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ZOONOTIC DISEASE UNIT IN
KENYA: BLUE PRINT FOR A
NATIONAL ONE HEALTH OFFICE
Dr Murithi R. Mbabu
Department of Veterinary Services
Ministry of Agriculture, Livestock and Fisheries
Presentation Outline
 Key steps in OH in Kenya
 Outline of milestones in OH
 Application: One Health in Action
Kenya: Key OH Steps
(2005-2012)
 Formation of National Influenza Task

force(NIT) - 2005
 NIT responded to RVF outbreak as Rift Valley

Fever Task force - 2006/7
 Formation of Zoonotic Technical Working

Group (ZTWG)- 2008
 Development of Kenya’s priority zoonotic

diseases list – 2011
Kenya: Key OH Steps
(2005-2012) …
 Revision of IDSR technical guidelines to

incorporate zoonotic diseases -2011
 Creation of One Health office: Zoonotic

Disease Unit (ZDU) - 2011
 Development of Strategic Plan for

Implementing One Health in Kenya (2012 2017) – 2012
 Revision of national policies to incorporate

One Health- ongoing
OH Milestones in Kenya
(2006-2012)
1. Formation of Zoonotic Technical
Working Group (ZTWG)
Formed in 2008
 Multi-sectoral, including MoH, MoLD, WHO,
FAO, AU-IBAR KEMRI, CDC, KWS among
others
 Meets quarterly
 Chaired alternately by Director of Veterinary
Services or Director of Public Health and
Sanitation

2. Creation of One Health
office: Zoonotic Disease Unit (ZDU)
MOU: Signed by MoPHS and MoLD in Aug 2011

Housing: Office constructed on government land and
officially opened by the Minister for MoLD and

Minister for MoPHS – Oct 2012
Staff: Two Epidemiologists deployed by government
Support staff: Admin Assistant and Data Manager
(supported by donor)
ZDU Formation
Zoonotic Disease Forum: Sept 22-24, 2010
Launch of the ZDU

Minister, MOLD and PS MoPHS
officially open ZDU office
ZDU Organogram
3. Development of Kenya Priority
Zoonotic Diseases List –2011*
1.

Viral Hemorrhagic Fevers
i.
ii.
iii.
iv.
v.
vi.

2.
3.
4.
5.
6.
7.
8.
9.
10.
11.

Crimean Congo Hemorrhagic
Fever
Dengue Fever
Rift Valley Fever
Yellow fever
Ebola
Marburg Virus Fever

Avian influenza & influenza A
H1N1
Brucellosis
Leishmaniasis
Leptospirosis
Anthrax
Rabies
Bovine TB
Plague
Tularemia (Rabbit Fever)
Protozoa Infections

i.
ii.

12.
13.

Salmonellosis
Helminths
i.
ii.
iii.
iv.
v.

14.

Cryptosporidiosis
Toxoplasmosis

Trichinosis
Cysticercosis
Hydatidosis
Sarcoptic mange
Diphyllobothrium

Fungal Diseases
i.
ii.
iii.
iv.

Dermatophilosis
Histoplasmosis
Cryptococcosis
Aspergillosis

15.

Schistosomiasis

16.

West Nile Virus
Trypanosomiasis

17.

*Not ranked
4. Kenya Revised IDSR
Technical Guidelines
Key changes
 Addition of zoonotic diseases in the priority
disease list
 Inclusion of Veterinary Officer in the District

and County Public Health Emergency
Management Committees (PHEMC)
5.1.2 IDENTIFY MEMBERS OF THE PHEMC
Organize the district PHEMC to include a mix of representatives from the public, non
governmental organizations (NGO) and private sectors.
The following should be members of the PHEMC teams at provincial and district levels
-

Core group
District level
District Medical Officer of Health
Disease surveillance officer
Health Records Information Officer
Public Health Officer
Public Health Nurse
Medical Laboratory technologist
Clinical Officer
Health Education officer
Wildlife experts
Veterinary Officer
Nutritionist

Provincial /county level
PDPHS/Provincial/county Medical Officer
Disease surveillance officer
Health Records Information Officer
Public Health Officer
Public health Nurse
Medical Laboratory technologist
Clinical Officer
Health Education Officer
Wildlife experts
Veterinary Officer
Nutritionist
Table 1: Kenya’s Priority Diseases, Conditions and Events for
Integrated Dis ease Surveillance and Response – 2011
Epidemic prone diseases

