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Abril 2011




Boletín
Nanomedicina


               generado por VIGIALE, IALE Tecnología.
HIDDEN TEXT TO MARK THE BEGINNING OF THE TABLE OF CONTENTS




                                                             INDICE
NOTICIAS
 1. NANO-systems to accelerate recovery after surgery without side effects                      2
 2. Nanotechnology for the treatment of coronary in stent restenosis: A clinical perspective    2
 3. Sandia and UNM lead effort to destroy cancers                                               2
 4. Nanoscience may hold key to surgical recovery                                               2
 5. Scientists engineer nanoscale vaults to encapsulate 'nanodisks' for drug delivery           3
 6. Promising data demonstrating the anti-tumor activity of a novel cancer target               3
 7. Stanford research moves nanomedicine one step closer to reality                             3
 8. Pediatric Center Focuses on Nano-Medicine for Pediatric Care                                3
 9. IBM nanomedicine breakthrough to aid antibiotics                                            4
 10. Nanofiber spheres show promise for knee cartilage repair                                   4
 11. Nanotech device identifies cancer and HIV                                                  4
 12. Nanotechnology vehicle speeds numbing of topical lidocaine                                 4
 13. Injectable gel could spell relief for arthritis sufferers                                  4
 14. DNA stretching: new technique to detect illnesses                                          5
 15. Pre-clinical results for oral delivery of the anti-cancer drug                             5
 16. New DNA nanoforms take shape                                                               5
 17. NCKU and NRC made innovative cancer diagnostic and treatment discoveries                   5
 18. Nanofiber spheres carrying cells injected into wounds to grow tissue                       6
 19. First look at the mechanics of membrane proteins                                           6
 20. Nanoscience used to identify cancer drug effectiveness                                     6
 21. The world's smallest wedding rings                                                         6
 22. Hand-held NMR instrument yields rapid analysis of human tumors                             7
 23. Nanoparticles enhance detection of circulating tumor cells                                 7
 24. 'Good cholesterol' nanoparticles seek and destroy cancer cells                             7
 25. Study develops new approaches for sorting out complexities of cancer cells                 7
 26. Chemical engineers at UCSB design molecular probe to study disease                         8
 27. Personalized therapies for inflammation                                                    8
 28. Study ways to improve treatment of inflammatory bowel disease                              8
 29. La batalla entre microRNAs y oncogenes                                                     8


PATENTES
 30. Patentes publicadas este mes                                                               9
 31. Origen de los principales actores del mes                                                  9
 32. Principales temas tratados en las patentes del mes                                        10
 33. Principales titulares de las patentes del mes                                             10
 34. Principales inventores que patentaron este mes                                            11
INDICE
35. US20110097401A1: Methods for treating gastrointestinal disorders                            11
36. US20110091560A1: Compositions of nanoparticles and methods of making the same               11
37. US20110091373A1: PAA nanoparticles for enhancement of tumor imaging                         12
38. US20110097277A1: Particles coated with zwitterionic polymers                                12
39. US20110093020A1: Poly-porous hollow screw for target delivery of growth factors...          12
40. WO2011050357A2: Protein arginine deiminase inhibitors for rheumatoid arthritis and cancer   12
41. US20110097377A1: Methods and devices for correcting spinal deformity...                     13
42. US20110093089A1: Electronically controlled prosthetic system                                13
43. US20110097420A1: Cement products and methods of making and using the same                   13
44. US20110091353A1: Methods for sterilizing tissue                                             13
45. US20110098558A1: System and method for use of nanoparticles imaging and diagnosis           14
46. WO2011048493A1: Coated capsules and tablets of fatty acid oil mixture                       14


EVENTOS, CURSOS Y
SEMINARIOS
47. Smart Polymer Systems 2011                                                                  14
48. EuroNanoForum 2011                                                                          14
49. European Perspectives in Personalised Medicine                                              15
50. 6th Intl Congress of Nano Bio Clean Tech                                                    15
51. 4th European-Conference for Clinical Nanomedicine                                           15
52. Nanotech Conference and Expo 2011                                                           15
53. Nanomedicine 2011 - 3rd ESF Summer School                                                   16
54. Greener Nano 2011                                                                           16
55. EuroNanoForum 2011                                                                          16
56. European Perspectives in Personalised Medicine                                              16
57. Safety issues of Nanomaterials along their life cycle Symposium                             16
58. 7th International Dendrimer Symposium                                                       17
59. Biomedical Nanotechnology                                                                   17
60. Nanomaterials 2011                                                                          17
61. EUPOC 2011, Biobased Polymers and Related Biomaterials                                      17
62. Biomedical Applications in Nanotechnology                                                   18
63. NanoBio-Europe 2011                                                                         18
64. III Simposio sobre Nanotecnologías CINVESTAV/Sigma Aldrich                                  18
65. Conferencia Internacional IMMUNONET: Las Nuevas Tendencias en Inmunoterapia                 18
66. Nanotech China                                                                              19


ARTÍCULOS-
CIENTÍFICOS
INDICE
67. Artículos científicos publicados este mes                                                            19
68. Principales temas tratados en los artículos científicos del mes                                      20
69. Principales entidades con publicaciones este mes                                                     20
70. Principales investigadores que publicaron este mes                                                   21
71. Balancing forces: architectural control of mechanotransduction                                       21
72. Supramolecular self-assembly of biopolymers with carbon nanotubes for biomimetic...                  21
73. Dual temperature/pH-sensitive drug delivery of poly... nanogels                                      22
74. Positive potential operation of a cathodic... immunosensor for cancer biomarker detection            22
75. Intracellular pH sensing using p-aminothiophenol functionalized gold nanorods...                     22
76. Quantum dot-aptamer nanoprobes for recognizing and labeling influenza A virus particles              22
77. Lithography-based nanoelectrochemistry                                                               23
78. Transport of single cells using an actin bundlemyosin bionanomotor transport system                  23
79. DNA origami with complex curvatures in three-dimensional space                                       23
80. Biostability of y-Fe2O3 nano particles ..cytotoxicity assays on various tumor cell lines             23
81. Activation of neural and pluripotent stem cell signatures...                                         24
82. Controlled growth and differentiation of MSCs on grooved films assembled ...                         24
83. Validation of the calibrated thrombin generation test (cTGT)...                                      24
84. Drug delivery: One nanoparticle, one kill                                                            24
85. Specific penetration and accumulation of a homing peptide within atherosclerotic plaques             24
86. Application of fiber optic ATR-FTIR methods.. for therapeutic delivery systems                       25
87. Preclinical screening of anti-HER2 nanobodies for molecular imaging of breast cancer                 25
88. SiRNA delivery with exosome nanoparticles                                                            25
89. Reactions inside nanoscale protein cages                                                             25


NORMATIVAS
90. CEN ISO/TS 13830:2011                                                                                26
91. Nanoscale carbon toxicity testing proposal submitted to EPA                                          26
92. ASTM WK32796 - New Test Method                                                                       26


INFORMES Y OTRAS
PUBLICACIONES
93. Molecular Diagnostics in Cancer Testing                                                              27
94. Market Analyst Dissects Global Nano-medicine Market                                                  27
95. Ethical and Societal Aspects of Nanotechnology Enabled ICT and Security Technologies                 27
96. Nanotechnology Research Directions for Societal Needs in 2020 Retrospective and Outlook              27
97. Double-walled carbon nanotubes for medical imaging by MRI and other biomedical applications          28

98. Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future ...   28
Nanomedicina
             NOTICIAS
             NANO-systems to accelerate recovery after surgery without side
             effects
             Publicada en Azonano - Noticias sobre Nanomedicina, 04/29/2011.

             By Cameron ChaiThe University of York research team at the Department of Chemistry has created artificial
             molecules that can attach the chemical drug heparin that could replace protamine.

                  ver más...



             Nanotechnology for the treatment of coronary in stent restenosis: A
             clinical perspective
             Publicada en Nanotechnology Now, 04/28/2011.

             Coronary in stent restenosis remains a significant limitation to the long term efficacy of coronary artery stent
             placement. In this review the authors review the pathophysiology of coronary instent restenosis, together with an
             overview of the current treatment modalities.


                  ver más...



             Sandia and UNM lead effort to destroy cancers
             Publicada en Nanotechwire.com - Bio/Medicine, 04/28/2011.

             Melding nanotechnology and medical research, Sandia National Laboratories, the University of New Mexico, and the
             UNM Cancer Research and Treatment Center have produced an effective strategy that uses nanoparticles to blast
             cancerous cells with a mélange of killer drugs.

                  ver más...



             Nanoscience may hold key to surgical recovery
             Publicada en Science Daily - Nanomedicina, 04/28/2011.

             Researchers from the University of York's Department of Chemistry have developed synthetic molecules capable of
             binding the chemical drug heparin, which they believe may provide an alternative to protamine.

                  ver más...




Abril 2011                                                                                                            Página 2
Nanomedicina
             Scientists engineer nanoscale vaults to encapsulate 'nanodisks' for
             drug delivery
             Publicada en Nanotechwire.com - Drug Delivery, 04/28/2011.

             In recent years, researchers have grappled with the challenge of administering therapeutics in a way that boosts their
             effectiveness by targeting specific cells in the body while minimizing their potential damage to healthy tissue.


                  ver más...



             Promising data demonstrating the anti-tumor activity of a novel
             cancer target
             Publicada el 04/22/2011.

             Tekmira Pharmaceuticals Corporation, a leading developer of RNA interference (RNAi) therapeutics, announced
             today that promising preclinical data from its collaboration with the National Cancer Institute (NCI) has been
             published in Oncogene, one of the world's leading cancer journals.

                  ver más...



             Stanford research moves nanomedicine one step closer to reality
             Publicada el 04/20/2011.

             A class of engineered nanoparticles gold-centered spheres smaller than viruses has been shown safe when
             administered by two alternative routes in a mouse study led by investigators at the Stanford University School of
             Medicine. This marks the first step up the ladder of toxicology studies that, within a year and a half, could yield to
             human trials of the tiny agents for detection of colorectal and possibly other cancers.


                  ver más...



             Pediatric Center Focuses on Nano-Medicine for Pediatric Care
             Publicada el 04/18/2011.

             Researchers at the Center for Pediatric Nanomedicine (CPN) will design specific, nanoparticles in an endeavor to
             treat pediatric illnesses. Focus will be on pediatric heart disease and thrombosis, infectious diseases, cancer, sickle
             cell disease and cystic fibrosis.

                  ver más...




Abril 2011                                                                                                                  Página 3
Nanomedicina
             IBM nanomedicine breakthrough to aid antibiotics
             Publicada el 04/18/2011.

             IBM researchers and scientists from the Institute of Bioengineering and Nanotechnology on Sunday unveiled a
             nanomedicine breakthrough biodegradable nanoparticles that make antibiotics physically attracted to infected cells.


                  ver más...



