24. Minimal to Moderate
Signs (cont.):
Elevated BP Sweating
Elevated heart rate Nausea/vomiting
Elevated resp. rate Disorientation
Failure to follow commands / reason
Lack of response to painful stimuli
26. Minimal to Moderate
Symptoms (cont.):
Light-headed and dizzy
Drowsy and disoriented
Losing consciousness
Sensation of twitching (before actual
twitching is observed)
27. Moderate to High
Generalized tonic-clonic seizure activity
followed by
Generalized CNS depression
Depressed BP, heart rate
Depressed respiratory rate
31. Mild Reaction -slow onset
Reassure patient
Administer O2
Monitor vital signs
Consider IV anticonvulsant
Allow recovery or get medical help prn
Get medical consultation, esp. if possibility
of metabolic or renal dysfunction
32. Severe Reaction - rapid onset
Stop all treatment
Place patient in supine position, feet up
Establish airway, give O2 (BLS)
If convulsions, protect patient
Summon emergency medical help
Consider anticonvulsant drugs, vasopressors
33. Severe Reaction - slow onset
Stop all treatment
Establish airway, give O2 (BLS)
Administer anticonvulsant
Summon emergency medical help
Consider vasopressors
Get medical consultation, esp. if possibility
of metabolic or renal dysfunction
37. Management - v/c overdose
Stop dental treatment
Sit patient up
Reassure patient, administer O2
Monitor BP and pulse until fully recovered
38. Allergic Reactions
Type Mechanism Time Clinical Example
I Antigen induc. sec/min Angioedema,
Anaphylaxis
IV Cell mediated 48 hrs Contact
dermatitis
39. Allergens in Local
Esters - usually to the Para-amino-
benzoic-acid product
Na bisulfite or metabisulfite - found in
anesthetics as perservative for
vasoconstrictors
Methylparaben - no longer used as
perservative in dental cartridges
40. Management of Allergy Pts.
If the patient gives a history of allergy to
local anesthetics - Assume that an
allergy exists
Elective procedures
Postpone until work-up is completed
41. Management of Allergy Pts.
Emergency treatment
Protocol #1 - no invasive treatment ( I&D,
analgesics, antibiotics)
Protocol #2 - use general anesthesia
Protocol #3 - Histamine blocker (Benadryl)
Protocol #4 - Others: electronic dental
anesthesia, hypnosis, adjunctive N2O
45. Management of Reactions
Delayed skin reaction
Benadryl - 50 mg stat & Q6H X 3-4 days
Immediate skin reaction
Epinephrine 0.3 mg IM or SC
Benadryl - 50 mg IM
Observation, medical consultation
Benadryl - 50 mg Q6H X 3-4 days
46. Management of Reactions
Bronchial constriction
Semi-erect position, O2 - 6 L/min
Inhaler or Epinephrine 0.3 mg IM or SC
Benadryl - 50 mg IM
Observation, medical consultation
Benadryl - 50 mg Q6H X 3-4 days
47. Mangement of Reactions
Laryngeal edema
Place supine, O2 - 6 L/min
Epinephrine 0.3 mg IM or SC
Maintain airway
Benadryl - 50 mg IV or IM
Hydrocortisone - 100 mg IV or IM
Perform Cricothyrotomy
48. Management of Reactions
Anaphylaxis
Place supine, on flat surface
ABCs of CPR, call for medical help
Epinephrine 0.3 mg IV or IM (Q 5 mins)
O2 - 6 L/min, monitor vital signs
After clinical improvement,
Benadryl and Hydrocortisone
51. Prior to Treatment
Complete review of medical status
(including vital signs)
Anxiety / Fear should be assessed and
managed before administering anesthetic
52. Administration of Anesthetic
Place pt. supine or semi-supine position
Dry site, apply topical X 1 min
Select appropriate drug for treatment (time)
Vasoconstrictor unless contraindicated
53. Administration (cont.)
Weakest anesthetic in the minimum volume
(compatible with successful anesthesia)
Inject slowly (minimum of 60 sec / 1.8 ml)
Continually observe -
Never leave patient alone after injection
54. Administration (cont.)
Use only aspirating syringe
Aspirate in two planes, before injecting
Use sharp, disposable needles of adequate
diameter and length
57. LOCAL COMPLICATION OF
LOCAL ANESTHESIA
1. Complications arising from drugs or
chemicals used for local anesthesia
2. Complications arising from injection
techniques
3. Complications arising from both
58. Complications arising from drugs or
chemicals used for local anesthesia
1. Soft tissue injury
2. Sloughing of tissues (Tissue
ischemia and necrosis)
59. SOFT TISSUE INJURY
■ Causes
1. It is seen in the form
of self-inflicted
trauma to lips,
tongue and cheek
2. It is common in
children and mentally
retarded adults
ikassem@dr.com
60. 2- Sloughing of Tissues
(Tissue Ischemia and Necrosis)
Causes
1. predisposition: Commonly
in hard palate, as in the
region of distribution of
nasopalatine and greater
palatine nerves, because
mucoperiosteum is firmly
attached to the bone.
