurology, Boston, Massachusetts
October 2007 Lecture Series Presentations, American Society of Neuroimaging, for Dr. Greenberg
November 2007 ASRA Pain Medicine Meeting and Workshops, Boca Raton, Florida
April 2008 “Spine Neuroimaging: Clinical-Radiological Correlation”, American Academy of
Neurology, Chicago, IL , Faculty
April 2008 “Neuroimaging Spinal Tumors ”, “Neuroimaging Brain Tumors” American
Academy of Neurology, , Chicago, IL, Director
May 2009 International Neuroscience and Addiction Conference, “Imaging of Cognitive
Disturbances”, London, England
October 2009 DENT CME Symposium “Headaches”
January 2010 ASN Sponsored Neuroimaging Fellowship Educational Rounds “Neuro Cutaneous
Syndrome” via Telephone
January 2010 ASN Annual Meeting “Imaging of Cognitive Disturbances”, ”Intracranial
Neoplasm”, “ Advanced Imaging in Neuro-Oncology”

Laszlo Mechtler, MD
Curriculum Vitae
April 2010 AAN Annual Meeting “Advanced Neuroimaging in Brain Tumors”, “Neoplasm of
the Spine”
April 2010 Medical Students, Roswell Park “ Oncology for Scientists”
May 2010 Speaker for Headache Seminar, Buffalo, NewYork, Millenium Hotel
January 2011
April 2011
January 2012
April 2012
August 2012
August 2012
American Society of Neuroimaging Annual Meeting, Saint Louis, Missouri: “PFO
Detection by MRI”, “Spine Tumors”, “Intracranial Neoplasm”
AAN Annual Meeting, Honolulu, Hawaii “Neuroimaging Fellowships” and “NQF
Of Neuro-Oncologic Disorder”
ASN Annual Meeting, Miami, Florida “Intracranial Neoplasm”, “Cerebral Venous
System Evaluation by Transcranial Color Coded Duplex and Magnetic Resonance
Venography: MVR”
AAN Annual Meeting, New Orleans, Louisiana “Update in Neuroimaging:
ntials and Beyond Part I & II”, “Case Studies: Neuroimaging”, “Spine Neuroimaging: Clinical-
Correlation”
Pituitary Conference “The Zebras of Sellar Pathology” Buffalo General Hospital,
Buffalo, New York
Ukrain Neuroradiology Society of American Medicine “Advanced Neuroimaging of
Brain Tumors”, Lviv, Ukraine
October 2012
October 2012
October 2012
November 2012
January 2013
April 2013
January 2014
April 2014
January 2015
April 2015
January 2016
April 2016
Concussion Symposium- Moderator, Ralph Wilson Field House, Orchard Park, NY
Wisconsin Neurological Society Meeting “Neuropsychiatric Syndrome: LeRoy
Madison, Wisconsin
Hungarian Medical Association of America (HMAA) Meeting “Mass Psychogenic
Illness: Effects of Social Media” Sarasota, Florida
Annual Breast Cancer Symposium “Chemo Brain” Amherst, New York
ASN Annual Meeting, Las Vegas, Nevada “Advanced Imaging of Brain Tumors”
“MRI and Ultrasound Imaging of the Peripheral Nervous System” and “Imaging of
Spinal Cord Lesions”
AAN Annual Meeting, San Diego, California “Advanced Neuroimaging of Brain
Tumors” “Intramedullary Tumors” – Course Director
ASN Annual Meeting, Sarasota, FL “ What’s New in Neuro-Oncology: Spine and
Brain”
AAN Annual Meeting, Philadelphia, PA “Neuroimaging of Headaches” (Course
Director, Neuroimaging for the General Neurologist: Brain)
ASN Annual Meeting, Scottsdale, AZ. ‘Brain Tumors’ & ‘Spine Tumors’
AAN Annual Meeting, Washington, DC. Course Director: Neuroimaging for the
General Neurologist: Brain., Lectures: ‘Neuroimaging of Brain Tumors’ & ‘Pituitary
Disease Imaging’
ASN Annual Meeting, Orlando, FL. “Neuro-imaging Differential Diagnosis of
Intracranial and Spinal Masses”
AAN Annual Meeting, Vancouver, BC. “Neuroimaging in Headache” and
“Neuroimaging of TBI”

