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Clinical Materials for
Self Learning - Medicine.

         Prepared by
  Dr. Ajith Karawita MBBS, MD
Objective
• To provide collection of clinical materials for
      your learning in Clinical Medicine.
   ( These materials are open for further discussion in
            addition to descriptions provided )

  Instructions
• Do not rush, carefully examine and analyse each point.
• Mail your suggestions – ajith.karawita@gmail.com
Acknowledgement
• I would like to express my sincere thanks to All patients.They
  have given their consent and fullest support for this exercise.
• I am grateful to my teacher , Dr Christie De Silva. MD, FRCP,
  Consultant physician & Nephrologist, NHSL, Colombo.
• My sincere thanks goes to Dr Wijelal Meegoda (MBBS, MD
  Radiology), Dr Ashanka Beligaswatta (MBBS, MD, MRCP) and
  Dr Darshani Wijewickrama (MBBS, MD) for reviewing this
  And to my colleagues who helped me immensely.
• Dr T. Thulasi (MBBS, MD)
• Dr Mathu Selvarajah (MBBS, MD)
• Dr Ajantha Rajapaksha (MBBS, MD)
• Dr Chamila Dabare (MBBS, MD)
Case No - 1

• A 65 yrs old female patient presented with
  left sided chest pain, cough and backache for
  about 2 months.
• PMH-Iron deficiency anaemia.
• Examine the CXR and describe radiological
  features. What is your diagnosis?
Don’t read description first:

Hypodense almost circular
lesion close to posterior
surface of the left lung with
rib erosion.
Case No - 2

• A 74 yrs old male patient presented with
  productive cough, shortness of breath.
• Describe the features in the CXR.
Don’t read
description first:

This patient has
undergone left
lobectomy about 40
yrs back due to
Bronchiectasis.this
time the featurs are
suggestive of
pulmonary TB with
bronchiectasis.
Don’t read description first: Note wiring of ribs – left lower two ribs.
Case No - 3
• A 33 yrs old male patient investigated for
  PUO.
• He had persistently high ESR over
  100mm/1st h.
• Renal and liver functions were normal.
• Describe the abnormalities you see in the
  CT-Brain.
Non-contrast CT-Brain
IV Contrast CT-Brain
A hypodense area seen in the region of posterior limb
of the left internal capsule.

Small hypodensity also seen in the region of right
internal capsule as evident in non contrast film.
No other enhancing lesions, no midline shift.
ventricular systems, basal cisterns are within normal
limits, no haemorrhages are seen.

CT appearance – left and right internal capsule
infarction.
Case No - 4

• A 37 yrs old male presented with fever with
  chills and rigors for 2 wks.
• There was firm splenomegaly.
• PMH – Typhoid 1yr back.
• Describe the CXR abnormalities.
• What is the differential diagnosis?
Don’t read description first: Cavitating lesion of active TB
Case No - 5
• A 50 yrs old male patient admitted with signs and
  symptoms of urinary tract infections (UTI) for 5
  days.
• PMH – patient with chronic renal failure due to
  bilateral obstructive uropathy identified about 13
  yrs back.
  7 months back he underwent left urethrolithotomy
  and right nephrostomy due to acute on chronic
  CRF.
• Describe the abnormalities.
Case No - 6

• A 44 yrs old male patient presented with
  increased frequency of fits and left
  hemiparesis for 1day.
• PMH – known patient with epilepsy not on
  regular treatment.
  he has history of frequent falls and injury to
  right side of the head.
Don’t read description first: Frontal infarction and a depressed fracture
Case No - 7

• A 38 yrs old male patient presented with
  severe occipital headache, neck pain and
  blurring of vision for about 1 wk duration.
• Clinically he had hepatosplenomegaly and
  retinal infarcts.
• Comment on the FBC report.
Don’t read description first: This is from a patient with polycythemia complicated
with superior sagital sinus thrombosis. He is on anticagulation therapy.
Case No - 8