             Nanofiber spheres show promise for knee cartilage repair
             Publicada en Nanomedicine Research - News, 04/18/2011.

             Using injectable hollow, biodegradable nanofiber spheres as cell carriers is likely to repair knee cartilage more
             effectively than current methods, said US researchers in a paper published online in Nature Materials this week.


                  ver más...



             Nanotech device identifies cancer and HIV
             Publicada en BSI -Nanotechnology news, 04/18/2011.

             A new device has been created by scientists from Harvard University and the Massachusetts Institute of Technology
             (MIT) that is capable of detecting cancer cells and indicators of HIV in blood. Using carbon nanotubes to create posts
             measuring 30 microns in diameter, the team has developed technology that is capable of catching tiny objects flowing
             through a microfluidic system.

                  ver más...



             Nanotechnology vehicle speeds numbing of topical lidocaine
             Publicada en Nanotechnology Now, 04/18/2011.

             A 4% topical lidocaine cream with a nanotechnology-based vehicle in development provided superior pain relief
             before facial filler injections, compared with the most commonly-used topical anesthetic cream, according to patient
             and physician ratings in two split-face studies.

                  ver más...



             Injectable gel could spell relief for arthritis sufferers




Abril 2011                                                                                                                 Página 4
Nanomedicina
             Publicada en Nanotechwire.com - Bio/Medicine, 04/18/2011.

             Researchers from Brigham and Womens Hospital have developed a potentially new way to treat arthritis. Here their
             new gel (red, with yellow rectangles representing encapsulated medicine) is injected into an arthritic joint. There
             enzymes (black image) associated with arthritis break down the biodegradable gel, releasing the medicine.


                  ver más...



             DNA stretching: new technique to detect illnesses
             Publicada en Science Daily - Nanomedicina, 04/18/2011.

             Scientists are making DNA sequences being passed through nanochannels a thousand times thinner than a human
             hair to the point that they take on the form of diminutive spaghetti. This is an innovative technique, known as DNA
             stretching, and is one of the lines of research in which CIC microGUNE is working, and about which they have
             already published two scientific articles and are shortly to apply for a patent.


                  ver más...



             Pre-clinical results for oral delivery of the anti-cancer drug
             Publicada en Nanotechwire.com - Drug Delivery, 04/18/2011.

             Yissum Research Development Company Ltd., the technology transfer company of the Hebrew University of
             Jerusalem, announced today successful pre-clinical data of oral delivery of Docetaxel, an anti-cancer drug, utilizing a
             novel nanotechnology platform.

                  ver más...



             New DNA nanoforms take shape
             Publicada el 04/18/2011.

             Miniature architectural forms have been constructed through a revolutionary technique known as DNA origami. Now,
             Hao Yan, Yan Liu and their colleagues at Arizona State University's Biodesign Institute have expanded the capability
             of this method to construct arbitrary, two and three-dimensional shapes, mimicking those commonly found in nature.


                  ver más...



             NCKU and NRC made innovative cancer diagnostic and treatment
             discoveries




Abril 2011                                                                                                                  Página 5
Nanomedicina
             Publicada el 04/18/2011.

             A Taiwanese research team led by Prof. Dar-Bin Shieh of Institute of Oral Medicine in Medical College at National
             Cheng Kung University (NCKU) has partnered with a research group led by Dr. Dennis Whitefield from National
             Research Council (NRC) of Canada to develop innovative cancer diagnostic and treatment technologies.


                  ver más...



             Nanofiber spheres carrying cells injected into wounds to grow
             tissue
             Publicada el 04/18/2011.

             For the first time, scientists have made star-shaped, biodegradable polymers that can self-assemble into hollow,
             nanofiber spheres, and when the spheres are injected with cells into wounds, these spheres biodegrade, but the cells
             live on to form new tissue.

                  ver más...



             First look at the mechanics of membrane proteins
             Publicada el 04/18/2011.

             In two new studies, researchers provide the first detailed view of the elaborate chemical and mechanical interactions
             that allow the ribosome - the cell's protein-building machinery - to insert a growing protein into the cellular membrane.


                  ver más...



             Nanoscience used to identify cancer drug effectiveness
             Publicada el 04/18/2011.

             The effectiveness of treatments for cancer could be better assessed using nanotechnology, it has been claimed. A
             scientist in Indiana in the US has been experimenting with nanopolymers and has discovered they could help to
             determine whether or not drugs are reaching the intended site.

                  ver más...



             The world's smallest wedding rings
             Publicada el 04/18/2011.

             Prof Alexander Heckel and his doctoral student Thorsten Schmidt from the "Cluster of Excellence for Macromolecular
             Complexes" at Goethe University were able to create two rings of DNA only 18 nanometers in size, and to interlock
             them like two links in a chain. Such a structure is called catenan, a term derived from the Latin word catena (chain).




Abril 2011                                                                                                                    Página 6
Nanomedicina
                  ver más...




             Hand-held NMR instrument yields rapid analysis of human tumors
             Publicada el 04/18/2011.

             Using a handheld molecular imaging device in combination with magnetic nanoparticles and a smartphone, a team of
             investigators from the Massachusetts General Hospital and Harvard Medical School has developed a fast, portable
             and potentially inexpensive method of detecting cancer from human biopsy samples.


                  ver más...



             Nanoparticles enhance detection of circulating tumor cells
             Publicada el 04/18/2011.

             Circulating tumor cells (CTCs), shed into the blood stream by tumors, are thought to provide a means of detecting
             cancer early, conducting a preliminary assessment of which anticancer agents might prove most effective at treating
             a given patient, and assessing whether a chosen therapy is working.

                  ver más...



             'Good cholesterol' nanoparticles seek and destroy cancer cells
             Publicada el 04/18/2011.

             High-density lipoprotein's hauls excess cholesterol to the liver for disposal, but new research suggests "good
             cholesterol" can also act as a special delivery vehicle of destruction for cancer.

                  ver más...



             Study develops new approaches for sorting out complexities of
             cancer cells
             Publicada el 04/18/2011.

             New drugs that specifically target the mutated genes responsible for cancer growth have shown great success in
             extending the lives of patients, with far fewer side effects than conventional anti-cancer therapies. Unfortunately,
             many patients become resistant to these drugs due to secondary mutations.

                  ver más...




Abril 2011                                                                                                               Página 7
Nanomedicina
             Chemical engineers at UCSB design molecular probe to study
             disease
             Publicada el 04/18/2011.

             Chemical engineers at UC Santa Barbara expect that their new process to create molecular probes may eventually
             result in the development of new drugs to treat cancer and other illnesses.

                  ver más...



             Personalized therapies for inflammation
             Publicada el 04/18/2011.

             Scientists at Barts and The London School of Medicine and Dentistry and Harvard Medical School, Boston have
             found a way of mimicking the body's natural mechanism of fighting inflammation. During inflammation cells release
             very small particles termed 'microparticles' that retain features of their parent cell.


                  ver más...



             Study ways to improve treatment of inflammatory bowel disease
             Publicada el 04/18/2011.

             CEA-Leti today announced a new project designed to develop a novel nanocarrier-based approach to improve the
             treatment of inflammatory bowel disease, and increasingly common condition in Europe.

                  ver más...



             La batalla entre microRNAs y oncogenes
             Publicada el 04/18/2011.

             La prestigiosa revista Blood publica en su último numero un artículo del Grupo de División Celular y Cáncer del
             CNIO, que dirige Marcos Malumbres, en el que se da cuenta de la batalla que libran los microRNAs -pequeños
             fragmentos de RNA- por modular y controlar la actividad de determinados oncogenes y evitar así que las células se
             conviertan en cancerosas.

                  ver más...




Abril 2011                                                                                                            Página 8
Nanomedicina
             PATENTES
             Patentes publicadas este mes
             Publicada el 04/30/2011.

             Fuente: Espacenet, USPTO




             Origen de los principales actores del mes
             Publicada el 04/30/2011.

             Fuente: Espacenet, USPTO




Abril 2011                                               Página 9
Nanomedicina
             Principales temas tratados en las patentes del mes
             Publicada el 04/30/2011.

             Fuente: Espacenet, UPSTO




             Principales titulares de las patentes del mes
             Publicada el 04/30/2011.

             Fuente: Espacenet, UPSTO




Abril 2011                                                        Página 10
Nanomedicina
             Principales inventores que patentaron este mes
             Publicada el 04/30/2011.

             Fuente: Especenet, USPTO




             US20110097401A1: Methods for treating gastrointestinal disorders

             Publicada el 04/29/2011.

             Inventor: Phillips Elaine. Titular: Meritage Pharma Inc (US). Resumen: Provided herein are compositions and
             formulations suitable for the treatment of gastrointestinal disorders. Also provided are methods for treating,
             preventing, or alleviating disorders of the gastrointestinal tract, for example, those involving the esophagus.


                  ver más...



             US20110091560A1: Compositions of nanoparticles and methods of
             making the same
             Publicada el 04/29/2011.

             Inventor: Smith Jeff (US). Titular: Burhnam Inst Medical Research (US). Resumen: Disclosed herein are
             compositions of nanoparticles. In some embodiments, the nanoparticles are Janus particles, where each particle
             includes a first component and second component that are exposed to the surface of the particle.

                  ver más...




Abril 2011                                                                                                         Página 11
Nanomedicina
             US20110091373A1: PAA nanoparticles for enhancement of tumor
             imaging
             Publicada el 04/29/2011.

             Inventor: Pandey Ravindra K. Titulares: Health Research Inc (US), Unic New York State Res Found (US); Univ
             Michigan (US). Resumen: A composition comprising PAA nanoparticles containing a post loaded tetrapyrollic
             photosensitizer and an imaging agent and methods for making and using same.

                  ver más...



             US20110097277A1: Particles coated with zwitterionic polymers
             Publicada el 04/29/2011.

             Inventor: Jiang Shaoyi. Titular: Univ Washington (US). Resumen: Nanoparticles zwitterionic polymers grafted thereto
             or grafted therefrom, and methods for making and using the nanoparticles. Zwitterionic nanogels, and methods for
             making and using the nanogels.

                  ver más...



             US20110093020A1: Poly-porous hollow screw for target delivery of
             growth factors...
             Publicada el 04/29/2011.

             Inventor y Titular: Wu Yangguan (US). Resumen: Present invention depicts a poly-porous (micropore) hollow screws
             as diffusion chamber filled with core matrix for targeted delivery of growth factors and bone marrow stem cells. The
             screws comprise at least two parts: the distal part of the screw consists of the tip of the screw made of poly porous
             material and hollow inside proximally.

                  ver más...



             WO2011050357A2: Protein arginine deiminase inhibitors for
             rheumatoid arthritis and cancer
             Publicada el 04/29/2011.