Laszlo Mechtler, MD
Curriculum Vitae
BROADCAST MEDIA PRESENTATIONS:
May 1994 Niagara University Cable Television Station – Three half-hour segments taped for the
American Cancer Society: First segment – “An Overview of Brain Tumors”, Second
segment – “Oncologic Pain Syndromes (Part 1)”, Third segment - “Oncologic Pain
Syndromes (Part 2).”
May 1994 WGR Radio 550. Live on-air interview on cervical spine injury. Host Tom Bauerle.
Weekly guest throughout the month.
June 1994 ABC affiliate – WKBW TV – “Ask Seven Doctors.” Question and answer interview on
Neurologic topics
May 1999 WIVB-TV Channel 4 “For the People” Host Anne Gioia Brain Tumor Awareness Week
Guests: Steven Mathews & Linda Scime
November 2001 WKBW TV Channel 7 “Migraines”
April 2002 WJJL Radio “Get to Know Your Doctor”
May 2003 AM Buffalo TV Live Channel 7
June 2003 WNY Live TV Channel 7
January 2006 Citadel Communications, 5 Channel Radio Interview, “Headaches”
July 2007 Channel 7 PM Buffalo, “Kilimanjaro”
November 2007 Live Radio Interview, 97 Rock, “Kilimanjaro”
January 2010 Taping for “Roswellness Radio Show”
January 2012 “Tom Bauerle Show”
January 2012 Taping for the USA Today Show with Matt Lauer, on the LeRoy Cases
January 2012 Live Interview, Fox News, “Mystery Illness Diagnosed as ‘Mass Hysteria” –LeRoy Cases
January 2012 Live Interview, Anderson Cooper Talk Show- CNN, LeRoy Case Discussion
January 2012 Interview, The Wall Street Journal, “Teens in Upstate New York Get Diagnosis: ‘Mass
Psychogenic Illness”
January 2012 Taping for WGRZ Channel 2, LeRoy Case Discussion
January 2012 Taping for Fuji TV, Japanese Science Documentary – LeRoy Cases
January 2012 Live Interview, Dr. Drew Show, LeRoy Case Discussion
February 2012 Live Interview, Inside Edition, LeRoy Case Discussion
July 2012 Taping for Nippon TV, Largest Japanese Network, LeRoy Case Discussion
October 2012 Taping for Raw TV, LeRoy Documentary

Laszlo Mechtler, MD
Curriculum Vitae
November 2012 Phone Interview for BBC Radio, “The Town that Caught Tourettes” documentary
February 2014 Taping for Channel 2 during ‘The Olympic Zone’ segment on Concussions
NEWSPAPER COVERAGE (LeRoy Case)
Newsweek
New York Times
USA Today
NY Post
Wall Street Journal
Huffington Post
Reuters
Buffalo News
Daily Mail UK
COVERAGE (Medical Marijuana)
WGRZ, Channel 2
WIVB, Channel 4
WKBW, Channel 7
WNLO, CW 23
Time Warner Cable
WBEN, Radio Show
Buffalo News
Business First
Buffalo Health Living
RESEARCH STUDIES:
CLOSED STUDIES:
Sponsor: RTOG-90-06
Description: A Phase III Comparison of Hyperfractionation Radiation Therapy (RT)
With BCNU and Conventional RT with BCNU for Supratentorial
Malignant Gliomas
Sponsor: RTOG-91-04
Description: A Phase III Comparison of Accelerated Hyperfractionation versus
Standard Fractionation in Patients with Brain Metastases
Sponsor: RTOG-91-10
Description: A Phase III Evaluation of Post-Operative Radiation in Low Grade
Intracranial Astrocytomas and Oligodendrogliomas
Research Type: Neuro-Oncology/Headache
Principal Investigator: Laszlo Mechtler, M.D, FAAN