• This patient was investigated for apperently
  elevated diaphragm in the CXR.
• She had persistently elevated ESR and CRP
  with marginal elevation of transaminases.
• Then CT-abdomen done.
• Examine and describe the abnormalities.
Case No - 9
• A 54 yrs old male patient admitted with
  shortness of breath, cough, and fever for 2
  wks.
• PMH – non insulin dependent diabetes
  mellitus for about 8 yrs, hepatitis B, left
  side bronchial carcenoma which was
  declared cleared 2 years back.
• Describe the CXR. What are the findings,
  how are you going to manage this patient?
Don’t read description first: Nodular shadows at right hilum, with effusion and
consolidation.
Case No - 10

• A 26 yrs old patient admitted with fever and
  myalgia for 3 days.
• His platelet count has dropped to 19,000
  cumm, PCV was at upper limit of normal,
  transaminases increased about three times.
• Look at the puncture site in the next slide a
  peculiar lesion. it recurred once it has been
  broken by patient.
Don’t read description first: Peculiar lesion at puncture site It is not just a bulb of
blood, macroscopically it has a membrane
Case No - 11

• A 74 yrs old male patient presented with
  productive cough and shortness of breath for 1
  month duration.
• He also had backache and high ESR for about 1
  month.
• Mantoux was 22mm,
• Describe the abnormalities in the lumbosacral
  spine of this patient and comment on the serum
  electrophoresis report.
• How are you going to investigate this patient.
Don’t read description first: There is slight increase of alpha-2 globulin, no
monoclonal band ?infection
Case No - 12
• A 75 yrs old male patient admitted with
  bilateral chest pain which is like lightening
  pain for about 1wk.
• PMH – TB was completely treated 10 yrs
  back.
• Describe the abnormalities in the CXR,
  what is your differential diagnosis and how
  are you going to investigate this patient ?
Don’t read description first:

Multiple hyperdense circualar
shadows at the apex of both
lungs.
Case No - 13

• A 22 yrs old patient admitted with diarrhoea
  for 2 wks and fever for 1day.
• Look at the CXR identify abnormalities.
  (history is not related to findings in the
  CXR).
Don’t read description
first:

Note that anterior ends of the
3rd and 4th ribs of right side
are more wider.
Case No - 14
• A 66 yrs old male patient came with
  polyuria, polydipsia for 1 yrs duration.
• On investigation – patient had diabetes
  mellitus and urinary tract infections.
• Describe the abnormalities in the X-ray
  KUB (kidney, bladder, ureter).
• How are you going to manage this patient?
Don’t read description first:

You can see bilateral Staghorn
calculi.
Case No - 15

• What is your spot diagnosis?
Don’t read description first: Scar of herpes zoster. In fact he had this active
lesion about 1yrs ago, which was not a complicated one, rash only lasted about 5
days.
Case No - 16

 How do you collect
 sputum for AFB?
Case No - 17

• A 60 yrs old female fat lady presented with chest
  pain for 1 day.
• PMH – hypertension for 5 yrs, ischemic heart
  disease for 1 ½ yrs.
• Patient didn’t tolerate exercise ECG.
• Next slide you will see a coronary calcium score
  of this patient.
• Interpret the results.
• What is the significance of coronary calcium
  score.
• How you perform coronary calcium score?
Coronary Calcium Score
Left Main Artery (LMA)                0
Left Anterior Descending (LAD)        0
Left Circumflex (LCX)                 0
Right Coronary Artery (RCA)         102
Posterior Descending Artery           0
(PDA)
TOTAL                               102

The diagram demonstrate the general location of
coronary artery calcification only. Does not necessarily
indicate the presence or location of a stenotic lesion.
Coronary calcium score is performed as same as CT scanning is performed,
but only chest is scanned and score is calculated by a different software.

Information is based on analysis of the coronary arteries. Calcium deposits
do not correspond directly to the percentage of narrowing of arteries only.

