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PELVIC
CONGESTION
SYNDROMEDr. Junish Singh Bagga
INTRODUCTION
➤ Females of childbearing age.
➤ 1949 - Taylor
➤ 15% pelvic pain - 10% PCS
➤ D/D of PCS
➤ Endometriosis
➤ Uterine fibroma
➤ Pelvic malignancy/SOL
➤ Pudendal nerve compression
ANATOMY
➤ Internal iliac vein
parietal branches - superior,
inferior gluteal, sciatic, sacral,
ascending lumbar, obturator
visceral - internal pudendal,
middle hemorrhoidal,
vesicoprostatic/uterine,
gonadal, vesicovaginal
➤ Gonadal veins
utero-ovarian, salpingo-
ovarian (broad ligament)
INTERNAL ILIAC -
UTERO-OVARIAN
1. Ovarian vein
2. Internal iliac vein
3. Uterine vein
4. Obturator vein
5. External pudendal vein
6. Great saphenous vein
7. Antero-medial thigh varicosity
8. Postero-lateral thigh varicosity
9. Sciatic vein
10.Vulvar varicosity
11.Internal pudendal vein
12.Cystic, vaginal veins
13.Buttock veins
VALVES IN
GONADAL VEINS
Males – upto 40% gonadal veins are devoid of valves
Females – left 13% no valves
right 6%
PATHOPHYSIOLOGY
➤ Type 1 -
Vein incompetence.
?hormonal
estradiol - inhibits reflex
vasoconstriction
➤ Type 2 -
Outflow obstruction
MTS, renal vein thrombus,
Budd-chiari
➤ Type 3 -
Local factors
endometriosis, trauma,
tumors, infections
CLINICAL FINDINGS
➤ 20-30 year females, multiparous
➤ Disappear after menopause
➤ Rare in men, varicocele, obstructive
pathology
➤ Symptoms
chronic pelvic pain, heaviness, dyspareunia,
dysmenorrhoea, urinary and rectal
symptoms.
relieved on supine position.
➤ Mostly on one side, may be bilateral.
➤ Lower limb symptoms
superficial venous insufficiency, recurrent
varicosity.
atypical varicose veins (buttock, posterior
and lateral aspect of thigh)
DUPLEX SCAN
➤ 5 Mhz
➤ Internal iliac + gonadal
veins
➤ Varicosity with venous
doppler signals
➤ > 5mm
➤ Obturator, sciatic, internal
pudendal
➤ Common iliac, IVC, renal
veins
➤ Lower extremity - optional
CT VENOGRAPHY
➤ CT Venography - indirect
venography (recirculation)
100-150cc contrast (2ml/kg)
➤ Veins above > 80 HU - diagnostic
➤ Timing is tricky - limiting factor
60 sec - thoracic
70-80 sec - upper extremity
11 sec - pelvis
150-180 sec for lower extremity
➤ Opacification in the arterial phase
➤ Diameter > 7mm
MR VENOGRAPHY
➤ T2 weighted, gradient echo MRI
➤ T1 weighted gradient echo with
gadolinium are most effective for
diagnosing pelvic varicosity.
Negatives
Expensive, availability sometimes
limited
Exam may be lengthy
Pt. cooperation
Spatial resolution (vs other
choices)
Limited anatomic coverage
CONTRAST PHLEBOGRAPHY
➤ Gold standard
➤ Femoral, brachial approach
➤ Both internal iliac, both gonadal
➤ Ovarian vein valvular
incompetence
➤ >5mm
➤ 20 sec contrast hold
➤ Congestion in pelvic venous
plexus
➤ Opacification of internal iliac
vein
➤ Filling of vulvo-vaginal, thigh
varicosity
MEDICAL MANAGEMENT
➤ Medroxyprogesterone
acetate 30mg/day x 6
months
50% improvement in
73% patients
➤ Goserelin acetate
3.6mg/month x 6 months
➤ MPFF 500mg twice daily
for 6 months
CONVENTIONAL & LAPAROSCOPIC
SURGERY➤ Hysterectomy + b/l
salpingo-
oophorectomy
➤ Ovarian and/or
internal iliac vein
ligation
➤ Uterine artery and
vein ligation
➤ Oophorectomy
ENDOVASCULAR
➤ Basic Principles
➤ Entire internal iliac vein shouldn’t be embolized
➤ Gonadal vein embolisation to be performed proximal to last collateral
HARDWARE / INSTRUMENTS
➤ Femoral vein cannulation 5f, 6f
➤ Multi-purpose catheter, Simmon’s catheter(acute angle),
Cobra-2 (60-120)
EMBOLIZATION AGENTS
➤ Coils - 0.035 inch
for 4f or 5f cath
0.018 inch -
microcatheters
➤ Vascular plugs -
Amplatzer
➤ Foam sclero can
be added before
coiling or sandwich
➤ Glue -
cyanoacrylate
➤ Internal iliac vein
balloon
COMPLICATIONS
➤ Hematoma, access
site complications
➤ Extravasation of
contrast
➤ Coil or glue
embolisation
➤ DVT, PE
➤ Transient cardiac
arrhythmia
Pelvic Congestion Syndrome

