pharmaceutical packaging material for the different dosage form conventional, sterile,ophthalmic, transdermal, dosage forms.

1. Presented By
Mr. Mitkari Jayshankar V.
M. Pharm.
( Pharmaceutics Department )
Under the guidance
Of
Mrs. Bidkar S. J.
Sharadchandra Pawar college of Pharmacy, Otur, Pune.
Pharmaceutical Packaging Materials

2. INTRODUCTION
 Packaging is the science, art and technology of enclosing
or protecting products for distribution, storage, sale, and
use.
 Pharmaceutical packaging can be defined as the
economical means of providing presentation, protection,
identification , information, convenience ,compliance ,
integrity and stability of the product .
2

3. FUNCTIONS OF PACKAGING
• Product Identification
• Product Protection
• Facilitating the use of product
• Product Promotion
3

4. TYPES OF PACKAGING
 Primary packaging-
Is the material that first envelops the product and hold it.
Ex. Aerosol spray can, blister packs, bottle
4

5.  Secondary packaging -
Is outside the primary packaging
Ex. Boxes, cartons
5

6.  Tertiary packaging-
Is used to bulk handling and shipping.
Ex. Barrel, container, edge protector
6

7. SOLID DOSAGE FORM (TABLETS,
CAPSULES, POWDERS)
Glass Bottles
• type III glass and NP glass is used.
• Transparent and Amber coloured glass
bottle
Plastic Bottle :
• Bottles made from polyethylene,
Polypropylene , Polystyrene.
• It is light weighted and non breakable.
7

8.  Blister packaging:
Forming cavity or pocket Polyvinyl chloride (PVC).
Backing membrane seal of aluminum foil
8

9.  Strip Packaging
Strip packs for a unit dosage.
Made from cellulose, paper, plastic, foil or
combination of these
The use of high barrier material like aluminum foil
or saran-coated film with excellent seal formation
for moisture-sensitive products.
9

10.  Pouches
 Plastic Pouches :
With a re-sealable strip at the top,
easy to open and close
It have Waterproof, tide proof, air
proof and non-poisonous property .
 Aluminum pouches :
1. It have tear strip facility
2. It offers excellent barrier properties to
the moisture, gas and light
Plastic Pouches
Aluminium pouches
10

11. Solids-Rectal (Suppository) :
1) Aluminum Foil
 Offers the highest possible protection against
moisture, oxygen, and light,.
 The aluminum suppository package takes the shape
of individual doses .
11

12. 2) Laminates for suppositories :
• It is made of Polyolefine,
Aluminum, P.E. .
• It gives protection from moisture,
gas ,vapors, light
12

13.  Solids (Inhalation) Dry-Powder Inhaler :
• It is made of plastics such as polyethylene (HDPE), Polypropylene ,
polystyrene .
13

14. LIQUID DOSAGE FORM
- Glass Or Plastic Bottle
- Bottle With Spray Pump
Capacity: 50ml
Material: Bottle-polyethylene terephthalate;
Sprayer-polypropylene
Spray output: 0.05ml-0.20ml
Used for body spray, oral spray, anti-bacterial spray.
14

15. Bottle With Dropper Assembly:
• Dropper assemblies can be supplied
with
coloured caps
• glass type II is used
• Dropper glass is of Sodalime glass(type
III) and Neutral glass(type I).
• Bottle capacity is from 2 to 100ml
• pipettes are up to 120mm in length
15

16. Aerosol spray :
Container: To withstand pressure 140-180 psi
1) Tin plate container- it is sheet of steel plates electroplated on both side with tin
2) Aluminum container- it has seamless nature and greater resistance to corrosion
3)Stainless steel container –used inhalation aerosol
4)Glass container – type I glass is used
16

17. STERILE PRODUCTS
 Glass Ampoules :
• Type I (borosilicate glass is used)
• Up to 3 colour can be placed for identification purpose.
• PVC mono films used for 20 packaging.
17

18. Vial With Stopper :
• Vials are mainly used for multiple dose
parenteral preparation and are provided with
the closure followed by aluminum seal to
ensure the perfect air tight packing
Closure:
• Made from Butyl rubber ,Nitrile rubbers ,Neoprene, Silicon
rubbers.
18

19. - Pre-Filled Syringe:
• It is used for small volume parenteral
preparation.
• Reduction of medication errors like drug
overfill.
• It gives Increased assurance of sterility
19

20. Sterile plastic devices :
Irrigation solution container :
• It is made of Polyolefin , polypropylenes
• It is light in weight, transparent, impermeable to
water
• Material have high boiling point so that it is
sterilizable .
20

21. OPHTHALMIC DOSAGE FORM
1) Plastic bottles:
• Material used for plastic bottle is
low density polyethylene,
• for caps are harder plastic materials
such HighdensityP.E. or Polypropelene is used.
2) Collapsible Tube
3) blow-Fill-Seal Plastic Bottle
21

22. Pouching Materials
There are three main layers in the composite materials
used for pouches:
1) Internal plastic heat sealable layer, -
material used -polyethylene, surlyn
2) Aluminium foil layer –
Its important role in protecting the product
from light and oxygen.
3) External printable layer.
It is used to achieve a better 'finishing' and
printing quality
material- Paper or polyester film is used
22

23. Opti-nose device :
• In this , air is blown out of the container and
sealing nozzle is used its direct flow of air in
nose
• It gives bi-directional flow so that it prevents
deposition of drug in lungs.
23

24. Direct-haler device :
for turbulent
dispersion of dose
for moisture protection
Transparenc
y of divice for
drug visibility
24

25. REFERENCE
 Lachman, Libarman; “The theory and practice of industrial
pharmacy”, third edition, varghese publishing house
 Jain U.K., Nayak S.; “Pharmaceutical packaging technology”
PharmaMed Press
 Dean D.A., Hall I.H.; “Pharmaceutical packaging technology”
Taylor and Francis
 Hanlon F. J., “Handbook of package engineering”, second
edition, Technomic Publishing CO. ING
25

26. “ THANK –YOU”
All