They do correlate directly to the amount of coronary plaque and to the risk of
future coronary disease. These calcium deposits usually begin to form years
before any symptoms develop. Early detection and modification of risk
factors such as smoking , high cholesterol can slow the progress of coronary
artery disease.

A low score suggest a low likelihood of coronary artery disease but does not
exclude the possibility of significant coronary artery narrowing. The results
should be discussed with your physician taking into account other risk factors
such as age, gender, family history, diabetes, smoking or high cholesterol
levels.
Case No - 18




Note any abnormality
Case No - 19

• A 26 yrs old male patient admitted with
  right hypochondrial pain for 1 wk.
• Describe the CXR.
• How would you investigate this patient.
Don’t read description first: There is a small pleural effusion in right side of the
lung, Can you assess the amount of fluid?
Case No - 20

• A 78 yrs old male patient presented with
  polyuria, polydipsia and body weakness.
• PMH –diabetes mellitus for 5 yrs. and
  pulmonary TB completely treated about 50
  yrs back.
• Describe the CXR abnormalities.
Case No - 21


• Identify the lesion
Case No - 22


• Describe the following two FBCs.
• How are you going to identify the patient’s
  condition.
• What further investigation do you need to
  confirm your diagnosis.
Case No - 23

• Comment on the following serum
  electrophoresis report.
Don’t read description first: Slight polyclonal increase of Gamma globulin, No
monoclonal bands ?infection
Case No - 24

• Identify the clinical sign
• What could be the causes for the appearance
• How would you grade that.
Finger clubbing could be due to

A. Congenital – no disease
B. Lung disease – bronchial carcenoma, chronic
   suppurative lung disease (bronchiectasis, lung abscess,
   empyma), pulmonary fibrosis, pleural and mediastinal
   tumours (mesothelioma), cryptogentic organizing
   pneumonia
C. Heart disease – cyanaotic heart disease, subacute
   infective endocarditis, atrial myxome,
D. Liver disease – Cirrhosis
E. Bowel disease – inflammatory bowel disease
Thanks

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Clinical materials for medicine VI