1. Acute haemorrhagic
fever syndrome*
2. Anthrax
3. Cholera
4. Diarrhea with blood
(Shigella )
5. Measles
6. Meningococcal
meningitis
7. Plague
8. SARI**
9. Typhoid fever
10. Yellow fever
11. Brucellosis
*Ebola, Marburg, Rift
Valley, Lassa, Crimean
Congo, West Nile Fever

Diseases targeted for
eradication or elimination
1.
2.
3.
4.
5.
1

Dracunculiasis
Leprosy
Leishmaniasis
Neonatal tetanus
1
Poliomyelitis

Disease specified by IHR
(2005) for immediate
notification

Other major diseases,
events or conditions of
public health importance
1. Acute Jaundice
2. Adverse events
following
immunization (AEFI)
3. Diabetes mellitus
4. Diarrhea with
dehydration less than
5 years of age
5. HIV/AIDS (new
cases)
6. Hypertension
7. Road traffic Injuries
8. Malaria
9. Malnutrition in
children under 5
years of age
10. Maternal deaths
11. Rabies (animal
bites)
12. Severe pneumonia
less than 5 years of
age
13. STIs
14. Trachoma
15. a. Tuberculosis
b. MDR/XDR -TB
16. Substance abuse
17. Cancers
18. Neonatal deaths
19. Schistosomiasis
5. Strategic Plan for Implementing
OH in Kenya (2012-17) :Highlights
Strategic Plan for Implementing
OH in Kenya (2012-17)
Objectives:
 Strengthen surveillance,

prevention and control of zoonoses
 Establish structures

and partnerships to promote OH
 Conduct and Promote Applied

Research
To download visit WWW.ZDUKenya.org
Goal 1:Strengthen surveillance,
prevention and control of zoonoses
• Conducted risk mapping for 4 priority

zoonotic diseases
• Outbreak response - jointly responding to

zoonotic disease outbreaks
•
•
•
•

Rabies
Trypanosomosis
Dengue
Salmonellosis
Goal 1: Strengthen Zoonoses
Surveillance, Prevention and Control
 Identified subject matter experts for priority

zoonotic diseases
 Developed national guidelines on Rabies



Elimination strategy, based on PCP approach
Rabies Management guidelines

 Developed Rift Valley Fever national

guidelines




Contingency plan for Rift Valley fever
Risk mapping for Rift Valley fever
Goal 2 : Establish structures
and partnerships to promote OH

 Decentralize OH to the county and district levels




Sensitize the county heads
Train focal persons at the county levels
Establish mini-ZDU in Laikipia or Isiolo

 Develop OH communication strategy
 Decentralize OH to the county and district levels
Goal 2: Establish structures and
partnerships to promote One Health





ZDU operational
Quarterly Zoonotic
Technical Working
Group (ZTWG)
meetings
Linkages with OHCEA,
FAO, AU-IBAR, OIE,
WHO
Goal 3:Conduct and Promote
Applied Research
 Promote applied research at the human-animal-

ecosystem interface
 Brucellosis sero-prevalence study in Kajiado &
Kiambu counties
 Transmission of influenza virus from animals (pig) to
humans among pig farmers
 Plan to hold conference for universities, research
institutions and individual scientists on zoonotic
diseases
 Provide training and mentoring to veterinary, medical
and public health trainees
Strategic Plan Outcomes
 Greater compliance with WHO/IHR and OIE

guidelines on public health threats
 Risk maps and identification of hotspots for

zoonotic diseases
 Development and implementation of disease

prevention and control strategies for
zoonoses
Strategic Plan Outcomes…
 Established plan and capacity for early

epidemic detection, diagnosis, and rapid
response
 Better understanding of socio-economic

impacts of zoonotic diseases and their
interventions to households and the
government
6. Revision of National Policies
to Incorporate OH
 The veterinary policy – on going
 The National Health policy framework, 2011

to 2030 – ongoing
 Memorandum of understanding between

MoALF and MoH – Aug 2011
One Health in Action
Outline
 HAT investigation
 Brucellosis sero-prevalence study
 Development of disease control strategies
HAT Investigation: Introduction
 In March 2012, two case reports of Human

