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Designers Light Forum
Treat Your Building As A Patient
Clifford J. Yahnke, Ph.D.
28-Mar-17
Credit(s)	earned	on	completion	of	
this	course	will	be	reported	to	AIA	
CES	for	AIA	members.	Certificates	of	
Completion	for	both	AIA	members	
and	non-AIA	members	are	available	
upon	request.
This	course	is	registered	with	AIA	CES
for	continuing	professional	
education.	As	such,	it	does	not	
include	content	that	may	be	deemed	
or	construed	to	be	an	approval	or	
endorsement	by	the	AIA	of	any	
material	of	construction	or	any	
method	or	manner	of
handling,	using,	distributing,	or	
dealing	in	any	material	or	product.
___________________________________________
Questions	related	to	specific	materials,	methods,	and	
services	will	be	addressed	at	the	conclusion	of	this	
presentation.
This	presentation	is	protected	by	US	and	International	Copyright	laws.		
Reproduction,	distribution,	display	and	use	of	the	presentation	without	written	
permission	of	the	speaker	is	prohibited.
©	Kenall Manufacturing	and	Indigo-Clean
Copyright	Materials
Learning
Objectives
1. Identify	the	types	of	Healthcare	Acquired	Infections	(HAIs)	and	their	collective	impact	upon	the	
US	healthcare	system
2. Explain	how	infections	can	be	acquired	through	the	built	environment
3. Describe	the	range	of	solutions	to	improve	environmental	hygiene	which	are	available	to	
healthcare	providers
4. List	the	characteristics	of	specification-grade	light	fixtures	that	can	reduce	the	spread	of	
pathogens	within	the	environment	
5. Recognize	the	benefits	of	continuous	environmental	disinfection	and	the	areas	within	a	
healthcare	setting	where	it	is	best	used
At	the	end	of	the	this	course,	participants	will	be	able	to:
HEALTHCARE:	THE	NEW	WORLD	WE	
LIVE	IN...
5
US	Healthcare	Is	Being	Driven	By	Changes	In	
Reimbursement
ObjectiveAssessment
Value	Based	
Purchasing
Readmission
Reduction	
Program
Healthcare	
Acquired	
Condition	
Program
PolicyPenalties
US	Statistics	on	Healthcare	Acquired	
Infections	(HAI)
• 1	in	20	patients	acquires	an	infection	
while	in	a	US	hospital
• 1.7M	HAI’s/year	(US)
• 99,000	deaths/year	(US)
• Consuming	more	health	care	dollars	each	
year
• Estimates	vary	widely	depending	upon	
what	is	considered	cost
• Typically	accepted	cost	is	~$23K	per	
infection
• 2,225	Hospitals	=	$227M	in	withheld	
compensation
• Excludes	26,000	US	facilities	such	as:
– Ambulatory	Surgery	Centers
– Skilled	Nursing	Facilities
– Long-Term	Acute	Care
– Hospice
– Dialysis	Centers
What	is	an	HAI?
Surgical	Site	Infection	(SSI)
Catheter	Associated	Urinary	Tract	
Infection	(CAUTI)
Central	Line	Associated	Bloodstream	
Infection	(CLABSI)
Ventilator	Associated	Pneumonia	
(VAP)
HAI	Cost	by	Modality
19%
33%
32%
15%
1%
CLABSI	(+MRSA)
SSI	(+MRSA)
VAP
CDI
CAUTI
9
1Zimlichman,	E.	et	al.	“Health	Care-Associated	Infections:	A	Meta-analysis	of	Costs	and	
Financial	Impact	on	the	US	Health	Care	System”,	JAMA	Intern	Med	2013;	173:2039-46
End	of	the	Golden	Age?
Infection	Prevention	Modalities
Patient
Improved	
Handwashing	
Compliance
Antimicrobial	
Stewardship
Isolation	
Precaution	
Guidelines
Patient	&	
Staff	
Education
Targeted	
Bundles
What’s	Missing?
Host
PathogenEnvironment
• What	about	the	environment?