             Inventor: Thompson Paul R. Titular: Univ South Carolina (US). Resumen: In accordance with certain embodiments of
             the present disclosure, a self-assembling biodegradable nanoparticle is provided. The nanoparticle includes Cys-Val-
             Val-Val-Val-Val-Val-Lys-Lys conjugated with a synthetic polymer and has a diameter of from about 50 nm to about
             150 nm.

                  ver más...




Abril 2011                                                                                                               Página 12
Nanomedicina
             US20110097377A1: Methods and devices for correcting spinal
             deformity...
             Publicada el 04/29/2011.

             Inventor y Titular: Serhan Hassan (US). Resumen: A method of correcting spinal deformity, which includes locating
             pharmaceutical-loaded implants adjacent to targeted spinal growth plates, and then eluting the pharmaceutical onto
             the growth plates. Preferably, the method involves correcting spinal deformity by simply inserting a pharmaceutical-
             eluting pedicle screw onto the concave side of a scoliotic curve.

                  ver más...



             US20110093089A1: Electronically controlled prosthetic system
             Publicada el 04/29/2011.

             Inventor y Titular: Martin James J (US). Resumen: A prosthetic joint system for users comprising a housing having an
             interior cavity, a center axis in said interior cavity, and an attachment means for fixedly connecting said housing to
             said user...

                  ver más...



             US20110097420A1: Cement products and methods of making and
             using the same
             Publicada el 04/29/2011.

             Inventor: Lin Juchui Ray. Titular: Angstrom Medica (US). Resumen: Disclosed are cement products, methods of
             forming cement using the cement product, and methods of using the cement product in orthopedic and dental
             applications.... cement product includes a first component comprising a polymerizable resin .....optionally, the cement
             product includes a bioactive component to promote bone formation.


                  ver más...



             US20110091353A1: Methods for sterilizing tissue
             Publicada el 04/29/2011.

             Inventor y Titular: Burgess Wilson (US). Resumen: Methods are disclosed for sterilizing tissue to reduce the level of
             one or more active biological contaminants or pathogens therein, such as viruses, bacteria, yeasts, molds, fungi,
             prions or similar agents responsible, alone or in combination, for TSEs and/or single or multicellular parasites. The
             methods involve sterilizing one or more tissues with irradiation.

                  ver más...




Abril 2011                                                                                                                 Página 13
Nanomedicina
             US20110098558A1: System and method for use of nanoparticles
             imaging and diagnosis
             Publicada el 04/29/2011.

             Inventor: Weaver John B. Titular: Dartmouth College The Trustees (US). Resumen: A method for diagnosing certain
             types of cancers provides a nanoparticle agent to be uptaken by cancer cells for diagnosis and treatment of certain
             cancers. A compound containing nanoparticles is directed toward a tumor site, and then a predetermined time period
             passes to allow the nanoparticles to be uptaken by the cancer cells.

                  ver más...



             WO2011048493A1: Coated capsules and tablets of fatty acid oil
             mixture
             Publicada el 04/29/2011.

             Inventor: Klaveness JO Erik Johnsrud (NO). Titular: Pronova Biopharma Norge AS (NO). Resumen: Compositions
             comprising a fatty acid oil mixture and at least one free fatty acid in a coated capsule or a coated tablet form suitable
             for oral administration, and methods of use thereof, are disclosed.

                  ver más...



             EVENTOS, CURSOS Y SEMINARIOS
             Smart Polymer Systems 2011
             Publicada en AzoNanotechnology-Eventos, 04/28/2011.

             The conference aims to provide a comprehensive overview of the current state-of-the-art in the field and
             demonstrate, via a range of case studies and contributions from leading researchers, how companies might capitalise
             on this emerging technology.
             Fecha: May 25 - 26, 2011. Lugar: Mainz, Germany.

                  ver más...



             EuroNanoForum 2011
             Publicada el 04/18/2011.

             EuroNanoForum is a biannual event supported by the European Commission and organised within the framework of
             the Presidency of the European Union.
             Fecha: 30 May -1 June 2011. Lugar: Budapest, Hungary.

                  ver más...




Abril 2011                                                                                                                   Página 14
Nanomedicina
             European Perspectives in Personalised Medicine
             Publicada el 04/18/2011.

             This conference will bring together key stakeholders of the research community and the healthcare sector to identify
             the developments needed in order to contribute to the research for Personalised Medicine at European and national
             level, in the frame of the Innovation Union and beyond.
             Fecha: 12 - 13 May 2011. Lugar: Brussels, Belgium.

                  ver más...



             6th Intl Congress of Nano Bio Clean Tech
             Publicada el 04/18/2011.

             The conference will gather world class researchers, business executives and engineers from over 30 countries and
             cover the following topics: Nanomaterials, Nanobiotechnology, Molecular Engineering, Heath Safety Implications,
             Intellectual Property, Commercialization, Venture capital investment and other related topics.
             Fecha: June 20, 2011. Lugar: San Francisco, CA, USA.


                  ver más...



             4th European-Conference for Clinical Nanomedicine
             Publicada el 04/18/2011.

             The conference focuses on clinical application of novel developments innanoscience but also includes industrial
             topics, the expertise formregulatory authorities and discussion on ethical questions and widerimplications.
             Fecha: 23 May, 2011. Lugar: Basel, Switzerland.


                  ver más...



             Nanotech Conference and Expo 2011
             Publicada el 04/18/2011.

             Uniting innovators to bring nanotechnology from laboratory to marketplace. Nanotech 2011 brings together over
             5,000 technology and business leaders and experts from academia, government, startups and Fortune 1,000
             companies.
             Fecha: June 13, 2011. Lugar: Boston, MA, USA.

                  ver más...




Abril 2011                                                                                                              Página 15
Nanomedicina
             Nanomedicine 2011 - 3rd ESF Summer School
             Publicada el 04/18/2011.

             The ESF Summer School Nanomedicine 2011, has been designed to provide an intensive state-of the- art training
             across all of the sub-disciplines of Nanomedicine, and to foster discussion and exchange of ideas in a relaxed
             atmosphere.
             Fecha: June 19-24, 2011. Lugar: Wittenberg, Germany.

                  ver más...



             Greener Nano 2011
             Publicada el 04/18/2011.

             We will focus on two key research areas: highlight state-of-the-art in materials synthesis and characterization
             challenges, and discuss biological impacts of nanotechnology.
             Fecha: May 01 - 03, 2011. Lugar: Cupertino California, USA

                  ver más...



             EuroNanoForum 2011
             Publicada el 04/18/2011.

             EuroNanoForum is a biannual event supported by the European Commission and organised within the framework of
             the Presidency of the European Union.
             Fecha: May 30 - June 01, 2011. Lugar: Budapest, Hungary.

                  ver más...



             European Perspectives in Personalised Medicine
             Publicada el 04/18/2011.

             This conference will bring together key stakeholders of the research community and the healthcare sector to identify
             the developments needed in order to contribute to the research for Personalised Medicine.
             Fecha: 12-13 May 2011. Lugar: Square-Brussels Meeting Centre, Brussels

                  ver más...



             Safety issues of Nanomaterials along their life cycle Symposium




Abril 2011                                                                                                              Página 16
Nanomedicina
             Publicada el 04/18/2011.

             The aim of the Symposium is to discuss about the human and environmental impacts of nanomaterials along their life
             cycle from their production through their processing, use, and end of life (recycling and/or disposal). Fecha: 4-5 May,
             2011. Lugar: Terrassa, Barcelona, Spain.

                  ver más...



             7th International Dendrimer Symposium
             Publicada el 04/18/2011.

             An average of 300-400 participants attended these symposium from over 30 countries every two years.The
             symposium focuses on the scientific research, latest developments in technology, synthesis, characterizationand
             applications.
             Fecha: June 26 - July 1, 2011. Lugar: Gaithersburg, Maryland, USA.

                  ver más...



             Biomedical Nanotechnology
             Publicada en AzoNano-Nanomaterial Courses, 04/18/2011.

             Biomedical Nanotechnology is a course that investigates key areas in which nanotechnology can benefit biomedical
             applications, understanding of nanomaterials for various biomedical applications, wet and dry nanotechnology, and
             basics of nanofabrication. This course also introduces applications such as drug delivery, imaging and diagnostics,
             and tissue regeneration and engineering.
             Fecha: Continual. Lugar: online.

                  ver más...



             Nanomaterials 2011
             Publicada en NanoConferences.com, 04/18/2011.

             NanoMaterials 2011 will feature 2 plenary sessions and 3 parallel sessions with a change in focus from the previous
             editions. These 3 programme tracks will focus on: Policy, Business & Finance; and Synthesis and production...
             Fecha: June 07 - 09, 2011. Lugar: London, UK.


                  ver más...



             EUPOC 2011, Biobased Polymers and Related Biomaterials




Abril 2011                                                                                                                 Página 17
Nanomedicina
             Publicada en NanoForum.org-Events, 04/18/2011.

             The aims of this Conference are to review the present state of research in the area of biobased/biorelated polymers,
             and to provide a forum for discussion of future progress and prospect. Chemistry, physics and application of
             biobased/biorelated polymers and polymeric biomaterials will be covered.
             Fecha: 29 May 2011 - 03 June 2011. Lugar: Gargnano, Italy.

                  ver más...



             Biomedical Applications in Nanotechnology
             Publicada en NanoMicroClub - Events, 04/18/2011.

             This workshop will provide an overview of some of the latest developments in applying nanotechnology to a range of
             important medical and lifescience applications including biosensing, clinical diagnostics, medical imaging,
             regenerative medicine and drug delivery.
             Fecha: 26 May 2011. Lugar: Glasgow, UK

                  ver más...



             NanoBio-Europe 2011
             Publicada el 04/18/2011.

             The 7th NanoBio-Europe conference will be hosted in Cork (Ireland), showcasing the latest international
             developments in nanobiotechnology, and providing a platform to facilitate interdisciplinary communications, new
             collaborations for delegates from academic, industrial and clinical backgrounds.
             Fecha: 21 - 23 June 2011. Lugar: Cork, Ireland.

                  ver más...



             III Simposio sobre Nanotecnologías CINVESTAV/Sigma Aldrich
             Publicada el 04/18/2011.

             Nanotecnologías en Biología, Química y
             Ciencias de Materiales.
             Fecha: 11 y 12, mayo 2011. Lugar: México DF, México.

                  ver más...



             Conferencia Internacional IMMUNONET: Las Nuevas Tendencias en
             Inmunoterapia




Abril 2011                                                                                                              Página 18
Nanomedicina
             Publicada el 04/18/2011.

             Coincidiendo con su 5ª reunión, la red de Inmunoterapia IMMUNONET ha organizado un taller sobre las nuevas
             tendencias en Inmunoterapia.
             Fecha: 20 May 2011. Lugar: Majadahonda, Madrid, Spain.

                  ver más...



             Nanotech China
             Publicada el 04/18/2011.