  • 1. Clinical Materials for Self Learning - Medicine. Prepared by Dr. Ajith Karawita MBBS, MD
  • 2. Objective • To provide collection of clinical materials for your learning in Clinical Medicine. ( These materials are open for further discussion in addition to descriptions provided ) Instructions • Do not rush, carefully examine and analyse each point. • Mail your suggestions – ajith.karawita@gmail.com
  • 3. Acknowledgement • I would like to express my sincere thanks to All patients.They have given their consent and fullest support for this exercise. • I am grateful to my teacher , Dr Christie De Silva. MD, FRCP, Consultant physician & Nephrologist, NHSL, Colombo. • My sincere thanks goes to Dr Wijelal Meegoda (MBBS, MD Radiology), Dr Ashanka Beligaswatta (MBBS, MD, MRCP) and Dr Darshani Wijewickrama (MBBS, MD) for reviewing this And to my colleagues who helped me immensely. • Dr T. Thulasi (MBBS, MD) • Dr Mathu Selvarajah (MBBS, MD) • Dr Ajantha Rajapaksha (MBBS, MD) • Dr Chamila Dabare (MBBS, MD)
  • 4. Case No - 1 • A 65 yrs old female patient presented with left sided chest pain, cough and backache for about 2 months. • PMH-Iron deficiency anaemia. • Examine the CXR and describe radiological features. What is your diagnosis?
  • 5. Don’t read description first: Hypodense almost circular lesion close to posterior surface of the left lung with rib erosion.
  • 6. Case No - 2 • A 74 yrs old male patient presented with productive cough, shortness of breath. • Describe the features in the CXR.
  • 7. Don’t read description first: This patient has undergone left lobectomy about 40 yrs back due to Bronchiectasis.this time the featurs are suggestive of pulmonary TB with bronchiectasis.
  • 8. Don’t read description first: Note wiring of ribs – left lower two ribs.
  • 9. Case No - 3 • A 33 yrs old male patient investigated for PUO. • He had persistently high ESR over 100mm/1st h. • Renal and liver functions were normal. • Describe the abnormalities you see in the CT-Brain.
  • 10.
  • 11.
  • 14. A hypodense area seen in the region of posterior limb of the left internal capsule. Small hypodensity also seen in the region of right internal capsule as evident in non contrast film. No other enhancing lesions, no midline shift. ventricular systems, basal cisterns are within normal limits, no haemorrhages are seen. CT appearance – left and right internal capsule infarction.
  • 15. Case No - 4 • A 37 yrs old male presented with fever with chills and rigors for 2 wks. • There was firm splenomegaly. • PMH – Typhoid 1yr back. • Describe the CXR abnormalities. • What is the differential diagnosis?
  • 16. Don’t read description first: Cavitating lesion of active TB
  • 17. Case No - 5 • A 50 yrs old male patient admitted with signs and symptoms of urinary tract infections (UTI) for 5 days. • PMH – patient with chronic renal failure due to bilateral obstructive uropathy identified about 13 yrs back. 7 months back he underwent left urethrolithotomy and right nephrostomy due to acute on chronic CRF. • Describe the abnormalities.
  • 18.
  • 19. Case No - 6 • A 44 yrs old male patient presented with increased frequency of fits and left hemiparesis for 1day. • PMH – known patient with epilepsy not on regular treatment. he has history of frequent falls and injury to right side of the head.
  • 20. Don’t read description first: Frontal infarction and a depressed fracture
  • 21. Case No - 7 • A 38 yrs old male patient presented with severe occipital headache, neck pain and blurring of vision for about 1 wk duration. • Clinically he had hepatosplenomegaly and retinal infarcts. • Comment on the FBC report.
  • 22. Don’t read description first: This is from a patient with polycythemia complicated with superior sagital sinus thrombosis. He is on anticagulation therapy.
  • 23. Case No - 8 • This patient was investigated for apperently elevated diaphragm in the CXR. • She had persistently elevated ESR and CRP with marginal elevation of transaminases. • Then CT-abdomen done. • Examine and describe the abnormalities.
  • 24.
  • 25. Case No - 9 • A 54 yrs old male patient admitted with shortness of breath, cough, and fever for 2 wks. • PMH – non insulin dependent diabetes mellitus for about 8 yrs, hepatitis B, left side bronchial carcenoma which was declared cleared 2 years back. • Describe the CXR. What are the findings, how are you going to manage this patient?
  • 26.
  • 27. Don’t read description first: Nodular shadows at right hilum, with effusion and consolidation.
  • 28. Case No - 10 • A 26 yrs old patient admitted with fever and myalgia for 3 days. • His platelet count has dropped to 19,000 cumm, PCV was at upper limit of normal, transaminases increased about three times. • Look at the puncture site in the next slide a peculiar lesion. it recurred once it has been broken by patient.
  • 29. Don’t read description first: Peculiar lesion at puncture site It is not just a bulb of blood, macroscopically it has a membrane