ROLE	OF	THE	ENVIRONMENT	IN	HAI
13
Clostridium	difficile
>	5	months	to	years
Methicillin	resistant	
Staph.	Aureus (MRSA)										
>12	months
MDR	– Gram	negative		
(e.g Acinetobacter)																			
>	30	months
Vancomycin Resistant	
Enterococci (VRE)																			
>	46	months
Norovirus
>	2	weeks
Organisms	Persist	in	the	Environment
Adapted	from	
Kramer	et.	al.	
BMC	Infect	Dis	
2006;6:130
Have	You	Ever	Wondered	How	Diseases	Spread?
Contract	Transmission	from	Patient	to	
Environment
• Acquisition	of	MRSA	after	contact	with	colonized	patient	and	
terminally	cleaned	surface
1.	Stiefel U,	et	al.	Infect	Control	Hosp Epidemiol 2011;32:185-7
2.	Donskey CJ,	Eckstein	BC.	N	Engl J	Med	2009;360:e3
3.	Boyce	JM	et	al.	Infect	Control	Hosp Epidemiol 1997;18:622-7	
4.	Bhalla A,	et	al.	Infect	Control	Hosp Epidemiol 2004;25:164-7
5.	Hayden	MK,	et	al.	Infect	Control	Hosp Epidemiol 2008;29:149-154	
Patient Surface
Role	of	the	Environment	in	HAI
0
2
4
6
8
10
12
Had	C.diff Did	NOT	Have	C.diff
Percentage	of	Patients	Who	Acquired	
C.diff
Prior	Room	Occupant
Prior	Room	Occupancy	Risk
Shaughnessy	et.	al.	Infect.	Control	Hosp.	Epidemiology	2011;32:201-206
~265%	Increased	Risk	
based	on	Prior	Occupant	
Status
A	Different	Approach…
• What	if	the	building	were	treated	as	a	
patient?
Your	Building	As	A	Patient
Patient
Improved	handwashing	
compliance
Antimicrobial	stewardship
Isolation	precaution	
guidelines
Patient	&	Staff	
Education
Targeted	Bundles
Building
Improved	surface	disinfection	
compliance
Proper	surface	disinfectant
Rooms	designed	for	infection	
prevention
Engineering	&	Facilities	Education
Location-specific	Bundles
IMPROVING	ENVIRONMENTAL	
HYGIENE
20
Improving	Environmental	Hygiene
Additional	staffing
Policies &	Procedures	
Compliance	Monitoring
Technology
21
Technology	Solutions	for	Environmental	Hygiene
Sterilization	- The	active	removal	of	all	
forms	of	life and	other	biological	agents
Disinfection	–The	active	application of	
antimicrobial	agents	to	destroy	
microorganisms
Inhibition	– The	passive	reduction	of
micro-organsim accumulation	and/or	
migration
Technology	Classifications
Sterilization
• Chemicals
Foggers
• UV
…
Disinfection
• Continuous
• HEPA Filters
• UV/Plasma	Air	
Handlers
• Visible	Light
• ...
• Episodic
• Chemicals	(e.g.	
Bleach)
• Foggers
UV	Devices
• ...
Accumulation/
Migration
• Antimicrobial	
surfaces	(e.g
copper)
• Antimicrobial	
paint
• Sealed	light	
fixtures
• Environmental	
sprays
• ...
How	Can	Light	Fixtures	Help?
• Specification-grade	light	
fixtures	which	are	sealed	and	
designed	for	infection	
prevention	can:
– Reduce	the	transmission of	
pathogens	through	the	air
– Reduce	the	accumulation of	
pathogens	upon	it	through	
cleanable	design	and	
antimicrobial	coatings
What	is	Specification-Grade	Lighting?
• Specification	grade	lighting	for	
healthcare	applications:
– Withstand	the	challenging	
environment
– Dependably	provide	the	necessary	
level	of	visual	acuity
• 4	key	Elements:
– Sealed	Enclosure	to	prevent	
ingress/egress	of	pathogens
– Sealed	mounting	to	ceiling	or	wall	to	
prevent	ingress/egress	of	pathogens
– Designed	to	be	cleanable	with	harsh	
chemicals
– Prevent	interference	critical	medical	
equipment
Listings
Listings	Insure	Performance	in	Your	Challenging	
Environment
Sealed	Enclosure	Luminaire
• Prevent	intrusion	of	
contaminants	into	
luminaire
– Dust-tight
– Waterproof
• Dynamic,	not	just	a	
static	enclosure!
