Overview over CIMT activities and structure

1. A ssociation for C ANCER IM MUNO T HERAPY (CIMT) 29. DEUTSCHER KREBSKONGRESS Berlin 24. – 27. Februar 2010 Individualisierte Immunintervention in der Tumormedizin www.cimt.eu

2. H.-G. Rammensee C. Huber G. Schuler P. Johnson C. Melief U. Kalinke P. Walden Executive Board CIMT – The People Scientific Secretaries Local Organizers C. Britten S. Kreiter T. Seppman M. Diken Scientific Advisory Board P. Beckhove P. Bossart U. Keilholz C. Ottensmeier G. Parmiani U. Sahin M. Schmitt J. Schultze H. Singh F. Stevenson T. Tüting T. Wölfel

4. CIMT – The Organigramm Executive Board Scientific advisory Board Scientific Secretaries Communications Director Annual Meting Regulatory Research Group CIMT Immunoguiding Program Patient Academy Local Organizers Adminstration

5. Annual Meetings CIMT – The Annual Meetings

7. Regulatory Research Group Chair: U. Kalinke Members: H. Singh, U. Sahin, J. Müller-Berghaus, T. Hinz, K.J. Kallen, C. Britten, S. Kreiter CIMT – Regulatory Research Group CVC Delegate A. Hoos Scientific Sessions Comments to Guidelines Co-operations Research Projects EMEA Comments and suggestions regarding the planned implementation of the “Advanced Therapy Medicinal Prodcuts „Regulation (EC) No 1394/2007 (7th July 2008) FDA Draft Guidance for Industry: Clinical Considerations for Therapeutic Cancer Vaccines (16 th Dec. 2009)

8. C. Gouttefangeas C. Britten S. Van der Burg (Current Chair) C. Ottensmeier M. Welters M. Kalos CIMT – Immunoguiding Program (CIP) Workshops + Scientific Sessions Co-operation with other groups Proficiency Panel Program Dissemination of Datav Services HLA-peptide Multimers ELISPOT Intracellular Cytokine Staining

10. Immune response Tumor size Patient survival time Treatment early late CIMT – Immunoguding Program (CIP) T cell Immunomonitoring Imaging Techniques Clinical Endpoints

11. Announced in Immunity: www.miataproject.org CIP – Minimal Information About T cell Assays First consensus workshop will take place in Washington on March 19th. Workshop is hosted by CRI-CVC and CIP.

13. CIMT – Partners and Sponsors