African Trypanosomiasis (HAT) reported from
tourists who had visited a national reserve
 Travel advisory from CDC given based on the
reports
 Joint Outbreak Investigation in 3 teams





Human health
Animal health
Entomological team
Human Investigation
Active surveillance

Setting up
surveillance sites.
Animal Investigation
Entomological Investigation

Ngu trap
Biconical trap
Findings/Actions
 No human infective forms of T. brucei

detected in human, animals or tsetse flies
 Five Sentinel surveillance sites established
Brucellosis Sero-prevalence Study
 Objectives
1. Establish representative prevalence estimates in

humans and animals in high and low prevalence
areas
2. Identify risk factors associated with brucellosis in
humans and animals in Kenya
3. To assess livestock owners knowledge, attitude and
practices regarding brucellosis
Brucellosis Sero-prevalence Study
 Sites

Marsabit – High prevalence
• Kajiado- High prevalence
• Kiambu- Low prevalence
 Study population
• Humans – ages > 5years
• livestock ( cattle, sheep, goats and camels)
 Specimens
• Serum samples
•
Brucellosis Sero-prevalence Study
Proportion of households with at least 1 positive human case
32%

14%
6%

Kajiado

Kiambu

Combined
Brucellosis Sero-prevalence Study
Proportion of herds with at least one positive animal case
31%

12%

11%

11%

6%
2%
Overall

Cows

Kajiado

1%
Goats

Kiambu

3%
Sheep
Disease Control strategies
 RVF

 Rabies
 Brucellosis
 Anthrax
Rabies Control Strategy
 Multiple agencies/institutions involved –

including WSPA
 WSPA Commitment
 Facilitate a

best practice learning trip to Kwazul

Natal, SA;
 Support in completion of elimination strategy;
 Support in acquisition of Rabies diagnostic kits –
dRIT;
 Assist in rabies outbreak response
“Medicine is a social science, and
politics is nothing else but medicine on a
large scale”
Rudolf
Virchow

Thank you

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Zoonotic Disease Unit Of Kenya: Blueprint For A National One Health Office

