Experts discuss the fundamentals of real-time, beat-to-beat noninvasive blood pressure (NIBP) monitoring and present new research capabilities enabled through the integration of NIBP technology and physiological recording systems. In this webinar sponsored by BIOPAC Systems and CNSystems, Frazer Findlay and Walter Habenbacher discuss study design and demonstrate correct equipment set up and operation when recording NIBP with additional physiological signals. Specifically, Mr. Habenbacher explains the application of the NIBP100D-HD to measure noninvasive continuous blood pressure. He demonstrates setup & measurement and shows how scientific findings can benefit your research with advanced hemodynamic monitoring. Following, Mr. Findlay demonstrates how to interface the NIBP100D Continuous Noninvasive Blood Pressure Monitor with the BIOPAC MP160 Data Acquisition and Analysis System and simultaneously recorded measurements of NIBP, ECG and respiration. In addition, Mr. Findlay discusses important data analysis processes such as computing cardiac output and stroke volume, and demonstrates how scientists can use the “Focus Areas” feature in AcqKnowledge Software to simplify their data review.

1. Integrating Noninvasive Blood
Pressure Monitoring with Human
Physiology Measurements
Experts discuss the fundamentals of real-time, beat-to-beat
noninvasive blood pressure (NIBP) monitoring and present new
research capabilities enabled through the integration of NIBP
technology and physiological recording systems.

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3. Walter Habenbacher
Head of Sales & Marketing,
CNSystems Medizintechnik AG
NIBP100D-HD Hemodynamic
Monitoring @ Your Fingertips
© CNSystems Medizintechnik AG. 2016
www.cnsystems.com

4. www.cnsystems.com
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MOVING FROM SNAPSHOTS… …TO CONTINUOUS INFORMATION
NBP CNAP®

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Hemodynamic monitoring @ your fingertips
NIBP100D-HD – CONTINUOUS & NONINVASIVE
* CE approved / FDA pending.
Blood Pressure
Cardiac Output & Stroke Volume*
Systemic Vascular Resistance*
Pulse Rate
[click to learn more]

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SETUP & CALIBRATION
click to watch the videos
[advance to 06:08]

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CNAP® TECHNOLOGY – HOW IT WORKS
IR light picks up blood volume and flow1
2
In- and deflating pressure cuff follows pulsation and keeps
blood flow constant 1
3 High accuracy thru calibration with NBP 2
2
IR light
1
Sys
Dia
Mean
3
1 Jan Penaz, Brno, Czech Republic 1973
2 Fortin J et al.: Continuous noninvasive BP monitoring using concentrically interlocking control loops. Comput in Biol Med 36 (2006)

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CNAP® TECHNOLOGY – HOW IT WORKS
click to watch the video
[advance to 10:05]

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SETTING UP MEASUREMENTS IS EASY
 Measurement settings
measurement
30min
setup
5min
buffer
5min
 Total time: ≈ 40min
 Set CNAP Cal Interval to 40min (switch between fingers)
 Set NBP Interval to 40min (calibration to upper arm)

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PROVEN TECHNOLOGY OVER DECADES
http://www.cnsystems.com/literature
Task Force® Monitor
NIBP100D
Over 500 peer reviewed publications reflect the trust
in the accuracy and utility in research & clinical settings

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PERFORMANCE DURING VALSALVA
Initial BP rise
Impeded venous return (fall in BP)
Compensation (pulse rate & vasoconstriction)
Pressure release
Overshoot (return of CO)
1
2a
3
4
2b
40
50
60
70
80
90
100
0 10 20 30 40 50 60 70 80
BloodPressure[mmHg]
VALSALVA 1 2a 2b 3 4

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PERFORMANCE DURING VALSALVA
click to watch the video
[advance to 14:36]

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THE ROLE OF CARDIAC OUPUT & VASCULAR RESISTANCE
Blood pressure
Resistant
Blood flow
MABP = HR x SV x SVR
The Ohm´s law applied to physiology

