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Unlocking livestock development potential through science, influence and capacity development
ILRI APM, Addis Ababa, 15-17 May 2013
Developing capacity Influencing decisions
Mapping	
  distribu.ons	
  of	
  .cks	
  and	
  .ck-­‐borne	
  diseases	
  in	
  Africa:	
  
effects	
  of	
  climate	
  change	
  and	
  the	
  implica.ons	
  for	
  human	
  and	
  
animal	
  health.	
  
	
  
	
  
This	
  document	
  is	
  licensed	
  for	
  use	
  under	
  a	
  Crea3ve	
  Commons	
  A6ribu3on-­‐Noncommercial-­‐Share	
  Alike	
  3.0	
  Unported	
  License	
  	
  	
  	
  	
  	
  	
  	
  May	
  2013	
  
	
  
3 strategic lessons on:	
  
!   Aiding	
  .ck	
  and	
  .ck-­‐borne	
  disease	
  
control	
  protocols	
  
	
  
Rothen,	
  J.,	
  Bishop,	
  R.,	
  Mwaura,	
  S,	
  Pflüger,	
  V.,	
  Daubenberger,	
  C.,	
  Olds,	
  C.	
  
Delivering science
THE	
  PROBLEM	
  
	
  
	
  
Tick	
  distribu.ons	
  are	
  determined	
  by	
  clima.c	
  factors	
  such	
  as	
  
temperature,	
  precipita.on	
  and	
  humidity.	
  
	
  
Tick	
   distribu.ons	
   are	
   shiKing	
   drama.cally	
   due	
   to	
   climate	
  
change.	
   	
   Consequently,	
   the	
   epidemiology	
   of	
   .ck-­‐borne	
  
diseasess	
   are	
   changing	
   with	
   far	
   reaching	
   implica.ons	
   for	
  
animal	
  and	
  human	
  health.	
  
	
  
Maps	
  ploMng	
  current	
  .ck	
  distribu.ons	
  in	
  Africa	
  are	
  needed	
  
to	
  understand	
  and	
  predict	
  .ck-­‐borne	
  diseases.	
  	
  
	
  
Matrix-­‐assisted	
   laser	
   desorp.on/ioniza.on-­‐Time	
   of	
   flight	
  
(MALDI-­‐TOF)	
   mass	
   spectroscopy	
   is	
   able	
   to	
   iden.fy	
   .ck	
  
species	
   cheaper	
   and	
   faster	
   than	
   other	
   molecular	
  
techniques.	
  
	
  
	
  
	
  
	
  
!   Mapping	
  .cks	
  for	
  human	
  and	
  livestock	
  
health	
  
!   Developing	
  databases	
  for	
  .ck	
  
iden.fica.on	
  
!   Developing	
  predic.on	
  models	
  for	
  .ck	
  
and	
  .ck-­‐borne	
  disease	
  distribu.on	
  
	
  
!   Training	
  human	
  and	
  veterinary	
  health	
  
professionals	
  in	
  .ck	
  iden.fica.on	
  
!   Mentoring	
  students	
  
	
  
THE	
  SOLUTION	
  
	
  
	
  
Collect	
  .cks	
  from	
  livestock,	
  humans	
  and	
  companion	
  
animals	
  as	
  well	
  as	
  field	
  traps.	
  
	
  
	
  
Iden.fy	
  .cks	
  using	
  MALDI-­‐TOF.	
  
	
  
	
  
	
  
Iden.fy	
  any	
  .ck-­‐borne	
  diseases	
  present	
  in	
  collected	
  .cks.	
  
	
  
	
  
	
  
Create	
  new	
  distribu.on	
  maps	
  for	
  .ck	
  species	
  within	
  
Africa.	
  
	
  
	
  
	
  
Create	
  models	
  for	
  further	
  .ck	
  and	
  .ck-­‐borne	
  disease	
  
distribu.ons.	
  	
  
	
  
	
  
THE	
  PROGRESS	
  
	
  
	
  
Reference	
   MALDI-­‐TOF	
   profies	
   have	
   been	
   created	
   for	
  
economically	
  important	
  .cks	
  of	
  livestock	
  in	
  Africa.	
  