Ingress	Protection	Standards
• Used	to	validate	performance	of	sealed	
enclosure	luminaires
Ensures that particles of 1 micron or
large do not enter the fixture
Protected against splashing water and
water jets
IP65 IP65
Maintain	Sealed	Room	Envelope
• Prevent	passage	of	
contaminants	between	
luminaire	and	ceiling.
– Ceiling	construction
– Mounting
– Caulking	in	place
– Gasketing (vulcanized)
– Seam	welding
Room	Envelope	Standard
• Maintain	two	inches	of	pressure	+/- 10%	for	30	
minutes
– K230	based	upon	NSF-49
Fixture	Cleanability
• Ensures	that	a	fixture	can	be	
cleaned	to	remove	pathogen	
buildup
• In	the	US,	the	National	
Sanitation	Foundation	(NSF)	
has	created	cleanability	
standards:
• NSF/ANSI	- 2	Food	Equipment	–
Section	5
• Surface	cleanability
• Resistance	to	caustic	chemicals
• Use	of	Non-toxic	materials
Where	Else	Are	Sealed	Enclosures	Best	
Used?
• The	decision	to	use	specification-grade	lighting	for	
infection	prevention	should	based	upon	three	
factors:
– The	susceptibility	of	the	patient	in	the	room	to	acquire	an	
infection
– The	need	to	restrict	the	flow	of	pathogens	into/out	of	the	
room
– The	need	to	reduce	the	fixture	as	an	environmental	source	
of	pathogens
Potential	Healthcare	Applications
Waiting	
Areas
Patient	
Rooms
Sterile	
Processing
Oncology
OR
Bone	
Marrow	
Transplant
Wound	Care	
Clinics
Triage/		
Trauma
33
Technology	Classifications
Sterilization
• Chemicals
Foggers
• UV
…
Disinfection
• Continuous
• HEPA Filters
• UV/Plasma	Air	
Handlers
• Visible	Light
• ...
• Episodic
• Chemicals	(e.g.	
Bleach)
• Foggers
• UV	Devices
• ...
Accumulation/
Migration
• Antimicrobial	
surfaces	(e.g
copper)
• Antimicrobial	
paint
• Sealed	light	
fixtures
• Environmental	
sprays
• ...
No	Touch	Disinfection	Technology
Continuous
• Air	Filters	
• UV/Plasma	air	handlers
• Copper	surfaces
• Environmental	sprays
• Visible	Light	
Episodic
• UV	Devices
• Chemical	Vapor
35
EPISODIC	VS.	CONTINUOUS	
DISINFECTION
36
Episodic	vs.	Continuous- Definition
37
Continuous
=	Total	Bacteria	Killed
(High-Level	Continuous-
Ideal,	but	not	practical)
=	Total	Bacteria	Killed
(Episodic- Practical	
implementation	of	ideal	
solution)
=	Total	Bacteria	Killed (Low-
Level	Continuous-
Compliment	to	Episodic)
“Continuous	Disinfection	Fills	the	Gaps”
(Bacteria	Killed/Time)
=
Shaded	Area	=	Total	Bacteria	Killed
Effects	of	Episodic	Disinfection	Upon	
Bacteria	Levels
38
High
Low
Bacteria	Levels
Time
Episodic	Disinfection	Applied
Regrowth
“Log	X	Kill”
Continuous	Disinfection
39
High
Low
Bacteria	Levels
Continuous	(No	Regrowth)
Time
Continuous	(With	Regrowth)
Dynamic	Equilibrium	Limit
Continuous	+	Episodic	Disinfection
40
High
Low
Bacteria	Levels
Time
Continuous	Disinfection	Applied
Episodic	Disinfection	Applied
Decreasing	Bacteria	Levels
Episodic	Disinfection	AppliedEpisodic	Disinfection	Applied
Bacteria	Regrowth
Bacteria	Regrowth
Bacteria	Regrowth
Benefits	of	Continuous	+	Episodic
41
High
Low
Bacteria	Levels
Time
=	Continuous	+	Episodic
=	Continuous	Only
=	Episodic	Only
Benefit	from	
Continuous	+	
Episodic	vs.	