             Prestigious professors and scholars from Chinese National Nano Center and Chinese Society of Micronano
             Technology, Many world-known companies will discuss and address on the most recent research results on
             micronano technology, and dissertations on the most advanced studying equipment will also be given by world-
             famous equipment suppliers.
             Fecha: 07 - 09 June 2011. Lugar: Shanghai, China.

                  ver más...



             ARTÍCULOS-CIENTÍFICOS
             Artículos científicos publicados este mes
             Publicada el 04/30/2011.

             Fuente: Scopus




Abril 2011                                                                                                       Página 19
Nanomedicina
             Principales temas tratados en los artículos científicos del mes
             Publicada el 04/30/2011.

             Fuente: Scopus




             Principales entidades con publicaciones este mes
             Publicada el 04/30/2011.

             Fuente: Scopus




Abril 2011                                                                     Página 20
Nanomedicina
             Principales investigadores que publicaron este mes
             Publicada el 04/30/2011.

             Fuente: Scopus




             Balancing forces: architectural control of mechanotransduction
             Publicada en Nanomedicine Research Publicaciones, 04/28/2011.

             Autor: Dufort CC. Resumen: All cells exist within the context of a three-dimensional microenvironment in which they
             are exposed to mechanical and physical cues. These cues can be disrupted through perturbations to
             mechanotransduction, from the nanoscale-level to the tissue-level, which compromises tensional homeostasis to
             promote pathologies such as cardiovascular disease and cancer.

                  ver más...



             Supramolecular self-assembly of biopolymers with carbon
             nanotubes for biomimetic...
             Publicada en RSC - Nanoscale latest articles, 04/26/2011.

             Autor: Luhua Lu. Resumen: Biopolymers are important natural multifunctional macromolecules for biomimetic and
             bio-inspired advanced functional material design. They are not only simple dispersants for carbon nanotube
             stabilization as they have been found to have specific interactions with carbon nanotubes.


                  ver más...




Abril 2011                                                                                                             Página 21
Nanomedicina
             Dual temperature/pH-sensitive drug delivery of poly... nanogels
             Publicada el 04/26/2011.

             Autor: Xiong W. Resumen: In this paper, a dual temperature/pH-sensitive poly(N-isopropylacrylamide-co-acrylic acid)
             nanogel (PNA) was prepared and utilized as a drug carrier. The anti-cancer drug doxorubicin (DOX) was covalent
             bound to PNA via an acid-labile hydrazone linkage.

                  ver más...



             Positive potential operation of a cathodic... immunosensor for
             cancer biomarker detection
             Publicada el 04/22/2011.

             Autor: Xu S. Resumen: In this work, we report a cathodic electrogenerated chemiluminescence (ECL) of luminol at a
             positive potential (ca. 0.05 V vs Ag/AgCl) with a strong light emission on the graphene-modified glass carbon
             electrode.

                  ver más...



             Intracellular pH sensing using p-aminothiophenol functionalized
             gold nanorods...
             Publicada el 04/22/2011.

             Autor: Zong S. Resumen: We report an intracellular pH sensor based on surface enhanced Raman scattering (SERS)
             using the hydrochloric acid (HCl) treated gold nanorods (GNRs) as the SERS substrates and p-aminothiophenol
             (pATP) as the Raman reporter.

                  ver más...



             Quantum dot-aptamer nanoprobes for recognizing and labeling
             influenza A virus particles
             Publicada el 04/21/2011.

             Autor: Cui ZQ. Resumen: The fluorescence labeling of viruses is a useful technology for virus detection and imaging.
             By combining the excellent fluorescence properties of quantum dots (QDs) with the high affinity and specificity of
             aptamers, we constructed a QD-aptamer probe.

                  ver más...




Abril 2011                                                                                                              Página 22
Nanomedicina
             Lithography-based nanoelectrochemistry
             Publicada el 04/21/2011.

             Autor: Rassaei L. Resumen: Lithographically fabricated nanostructures appear in an increasingly wide range of
             scientific fields, and electroanalytical chemistry is no exception. This article introduces lithography methods and
             provides an overview of the new capabilities and electrochemical phenomena that can emerge in nanostructures.


                  ver más...



             Transport of single cells using an actin bundlemyosin
             bionanomotor transport system
             Publicada en IOPscience: latest papers, 04/19/2011.

             Autor: Hideyo Takatsuki. Resumen: The potential of using actin bundles for the transport of liposomes and single
             cells across myosin-coated surfaces is investigated. Compared to that observed with filamentous actin, the liposome
             transport using actin bundles was more linear in nature and able to occur over longer distances.


                  ver más...



             DNA origami with complex curvatures in three-dimensional space
             Publicada en Nanomedicine Research Publicaciones, 04/18/2011.

             Autor: Han D. Resumen: We present a strategy to design and construct self-assembling DNA nanostructures that
             define intricate curved surfaces in three-dimensional (3D) space using the DNA origami folding technique. Double-
             helical DNA is bent to follow the rounded contours of the target object, and potential strand crossovers are
             subsequently identified.

                  ver más...



             Biostability of y-Fe2O3 nano particles ..cytotoxicity assays on
             various tumor cell lines
             Publicada en Virtual Journal of Nanotechnology Environment, Health and Safety, 04/18/2011.

             Autor: Lee KJ. Resumen: This study examined the cytotoxic effects of the y-Fe2O3 magnetic nanoparticles (GMNs)
             on a range of tumor cell lines.

                  ver más...




Abril 2011                                                                                                             Página 23
Nanomedicina
             Activation of neural and pluripotent stem cell signatures...
             Publicada el 04/18/2011.

             Autor: J Holmberg. Resuemn: The presence of stem cell characteristics in glioma cells raises the possibility that
             mechanisms promoting the maintenance and self-renewal of tissue specific stem cells have a similar function in
             tumor cells.

                  ver más...



             Controlled growth and differentiation of MSCs on grooved films
             assembled ...
             Publicada el 04/18/2011.

             Autor: Zhu H. Resumen: The search for a cell-supporting scaffold with controlled topography and surface chemistry is
             a constant topic within tissue engineering. Here we have employed M13 phages, which are genetically modifiable
             biological nanofibers non-toxic to human beings, to form films for supporting the growth of mesencymal stem cells
             (MSCs).

                  ver más...



             Validation of the calibrated thrombin generation test (cTGT)...
             Publicada el 04/18/2011.

             Autor: Laloy J. Resumen: In this study, a preclinical toxicological screening assay was validated and guidelines to
             evaluate the potential impact of nanoparticles (NPs) on blood coagulation are provided.

                  ver más...



             Drug delivery: One nanoparticle, one kill
             Publicada el 04/18/2011.

             Autor: Darrell J. Resumen: By wrapping a ligand-functionalized lipid membrane around a silica core, nanoparticles
             with a fluid surface are created. These combine unprecedented specificity in binding to cancer cells with the
             combinatorial delivery of drug cocktails.

                  ver más...



             Specific penetration and accumulation of a homing peptide within
             atherosclerotic plaques




Abril 2011                                                                                                              Página 24
Nanomedicina
             Publicada el 04/18/2011.

             Autor: J Hamzah. Resumen: The ability to selectively deliver compounds into atherosclerotic plaques would greatly
             benefit the detection and treatment of atherosclerotic disease. We describe such a delivery system based on a 9-
             amino acid cyclic peptide, LyP-1. LyP-1 was originally identified as a tumor-homing peptide...


                  ver más...



             Application of fiber optic ATR-FTIR methods.. for therapeutic
             delivery systems
             Publicada el 04/18/2011.

             Autor: CL McFearin. Resumen: A fiber optic coupled ATR-FTIR spectroscopy technique was applied to the study of
             two different therapeutic delivery systems, acid degradable hydrogels and nanoparticles. Real time exponential
             release of a model protein, human serum albumin (HSA)...

                  ver más...



             Preclinical screening of anti-HER2 nanobodies for molecular
             imaging of breast cancer
             Publicada el 04/18/2011.

             Autor: I Vaneycken. Resumen: Accurate determination of tumor human epidermal growth factor receptor 2 (HER2)-
             status in breast cancer patients is possible via noninvasive imaging, provided adequate tracers are used. In this
             study, we describe the generation of a panel of 38 nanobodies, small HER2-binding fragments that are derived from
             heavy-chain-only antibodies raised in an immunized dromedary.

                  ver más...



             SiRNA delivery with exosome nanoparticles
             Publicada el 04/18/2011.

             Autor: JG van den Boorn. Resumen: A natural system for ferrying RNA between cells is used to transport siRNA to
             the mouse brain.

                  ver más...



             Reactions inside nanoscale protein cages




Abril 2011                                                                                                           Página 25
Nanomedicina
             Publicada en RSC - Nanoscale latest articles, 04/03/2011.

             Autor: Saskia A. Resumen: Chemical reactions are traditionally carried out in bulk solution, but in nature confined
             spaces, like cell organelles, are used to obtain control in time and space of conversion. One way of studying these
             reactions in confinement is the development and use of small reaction vessels dispersed in solution, such as vesicles
             and micelles.

                  ver más...



             NORMATIVAS
             CEN ISO/TS 13830:2011
             Publicada en European Committee for Standardization (CEN) , 04/18/2011.

             Guidance on the labelling of manufactured nano-objects and products containing manufactured nano-objects


                  ver más...



             Nanoscale carbon toxicity testing proposal submitted to EPA
             Publicada en ANSI - Nanotechnology Law Report, 04/07/2011.

             The NanoSafety Consortium for Carbon just submitted a proposed toxicity testing agreement to EPA under Section 4
             of the Toxic Substances Control Act covering a range of nanoscale materials including multi-walled carbon
             nanotubes, double-walled carbon nanotubes, single-walled carbon nanotubes, and graphene.


                  ver más...



             ASTM WK32796 - New Test Method
             Publicada en ASTM International's Committee E56 on Nanotechnology New Workitems, 04/07/2011.

             New test method for measurement of airborne metal and metal oxide nanoparticle surface area in inhalation
             exposure chambers using gas adsorption.

                  ver más...




Abril 2011                                                                                                               Página 26
Nanomedicina
             INFORMES Y OTRAS
             Molecular Diagnostics in Cancer Testing
             Publicada en Biotechnology Market Research Reports, 04/30/2011.

             This TriMark Publications report describes the specific segment of the in vitro diagnostics (IVD) market known as
             molecular diagnostics (MD), with a specialization in the MD tests for cancer. In the current medical diagnostics
             market, molecular diagnostics for cancer testing offers one of the brightest areas for growth and innovation.


                  ver más...



             Market Analyst Dissects Global Nano-medicine Market
             Publicada en European Platform of Nanomedicine Presentaciones, 04/28/2011.

             A recent RNCOS research report titled, Nanotechnology Market Forecast to 2013, states that the global
             nanomedicine market is estimated to grow at a CAGR of 13% in 2009 through 2013.

                  ver más...



