Depression is a mood disorder characterized by feelings of sadness, loss, or anger that interfere with daily activities. Around 8% of American adults experience depression. It can impact work productivity and relationships. There are several forms of depressive disorders including major depression, dysthymia, minor depression, psychotic depression, postpartum depression, and seasonal affective disorder. Risk factors include family history, childhood trauma, brain structure, medical conditions, and drug use. Treatments include antidepressants, antianxiety medications, and antipsychotic medications.