This document provides a summary of recent advances in neuroscience, including new techniques such as optogenetics, which uses light to control neural activity, expansion microscopy to view fine neural structures, and CLARITY to render tissues transparent. It discusses efforts to map structural and functional brain networks, characterize different cell types, and model the worm Caenorhabditis elegans nervous system. The document also covers decoding neural representations, reconstructing images from brain activity, and applications like brain-to-brain communication and potential for lie detection with fMRI.
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Superfluous Neuroscience
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5.
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Transsynaptic Tracing
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Expansion Microscopy
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CLARITY
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CLARITY
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Golgi Stain
Brainbow
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20. Optogenetic actuators
(e.g. channelrhodopsin)
Optogenetic sensors
(e.g. Clomeleon, Mermaid)
Genetic Construct
inserted into virus
Virus is injected
into animal
Laser light is used to
Control activity of infected
neurons
Activity of infected
neurons is measured via
optic sensor
Optogenetics
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Image: Evan Wondolowski of Collective Next
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“Closed Loop” Optogenetics
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Brain-to-Brain Communication
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OpenWorm
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Robot Worms
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The Human Connectome
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The Face Processing Network
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The Default Mode Network
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Multi-Voxel Patten Analysis
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Multi-Voxel
Patten Analysis
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Neural Decoding with MVPA
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44. fMRI and Lie Detection?
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