             Ethical and Societal Aspects of Nanotechnology Enabled ICT and
             Security Technologies
             Publicada en Nanoforum.org - Reports, 04/28/2011.

             In this report, public debates and literature on ethical and societal aspects of nanotechnology in ICT and security, and
             civil-military dual use aspects of nanotechnology are discussed. The main aim is to identify new or persistent issues
             in these debates that merit the attention of policy makers responsible for nanotechnology in Europe.


                  ver más...



             Nanotechnology Research Directions for Societal Needs in 2020
             Retrospective and Outlook
             Publicada en Australian Research Council Nanotechnology Network (ARCNN) Publications, 04/18/2011.

             The National Science Foundation(NSF) and the World Technology Evaluation Center(WTEC) have conducted a
             study on Nanotechnology Research directions titled "Nanotechnology Research Directions for Societal Needs in 2020
             Retrospective and Outlook.


                  ver más...




Abril 2011                                                                                                                  Página 27
Nanomedicina
             Double-walled carbon nanotubes for medical imaging by MRI and
             other biomedical applications
             Publicada el 04/18/2011.

             Tesis doctoral. Carbon nanotubes (CNT) represent a great hope for different biomedical applications (drug delivery,
             controlled release, vaccines, medical imaging). The potential toxicity of CNT should however not be ignored and the
             Nanocomposites and Carbon Nanotubes (NCN) team at the CIRIMAT has participated as one of the leaders in this
             field (3 PhD students already, coordination of a national "ANR" programme, participation to the CARBIO Marie Curie
             RTN, etc.).

                  ver más...



             Design of biocompatible dendrimers for cancer diagnosis and
             therapy: current status and future perspectives
             Publicada el 04/18/2011.

             In the past decade, nanomedicine with its promise of improved therapy and diagnostics has revolutionized
             conventional health care and medical technology. Dendrimers and dendrimer-based therapeutics are outstanding
             candidates in this exciting field as more and more biological systems have benefited from these starburst molecules.


                  ver más...




Abril 2011                                                                                                              Página 28

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Boletín Nanomedicina Abril 2011