  • 1. ZOONOTIC DISEASE UNIT IN KENYA: BLUE PRINT FOR A NATIONAL ONE HEALTH OFFICE Dr Murithi R. Mbabu Department of Veterinary Services Ministry of Agriculture, Livestock and Fisheries
  • 2. Presentation Outline  Key steps in OH in Kenya  Outline of milestones in OH  Application: One Health in Action
  • 3. Kenya: Key OH Steps (2005-2012)  Formation of National Influenza Task force(NIT) - 2005  NIT responded to RVF outbreak as Rift Valley Fever Task force - 2006/7  Formation of Zoonotic Technical Working Group (ZTWG)- 2008  Development of Kenya’s priority zoonotic diseases list – 2011
  • 4. Kenya: Key OH Steps (2005-2012) …  Revision of IDSR technical guidelines to incorporate zoonotic diseases -2011  Creation of One Health office: Zoonotic Disease Unit (ZDU) - 2011  Development of Strategic Plan for Implementing One Health in Kenya (2012 2017) – 2012  Revision of national policies to incorporate One Health- ongoing
  • 5. OH Milestones in Kenya (2006-2012)
  • 6. 1. Formation of Zoonotic Technical Working Group (ZTWG) Formed in 2008  Multi-sectoral, including MoH, MoLD, WHO, FAO, AU-IBAR KEMRI, CDC, KWS among others  Meets quarterly  Chaired alternately by Director of Veterinary Services or Director of Public Health and Sanitation 
  • 7. 2. Creation of One Health office: Zoonotic Disease Unit (ZDU) MOU: Signed by MoPHS and MoLD in Aug 2011 Housing: Office constructed on government land and officially opened by the Minister for MoLD and Minister for MoPHS – Oct 2012 Staff: Two Epidemiologists deployed by government Support staff: Admin Assistant and Data Manager (supported by donor)
  • 8. ZDU Formation Zoonotic Disease Forum: Sept 22-24, 2010
  • 9. Launch of the ZDU Minister, MOLD and PS MoPHS officially open ZDU office
  • 11. 3. Development of Kenya Priority Zoonotic Diseases List –2011* 1. Viral Hemorrhagic Fevers i. ii. iii. iv. v. vi. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. Crimean Congo Hemorrhagic Fever Dengue Fever Rift Valley Fever Yellow fever Ebola Marburg Virus Fever Avian influenza & influenza A H1N1 Brucellosis Leishmaniasis Leptospirosis Anthrax Rabies Bovine TB Plague Tularemia (Rabbit Fever) Protozoa Infections i. ii. 12. 13. Salmonellosis Helminths i. ii. iii. iv. v. 14. Cryptosporidiosis Toxoplasmosis Trichinosis Cysticercosis Hydatidosis Sarcoptic mange Diphyllobothrium Fungal Diseases i. ii. iii. iv. Dermatophilosis Histoplasmosis Cryptococcosis Aspergillosis 15. Schistosomiasis 16. West Nile Virus Trypanosomiasis 17. *Not ranked
  • 12. 4. Kenya Revised IDSR Technical Guidelines Key changes  Addition of zoonotic diseases in the priority disease list  Inclusion of Veterinary Officer in the District and County Public Health Emergency Management Committees (PHEMC)
  • 13. 5.1.2 IDENTIFY MEMBERS OF THE PHEMC Organize the district PHEMC to include a mix of representatives from the public, non governmental organizations (NGO) and private sectors. The following should be members of the PHEMC teams at provincial and district levels - Core group District level District Medical Officer of Health Disease surveillance officer Health Records Information Officer Public Health Officer Public Health Nurse Medical Laboratory technologist Clinical Officer Health Education officer Wildlife experts Veterinary Officer Nutritionist Provincial /county level PDPHS/Provincial/county Medical Officer Disease surveillance officer Health Records Information Officer Public Health Officer Public health Nurse Medical Laboratory technologist Clinical Officer Health Education Officer Wildlife experts Veterinary Officer Nutritionist
  • 14. Table 1: Kenya’s Priority Diseases, Conditions and Events for Integrated Dis ease Surveillance and Response – 2011 Epidemic prone diseases 1. Acute haemorrhagic fever syndrome* 2. Anthrax 3. Cholera 4. Diarrhea with blood (Shigella ) 5. Measles 6. Meningococcal meningitis 7. Plague 8. SARI** 9. Typhoid fever 10. Yellow fever 11. Brucellosis *Ebola, Marburg, Rift Valley, Lassa, Crimean Congo, West Nile Fever Diseases targeted for eradication or elimination 1. 2. 3. 4. 5. 1 Dracunculiasis Leprosy Leishmaniasis Neonatal tetanus 1 Poliomyelitis Disease specified by IHR (2005) for immediate notification Other major diseases, events or conditions of public health importance 1. Acute Jaundice 2. Adverse events following immunization (AEFI) 3. Diabetes mellitus 4. Diarrhea with dehydration less than 5 years of age 5. HIV/AIDS (new cases) 6. Hypertension 7. Road traffic Injuries 8. Malaria 9. Malnutrition in children under 5 years of age 10. Maternal deaths 11. Rabies (animal bites) 12. Severe pneumonia less than 5 years of age 13. STIs 14. Trachoma 15. a. Tuberculosis b. MDR/XDR -TB 16. Substance abuse 17. Cancers 18. Neonatal deaths 19. Schistosomiasis
  • 15. 5. Strategic Plan for Implementing OH in Kenya (2012-17) :Highlights