Laszlo Mechtler, MD
Curriculum Vitae
Protocol: BRS-NORG
Description: Phase I and II Study of Superfractionated Radiation Therapy and
Concurrent Hydroxyurea for Recurrent Malignant Brain Tumors
Refractory in Conventional Therapy
Sponsor: BRS-NORG 9301
Description: A Phase II Study of Idarubicin in Adult Patients with Recurrent or
Progressive Malignant Glial Tumors
Sponsor: BRS-NORG (URCC 4393)
Description: A Phase I Trial of Beta-Interferon plus Radiation Therapy for Malignant
Glioma
Sponsor: RTOG-93-05
Description A Phase III Trial Comparing the Use of Radiosurgery Followed by
conventional Radiotherapy with BCNU for Supratentorial Glioblastoma
Multiforme
Sponsor: RTOG-91-04
Description: A Phase III Comparison of Accelerated Hyperfractionation vs. Standard
Fractionation in Patients with Brain Metastases
Sponsor: ALK-031
Description: A Multi-Cent Open Label, Single Arm, Phase II Study of RMP-7 and
Carboplatin, Administered Intra-arterially for the Treatment of Recurrent
Malignant Glioma
Start/End: 1995-1997
Sponsor: ALK-017
Description: A Randomized, Double-Blind Placebo Controlled Phase II Study RMP-7
in Combination with Carboplatin Administered Intravenously for
Treatment of Recombinant Glioma
Description: A Phase II Study to Evaluate the Efficacy and Safety of RSR 13
Recruitment: Enlisted patients receiving standard cranial radiation therapy for Brain
Metastases
Sponsor: Allos Pharmaceuticals
Description: A Phase II Study to Evaluate the Efficacy and Safety of RSR-13
Administered to Patients Receiving Standard Cranial Radiation for
Glioblastoma Multiforma
Start/End: December 1999- November 2000
Sponsor: NTI, Inc
Description: A Phase II Randomized Dose Ranging Causes for Control Trial of
Human Corticotropin-Releasing Factor (hCRF) in Symptomatic Brain
Tumor Patients

Laszlo Mechtler, MD
Curriculum Vitae
Description: A Multi-Center, Randomized, Controlled Phase III Study to Assess the
Efficacy and Safety of Cereport in Combination with Carboplatin in
Comparison of Standard of Care for Neo-Adjuvant Treatment of Newly
Diagnoses Glioblastoma Multiforma
Sponsor: Schering-Plough, Inc
Description: A Temodal® (SCH52365) Treatment Protocol for Patients with
Relapsed or Progressive High Grade Malignant Glioma or Advanced
Metastatic Malignant Melanoma
Description: A Phase I/II Trial of Temodar and Escalating Doses of Oral VP-16 for
Patients with Recurrent Gliomas
Description: A Phase III, Randomized, Open Label, Comparative Study of Standard
Whole Brain Radiation Thearpy with or without RSR13 in Patients iwth
Brain Metastases
Description: A Phase II Study of Temodar Prior to PCV Chemotherapy in Adults with
Newly Diagnoses, Recurrent/Progressive Oligodendral Glioma Tumors
of the Central Nervous System
Description: Multi-Center, Comparative Trial of Temodar versus Temodar and
Thalidomide in Newly Diagnosed Glioblastoma Multiforme
Description: Phase II Study Evaluating the Effectiveness of Gamma Knife
Radiosurgery and Temozolomide for Patients with 1-4 Unresected Brain
Metastases Followed by Temozolomide
Description: A Phase III Randomized, Open-Label Comparative Study of Standard
Whole Brain Radiation Therapy with Supplemental Oxygen, with or
without Concurrent RSR13 (efaproxiral), in Women with Brain
Metastases from Breast Cancer
Protocol: GlaxoSmithKlein, Inc
Description: A Randomized, Double Blind, Placebo Controlled, Parallel-Group,
Single Attack Study to Evaluated the Onset of Efficacy of a New
Formulation of Sumatriptan Tablets 50 mg and 100 mg in the Acute
Treatment of Migraine
Start/End: January 2004 - 2006
Protocol: NTI, Inc

Laszlo Mechtler, MD
Curriculum Vitae
Description: A Phase III randomized, Double Blind Study Comparing Human
Corticotropin-Releasing Factor (hCRF) to Placebo for Control of
Symptoms Associated with Peritumoral Brain Edema in Patients with
Malignant Brain Tumors who Require Chronic Administration of High-
Dose Dexamethasone
Start/End: Closed
Sponsor: NTI, Inc.
Protocol: NTI-0302
Description: A Phase III Randomized, Double-Blind Study Comparing Human
Primary Malignant Gliomas –– Closed 1/08.
Sponsor: NTI, Inc.
Protocol: NTI-0303
Description: A Phase III Randomized, Double-Blind Study Comparing Human
Malignant Brain Tumors who Require Chronic Administration of High-
Dose Dexamethasone – 29 patients – Highest enrollment in the world
enrolling 40% of all the patients – Closed 2/08.
Sponsor: NTI, Inc.
Protocol: NTI-0501
Description: An Open Label, Extended-Use Study of Human Corticotropin-Releasing
Factor (hCRF) Intended for Patients who participated in the
Dexamethasone-Sparing Studies NTI-0302 and NTI-0303 - Closed.
Sponsor: Celtic PharmaDevelopment Services America, Inc.
Protocol: NTI-0501: Imaging Data Submission
Description: An Open Label, Extended-Use Study of Human Corticotropin-Releasing
Factor (hCRF) Intended for Patients who participated in the
Dexamethasone-Sparing Studies NTI-0302 and NTI-0303, or other
designated Studies - Closed.
Sponsor: Celldex Therapeutics, Inc.
Protocol: CDX110-03
Description: A Phase II/III Randomized Study of CDX-110 with Radiation and
Temozolomide in Patient with Newly Diagnosed Glioblastoma
Multifome 12/09– Closed.
Sponsor: AstraZeneca
Protocol: AZD2171
Description: A Phase III, Randomized, Parallel Group, Multi-Center Study in
Recurrent Glioblastoma Subjects to Compare the Efficacy of AZD-2171
[RECENTIN] Monotherapy and Combination of AZD-2171 with