  • 1. Abril 2011 Boletín Nanomedicina generado por VIGIALE, IALE Tecnología.
  • 2. HIDDEN TEXT TO MARK THE BEGINNING OF THE TABLE OF CONTENTS INDICE NOTICIAS 1. NANO-systems to accelerate recovery after surgery without side effects 2 2. Nanotechnology for the treatment of coronary in stent restenosis: A clinical perspective 2 3. Sandia and UNM lead effort to destroy cancers 2 4. Nanoscience may hold key to surgical recovery 2 5. Scientists engineer nanoscale vaults to encapsulate 'nanodisks' for drug delivery 3 6. Promising data demonstrating the anti-tumor activity of a novel cancer target 3 7. Stanford research moves nanomedicine one step closer to reality 3 8. Pediatric Center Focuses on Nano-Medicine for Pediatric Care 3 9. IBM nanomedicine breakthrough to aid antibiotics 4 10. Nanofiber spheres show promise for knee cartilage repair 4 11. Nanotech device identifies cancer and HIV 4 12. Nanotechnology vehicle speeds numbing of topical lidocaine 4 13. Injectable gel could spell relief for arthritis sufferers 4 14. DNA stretching: new technique to detect illnesses 5 15. Pre-clinical results for oral delivery of the anti-cancer drug 5 16. New DNA nanoforms take shape 5 17. NCKU and NRC made innovative cancer diagnostic and treatment discoveries 5 18. Nanofiber spheres carrying cells injected into wounds to grow tissue 6 19. First look at the mechanics of membrane proteins 6 20. Nanoscience used to identify cancer drug effectiveness 6 21. The world's smallest wedding rings 6 22. Hand-held NMR instrument yields rapid analysis of human tumors 7 23. Nanoparticles enhance detection of circulating tumor cells 7 24. 'Good cholesterol' nanoparticles seek and destroy cancer cells 7 25. Study develops new approaches for sorting out complexities of cancer cells 7 26. Chemical engineers at UCSB design molecular probe to study disease 8 27. Personalized therapies for inflammation 8 28. Study ways to improve treatment of inflammatory bowel disease 8 29. La batalla entre microRNAs y oncogenes 8 PATENTES 30. Patentes publicadas este mes 9 31. Origen de los principales actores del mes 9 32. Principales temas tratados en las patentes del mes 10 33. Principales titulares de las patentes del mes 10 34. Principales inventores que patentaron este mes 11
  • 3. INDICE 35. US20110097401A1: Methods for treating gastrointestinal disorders 11 36. US20110091560A1: Compositions of nanoparticles and methods of making the same 11 37. US20110091373A1: PAA nanoparticles for enhancement of tumor imaging 12 38. US20110097277A1: Particles coated with zwitterionic polymers 12 39. US20110093020A1: Poly-porous hollow screw for target delivery of growth factors... 12 40. WO2011050357A2: Protein arginine deiminase inhibitors for rheumatoid arthritis and cancer 12 41. US20110097377A1: Methods and devices for correcting spinal deformity... 13 42. US20110093089A1: Electronically controlled prosthetic system 13 43. US20110097420A1: Cement products and methods of making and using the same 13 44. US20110091353A1: Methods for sterilizing tissue 13 45. US20110098558A1: System and method for use of nanoparticles imaging and diagnosis 14 46. WO2011048493A1: Coated capsules and tablets of fatty acid oil mixture 14 EVENTOS, CURSOS Y SEMINARIOS 47. Smart Polymer Systems 2011 14 48. EuroNanoForum 2011 14 49. European Perspectives in Personalised Medicine 15 50. 6th Intl Congress of Nano Bio Clean Tech 15 51. 4th European-Conference for Clinical Nanomedicine 15 52. Nanotech Conference and Expo 2011 15 53. Nanomedicine 2011 - 3rd ESF Summer School 16 54. Greener Nano 2011 16 55. EuroNanoForum 2011 16 56. European Perspectives in Personalised Medicine 16 57. Safety issues of Nanomaterials along their life cycle Symposium 16 58. 7th International Dendrimer Symposium 17 59. Biomedical Nanotechnology 17 60. Nanomaterials 2011 17 61. EUPOC 2011, Biobased Polymers and Related Biomaterials 17 62. Biomedical Applications in Nanotechnology 18 63. NanoBio-Europe 2011 18 64. III Simposio sobre Nanotecnologías CINVESTAV/Sigma Aldrich 18 65. Conferencia Internacional IMMUNONET: Las Nuevas Tendencias en Inmunoterapia 18 66. Nanotech China 19 ARTÍCULOS- CIENTÍFICOS
  • 4. INDICE 67. Artículos científicos publicados este mes 19 68. Principales temas tratados en los artículos científicos del mes 20 69. Principales entidades con publicaciones este mes 20 70. Principales investigadores que publicaron este mes 21 71. Balancing forces: architectural control of mechanotransduction 21 72. Supramolecular self-assembly of biopolymers with carbon nanotubes for biomimetic... 21 73. Dual temperature/pH-sensitive drug delivery of poly... nanogels 22 74. Positive potential operation of a cathodic... immunosensor for cancer biomarker detection 22 75. Intracellular pH sensing using p-aminothiophenol functionalized gold nanorods... 22 76. Quantum dot-aptamer nanoprobes for recognizing and labeling influenza A virus particles 22 77. Lithography-based nanoelectrochemistry 23 78. Transport of single cells using an actin bundlemyosin bionanomotor transport system 23 79. DNA origami with complex curvatures in three-dimensional space 23 80. Biostability of y-Fe2O3 nano particles ..cytotoxicity assays on various tumor cell lines 23 81. Activation of neural and pluripotent stem cell signatures... 24 82. Controlled growth and differentiation of MSCs on grooved films assembled ... 24 83. Validation of the calibrated thrombin generation test (cTGT)... 24 84. Drug delivery: One nanoparticle, one kill 24 85. Specific penetration and accumulation of a homing peptide within atherosclerotic plaques 24 86. Application of fiber optic ATR-FTIR methods.. for therapeutic delivery systems 25 87. Preclinical screening of anti-HER2 nanobodies for molecular imaging of breast cancer 25 88. SiRNA delivery with exosome nanoparticles 25 89. Reactions inside nanoscale protein cages 25 NORMATIVAS 90. CEN ISO/TS 13830:2011 26 91. Nanoscale carbon toxicity testing proposal submitted to EPA 26 92. ASTM WK32796 - New Test Method 26 INFORMES Y OTRAS PUBLICACIONES 93. Molecular Diagnostics in Cancer Testing 27 94. Market Analyst Dissects Global Nano-medicine Market 27 95. Ethical and Societal Aspects of Nanotechnology Enabled ICT and Security Technologies 27 96. Nanotechnology Research Directions for Societal Needs in 2020 Retrospective and Outlook 27 97. Double-walled carbon nanotubes for medical imaging by MRI and other biomedical applications 28 98. Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future ... 28
  • 5.
  • 6. Nanomedicina NOTICIAS NANO-systems to accelerate recovery after surgery without side effects Publicada en Azonano - Noticias sobre Nanomedicina, 04/29/2011. By Cameron ChaiThe University of York research team at the Department of Chemistry has created artificial molecules that can attach the chemical drug heparin that could replace protamine. ver más... Nanotechnology for the treatment of coronary in stent restenosis: A clinical perspective Publicada en Nanotechnology Now, 04/28/2011. Coronary in stent restenosis remains a significant limitation to the long term efficacy of coronary artery stent placement. In this review the authors review the pathophysiology of coronary instent restenosis, together with an overview of the current treatment modalities. ver más... Sandia and UNM lead effort to destroy cancers Publicada en Nanotechwire.com - Bio/Medicine, 04/28/2011. Melding nanotechnology and medical research, Sandia National Laboratories, the University of New Mexico, and the UNM Cancer Research and Treatment Center have produced an effective strategy that uses nanoparticles to blast cancerous cells with a mélange of killer drugs. ver más... Nanoscience may hold key to surgical recovery Publicada en Science Daily - Nanomedicina, 04/28/2011. Researchers from the University of York's Department of Chemistry have developed synthetic molecules capable of binding the chemical drug heparin, which they believe may provide an alternative to protamine. ver más... Abril 2011 Página 2
  • 7. Nanomedicina Scientists engineer nanoscale vaults to encapsulate 'nanodisks' for drug delivery Publicada en Nanotechwire.com - Drug Delivery, 04/28/2011. In recent years, researchers have grappled with the challenge of administering therapeutics in a way that boosts their effectiveness by targeting specific cells in the body while minimizing their potential damage to healthy tissue. ver más... Promising data demonstrating the anti-tumor activity of a novel cancer target Publicada el 04/22/2011. Tekmira Pharmaceuticals Corporation, a leading developer of RNA interference (RNAi) therapeutics, announced today that promising preclinical data from its collaboration with the National Cancer Institute (NCI) has been published in Oncogene, one of the world's leading cancer journals. ver más... Stanford research moves nanomedicine one step closer to reality Publicada el 04/20/2011. A class of engineered nanoparticles gold-centered spheres smaller than viruses has been shown safe when administered by two alternative routes in a mouse study led by investigators at the Stanford University School of Medicine. This marks the first step up the ladder of toxicology studies that, within a year and a half, could yield to human trials of the tiny agents for detection of colorectal and possibly other cancers. ver más... Pediatric Center Focuses on Nano-Medicine for Pediatric Care Publicada el 04/18/2011. Researchers at the Center for Pediatric Nanomedicine (CPN) will design specific, nanoparticles in an endeavor to treat pediatric illnesses. Focus will be on pediatric heart disease and thrombosis, infectious diseases, cancer, sickle cell disease and cystic fibrosis. ver más... Abril 2011 Página 3
  • 8. Nanomedicina IBM nanomedicine breakthrough to aid antibiotics Publicada el 04/18/2011. IBM researchers and scientists from the Institute of Bioengineering and Nanotechnology on Sunday unveiled a nanomedicine breakthrough biodegradable nanoparticles that make antibiotics physically attracted to infected cells. ver más... Nanofiber spheres show promise for knee cartilage repair Publicada en Nanomedicine Research - News, 04/18/2011. Using injectable hollow, biodegradable nanofiber spheres as cell carriers is likely to repair knee cartilage more effectively than current methods, said US researchers in a paper published online in Nature Materials this week. ver más... Nanotech device identifies cancer and HIV Publicada en BSI -Nanotechnology news, 04/18/2011. A new device has been created by scientists from Harvard University and the Massachusetts Institute of Technology (MIT) that is capable of detecting cancer cells and indicators of HIV in blood. Using carbon nanotubes to create posts measuring 30 microns in diameter, the team has developed technology that is capable of catching tiny objects flowing through a microfluidic system. ver más... Nanotechnology vehicle speeds numbing of topical lidocaine Publicada en Nanotechnology Now, 04/18/2011. A 4% topical lidocaine cream with a nanotechnology-based vehicle in development provided superior pain relief before facial filler injections, compared with the most commonly-used topical anesthetic cream, according to patient and physician ratings in two split-face studies. ver más... Injectable gel could spell relief for arthritis sufferers Abril 2011 Página 4
  • 9. Nanomedicina Publicada en Nanotechwire.com - Bio/Medicine, 04/18/2011. Researchers from Brigham and Womens Hospital have developed a potentially new way to treat arthritis. Here their new gel (red, with yellow rectangles representing encapsulated medicine) is injected into an arthritic joint. There enzymes (black image) associated with arthritis break down the biodegradable gel, releasing the medicine. ver más... DNA stretching: new technique to detect illnesses Publicada en Science Daily - Nanomedicina, 04/18/2011. Scientists are making DNA sequences being passed through nanochannels a thousand times thinner than a human hair to the point that they take on the form of diminutive spaghetti. This is an innovative technique, known as DNA stretching, and is one of the lines of research in which CIC microGUNE is working, and about which they have already published two scientific articles and are shortly to apply for a patent. ver más... Pre-clinical results for oral delivery of the anti-cancer drug Publicada en Nanotechwire.com - Drug Delivery, 04/18/2011. Yissum Research Development Company Ltd., the technology transfer company of the Hebrew University of Jerusalem, announced today successful pre-clinical data of oral delivery of Docetaxel, an anti-cancer drug, utilizing a novel nanotechnology platform. ver más... New DNA nanoforms take shape Publicada el 04/18/2011. Miniature architectural forms have been constructed through a revolutionary technique known as DNA origami. Now, Hao Yan, Yan Liu and their colleagues at Arizona State University's Biodesign Institute have expanded the capability of this method to construct arbitrary, two and three-dimensional shapes, mimicking those commonly found in nature. ver más... NCKU and NRC made innovative cancer diagnostic and treatment discoveries Abril 2011 Página 5
  • 10. Nanomedicina Publicada el 04/18/2011. A Taiwanese research team led by Prof. Dar-Bin Shieh of Institute of Oral Medicine in Medical College at National Cheng Kung University (NCKU) has partnered with a research group led by Dr. Dennis Whitefield from National Research Council (NRC) of Canada to develop innovative cancer diagnostic and treatment technologies. ver más... Nanofiber spheres carrying cells injected into wounds to grow tissue Publicada el 04/18/2011. For the first time, scientists have made star-shaped, biodegradable polymers that can self-assemble into hollow, nanofiber spheres, and when the spheres are injected with cells into wounds, these spheres biodegrade, but the cells live on to form new tissue. ver más... First look at the mechanics of membrane proteins Publicada el 04/18/2011. In two new studies, researchers provide the first detailed view of the elaborate chemical and mechanical interactions that allow the ribosome - the cell's protein-building machinery - to insert a growing protein into the cellular membrane. ver más... Nanoscience used to identify cancer drug effectiveness Publicada el 04/18/2011. The effectiveness of treatments for cancer could be better assessed using nanotechnology, it has been claimed. A scientist in Indiana in the US has been experimenting with nanopolymers and has discovered they could help to determine whether or not drugs are reaching the intended site. ver más... The world's smallest wedding rings Publicada el 04/18/2011. Prof Alexander Heckel and his doctoral student Thorsten Schmidt from the "Cluster of Excellence for Macromolecular Complexes" at Goethe University were able to create two rings of DNA only 18 nanometers in size, and to interlock them like two links in a chain. Such a structure is called catenan, a term derived from the Latin word catena (chain). Abril 2011 Página 6
