A presentation about heart break syndrome

1. Takotsubo cardiomyopathy
or heartbreak syndrome

2. Takotsubo
• “Takotsubo” is from the
Japanese name for an
octopus trap, which has a
shape that is similar to
the apical ballooning
configuration of the left
ventricle (LV) in systole
in the typical form of
this disorder.

3. Cardiomyopathy

4. Takotsubo Cardiomyopathy
• Takotsubo cardiomyopathy is a weakening of
the left ventricle, the heart's main pumping
chamber.
• Usually it’s the result of severe emotional or
physical stress.
– E.g. a sudden illness, the loss of a loved one, a
serious accident, or a natural disaster such as an
earthquake.

5. Historical Background

6. Symptoms
• Chest pain and shortness of breath
after severe stress (emotional or
physical)
• Electrocardiogram abnormalities that
mimic those of a heart attack
• No evidence of coronary artery
obstruction

7. Symptoms
• Movement abnormalities in the left
ventricle
• Ballooning of the left ventricle

8. Etipology
• The causes are not fully understood
yet. However, there are several
mechanisms were proposed.
• Multivessel coronary artery
spasm, impaired cardiac microvascular
function, impaired myocardial fatty
acid metabolism, acute coronary
syndrome with reperfusion injury, etc.

9. Epidemiology
• 1.7-2.2% of patients who had suspected acute
coronary syndrome were subsequently
diagnosed with takotsubo cardiomyopathy
• Races: 57.2% were Asian, 40% were
Caucasian, and 2.8% were other races.
• A mean patient age of 67 years
• Nearly 90% of reported cases involve
postmenopausal women.

10. Prognosis
• Nearly 95% of patients experiencing complete
recovery within 4-8 weeks.
• The recurrence rate varies but is estimated at
6%. Estimates of mortality rates have ranged
from 1-3.2%.
• Fatal complications such as left ventricular free
wall rupture.

11. Made by ThuGiang
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