2. Deposition of excessive
volume of local anesthetic
agent with high
concentration of
vasoconstrictors
3. Rapid deposition of the
local anesthetic solution
with undue pressure
4. Application of topical
local anesthetic agent for
prolonged period
(epithelial desquamation)
62. COMPLICATIONS ARISING FROM
INJECTION TECHNIQUES
1. Breakage of anesthetic cartridge
2. Breakage of needle
3. Needle-stick injuries
4. Hematoma
5. Failure to obtain local anesthesia
ikassem@dr.com
63. Breakage of Anesthetic Cartridge
■ Causes
It occurs when there is
resistance to flow of
local anesthetic solution
in to the tissues
It occurs due to
following reasons:
1. Blockage of the needle
2. Too rapid injection;
especially during
administration of
palatal injection.
64. Breakage of Needle
■ Its very rare since the
introduction of sterile,
stainless steel
disposable needles
■ Causes :
Primary cause: Sudden
unexpected
movements by the
patient
65.
66. Needle-stick Injuries
■ It’s an accidental injuries
occurring to dental staff caused by sharp
instruments such as needles, blades, scalpels,
explorers, root canal instruments, and wires, etc
■ These injuries are not usually serious, unless,
the instruments used were contaminated by
blood from patients with conditions such as
Hepatitis B virus HBV Infection, Hepatitis C virus
HCV Infection, A IDS
67. Failure to Obtain Local Anesthesia
■ Causes
1. OPERATOR-DEPENDENT
II. Selection of local anesthetic agent (type and dose;
too small a dose)
III. Use of a local anesthetic solution which has
crossed its date of expiry
IV. Improper injection technique:
a. Wrong technique: Inaccurate placement of
solution
b. Not waiting long enough for anesthesia to act;
before commencing the surgery
IV. Intravascular administration
V. Intramuscular administration
68. 2- PATIENT - DEPENDENT
I. Anatomical:
b. Barriers to diffusion
c. Anatomical aberrations
d. Additional innervations
II. Psychological:
Fear and apprehension : unco-operative
patient, inadequate opening of the
mouth, movement by the patient
70. PAIN ON INJECTION
■ This increases patient’s anxiety;
and may lead to a sudden unexpected
movement by the patient and increases
the risk of needle breakage.
■ Management
Not required. However, steps should be
taken to avoid pain associated with
injection of local anesthetic agent
71. PAIN ON INJECTION
■ Causes
1. Careless injection technique
2. Dull needles
3. Rapid deposition of local anesthetic solution
4. Needles with barbs: There is pain while
withdrawal of the needle from the tissues
5. Temperature: Extremes of temperature
such as warm or hot or very cold
(refrigerated) local anesthetic solution
72. TRISMUS
■ Trismus is the inability to normally open
the mouth
■ It is a fairly common complication of local
anesthesia, particularly while giving
pterygomandibular block
73. MUCOSAL BLANCHING
■ It is caused by the spasm of the artery
accompanying
the nerve at the point of injection
Causes
1. Use of excessive amount of vasoconstrictor
2. Deposition of excessive volume of local
anesthetic solution in firm or tight tissue
74. PERSISTENT ANESTHESIA OR
PARESTHESIA (NERVE INJURIES)
■ Persistent paresthesia can lead to self-inflicted
injury. Biting, or thermal or chemical insults can
occur without the patients awareness
■ The condition is more frequent as a result of
operative procedure than injection itself
■ The sensory nerves most frequently traumatized
are inferior alveolar nerve, lingual nerve, and
mental nerves in lower jaw; and infraorbital nerve
in upper jaw
75. POST-INJECTION HERPETIC LESIONS OR
POST-ANESTHETIC INTRAORAL LESIONS
■ Patients’ reporting of
development of ulcerations
around the site of injection a
few days after intraoral injection
of local anesthetic agent. Patient
complains of intense pain
■ Cause
❑ Recurrent Aphthus Stomatitis
(RAS): It is a frequent
manifestation, developing in
gingival tissues (movable part,
i.e. not attached to the bone)
76.
77. FACIAL NERVE PARALYSIS
■ Paralysis of some of the muscles
of facial expression which are
supplied by some of the terminal
branches of facial nerve, when the
solution is deposited in their
vicinity