Cot curve, melting temperature, unique and repetitive DNA
ILRI program outline: Animal and Human Health
1. ILRI program outline: Animal and
Human Health
Vish Nene and Delia Grace
ILRI Institute Planning Meeting
4-7 October 2016
2. Animal and human health – AHH – a DRAFT
Bring health-related activities under one program at ILRI
Promote a trans-disciplinary approach to health:
To increase the productivity of tropical livestock through better animal health
To reduce the negative impacts of agriculture on human health
(To improve animal, human and ecosystem health = one health)
Current thematic areas of research at ILRI
Vaccines & diagnostics
Herd health
Zoonoses & EID
Food safety
3. Animal and human health – AHH
CRP phase two mapping
Herd health
Vaccines
and
diagnostics
Zoonoses and
EID
Food Safety
A4NH Livestock
5. Animal and human health – AHH
cross ILRI program/CRP linkages
Overlaps with ILRI programs
Many!
Other CRP alignments
Agri food systems
CRP Livestock: Feed, Genes, LAFS, environment
CRP Fish
Global integrating programs
A4NH – Food systems for healthier diets
CCAFS – Climate smart technologies & practices
Big data
6. Nairobi
• David
• Ken
• Daisy
Vaccine Biosciences & Tick Unit: Who,
where, what?
African swine fever (ASF)
Malignant catarrhal fever (MCF)
Peste des petits ruminants (PPR)
Rift Valley Fever (RVF)
Contagious bovine pleuropneumonia (CBPP)
Contagious caprine pleuropneumonia (CCPP)
East Coast fever (ECF)
Ticks (and tick-borne pathogens)