	
  
Field	
   .ck	
   species	
   correctly	
   iden.fied	
   in	
   a	
   ‘proof	
   of	
  
concept’	
  experiment.	
  
	
  
Large	
  scale	
  .ck	
  collec.ons	
  should	
  be	
  carried	
  out	
  covering	
  
various	
  geographic	
  areas	
  within	
  Africa	
  and	
  the	
  data	
  used	
  
to	
  update	
  .ck	
  distribu.on	
  maps.	
  
	
  
	
  
	
  
COLLABORATORS	
  
	
  
Claudia	
  Daubenberger,	
  Swiss	
  Tropical	
  and	
  Public	
  Health	
  
Ins.tute,	
  Switzerland.	
  
	
  
Valen.n	
  Pflüger	
  and	
  Julian	
  Rothen,	
  Mabritec,	
  Switzerland.	
  
	
  
	
  

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Mapping distributions of ticks and tick-borne diseases in Africa: Effects of climate change and the implications for human and animal health

  • 1. Unlocking livestock development potential through science, influence and capacity development ILRI APM, Addis Ababa, 15-17 May 2013 Developing capacity Influencing decisions Mapping  distribu.ons  of  .cks  and  .ck-­‐borne  diseases  in  Africa:   effects  of  climate  change  and  the  implica.ons  for  human  and   animal  health.       This  document  is  licensed  for  use  under  a  Crea3ve  Commons  A6ribu3on-­‐Noncommercial-­‐Share  Alike  3.0  Unported  License                May  2013     3 strategic lessons on:   !   Aiding  .ck  and  .ck-­‐borne  disease   control  protocols     Rothen,  J.,  Bishop,  R.,  Mwaura,  S,  Pflüger,  V.,  Daubenberger,  C.,  Olds,  C.   Delivering science THE  PROBLEM       Tick  distribu.ons  are  determined  by  clima.c  factors  such  as   temperature,  precipita.on  and  humidity.     Tick   distribu.ons   are   shiKing   drama.cally   due   to   climate   change.     Consequently,   the   epidemiology   of   .ck-­‐borne   diseasess   are   changing   with   far   reaching   implica.ons   for   animal  and  human  health.     Maps  ploMng  current  .ck  distribu.ons  in  Africa  are  needed   to  understand  and  predict  .ck-­‐borne  diseases.       Matrix-­‐assisted   laser   desorp.on/ioniza.on-­‐Time   of   flight   (MALDI-­‐TOF)   mass   spectroscopy   is   able   to   iden.fy   .ck   species   cheaper   and   faster   than   other   molecular   techniques.           !   Mapping  .cks  for  human  and  livestock   health   !   Developing  databases  for  .ck   iden.fica.on   !   Developing  predic.on  models  for  .ck   and  .ck-­‐borne  disease  distribu.on     !   Training  human  and  veterinary  health   professionals  in  .ck  iden.fica.on   !   Mentoring  students     THE  SOLUTION       Collect  .cks  from  livestock,  humans  and  companion   animals  as  well  as  field  traps.       Iden.fy  .cks  using  MALDI-­‐TOF.         Iden.fy  any  .ck-­‐borne  diseases  present  in  collected  .cks.         Create  new  distribu.on  maps  for  .ck  species  within   Africa.         Create  models  for  further  .ck  and  .ck-­‐borne  disease   distribu.ons.         THE  PROGRESS       Reference   MALDI-­‐TOF   profies   have   been   created   for   economically  important  .cks  of  livestock  in  Africa.     Field   .ck   species   correctly   iden.fied   in   a   ‘proof   of   concept’  experiment.     Large  scale  .ck  collec.ons  should  be  carried  out  covering   various  geographic  areas  within  Africa  and  the  data  used   to  update  .ck  distribu.on  maps.         COLLABORATORS     Claudia  Daubenberger,  Swiss  Tropical  and  Public  Health   Ins.tute,  Switzerland.     Valen.n  Pflüger  and  Julian  Rothen,  Mabritec,  Switzerland.