Presentation by Chris Young (Knowledgent) and Drew Holzapfel (CEOi) at BioIT World 2014 in Boston, MA.

1. ©2014 Knowledgent Group Inc. All Rights ReservedPlease stop by and see us at Booth #240!
Big Data Agenda to
Tackle Alzheimer’s

2. ©2014 Knowledgent Group Inc. All Rights ReservedPlease stop by and see us at Booth #240!
Normal
Brain
Alzheimer’s
Disease

3. ©2014 Knowledgent Group Inc. All Rights ReservedPlease stop by and see us at Booth #240!
“The consequences of dementia
for societies and economies are
devastating everywhere, in high-
income countries and low- and
middle-income countries alike...”
-The World Health
Organization

4. ©2014 Knowledgent Group Inc. All Rights ReservedPlease stop by and see us at Booth #240!
A public-private partnership
initiated by leading global
corporations and involving non-
profit and governmental
organizations to identify and
advance activities prevent and
treat Alzheimer's disease by 2025
and improve the quality of life for all
affected by the disease.

5. ©2014 Knowledgent Group Inc. All Rights ReservedPlease stop by and see us at Booth #240!
2014 Strategic Priorities
Drug
Development
Better, Faster, Ch
eaper
Financial
Resources
Increase and
innovate
Big Data
New insights to
drive change
Care Delivery
Addressing
today’s
challenges

6. ©2014 Knowledgent Group Inc. All Rights ReservedPlease stop by and see us at Booth #240!
• Expose untapped correlations & insights
between massive existing & emerging data sets
(Causes, Treatments, Care Delivery
Improvements)
• Break down barriers and enable analysis of
information generated across industries
(Healthcare, Payers, Labs, Pharma, Gov’t, and
The Big Data Opportunity
EHR Claims Imaging Genomic Trials Behavioral
Exponentially increasing amount of information
Devices

7. ©2014 Knowledgent Group Inc. All Rights ReservedPlease stop by and see us at Booth #240!
Insights may identify early detection
signals, root causes, or new drug targets
through:
 Genomic Similarities
 Longitudinal Patient Patterns
 Brain Imaging Analysis
 Comorbidity Recognition
 Behavioral/Lifestyle Influence
 Demographical Dimensionality
 Correlations Across Patterns
 Generate Additional Hypotheses
Big Data Supporting Research Analytics

8. ©2014 Knowledgent Group Inc. All Rights ReservedPlease stop by and see us at Booth #240!
We have a poster size version of Knowledgent’s 2014 Big Data Ecosystem for you to dive into!
Aligning Tech with the Analytical Use
Case

9. ©2014 Knowledgent Group Inc. All Rights ReservedPlease stop by and see us at Booth #240!
Actions Towards Big Data Agenda
Planning &
Execution of
Big Data
Initiatives
Member &
Partner
Engagement
Global
Awareness &
Socialization
• CEOi
Summit, NIH, OECD, G7,
Webinars…
CEOi
Member
Strategy
Session
Bio-IT World
& Launch of
Big Data Strategy
Paper Series

10. ©2014 Knowledgent Group Inc. All Rights ReservedPlease stop by and see us at Booth #240!
“Global leadership and collaboration
across business and government are
essential to drive coordinated
action, promote rapid innovation and
spur the focus needed to achieve a
means of prevention and effective
diagnosis, treatment and care for
Alzheimer’s and dementia. Join us.”
- George Vradenburg
Convener, CEOi

11. ©2014 Knowledgent Group Inc. All Rights ReservedPlease stop by and see us at Booth #240!
Drew Holzapfel
Executive Director
drew@ceoalzheimersinitiative.org
+1 703 599 9617
ceoalzheimersinitiative.org
Chris Young
Life Sciences Partner
chris.young@knowledgent.com
+1 732 690 1457
knowledgent.com
Our Strategy Paper Series can be found on both the
CEOi & Knowledgent Websites