  • 11. Nanomedicina ver más... Hand-held NMR instrument yields rapid analysis of human tumors Publicada el 04/18/2011. Using a handheld molecular imaging device in combination with magnetic nanoparticles and a smartphone, a team of investigators from the Massachusetts General Hospital and Harvard Medical School has developed a fast, portable and potentially inexpensive method of detecting cancer from human biopsy samples. ver más... Nanoparticles enhance detection of circulating tumor cells Publicada el 04/18/2011. Circulating tumor cells (CTCs), shed into the blood stream by tumors, are thought to provide a means of detecting cancer early, conducting a preliminary assessment of which anticancer agents might prove most effective at treating a given patient, and assessing whether a chosen therapy is working. ver más... 'Good cholesterol' nanoparticles seek and destroy cancer cells Publicada el 04/18/2011. High-density lipoprotein's hauls excess cholesterol to the liver for disposal, but new research suggests "good cholesterol" can also act as a special delivery vehicle of destruction for cancer. ver más... Study develops new approaches for sorting out complexities of cancer cells Publicada el 04/18/2011. New drugs that specifically target the mutated genes responsible for cancer growth have shown great success in extending the lives of patients, with far fewer side effects than conventional anti-cancer therapies. Unfortunately, many patients become resistant to these drugs due to secondary mutations. ver más... Abril 2011 Página 7
  • 12. Nanomedicina Chemical engineers at UCSB design molecular probe to study disease Publicada el 04/18/2011. Chemical engineers at UC Santa Barbara expect that their new process to create molecular probes may eventually result in the development of new drugs to treat cancer and other illnesses. ver más... Personalized therapies for inflammation Publicada el 04/18/2011. Scientists at Barts and The London School of Medicine and Dentistry and Harvard Medical School, Boston have found a way of mimicking the body's natural mechanism of fighting inflammation. During inflammation cells release very small particles termed 'microparticles' that retain features of their parent cell. ver más... Study ways to improve treatment of inflammatory bowel disease Publicada el 04/18/2011. CEA-Leti today announced a new project designed to develop a novel nanocarrier-based approach to improve the treatment of inflammatory bowel disease, and increasingly common condition in Europe. ver más... La batalla entre microRNAs y oncogenes Publicada el 04/18/2011. La prestigiosa revista Blood publica en su último numero un artículo del Grupo de División Celular y Cáncer del CNIO, que dirige Marcos Malumbres, en el que se da cuenta de la batalla que libran los microRNAs -pequeños fragmentos de RNA- por modular y controlar la actividad de determinados oncogenes y evitar así que las células se conviertan en cancerosas. ver más... Abril 2011 Página 8
  • 13. Nanomedicina PATENTES Patentes publicadas este mes Publicada el 04/30/2011. Fuente: Espacenet, USPTO Origen de los principales actores del mes Publicada el 04/30/2011. Fuente: Espacenet, USPTO Abril 2011 Página 9
  • 14. Nanomedicina Principales temas tratados en las patentes del mes Publicada el 04/30/2011. Fuente: Espacenet, UPSTO Principales titulares de las patentes del mes Publicada el 04/30/2011. Fuente: Espacenet, UPSTO Abril 2011 Página 10
  • 15. Nanomedicina Principales inventores que patentaron este mes Publicada el 04/30/2011. Fuente: Especenet, USPTO US20110097401A1: Methods for treating gastrointestinal disorders Publicada el 04/29/2011. Inventor: Phillips Elaine. Titular: Meritage Pharma Inc (US). Resumen: Provided herein are compositions and formulations suitable for the treatment of gastrointestinal disorders. Also provided are methods for treating, preventing, or alleviating disorders of the gastrointestinal tract, for example, those involving the esophagus. ver más... US20110091560A1: Compositions of nanoparticles and methods of making the same Publicada el 04/29/2011. Inventor: Smith Jeff (US). Titular: Burhnam Inst Medical Research (US). Resumen: Disclosed herein are compositions of nanoparticles. In some embodiments, the nanoparticles are Janus particles, where each particle includes a first component and second component that are exposed to the surface of the particle. ver más... Abril 2011 Página 11
  • 16. Nanomedicina US20110091373A1: PAA nanoparticles for enhancement of tumor imaging Publicada el 04/29/2011. Inventor: Pandey Ravindra K. Titulares: Health Research Inc (US), Unic New York State Res Found (US); Univ Michigan (US). Resumen: A composition comprising PAA nanoparticles containing a post loaded tetrapyrollic photosensitizer and an imaging agent and methods for making and using same. ver más... US20110097277A1: Particles coated with zwitterionic polymers Publicada el 04/29/2011. Inventor: Jiang Shaoyi. Titular: Univ Washington (US). Resumen: Nanoparticles zwitterionic polymers grafted thereto or grafted therefrom, and methods for making and using the nanoparticles. Zwitterionic nanogels, and methods for making and using the nanogels. ver más... US20110093020A1: Poly-porous hollow screw for target delivery of growth factors... Publicada el 04/29/2011. Inventor y Titular: Wu Yangguan (US). Resumen: Present invention depicts a poly-porous (micropore) hollow screws as diffusion chamber filled with core matrix for targeted delivery of growth factors and bone marrow stem cells. The screws comprise at least two parts: the distal part of the screw consists of the tip of the screw made of poly porous material and hollow inside proximally. ver más... WO2011050357A2: Protein arginine deiminase inhibitors for rheumatoid arthritis and cancer Publicada el 04/29/2011. Inventor: Thompson Paul R. Titular: Univ South Carolina (US). Resumen: In accordance with certain embodiments of the present disclosure, a self-assembling biodegradable nanoparticle is provided. The nanoparticle includes Cys-Val- Val-Val-Val-Val-Val-Lys-Lys conjugated with a synthetic polymer and has a diameter of from about 50 nm to about 150 nm. ver más... Abril 2011 Página 12
  • 17. Nanomedicina US20110097377A1: Methods and devices for correcting spinal deformity... Publicada el 04/29/2011. Inventor y Titular: Serhan Hassan (US). Resumen: A method of correcting spinal deformity, which includes locating pharmaceutical-loaded implants adjacent to targeted spinal growth plates, and then eluting the pharmaceutical onto the growth plates. Preferably, the method involves correcting spinal deformity by simply inserting a pharmaceutical- eluting pedicle screw onto the concave side of a scoliotic curve. ver más... US20110093089A1: Electronically controlled prosthetic system Publicada el 04/29/2011. Inventor y Titular: Martin James J (US). Resumen: A prosthetic joint system for users comprising a housing having an interior cavity, a center axis in said interior cavity, and an attachment means for fixedly connecting said housing to said user... ver más... US20110097420A1: Cement products and methods of making and using the same Publicada el 04/29/2011. Inventor: Lin Juchui Ray. Titular: Angstrom Medica (US). Resumen: Disclosed are cement products, methods of forming cement using the cement product, and methods of using the cement product in orthopedic and dental applications.... cement product includes a first component comprising a polymerizable resin .....optionally, the cement product includes a bioactive component to promote bone formation. ver más... US20110091353A1: Methods for sterilizing tissue Publicada el 04/29/2011. Inventor y Titular: Burgess Wilson (US). Resumen: Methods are disclosed for sterilizing tissue to reduce the level of one or more active biological contaminants or pathogens therein, such as viruses, bacteria, yeasts, molds, fungi, prions or similar agents responsible, alone or in combination, for TSEs and/or single or multicellular parasites. The methods involve sterilizing one or more tissues with irradiation. ver más... Abril 2011 Página 13
  • 18. Nanomedicina US20110098558A1: System and method for use of nanoparticles imaging and diagnosis Publicada el 04/29/2011. Inventor: Weaver John B. Titular: Dartmouth College The Trustees (US). Resumen: A method for diagnosing certain types of cancers provides a nanoparticle agent to be uptaken by cancer cells for diagnosis and treatment of certain cancers. A compound containing nanoparticles is directed toward a tumor site, and then a predetermined time period passes to allow the nanoparticles to be uptaken by the cancer cells. ver más... WO2011048493A1: Coated capsules and tablets of fatty acid oil mixture Publicada el 04/29/2011. Inventor: Klaveness JO Erik Johnsrud (NO). Titular: Pronova Biopharma Norge AS (NO). Resumen: Compositions comprising a fatty acid oil mixture and at least one free fatty acid in a coated capsule or a coated tablet form suitable for oral administration, and methods of use thereof, are disclosed. ver más... EVENTOS, CURSOS Y SEMINARIOS Smart Polymer Systems 2011 Publicada en AzoNanotechnology-Eventos, 04/28/2011. The conference aims to provide a comprehensive overview of the current state-of-the-art in the field and demonstrate, via a range of case studies and contributions from leading researchers, how companies might capitalise on this emerging technology. Fecha: May 25 - 26, 2011. Lugar: Mainz, Germany. ver más... EuroNanoForum 2011 Publicada el 04/18/2011. EuroNanoForum is a biannual event supported by the European Commission and organised within the framework of the Presidency of the European Union. Fecha: 30 May -1 June 2011. Lugar: Budapest, Hungary. ver más... Abril 2011 Página 14
  • 19. Nanomedicina European Perspectives in Personalised Medicine Publicada el 04/18/2011. This conference will bring together key stakeholders of the research community and the healthcare sector to identify the developments needed in order to contribute to the research for Personalised Medicine at European and national level, in the frame of the Innovation Union and beyond. Fecha: 12 - 13 May 2011. Lugar: Brussels, Belgium. ver más... 6th Intl Congress of Nano Bio Clean Tech Publicada el 04/18/2011. The conference will gather world class researchers, business executives and engineers from over 30 countries and cover the following topics: Nanomaterials, Nanobiotechnology, Molecular Engineering, Heath Safety Implications, Intellectual Property, Commercialization, Venture capital investment and other related topics. Fecha: June 20, 2011. Lugar: San Francisco, CA, USA. ver más... 4th European-Conference for Clinical Nanomedicine Publicada el 04/18/2011. The conference focuses on clinical application of novel developments innanoscience but also includes industrial topics, the expertise formregulatory authorities and discussion on ethical questions and widerimplications. Fecha: 23 May, 2011. Lugar: Basel, Switzerland. ver más... Nanotech Conference and Expo 2011 Publicada el 04/18/2011. Uniting innovators to bring nanotechnology from laboratory to marketplace. Nanotech 2011 brings together over 5,000 technology and business leaders and experts from academia, government, startups and Fortune 1,000 companies. Fecha: June 13, 2011. Lugar: Boston, MA, USA. ver más... Abril 2011 Página 15
  • 20. Nanomedicina Nanomedicine 2011 - 3rd ESF Summer School Publicada el 04/18/2011. The ESF Summer School Nanomedicine 2011, has been designed to provide an intensive state-of the- art training across all of the sub-disciplines of Nanomedicine, and to foster discussion and exchange of ideas in a relaxed atmosphere. Fecha: June 19-24, 2011. Lugar: Wittenberg, Germany. ver más... Greener Nano 2011 Publicada el 04/18/2011. We will focus on two key research areas: highlight state-of-the-art in materials synthesis and characterization challenges, and discuss biological impacts of nanotechnology. Fecha: May 01 - 03, 2011. Lugar: Cupertino California, USA ver más... EuroNanoForum 2011 Publicada el 04/18/2011. EuroNanoForum is a biannual event supported by the European Commission and organised within the framework of the Presidency of the European Union. Fecha: May 30 - June 01, 2011. Lugar: Budapest, Hungary. ver más... European Perspectives in Personalised Medicine Publicada el 04/18/2011. This conference will bring together key stakeholders of the research community and the healthcare sector to identify the developments needed in order to contribute to the research for Personalised Medicine. Fecha: 12-13 May 2011. Lugar: Square-Brussels Meeting Centre, Brussels ver más... Safety issues of Nanomaterials along their life cycle Symposium Abril 2011 Página 16
  • 21. Nanomedicina Publicada el 04/18/2011. The aim of the Symposium is to discuss about the human and environmental impacts of nanomaterials along their life cycle from their production through their processing, use, and end of life (recycling and/or disposal). Fecha: 4-5 May, 2011. Lugar: Terrassa, Barcelona, Spain. ver más... 7th International Dendrimer Symposium Publicada el 04/18/2011. An average of 300-400 participants attended these symposium from over 30 countries every two years.The symposium focuses on the scientific research, latest developments in technology, synthesis, characterizationand applications. Fecha: June 26 - July 1, 2011. Lugar: Gaithersburg, Maryland, USA. ver más... Biomedical Nanotechnology Publicada en AzoNano-Nanomaterial Courses, 04/18/2011. Biomedical Nanotechnology is a course that investigates key areas in which nanotechnology can benefit biomedical applications, understanding of nanomaterials for various biomedical applications, wet and dry nanotechnology, and basics of nanofabrication. This course also introduces applications such as drug delivery, imaging and diagnostics, and tissue regeneration and engineering. Fecha: Continual. Lugar: online. ver más... Nanomaterials 2011 Publicada en NanoConferences.com, 04/18/2011. NanoMaterials 2011 will feature 2 plenary sessions and 3 parallel sessions with a change in focus from the previous editions. These 3 programme tracks will focus on: Policy, Business & Finance; and Synthesis and production... Fecha: June 07 - 09, 2011. Lugar: London, UK. ver más... EUPOC 2011, Biobased Polymers and Related Biomaterials Abril 2011 Página 17