Laszlo Mechtler, MD
Curriculum Vitae
Lomustine to the Efficacy of Lomustine Alone – Start Date 11/08 -
Closed.
Sponsor: Eli Lilly & Company
Protocol: H6Q-MC-JCBF
Description: A Randomized Phase III Study of Enzastaurin HCI versus Lomustine in
the Treatment of Recurrent, Intracranial Glioblastoma Multiforme–
Closed.
Sponsor: OrthoMcNeil Pharmaceuticals, Inc
Protocol: CAPSS-334
Description: Efficacy of AXERT (Almotriptan Malate) in the Acute Treatment of
Migraine: A Pilot Study of the Potential Impact of Preventative Therapy
with Topamax (Topiramate) – Closed.
Sponsor: OrthoMcNeil Pharmaceuticals, Inc
Protocol: CAPSS-381
Description: Topiramate Intervention to Prevent Transformation of Episodic
Migraine: The Topiramate INTREPID Study – Closed.
Sponsor: UCB Pharmaceuticals, Inc
Protocol: IV Levetiracetam
Description: Treatment of Acute Migraine Headache with Intravenous Levetiracetam:
Initial Outpatient Experience – Closed.
Sponsor: Merck & Co.
Protocol: MK-0974-016
Description: A Phase III, Multi-Center, Randomized, Placebo-Controlled Clinical
Trial to Study the Safety and Efficacy of Oral MK-0974 in the Acute
Treatment of Migraine With or Without Aura –Closed.
Sponsor: Merck & Co.
Protocol: MK-0974-012
Description: A Multi-Center, Double-Blind, Active-Controlled, Parallel Group Study
to Examine the Safety, Tolerability and Efficacy of Oral MK-0974 for
the Long Term Treatment of Acute Migraine With or Without Aura –
Closed.
Sponsor: GlaxoSmithKline, Inc
Protocol: TRX106573
Description: A Study of Combination Product Containing Sumatriptan Succinate and
Intolerance to Short Acting Triptans – Closed
Protocol: TXA107977
Description: A Long-Term Safety Study of a Combination Product Containing
Sumatriptan Succinate and Naproxen Sodium for the Treatment of
Migraine in Adolescents – Started 2/08-Closed 8/08

Laszlo Mechtler, MD
Curriculum Vitae
Protocol: TRX109011
Description: A Multicenter, Randomized, Double-Blind, Double-Dummy, Placebo-
Controlled, Crossover, Three-Attack, Outpatient Study in which
TREXIMA will be Compared to Butalbital-Containing Combination
Medication for the Acute Treatment of Migraine Headache – Started
9/08-Closed 7/09
Protocol: TXA107979
Description: A Randomized, Multicenter, Placebo-Controlled, Parallel Group Study
to Evaluate the Efficacy and Safety of a Combination Product
Containing Sumatriptan and Naproxen Sodium for the Acute Treatment
of Migraine in Adolescents – Started 1/09 – Closed.
Sponsor: NINDS-NIH
Protocol: Chronic Migraine Treatment Trial
Description: A Double-Blind, Placebo Controlled, Randomized Study to Assess the
Efficacy of Propranolol in Combination with Topiramate for Reducing
the Number of Severe Headaches in Long Term – Started 1/09- 2/1
Closed
Sponsor: St. Jude Medical
Protocol: PREMIUM
Co-PI: Henry Meltser, M.D.
Description: A Prospective, Randomized Investigation to Evaluate the Incidence of
Headache Reduction in Subjects with Migraine and PFO Using the
AMPLATZER PFO Occluder, Compared to Medical Management.
Start/End: February, 2009/ May 14th
, 2013
Sponsor: OptiNose US, Inc/PharmaNet
Protocol: OPN-SUM-MIG-3301
Description: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study
Evaluating the Efficacy and Safety of a Single 20 mg Dose of
Sumatriptan Powder Delivered Intranasally with the Bi-directional
Device in Adults with Acute Migraine With or Without Aura.
Start/End: January 19th
, 2012/Closed July 10th
, 2012
Sponsor: Spectrum Pharmaceuticals
Protocol: SPI-LUC-11-01
Descriptions: An International, Multi-Center, Randomized, Double-Blind, Placebo
Controlled Phase II Study to Evaluate the Safety and Efficacy of
Lucanthone Administered as an Adjunct to Radiation and
Temozolomide for Primary Therapy of Glioblastoma Multiforme.
Start/End: February 24th
, 2012/ July 1st, 2013(discontinued by the Sponsor due to
safety issues)