  • 16. Strategic Plan for Implementing OH in Kenya (2012-17) Objectives:  Strengthen surveillance, prevention and control of zoonoses  Establish structures and partnerships to promote OH  Conduct and Promote Applied Research To download visit WWW.ZDUKenya.org
  • 17. Goal 1:Strengthen surveillance, prevention and control of zoonoses • Conducted risk mapping for 4 priority zoonotic diseases • Outbreak response - jointly responding to zoonotic disease outbreaks • • • • Rabies Trypanosomosis Dengue Salmonellosis
  • 18. Goal 1: Strengthen Zoonoses Surveillance, Prevention and Control  Identified subject matter experts for priority zoonotic diseases  Developed national guidelines on Rabies   Elimination strategy, based on PCP approach Rabies Management guidelines  Developed Rift Valley Fever national guidelines   Contingency plan for Rift Valley fever Risk mapping for Rift Valley fever
  • 19. Goal 2 : Establish structures and partnerships to promote OH  Decentralize OH to the county and district levels    Sensitize the county heads Train focal persons at the county levels Establish mini-ZDU in Laikipia or Isiolo  Develop OH communication strategy  Decentralize OH to the county and district levels
  • 20. Goal 2: Establish structures and partnerships to promote One Health    ZDU operational Quarterly Zoonotic Technical Working Group (ZTWG) meetings Linkages with OHCEA, FAO, AU-IBAR, OIE, WHO
  • 21. Goal 3:Conduct and Promote Applied Research  Promote applied research at the human-animal- ecosystem interface  Brucellosis sero-prevalence study in Kajiado & Kiambu counties  Transmission of influenza virus from animals (pig) to humans among pig farmers  Plan to hold conference for universities, research institutions and individual scientists on zoonotic diseases  Provide training and mentoring to veterinary, medical and public health trainees
  • 22. Strategic Plan Outcomes  Greater compliance with WHO/IHR and OIE guidelines on public health threats  Risk maps and identification of hotspots for zoonotic diseases  Development and implementation of disease prevention and control strategies for zoonoses
  • 23. Strategic Plan Outcomes…  Established plan and capacity for early epidemic detection, diagnosis, and rapid response  Better understanding of socio-economic impacts of zoonotic diseases and their interventions to households and the government
  • 24. 6. Revision of National Policies to Incorporate OH  The veterinary policy – on going  The National Health policy framework, 2011 to 2030 – ongoing  Memorandum of understanding between MoALF and MoH – Aug 2011
  • 25. One Health in Action
  • 26. Outline  HAT investigation  Brucellosis sero-prevalence study  Development of disease control strategies
  • 27. HAT Investigation: Introduction  In March 2012, two case reports of Human African Trypanosomiasis (HAT) reported from tourists who had visited a national reserve  Travel advisory from CDC given based on the reports  Joint Outbreak Investigation in 3 teams    Human health Animal health Entomological team
  • 31. Findings/Actions  No human infective forms of T. brucei detected in human, animals or tsetse flies  Five Sentinel surveillance sites established
  • 32. Brucellosis Sero-prevalence Study  Objectives 1. Establish representative prevalence estimates in humans and animals in high and low prevalence areas 2. Identify risk factors associated with brucellosis in humans and animals in Kenya 3. To assess livestock owners knowledge, attitude and practices regarding brucellosis
  • 33. Brucellosis Sero-prevalence Study  Sites Marsabit – High prevalence • Kajiado- High prevalence • Kiambu- Low prevalence  Study population • Humans – ages > 5years • livestock ( cattle, sheep, goats and camels)  Specimens • Serum samples •
  • 34. Brucellosis Sero-prevalence Study Proportion of households with at least 1 positive human case 32% 14% 6% Kajiado Kiambu Combined
  • 35. Brucellosis Sero-prevalence Study Proportion of herds with at least one positive animal case 31% 12% 11% 11% 6% 2% Overall Cows Kajiado 1% Goats Kiambu 3% Sheep
  • 36. Disease Control strategies  RVF  Rabies  Brucellosis  Anthrax
  • 37. Rabies Control Strategy  Multiple agencies/institutions involved – including WSPA  WSPA Commitment  Facilitate a best practice learning trip to Kwazul Natal, SA;  Support in completion of elimination strategy;  Support in acquisition of Rabies diagnostic kits – dRIT;  Assist in rabies outbreak response
  • 38. “Medicine is a social science, and politics is nothing else but medicine on a large scale” Rudolf Virchow Thank you

Notas do Editor

  1. Conduct risk mapping for 4 priority zoonotic diseases (Anthrax, Rabies, Brucellosis, RVF) Implement OH plans for jointly responding to zoonotic disease outbreaksStrengthen laboratory diagnosis for zoonosisDevelop and implement prevention and control strategies for 4 priority zoonotic diseases