Episodic-Only		
Disinfection
Additional	Bacteria	
Removed
Episodic	vs.	Continuous
Episodic	(UV)
• Useful	in	outbreak	or	terminal	
cleaning	applications
• Often	takes	the	room	out	of	
service
• Potential	safety	issues
• Potential	compliance	issues
Continuous	(Visible)
• Useful	in	areas	which	must	
remain	operational	24/7
– Capacity	Limitations
– Quick	Turnover
• Cleans	even	when	people	
aren’t	in	the	room
• Designed	to	be	safe	for	
patients	and	staff
• Eliminates	compliance	issues
Which	is	Better?
Episodic	VS. Continuous Episodic	+ Continuous
CONTINUOUS	ENVIRONMENTAL	
DISINFECTION	USING	VISIBLE	LIGHT
44
What	is	Visible	Light	Disinfection?
Typical	UV-C	
Germicidal	
Wavelength
Visible	Light	Disinfection	
Germicidal	Wavelength	
(405nm)
What	is	Visible	Light	Disinfection?
• A	continuous	environmental	disinfection	system	which:
– Uses	safe,	visible light
– Can	be	integrated	into	normal,	overhead	lighting
46
Indigo-OnlyMixed-White
White	Disinfection	Mode	=	
Ambient	White	Light	+	Disinfection
Indigo	Disinfection	Mode	=	
Increased	Disinfection	Only
Types	of	Visible	Light	Disinfection
• Disinfection	only
47
• Indigo-Only • Mixed	White
• Use	of	complimentary	colors	
allows	for	ambient	lighting	
applications
How	Does	Visible	Light	Disinfection	Work?
48
3.	Pathogen	inactivation	breaks	the	
environmental	chain	of	infection
2.	Environment	creates	Reactive	Oxygen	Species	
within	bacteria	causing	inactivation
=
1.	Continuous,	automatic,	safe	system	creates	hostile	
environment	for	bacteria
4.	Measured	bacterial	reduction*
*Maclean	M.,	et.	al.		Environmental	decontamination	of	a	hospital	isolation	room	using	high-intensity	narrow-
spectrum	light,		J.	Hosp.	Infection	Vol.	76,	pp.	247-251	(2010)
Visible	Light	Disinfection	Safety
History	of	Academic	Research	&	Investment	in	
Visible	Light	Disinfection
Research	Timeline
More	than	30	
refereed	
publications	
and	
proceedings	
since	2008
Visible	Light	
Disinfection	
Commercially	
Available
Visible	Light	Disinfection In	An	Operating	
Room
51
Airborne	
Pathogens
Variety	of	Surfaces Hard	to	Reach
Why	Visible	Light	Disinfection	in	the	OR?
Visible	Light	Disinfection	Application:	
Operating	Rooms
• Ambient	lighting	levels	in	operating	rooms	are	
governed	by	IES	guidelines
53
Deploying	Visible	Light	Disinfection	in	the	OR
~625	sq.	ft. ~625	sq.	ft.
1:1	Replacement
~625	sq.	ft.