Laszlo Mechtler, MD
Curriculum Vitae
Sponsor: OptiNose US, PharmaNet-i3
Protocol: OPN-SUM-MIG-3302
Description: A Randomized, Double-Blind, Double-Dummy, Active-Controlled,
Cross-Over Study Evaluating the Efficacy and Safety of 20 mg
Sumatriptan Powder Delivered Intranasally with the Bi-directional
Device Compared with 100 mg Sumatriptan Tablets in Adults with
Acute Migraine with or Without Aura
Start/End: August 27th
, 2012/ September 23rd
, 2013
Protocol: CDX110-05
Description: Expanded Access (Compassionate Use) Treatment Protocol
Rindopepimut (CDX-110)
Start/End: November 6th
, 2012/ March 12th
, 2013
Sponsor: Allergan (North America)
Protocol: GMA-BTX-CM-10-001 – Phase IV
PI: Laszlo Mechtler, M.D.
Description: An Open-Label, Multicenter Study of the Long-Term Efficacy, Safety
and Tolerability of BOTOX (onabotulinumtoxinA) for the Prophylaxis
of Headaches in Adult Patients with Chronic Migraine
Start/End: February 12th
, 2013/September 4th
, 2013
Sponsor: Allergan
Protocol: GMA-BTX-CM-12-545
Description: Use of the Chronic Migraine Impact Questionnaire (ACM-I) to Assess
Patient-Treatment Benefit of BOTOX (Botulinum Toxin Type A) in
Adult Patients with Chronic Migraine – Pilot Study
Start/End: June 3rd
, 2013/March 7th
, 2014
Sponsor: ElectroCore, LLC
Protocol: CH-US-01 – Pivotal Study – Phase III
Description: Non-Invasive Neurostimulation of the Vagus Nerve with the
GammaCore Device for the Treatment of Cluster Headache
Start/End July 12th
, 2013/February 12th
, 2014
Protocol: TREXIMET
Description: A Parallel, Two-Arm, Double-Blind, Placebo Study Examining the
Efficacy of Sumatriptan with Naprosyn in the Treatment of Migraine
with Aura.
Start/End September, 2009/Closed
ONGOING STUDIES:
Protocol: CDX110-04
Descriptions: An International, Randomized, Double-Blind, Controlled Study of
Rindopepimut/GM-CSF with Adjuvant Temozolomide in Patients with

Laszlo Mechtler, MD
Curriculum Vitae
Newly Diagnosed, Surgically Resected, EGFRvIII-positive
Glioblastoma.
Start/End: November 11th
, 2011/Ongoing
Sponsor: Cincinnati Children’s Hospital Medical Center
Protocol: CHAMP- Phase III
Description: Amitriptyline and Topiramate in the Prevention of Childhood Migraine
(The CHAMP Study)
Start/End: October 17th
, 2012/Ongoing
Sponsor: Questcor Pharmaceuticals, Inc.
Protocol: ACTHAR-
Description: A Randomized, Open-Label Parallel Two-Arm Study Evaluation the
Efficacy of HP Acthar Injections Gel in the Treatment of Adults with
Intractable Chronic Migraine
Start/End June 2013/Ongoing
Sponsor: Neuro-cool, Trauma-Tec Inc
Protocol Acute Migraine
Description: A Non-Randomized, Non-Controlled, Open-Label Pilot Study
Examining the Safety and Efficacy of Selective Head and Brain
Cooling Treatment of Acute Migraine Headache
Start/End Pending IRB approval
Sponsor: Roswell Park Initiated trial with a grant associated from the
American Cancer Society.
Protocol: Malignant Glioma
Description: Phase 1 Study of Safety, Tolerability and Immunological Effects of
SVN53-67/M57-KLH (012410-2) in Patients with Survivin-Positive
Malignant Gliomas
Start/End: November 2012/Ongoing

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