Nairobi
• Vish
• Lucilla
• Nick
• Anna
• Sam
• Anne
• Elise
• Flavio
• Annie
Nairobi
• Elias
• Rosemary
• Stephen
• Benjamin
• John
• Liz
• Thomas
• Gecharicha
• Cecilia
• Jared
• Robert
• Stephen
• Naftaly
• Milton
• Mary
7. Herd health team: Who, where, what?
Aims to understand impact of infectious and non-infectious diseases
on livestock productivity in smallholder systems worldwide and to
develop interventions to address these constraints
Disease
constraints,
production risks
and resulting
burden
Interventions at herd
level: prevention,
food safety, welfare,
AM use, husbandry
Interventions at
national/regional
level: control
programs,
surveillance
Access to AH
services: gender
sensitive, novel
business models
ONEHEALTH
CAPACITY
Addis
• Barbara
• Biruk
• Hiwot
Kenya/Tz
• Henry
Uganda/Mali
• Michel
8. Food Safety Zoonoses: Who, where, what?
Food safety
Food borne disease in CRP L&F value chains
Aflatoxins in ASF, and as productivity constraint
Emerging infectious disease
Disease and land use change especially VBD & irrigation
Priority diseases: HPAI, Ebola
AMR pathogens and AM use in livestock
Neglected zoonoses
Lepto, strep suis, brucellosis, cysticercosis, Q fever
Trichinella, erysipelothrix
Animal health & Human Nutrition
Cost of disease, parasites, climate change
Nutrition and animal source foods
Nairobi
• Delia
• Bernard
• Johanna
• Silvia
• Paula
Vietnam
• Hung
• Fred
• Max
• Hu Suk
Uganda
• Kristina
Zambia
• Mwansa
• Theo
India
• Ram
Japan
• Kohei
• Tezira
• Emmanuel
• Nicholas
• Sarah
• Martin
• Thinh
• Wacera
• Ngubia
• Rose
• Caroline
• Mustafa
• Thanh
9. Zoonotic and Emerging Diseases: Who, where, what?
Team of ~20 in Nairobi
Pathogen biology and epidemiology
Antimicrobial resistance
Livestock-human interface
Wildlife interface
Environment and disease transmission
Urban Zoo
Studies from the
microsatellite to the
satellite in space
Nairobi
Busia
Liverpool
London
Edinburgh
Oxford
In 2017+:
A4NH CRP
target
countries
10. Scientists & science support
i
Uganda=2
Kenya =
18 Ethiopia = 3
(2)
India = (1)
Japan
=0.2
Vietnam = 3
Zambia=2
Scientists=31
Support
Communications
Technicians
Research assistants
Administration
Finance
Program management
Drivers
Office cleaning
14. Animal and Human Health
CoA
Priorities
CoA Health
Systems
CoA Vx
Diagnostics
CoA Herd
Health AMR SC Healthy
diets
Upstream
Areas of integration
Upstream
Delivery/impact
Foresight/evidence
3 groups
Delivery/impact
Option 3: Development, delivery/impact, evidence/foresight
Evidence/foresight
HH CoA
Disease in
landscapes
CoA
Zoonoses
CoA AMR
FS CoA
Evidence
FS CoA
Impact
SC Aflatoxins
15. Animal and Human Health
AH CoA Vx
Diagnostics
CoA
Priorities
CoA Health
Systems
CoA Herd
Health AMR
Upstream
Areas of integration
Upstream/ lab
Downstream/ epidemiology
2 groups
Downstream
Option 1: Upstream, downstream
FLAGSHIPS
AH= Animal Health
FS= Food Safety
HH = Improving Human Health
HH CoA
Disease in
landscapes
CoA
Zoonoses
CoA AMR
FS CoA
Evidence
CoA
Impact
SC Aflatoxins
CoA= cluster of
activities
SC= sub cluster of
activities
16. Animal and Human Health
SC Healthy
diets
CoA
Priorities
CoA Health
Systems
CoA Vx
Diagnostics
CoA Herd
Health AMR
CRP Livestock CRP A4NH
Areas of integration
FS Priorities/HH/Health Systems – 4 people
FS Vx Dx – 8 people
FS Human Health –5 people
FS Food Safety – 7/8 people
2, 3 or 4
groups
Option 2: CRP mapped
HH CoA
Disease in
landscapes
CoA
Zoonoses
CoA AMR
FS CoA
Evidence
CoA
Impact
SC Aflatoxins
17. Areas for integration
• What is One Health and what does it means for ILRI
• Hung/ Edward/Anne L/Silvia, Fred, Nicholas
• Making the most of ILRI labs
• Anne L, Nicholas, Johanna, Eric, Anna, Flavio, Michel
• Animal & human health in CRP Livestock value
chains
• Barbara, Kristina, Michel, Annie, Silvia, Paula, Fred
• Product lines from discovery to delivery
• Lucilla/Elisa/Annie/Henry/Ram
19. This presentation is licensed for use under the Creative Commons Attribution 4.0 International Licence.
better lives through livestock
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ILRI thanks all donors and organizations who globally supported its work through their contributions
to the CGIAR system
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Better livestock health linked with better breeds and feed
Institute for Infectious Animal Diseases, TAMU.
A one health lens
Institute for Infectious Animal Diseases, TAMU.
A one health lens
Livestock and A4NH CRPs.
Institute for Infectious Animal Diseases, TAMU.
A one health lens
Livestock and A4NH CRPs.
Function based: 3 groups
Lab (9); CRP value chains (8); global (7)
Advantage: allows one health and synergies, balanced group. Disadvantage: doesn’t follow CRP, some change in structure
Upstream: Vish, Lucilla, Nicholas, Anne, Anna, Elise, Samuel, Flavio, (Naftaly)
Delivery: Barbara, Michel, Henry, Edward, Silvia, Fred, Hung, (Ram, Kristina)
Foresight/global: Delia, Eric, Annie, Bernard, Johanna, Hung, Hu Suk, (Ulf, Tim, Kohei, Paula)
Function based: 3 groups
Lab (9); CRP value chains (8); global (7)
Advantage: allows one health and synergies, balanced group. Disadvantage: doesn’t follow CRP, some change in structure
Upstream: Vish, Lucilla, Nicholas, Anne, Anna, Elise, Samuel, Flavio, Edward (Naftaly)
Downstream: Delia, Barbara, Michel, Henry, Edward, Silvia, Fred, Hung,, Eric, Annie, Bernard, Johanna, Hung, Hu Suk (Ram, Kristina, Ulf, Tim, Kohei, Paula)
A simple way of organising is 4 sub-groups corresponding to CRP structures.
Advantage: maps onto existing CRP structure, balanced groups. Disadvantage: no synergies or OH, some change in group structure
AH group: Barbara, Michel, Henry, Edward, (Ulf)
VxDx group: Vish, Lucilla, Nicholas, Anne, Anna, Elise, Samuel, Flavio, (Naftaly)
FS group: Delia, Silvia, Johanna, Fred, Hung (Ram, Kohei, Kristina, Paula)
IHH group: Eric, Annie, Bernard, Hu Suk, (Tim)