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Pelvic Congestion Syndrome

  • 2. INTRODUCTION ➤ Females of childbearing age. ➤ 1949 - Taylor ➤ 15% pelvic pain - 10% PCS ➤ D/D of PCS ➤ Endometriosis ➤ Uterine fibroma ➤ Pelvic malignancy/SOL ➤ Pudendal nerve compression
  • 3. ANATOMY ➤ Internal iliac vein parietal branches - superior, inferior gluteal, sciatic, sacral, ascending lumbar, obturator visceral - internal pudendal, middle hemorrhoidal, vesicoprostatic/uterine, gonadal, vesicovaginal ➤ Gonadal veins utero-ovarian, salpingo- ovarian (broad ligament)
  • 4. INTERNAL ILIAC - UTERO-OVARIAN 1. Ovarian vein 2. Internal iliac vein 3. Uterine vein 4. Obturator vein 5. External pudendal vein 6. Great saphenous vein 7. Antero-medial thigh varicosity 8. Postero-lateral thigh varicosity 9. Sciatic vein 10.Vulvar varicosity 11.Internal pudendal vein 12.Cystic, vaginal veins 13.Buttock veins
  • 5. VALVES IN GONADAL VEINS Males – upto 40% gonadal veins are devoid of valves Females – left 13% no valves right 6%
  • 6. PATHOPHYSIOLOGY ➤ Type 1 - Vein incompetence. ?hormonal estradiol - inhibits reflex vasoconstriction ➤ Type 2 - Outflow obstruction MTS, renal vein thrombus, Budd-chiari ➤ Type 3 - Local factors endometriosis, trauma, tumors, infections
  • 7. CLINICAL FINDINGS ➤ 20-30 year females, multiparous ➤ Disappear after menopause ➤ Rare in men, varicocele, obstructive pathology ➤ Symptoms chronic pelvic pain, heaviness, dyspareunia, dysmenorrhoea, urinary and rectal symptoms. relieved on supine position. ➤ Mostly on one side, may be bilateral. ➤ Lower limb symptoms superficial venous insufficiency, recurrent varicosity. atypical varicose veins (buttock, posterior and lateral aspect of thigh)
  • 8. DUPLEX SCAN ➤ 5 Mhz ➤ Internal iliac + gonadal veins ➤ Varicosity with venous doppler signals ➤ > 5mm ➤ Obturator, sciatic, internal pudendal ➤ Common iliac, IVC, renal veins ➤ Lower extremity - optional
  • 9.
  • 10. CT VENOGRAPHY ➤ CT Venography - indirect venography (recirculation) 100-150cc contrast (2ml/kg) ➤ Veins above > 80 HU - diagnostic ➤ Timing is tricky - limiting factor 60 sec - thoracic 70-80 sec - upper extremity 11 sec - pelvis 150-180 sec for lower extremity ➤ Opacification in the arterial phase ➤ Diameter > 7mm
  • 11. MR VENOGRAPHY ➤ T2 weighted, gradient echo MRI ➤ T1 weighted gradient echo with gadolinium are most effective for diagnosing pelvic varicosity. Negatives Expensive, availability sometimes limited Exam may be lengthy Pt. cooperation Spatial resolution (vs other choices) Limited anatomic coverage
  • 12. CONTRAST PHLEBOGRAPHY ➤ Gold standard ➤ Femoral, brachial approach ➤ Both internal iliac, both gonadal ➤ Ovarian vein valvular incompetence ➤ >5mm ➤ 20 sec contrast hold ➤ Congestion in pelvic venous plexus ➤ Opacification of internal iliac vein ➤ Filling of vulvo-vaginal, thigh varicosity
  • 13. MEDICAL MANAGEMENT ➤ Medroxyprogesterone acetate 30mg/day x 6 months 50% improvement in 73% patients ➤ Goserelin acetate 3.6mg/month x 6 months ➤ MPFF 500mg twice daily for 6 months
  • 14. CONVENTIONAL & LAPAROSCOPIC SURGERY➤ Hysterectomy + b/l salpingo- oophorectomy ➤ Ovarian and/or internal iliac vein ligation ➤ Uterine artery and vein ligation ➤ Oophorectomy
  • 15. ENDOVASCULAR ➤ Basic Principles ➤ Entire internal iliac vein shouldn’t be embolized ➤ Gonadal vein embolisation to be performed proximal to last collateral
  • 16. HARDWARE / INSTRUMENTS ➤ Femoral vein cannulation 5f, 6f ➤ Multi-purpose catheter, Simmon’s catheter(acute angle), Cobra-2 (60-120)
  • 17. EMBOLIZATION AGENTS ➤ Coils - 0.035 inch for 4f or 5f cath 0.018 inch - microcatheters ➤ Vascular plugs - Amplatzer ➤ Foam sclero can be added before coiling or sandwich ➤ Glue - cyanoacrylate ➤ Internal iliac vein balloon
  • 18. COMPLICATIONS ➤ Hematoma, access site complications ➤ Extravasation of contrast ➤ Coil or glue embolisation ➤ DVT, PE ➤ Transient cardiac arrhythmia