Development of Duodenum

1. Anatomy of
Duodenum
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7. Development of
Duodenum
(Page 79)
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8. Steps of Development
1- Formation of duodenal loop
which is convex forward.
2- Outgrowth of hepatic bud and
pancreatic buds.
3- Differential growth rate and
rotation.
4- Absorption of dorsal mesentery.

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11. Congenital Anomalies of
duodenum
1- Stenosis or atresia.
2- Persistence of parts of
mesoduodenum as duodenal
folds.
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13. Development of
Pancreas
(Page 81)
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14. Anatomy of
Pancreas
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16. Development of
Pancreas
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21. Development of Pancreas
• It is formed from 2 endodermal buds: ventral &
dorsal.
• Ventral pancreatic bud: It arises from the proximal
part of hepatic duct. It migrates together with
hepatic duct from ventral wall of foregut to its
dorsal wall to lie below dorsal bud. It forms lower
part of head of pancreas and uncinate process.
• Dorsal pancreatic bud: It arises from dorsal aspect
of foregut just cranial to hepatic bud. It grows
dorsally through mesoduodenum to form upper
part of head of pancreas, body and tail.
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22. Development of Pancreatic duct
• Anastomosis between 2 ducts of the
pancreatic buds.
• Definitive pancreatic duct is formed from:
–1- Duct of ventral bud which open in duodenum
with common bile duct.
–2- Anastomosis between 2 ducts.
–3- Distal part of duct of dorsal pancreatic bud.
–4- Proximal part of dorsal pancreatic duct may be
obliterated or remain as accessory pancreatic
duct. Dr. Sherif

23. Anomalies of Pancreas
• 1- Annular pancreas: A ring of pancreatic
tissue that surrounds the duodenum.
• 2- Persistence of accessory duct: due to
persistence of proximal part of dorsal
pancreatic bud.
• 3- Accessory pancreas: Pancreatic tissue in
abnormal site as in pyloric part of stomach or
duodenum.
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25. Development of
Liver & Gall
Bladder
(Page 83)
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29. NotochordSomites of Paraxial
mesoderm
Intermediate mesoderm
Intraembryonic
coelom
Pericardium
Pleura
Peritoneal
canal
Cardiogeni
c area
Septum
transversum
Dr. Sherif Fahmy

30. Ectoderm
Mesoderm
Endoderm
Buccopharyngeal membrane
Cloacal
membrane
Hindgut
Midgut
Foregut
Forebrain
Forebrain bulge
Pericardial bulge
Vitelline duct Allantois
Definitive yolk sac
Stomodeum
L.S. in folded embryo
Pericardiu
m
Septum
transversum
Heart
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31. Formation of MesentryFormation of Mesentry
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37. Pars Cystica
• It grows to give rise to:
– Gall bladder.
– Cystic duct.
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38. Anomalis
• 1- Double gall
bladder.
• 2- Bile duct atresia.
• 3- Absence of gall
bladder.
• 4- Accessory hepatic
duct.
Dr. Sherif Fahmy