  • 30. Case No - 11 • A 74 yrs old male patient presented with productive cough and shortness of breath for 1 month duration. • He also had backache and high ESR for about 1 month. • Mantoux was 22mm, • Describe the abnormalities in the lumbosacral spine of this patient and comment on the serum electrophoresis report. • How are you going to investigate this patient.
  • 31.
  • 32. Don’t read description first: There is slight increase of alpha-2 globulin, no monoclonal band ?infection
  • 33. Case No - 12 • A 75 yrs old male patient admitted with bilateral chest pain which is like lightening pain for about 1wk. • PMH – TB was completely treated 10 yrs back. • Describe the abnormalities in the CXR, what is your differential diagnosis and how are you going to investigate this patient ?
  • 34.
  • 35. Don’t read description first: Multiple hyperdense circualar shadows at the apex of both lungs.
  • 36. Case No - 13 • A 22 yrs old patient admitted with diarrhoea for 2 wks and fever for 1day. • Look at the CXR identify abnormalities. (history is not related to findings in the CXR).
  • 37. Don’t read description first: Note that anterior ends of the 3rd and 4th ribs of right side are more wider.
  • 38.
  • 39. Case No - 14 • A 66 yrs old male patient came with polyuria, polydipsia for 1 yrs duration. • On investigation – patient had diabetes mellitus and urinary tract infections. • Describe the abnormalities in the X-ray KUB (kidney, bladder, ureter). • How are you going to manage this patient?
  • 40. Don’t read description first: You can see bilateral Staghorn calculi.
  • 41. Case No - 15 • What is your spot diagnosis?
  • 42. Don’t read description first: Scar of herpes zoster. In fact he had this active lesion about 1yrs ago, which was not a complicated one, rash only lasted about 5 days.
  • 43. Case No - 16 How do you collect sputum for AFB?
  • 44. Case No - 17 • A 60 yrs old female fat lady presented with chest pain for 1 day. • PMH – hypertension for 5 yrs, ischemic heart disease for 1 ½ yrs. • Patient didn’t tolerate exercise ECG. • Next slide you will see a coronary calcium score of this patient. • Interpret the results. • What is the significance of coronary calcium score. • How you perform coronary calcium score?
  • 45. Coronary Calcium Score Left Main Artery (LMA) 0 Left Anterior Descending (LAD) 0 Left Circumflex (LCX) 0 Right Coronary Artery (RCA) 102 Posterior Descending Artery 0 (PDA) TOTAL 102 The diagram demonstrate the general location of coronary artery calcification only. Does not necessarily indicate the presence or location of a stenotic lesion.
  • 46.
  • 47. Coronary calcium score is performed as same as CT scanning is performed, but only chest is scanned and score is calculated by a different software. Information is based on analysis of the coronary arteries. Calcium deposits do not correspond directly to the percentage of narrowing of arteries only. They do correlate directly to the amount of coronary plaque and to the risk of future coronary disease. These calcium deposits usually begin to form years before any symptoms develop. Early detection and modification of risk factors such as smoking , high cholesterol can slow the progress of coronary artery disease. A low score suggest a low likelihood of coronary artery disease but does not exclude the possibility of significant coronary artery narrowing. The results should be discussed with your physician taking into account other risk factors such as age, gender, family history, diabetes, smoking or high cholesterol levels.
  • 48. Case No - 18 Note any abnormality
  • 49.
  • 50. Case No - 19 • A 26 yrs old male patient admitted with right hypochondrial pain for 1 wk. • Describe the CXR. • How would you investigate this patient.
  • 51. Don’t read description first: There is a small pleural effusion in right side of the lung, Can you assess the amount of fluid?
  • 52. Case No - 20 • A 78 yrs old male patient presented with polyuria, polydipsia and body weakness. • PMH –diabetes mellitus for 5 yrs. and pulmonary TB completely treated about 50 yrs back. • Describe the CXR abnormalities.
  • 53.
  • 54. Case No - 21 • Identify the lesion
  • 55.
  • 56.
  • 57.
  • 58. Case No - 22 • Describe the following two FBCs. • How are you going to identify the patient’s condition. • What further investigation do you need to confirm your diagnosis.
  • 59.
  • 60.
  • 61. Case No - 23 • Comment on the following serum electrophoresis report.
  • 62. Don’t read description first: Slight polyclonal increase of Gamma globulin, No monoclonal bands ?infection
  • 63. Case No - 24 • Identify the clinical sign • What could be the causes for the appearance • How would you grade that.
  • 64.
  • 65. Finger clubbing could be due to A. Congenital – no disease B. Lung disease – bronchial carcenoma, chronic suppurative lung disease (bronchiectasis, lung abscess, empyma), pulmonary fibrosis, pleural and mediastinal tumours (mesothelioma), cryptogentic organizing pneumonia C. Heart disease – cyanaotic heart disease, subacute infective endocarditis, atrial myxome, D. Liver disease – Cirrhosis E. Bowel disease – inflammatory bowel disease