  • 22. Nanomedicina Publicada en NanoForum.org-Events, 04/18/2011. The aims of this Conference are to review the present state of research in the area of biobased/biorelated polymers, and to provide a forum for discussion of future progress and prospect. Chemistry, physics and application of biobased/biorelated polymers and polymeric biomaterials will be covered. Fecha: 29 May 2011 - 03 June 2011. Lugar: Gargnano, Italy. ver más... Biomedical Applications in Nanotechnology Publicada en NanoMicroClub - Events, 04/18/2011. This workshop will provide an overview of some of the latest developments in applying nanotechnology to a range of important medical and lifescience applications including biosensing, clinical diagnostics, medical imaging, regenerative medicine and drug delivery. Fecha: 26 May 2011. Lugar: Glasgow, UK ver más... NanoBio-Europe 2011 Publicada el 04/18/2011. The 7th NanoBio-Europe conference will be hosted in Cork (Ireland), showcasing the latest international developments in nanobiotechnology, and providing a platform to facilitate interdisciplinary communications, new collaborations for delegates from academic, industrial and clinical backgrounds. Fecha: 21 - 23 June 2011. Lugar: Cork, Ireland. ver más... III Simposio sobre Nanotecnologías CINVESTAV/Sigma Aldrich Publicada el 04/18/2011. Nanotecnologías en Biología, Química y Ciencias de Materiales. Fecha: 11 y 12, mayo 2011. Lugar: México DF, México. ver más... Conferencia Internacional IMMUNONET: Las Nuevas Tendencias en Inmunoterapia Abril 2011 Página 18
  • 23. Nanomedicina Publicada el 04/18/2011. Coincidiendo con su 5ª reunión, la red de Inmunoterapia IMMUNONET ha organizado un taller sobre las nuevas tendencias en Inmunoterapia. Fecha: 20 May 2011. Lugar: Majadahonda, Madrid, Spain. ver más... Nanotech China Publicada el 04/18/2011. Prestigious professors and scholars from Chinese National Nano Center and Chinese Society of Micronano Technology, Many world-known companies will discuss and address on the most recent research results on micronano technology, and dissertations on the most advanced studying equipment will also be given by world- famous equipment suppliers. Fecha: 07 - 09 June 2011. Lugar: Shanghai, China. ver más... ARTÍCULOS-CIENTÍFICOS Artículos científicos publicados este mes Publicada el 04/30/2011. Fuente: Scopus Abril 2011 Página 19
  • 24. Nanomedicina Principales temas tratados en los artículos científicos del mes Publicada el 04/30/2011. Fuente: Scopus Principales entidades con publicaciones este mes Publicada el 04/30/2011. Fuente: Scopus Abril 2011 Página 20
  • 25. Nanomedicina Principales investigadores que publicaron este mes Publicada el 04/30/2011. Fuente: Scopus Balancing forces: architectural control of mechanotransduction Publicada en Nanomedicine Research Publicaciones, 04/28/2011. Autor: Dufort CC. Resumen: All cells exist within the context of a three-dimensional microenvironment in which they are exposed to mechanical and physical cues. These cues can be disrupted through perturbations to mechanotransduction, from the nanoscale-level to the tissue-level, which compromises tensional homeostasis to promote pathologies such as cardiovascular disease and cancer. ver más... Supramolecular self-assembly of biopolymers with carbon nanotubes for biomimetic... Publicada en RSC - Nanoscale latest articles, 04/26/2011. Autor: Luhua Lu. Resumen: Biopolymers are important natural multifunctional macromolecules for biomimetic and bio-inspired advanced functional material design. They are not only simple dispersants for carbon nanotube stabilization as they have been found to have specific interactions with carbon nanotubes. ver más... Abril 2011 Página 21
  • 26. Nanomedicina Dual temperature/pH-sensitive drug delivery of poly... nanogels Publicada el 04/26/2011. Autor: Xiong W. Resumen: In this paper, a dual temperature/pH-sensitive poly(N-isopropylacrylamide-co-acrylic acid) nanogel (PNA) was prepared and utilized as a drug carrier. The anti-cancer drug doxorubicin (DOX) was covalent bound to PNA via an acid-labile hydrazone linkage. ver más... Positive potential operation of a cathodic... immunosensor for cancer biomarker detection Publicada el 04/22/2011. Autor: Xu S. Resumen: In this work, we report a cathodic electrogenerated chemiluminescence (ECL) of luminol at a positive potential (ca. 0.05 V vs Ag/AgCl) with a strong light emission on the graphene-modified glass carbon electrode. ver más... Intracellular pH sensing using p-aminothiophenol functionalized gold nanorods... Publicada el 04/22/2011. Autor: Zong S. Resumen: We report an intracellular pH sensor based on surface enhanced Raman scattering (SERS) using the hydrochloric acid (HCl) treated gold nanorods (GNRs) as the SERS substrates and p-aminothiophenol (pATP) as the Raman reporter. ver más... Quantum dot-aptamer nanoprobes for recognizing and labeling influenza A virus particles Publicada el 04/21/2011. Autor: Cui ZQ. Resumen: The fluorescence labeling of viruses is a useful technology for virus detection and imaging. By combining the excellent fluorescence properties of quantum dots (QDs) with the high affinity and specificity of aptamers, we constructed a QD-aptamer probe. ver más... Abril 2011 Página 22
  • 27. Nanomedicina Lithography-based nanoelectrochemistry Publicada el 04/21/2011. Autor: Rassaei L. Resumen: Lithographically fabricated nanostructures appear in an increasingly wide range of scientific fields, and electroanalytical chemistry is no exception. This article introduces lithography methods and provides an overview of the new capabilities and electrochemical phenomena that can emerge in nanostructures. ver más... Transport of single cells using an actin bundlemyosin bionanomotor transport system Publicada en IOPscience: latest papers, 04/19/2011. Autor: Hideyo Takatsuki. Resumen: The potential of using actin bundles for the transport of liposomes and single cells across myosin-coated surfaces is investigated. Compared to that observed with filamentous actin, the liposome transport using actin bundles was more linear in nature and able to occur over longer distances. ver más... DNA origami with complex curvatures in three-dimensional space Publicada en Nanomedicine Research Publicaciones, 04/18/2011. Autor: Han D. Resumen: We present a strategy to design and construct self-assembling DNA nanostructures that define intricate curved surfaces in three-dimensional (3D) space using the DNA origami folding technique. Double- helical DNA is bent to follow the rounded contours of the target object, and potential strand crossovers are subsequently identified. ver más... Biostability of y-Fe2O3 nano particles ..cytotoxicity assays on various tumor cell lines Publicada en Virtual Journal of Nanotechnology Environment, Health and Safety, 04/18/2011. Autor: Lee KJ. Resumen: This study examined the cytotoxic effects of the y-Fe2O3 magnetic nanoparticles (GMNs) on a range of tumor cell lines. ver más... Abril 2011 Página 23
  • 28. Nanomedicina Activation of neural and pluripotent stem cell signatures... Publicada el 04/18/2011. Autor: J Holmberg. Resuemn: The presence of stem cell characteristics in glioma cells raises the possibility that mechanisms promoting the maintenance and self-renewal of tissue specific stem cells have a similar function in tumor cells. ver más... Controlled growth and differentiation of MSCs on grooved films assembled ... Publicada el 04/18/2011. Autor: Zhu H. Resumen: The search for a cell-supporting scaffold with controlled topography and surface chemistry is a constant topic within tissue engineering. Here we have employed M13 phages, which are genetically modifiable biological nanofibers non-toxic to human beings, to form films for supporting the growth of mesencymal stem cells (MSCs). ver más... Validation of the calibrated thrombin generation test (cTGT)... Publicada el 04/18/2011. Autor: Laloy J. Resumen: In this study, a preclinical toxicological screening assay was validated and guidelines to evaluate the potential impact of nanoparticles (NPs) on blood coagulation are provided. ver más... Drug delivery: One nanoparticle, one kill Publicada el 04/18/2011. Autor: Darrell J. Resumen: By wrapping a ligand-functionalized lipid membrane around a silica core, nanoparticles with a fluid surface are created. These combine unprecedented specificity in binding to cancer cells with the combinatorial delivery of drug cocktails. ver más... Specific penetration and accumulation of a homing peptide within atherosclerotic plaques Abril 2011 Página 24
  • 29. Nanomedicina Publicada el 04/18/2011. Autor: J Hamzah. Resumen: The ability to selectively deliver compounds into atherosclerotic plaques would greatly benefit the detection and treatment of atherosclerotic disease. We describe such a delivery system based on a 9- amino acid cyclic peptide, LyP-1. LyP-1 was originally identified as a tumor-homing peptide... ver más... Application of fiber optic ATR-FTIR methods.. for therapeutic delivery systems Publicada el 04/18/2011. Autor: CL McFearin. Resumen: A fiber optic coupled ATR-FTIR spectroscopy technique was applied to the study of two different therapeutic delivery systems, acid degradable hydrogels and nanoparticles. Real time exponential release of a model protein, human serum albumin (HSA)... ver más... Preclinical screening of anti-HER2 nanobodies for molecular imaging of breast cancer Publicada el 04/18/2011. Autor: I Vaneycken. Resumen: Accurate determination of tumor human epidermal growth factor receptor 2 (HER2)- status in breast cancer patients is possible via noninvasive imaging, provided adequate tracers are used. In this study, we describe the generation of a panel of 38 nanobodies, small HER2-binding fragments that are derived from heavy-chain-only antibodies raised in an immunized dromedary. ver más... SiRNA delivery with exosome nanoparticles Publicada el 04/18/2011. Autor: JG van den Boorn. Resumen: A natural system for ferrying RNA between cells is used to transport siRNA to the mouse brain. ver más... Reactions inside nanoscale protein cages Abril 2011 Página 25
  • 30. Nanomedicina Publicada en RSC - Nanoscale latest articles, 04/03/2011. Autor: Saskia A. Resumen: Chemical reactions are traditionally carried out in bulk solution, but in nature confined spaces, like cell organelles, are used to obtain control in time and space of conversion. One way of studying these reactions in confinement is the development and use of small reaction vessels dispersed in solution, such as vesicles and micelles. ver más... NORMATIVAS CEN ISO/TS 13830:2011 Publicada en European Committee for Standardization (CEN) , 04/18/2011. Guidance on the labelling of manufactured nano-objects and products containing manufactured nano-objects ver más... Nanoscale carbon toxicity testing proposal submitted to EPA Publicada en ANSI - Nanotechnology Law Report, 04/07/2011. The NanoSafety Consortium for Carbon just submitted a proposed toxicity testing agreement to EPA under Section 4 of the Toxic Substances Control Act covering a range of nanoscale materials including multi-walled carbon nanotubes, double-walled carbon nanotubes, single-walled carbon nanotubes, and graphene. ver más... ASTM WK32796 - New Test Method Publicada en ASTM International's Committee E56 on Nanotechnology New Workitems, 04/07/2011. New test method for measurement of airborne metal and metal oxide nanoparticle surface area in inhalation exposure chambers using gas adsorption. ver más... Abril 2011 Página 26
  • 31. Nanomedicina INFORMES Y OTRAS Molecular Diagnostics in Cancer Testing Publicada en Biotechnology Market Research Reports, 04/30/2011. This TriMark Publications report describes the specific segment of the in vitro diagnostics (IVD) market known as molecular diagnostics (MD), with a specialization in the MD tests for cancer. In the current medical diagnostics market, molecular diagnostics for cancer testing offers one of the brightest areas for growth and innovation. ver más... Market Analyst Dissects Global Nano-medicine Market Publicada en European Platform of Nanomedicine Presentaciones, 04/28/2011. A recent RNCOS research report titled, Nanotechnology Market Forecast to 2013, states that the global nanomedicine market is estimated to grow at a CAGR of 13% in 2009 through 2013. ver más... Ethical and Societal Aspects of Nanotechnology Enabled ICT and Security Technologies Publicada en Nanoforum.org - Reports, 04/28/2011. In this report, public debates and literature on ethical and societal aspects of nanotechnology in ICT and security, and civil-military dual use aspects of nanotechnology are discussed. The main aim is to identify new or persistent issues in these debates that merit the attention of policy makers responsible for nanotechnology in Europe. ver más... Nanotechnology Research Directions for Societal Needs in 2020 Retrospective and Outlook Publicada en Australian Research Council Nanotechnology Network (ARCNN) Publications, 04/18/2011. The National Science Foundation(NSF) and the World Technology Evaluation Center(WTEC) have conducted a study on Nanotechnology Research directions titled "Nanotechnology Research Directions for Societal Needs in 2020 Retrospective and Outlook. ver más... Abril 2011 Página 27
  • 32. Nanomedicina Double-walled carbon nanotubes for medical imaging by MRI and other biomedical applications Publicada el 04/18/2011. Tesis doctoral. Carbon nanotubes (CNT) represent a great hope for different biomedical applications (drug delivery, controlled release, vaccines, medical imaging). The potential toxicity of CNT should however not be ignored and the Nanocomposites and Carbon Nanotubes (NCN) team at the CIRIMAT has participated as one of the leaders in this field (3 PhD students already, coordination of a national "ANR" programme, participation to the CARBIO Marie Curie RTN, etc.). ver más... Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives Publicada el 04/18/2011. In the past decade, nanomedicine with its promise of improved therapy and diagnostics has revolutionized conventional health care and medical technology. Dendrimers and dendrimer-based therapeutics are outstanding candidates in this exciting field as more and more biological systems have benefited from these starburst molecules. ver más... Abril 2011 Página 28