• Contact	manufacturer	to	ensure	proper	dosing	of	room	based	
on	1:1	replacement
Visible	Light	Disinfection	Operating	Room	
Solutions
55
2’x4’ 2’x2’ 1’x4’
Clinical	Implementation	of	Visible	Light	
Disinfection
• Wall	switch	can	be	used	to	select	desired	mode OR
• Occupancy/vacancy	sensor	can	automatically	switch	between	modes
56
Indigo-OnlyMixed	White
White	Disinfection	Mode	=
Ambient	White	Light	+	Disinfection
Indigo	Disinfection	Mode	=	
Increased	Disinfection	Only
Control	Solution(s)
• “Maximize	Dose	Without	Impacting	Visual	Acuity”
57
Passive	Infrared	Sensor	
detects	larger	motions	over	
a	larger	area
Ultrasonic	Sensor	detects	small	
motions	in	a	focused	area	
(over	the	table)
CURRENT	EVALUATION	DATA	FOR	
VISIBLE	LIGHT	DISINFECTION
58
ESKAPE Pathogens
• Enterococcus faecalis
• Staphylococcal Aureus*
(including MRSA)1
• Klebsiella pneumoniae
• Acinetobacter baumannii
• Pseudomonas aeruginosa
• Enterobacter species
Demonstrated	Laboratory	Susceptibility	to	Visible	
Light	Disinfection
Gram-Positive Bacteria
• Clostridium perfringens
• Staphylococcus epidermidis (CONS)
• Staphylococcus hyicus (CONS)
• Streptococcus pyogenes
• Listeria monocytogenes
• Mycobacterium terrae
• Corynebacterium striatum
Gram-Negative Bacteria
• Proteus vulgaris
• Escherichia coli (E. coli)
• Campylobacter jejuni
• Salmonella enteritidis
• Shigella sonnei
• Serratia spp
Yeast & Filamentous Fungi
• Aspergillus niger
• Candida albicans
• Saccharomyces cerevisiae
Bacterial Endospores
• Clostridium difficile
• Bacillus cereus
*=	Demonstrated	clinical	susceptibility	
to	presumptive	S.	Aureus &	MRSA
1Maclean	M.,	et.	al.		Environmental	decontamination	of	a	hospital	isolation	room	using	high-intensity	narrow-
spectrum	light,		J.	Hosp.	Infection	Vol.	76,	pp.	247-251	(2010)
Significant reduction of total bacterial contamination
on surfaces around the room (2-day use)
76%	
reduction
86%	reduction
All reductions in bacterial contamination were achieved over and above standard
cleaning and infection control practices
Whole Room Results Surface-Specific Results
Bacterial reduction on a range of surfaces before
and after use of the Visible Light Disinfection
Glasgow	Royal	Infirmary:	Intensive	Care	Unit	
(Initial	Studies)2
2Maclean	M.,	et.	al.	Continuous	decontamination	of	an	intensive	care	isolation	room	during	patient	occupancy	using	
405nm	light	technology.	Journal	of	Infection	Prevention,	14(5);	176- 181	(2013)
Lights	Off
Lights	On
Additional	Publication	Data
61
For	a	full	list	of	available	
publications,	please	visit:
http://www.indigo-clean.com/resources-
white-papers
Froedtert &	The	Medical	College	of	
Wisconsin	Froedtert Hospital
• GI	Diagnostic	Waiting	Area
– Easier	to	show	a	reduction	due	to	
high	amount	of	bacteria
– Proximity	to	procedure	rooms
– Approximately	450	ft.2 (Equivalent	
to	small	OR)
– Results	consistent	with	previously	
published	patient	room	results
– Additional	studies	underway
Clinical	Results	for	Visible	Light	Disinfection
• Inactivation	of	S.	aureus	in	Waiting	Room
63
70%+	Decrease
“In	Phase	2	of	the	
trial,	where	the	
lighting	deployment	
was	optimized	
across	the	room,	we	
were	able	to	
improve	the	
bacterial	reduction	
to	more	than	70%.”	
- Dr.	Nathan	
Ledeboer,	Associate	
Professor	of	
Pathology,	Medical	
College	of	
Wisconsin
Clinical	and Commercial	Deployment
• State-of-the-art	facilities	in	Las	
Vegas	
• Henderson	Hospital	and	Spring	
Valley	Hospital- Universal	Health	
Services	Inc.
64
Clinical	Results	from	ID	Week	2016
• 4 posters	covering:
– Visible	Light	Disinfection
– Improved	Environmental	
Hygiene	=	Reduced	HAI
65
Summary
• Visible	Light	Disinfection	provides	a	way	to	improve	
environmental	hygiene	that	compliments	current	
efforts
• It	is	safe,	contains	no	UV,	and	can	be	operated	while	
people	are	in	the	room
• It	can	be	integrated	with	overhead	lighting	and	
operated	automatically	without	the	need	for	
additional	people
• It	uses	reliable	LED	technology	to	increase	lifetime	
and	lower	ongoing	costs
This	concludes	The	American	Institute	of	Architects	
Continuing	Education	Systems	Course
Dr.	Clifford	J.	Yahnke
Director,	Clinical	Affairs
Indigo-Clean
cyahnke@kenall.com
(262)	891-9738

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