1. The document outlines an animal health component that focuses on developing vaccines, diagnostics, and biosecurity protocols for infectious diseases through two interdependent activities: value chain assessments and current projects using generic platforms. 2. Key outputs by 2012-2013 include improved diagnostics and vaccines for diseases like East Coast fever, CBPP, and ASF, as well as thermostabilized PPR vaccines and biosecurity protocols. 3. Overall outcomes include better systems for delivering animal health technologies, increased access to services for smallholders, and improved productivity and economic returns in value chains.

1. CRP 3.7
Update on animal health component 1.1
Phil Toye (ILRI)
Component 1.1: Animal Health
CGIAR Research Program on Livestock and Fish
Planning Meeting
ILRI Nairobi
27-29 September 2011

2. General Implementation Strategy
• Focus on vaccines, diagnostics and biosecurity
protocols for infectious diseases
• Two interdependent activities
1. VC assessment (Th. 2)
• infectious disease constraints
• policy & institutional constraints
2. Current projects (generic platforms)

3. Overall Outcomes
• Development of better systems to deliver existing
and forthcoming vaccines
• Development of better vaccines and diagnostics
targeted on priority diseases in selected value chains
• Development of appropriate biosecurity systems
• Development of delivery systems that increase
access to animal health services to women livestock
keepers, and poor smallholders

4. Overall Outcomes
• Improved systems and capacities for monitoring
evolution, introduction and spread of pathogens (CRP
4.3)

5. Existing Projects
• East Coast fever – vaccine
• support of current vaccine
• development of subunit vaccine
• generic platforms –
• antigen identification
• antigen delivery systems
• challenge trials
• vaccine delivery
Resources: Various - $ 1.37M

6. Existing Projects
• CBPP – vaccine & diagnostic
• development of subunit vaccine
• development of diagnostic assay
• generic platforms
• antigen i/d and delivery
• diagnostic assay platforms
• challenge trials
• vaccine / diagnostic delivery, modelling
Resources: Various - $ 1.76 M

7. Existing Projects
• African swine fever – biosecurity, diagnostics
• transmission dynamics
• social networks
• rapid diagnosis
• generic platforms -
• diagnostic assay platforms
• epidemiology for intervention
Resources: Various - $ 1.24 M

8. Existing Projects
• Peste des petits ruminants – vaccine
• thermostabilization
• vaccine delivery
• generic platforms
• thermostabilization
• epidemiology
• control programs
Resources: $ 1.76 M

9. Existing Projects
• Porcine cysticercosis / trypanosomiasis –
diagnostics (CRP4.3)
• pen-side assay
• generic platforms
• rapid diagnostic assay technology
• antigen identification
Resources: $ 125k

10. Existing Projects
• Field studies – VC assessment (CRP4.3)
• IDEAL, PAZ, AVID, ESEI
• generic platforms
• verification of PE, surveys
• samples
• biobanking
Resources: IFAD impending; 0.5M

11. Existing Projects
• ICARDA
• Dairy goat – Afghanistan (40% of
180k)
• CBBP sheep – Ethiopia (15% of 700k,
impending)
Resources: $ 177k

12. Existing Projects
• CIAT
• Martens – Colombia (15% of 81k)
• Martens – Pig in Colombia (75% of
82k, impending)
• Peters – Dairy in Col., Nic., (5% of
2580k impending)
• van der Hoek - USDA FFPr in Nic.,
(5% of 200k, impending)
Resources: $ 12 / 200 k

13. Outputs
East Coast fever – vaccine
2012
• Composition of ITM and comparison to field
strains
• Comparative genomics
2013
• CTL adjuvants
• CTL response (antigens, MHC)

14. Outputs
CBPP – diagnostics and vaccine
2012
• Candidate diagnostic antigens
• Validated challenge model
2013
• Validated diagnostic antigens
• Candidate vaccine antigens

15. Outputs
ASF – biosecurity, diagnostics
2013
• Improved understanding transmission
dynamics of ASF virus and social
networks of pig producers
2014
• Improved biosecurity protocols
• Improved assays for ASF diagnosis

16. Outputs
PPR – vaccine
2012
• Validated thermostabilization protocol
2013
Improved understanding of animal health
service delivery options, especially for
PPR

17. Outputs
World Fish
2012
• Policy advice on control of spread of
disease developed.

18. Outputs
CIAT
2012
• Establish comprehensive baseline information
on the impacts on production and economics of
pig diseases and potential disease measures
(including reports on A. pig production
activities and diseases for target areas; B. Cost
effective disease control including CSF
vaccination strategies implemented with
serological monitoring to assess degree of
protection and optimise vaccination

19. Outputs
Value chain analysis (Theme 2)
2012
• Initial rapid assessment of technology gaps,
epidemiological patterns, economic importance and
institutional limitations in mitigating animal disease
constraints in target value chains.
2013
• Identification of combinations of technology,
epidemiological knowledge and institutional change
to solve specific animal health problems

20. Outcomes
2012 / 2013
• Improved aquaculture biosafety and biosecurity
measures adopted and being used
• Prevention of alien pathogens by control of
introduction alien species for aquaculture
•Vaccine and diagnostic assay researchers and/or
manufacturers using data and antigens to design,
make or ascertain the prospects for new or
improved animal technologies of benefit in the
target value chains.

21. Outcomes
2012 / 2013 (cont.)
• International, regional and national authorities
and researchers using the data to develop and
disseminate improved biosecurity protocols.
• Productivity and economic returns of village
pig systems and reduce the risks to human health
along the market chain in SE Asia and Eastern
Africa are improved

22. Partners
• Academic
• Commercial
• Development
• International / regional

23. Priorities for Resource Mobilization
2012
Identify gaps in funding to achieve outputs and
target potential sources
Recruit FTE to undertake VCA (Th. 2)

24. Priorities for Organizational, Capacity
Development and Communication Activities
Ensure collaborative links with FAO, CIRAD and
others are functioning well
Restructure team to match needs identified in VC
assessment exercise
Develop effective, sustainable communication
strategies to link researchers with value chain
participants to identify needs

25. Priorities for Organizational, Capacity
Development and Communication Activities
Develop effective, sustainable communication
strategies to link researchers across value chains to
facilitate development of solutions and
dissemination of results
Seek further integration of ILRI led work in Uganda
and Viet Nam with CIAT led activities in SE Asia