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1 Kirby, L. D., & Wright, R. A. (2003). Cardiovascular correlates of challenge and threat appraisals: A critical examination of the Biopsychosocial Analysis. Personality and Social Psychology Bulletin,7, 216-233.
2 Tomaka, J., Blascovich, J., Kelsey, R. M., & Leitten, C. L. (1993). Subjective, physiological, and behavioral effects of threat and challenge appraisal. Journal of Personality and Social Psychology,65, 248-260.
3 Lackner, H. K., Weiss, E. M., Schulter, G., Hinghofer-Szalkay, H., Samson, A. C., & Papousek, I. (2013). I got it! Transient Cardiovascular Response to the Perception of Humor. BiologicalPsychology, 93, 33–40.
BLOOD PRESSURE, CARDIAC OUTPUT AND VASCULAR RESISTANCE
ARE IMPORTANT CV CORRELATES OF CHALLENGE & THREAT

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HEMODYNAMIC MONITORING @ YOUR FINGERTIPS:
CONTINUOUS & NONINVASIVE
Calibrated blood pressure &
hemodynamics
Up & running in 1.5 minutes
Quick set up of measurement
Reliable short and longterm
monitoring
Easy integration
(MP150 / 160)

16. Frazer Findlay CEO, BIOPAC Systems, Inc.
Integrating NIBP with Human
Physiology Measurements
BIOPAC—Inspiring people and enabling discovery about life
© BIOPAC Systems, Inc. 2016
www.biopac.com

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Over 97% of top universities run BIOPAC Systems
THE WORLD DISCOVERS
WITH BIOPAC
Solutions for life science research and education

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Combining Noninvasive Blood Pressure with other
Physiological Signals
BioNomadix
Wireless
Physiological
Data
Mobita System
32-Channel EEG
/ Biopotentials
B-Alert System
9-Channels of EEG
and Cognitive
States Metrics
MP36R System
4-Universal
Channels
MP160 System
16-Channels of
Tethered or
Wireless Signals

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Stimulus Presentation with
Triggers for Synchronization
SuperLab® - E-Prime®
Presentation®
Virtual Reality
BIOPAC VR Solutions
offer real-time feedback
loops and event
marking

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Stationary Eye Tracking
with Visual Stimulation
Unrestrained Mobile
Eye Tracking

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Hardware Communication NIBP100D
Continuous Noninvasive
Blood Pressure System
DA100C with TCI105
MP160 System
16-Channel Data
Acquisition
System

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Hardware Communication
CBLNIBP100D-HD
HLT100C and 4 x
INISO Isolation
Adapters
NIBP100D-HD
Continuous Noninvasive
Blood Pressure System with
Hemodynamics
HemodynamicMeasurement
Cardiac Output (CO), Stroke Volume (SV), Pulse Pressure Variation (PPV),Stroke Volume Variation (SVV),Systemic Vascular
Resistance(SVR)
MP160 System
16-Channel Data
Acquisition
System

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Hardware Communication with Visual Stimulus
Stimulus is delivered to subject at a
stationary monitor or by VR...
SuperLab
E-Prime
Vizard
Presentation
Front
FrontBack
STP100C

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Hardware Communication with Visual Stimulus
Stimulus is delivered to subject at a
stationary monitor or by VR...
Front
FrontBack
STP100C

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Hardware Communication with Visual Stimulus
Stimulus is delivered to subject at a
stationary monitor or by VR...
Triggers sent to the
MP160 System
Front
FrontBack
STP100C

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AcqKnowledge Automated Analysis Software
• Arterial Blood Pressure
Analysis
• Estimate Cardiac Output
from Arterial Blood
Pressure
• Baroreflex Sequence
Analysis
• Baroreflex Slope Analysis

28. Demonstration of AcqKnowledge Software
[click to watch the demonstration – advance to 31:11]

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• Combine Noninvasive Blood Pressure with a wide variety of
signals
• Interface with stimulus presentation systems such as E-Prime,
SuperLab, Presentation and BIOPAC Virtual Reality systems
• Monitor subject eye position, gaze path and facial expressions
• Maintain synchronization across devices
Summary

30. Walter Habenbacher
office@cnsystems.com
Frazer Findlay
info@biopac.com
For additional information on the products and applications presented during
this webinar please visit www.cnsystems.com and www.biopac.com
Thank You