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Dr. Kiran Pandey
MS General Surgery
Resident
Kathmandu Model Hospital
National Academy of Medical
Studies(NAMS)
Acute Abdomen
Moderator :
Dr. Bijendra
Dhoj Joshi
Head of Department,
Department of surgery
Kathmandu Model Hospital
Acute Abdomen
• Defined in the 27th edition of Stedman's Medical
Dictionary, acute abdomen is
"any serious acute intra-abdominal condition attended
by pain, tenderness, and muscular rigidity, and for
which emergency surgery must be considered.”
• Any cause for acute abdomen can occur coincident
with pregnancy.
Acute Abdomen
• Challenge to Surgeons
• Most common cause of surgical emergency
admission
• Encompass various conditions ranging from the
trivial to the life-threatening
• Clinical course can vary from minutes to hours, to
weeks
• May be acute exacerbation of a chronic problem
e.g. Chronic Pancreatitis, Vascular Insufficiency
Differential Diagnosis
The primary symptom of the "acute
abdomen" is
Abdominal pain
ASSESMENT
• A Full history
• Thorough physical examination
• Diagnosis made
An exact diagnosis often impossible to make after the
initial assessment, and often relying on further
investigation
Types of Abdominal Pain:
• Three types of pain exist:
1.Visceral
2.Parietal
3.Referred
Visceral Pain
• Due to stretching of fibers innervating the walls
of hollow or solid organs.
• It occurs early and poorly localized
• It can be due to early ischemia or
inflammation.
Parietal Pain
Caused by
 Irritation of parietal peritoneum fibers.
 occurs late and better localized.
 Can be localized to a dermatome superficial to site
of the painful stimulus.
Referred Pain
• Pain is felt at a site away from the pathological
organ.
• Pain is usually ipsilateral to the involved organ and
is felt midline if pathology is midline.
• Pattern based on developmental embryology.
Referred Pain Locations
Acute Abdominal Pain
• Two approaches of evaluation
1. Classification of abd pain into systems
2. Abdominal Topography (4 quadrants)
Classification on Abdominal Pain
• Three main categories of abdominal pain:
Intra Abdominal
 Gastrointestinal
Appendetcicitis, Diverticulitis, etc
 Genitourinary:
Renal Colic, etc
Classification on Abdominal Pain
 Gyaenecology :
Acute PID, Pregnancy, etc
 Vascular systems
AAA, Mesenteric Ischemia etc.
Classification on Abdominal Pain
Extra-abdominal (less common) involves:
Cardiopulmonary (AMI, etc)
Abdominal wall (Hernia, Zoster etc)
Toxic-metabolic (DKA, OD, lead, etc)
Classification on Abdominal Pain
Neurogenic pain (Zoster, etc)
Psychic (Anxiety, Depression, etc)
Nonspecific Abd pain
 not well explained or described.
Abdominal Topography
History (S)
• Details of Pain:
site, nature, severity, associations
• Nausea, vomiting
Bloody? (Coffee grounds emesis?)
History (S)
• Change in urinary habits?
Urine appearance?
• Change in bowel habits?
Melena (Dark, tarry stools?)
• Regular food/water intake?
History (S)
Females
–Last menstrual period?
–Abnormal bleeding?
In females, abdominal pain =
GYN problem until proven otherwise
Abdominal Pain
• Location,
• Quality
• Severity
• Onset
• Duration of pain
• Aggravating and alleviating factors
GI symptoms
Nausea, Vomiting , Diarrhea
Abdominal Pain
• GU symptoms
Dysuria, Frequency, Testicular pain
• Vascular symptoms
Atrial fibrillation , Acute Myocardial Infarction,
Abdominal Aortic Aneurysm
Can overlap i.e. Nausea seen in both GI / GU
pathologies.
Historical features of Abd Pain
PMH
Recent / current medications
Past hospitalizations
Past surgery
Chronic disease
Social history
Occupation / Toxic exposure (CO / lead)
Physical Exam
Palpate each quadrant
Work toward area of pain
Warm hands
Patient on back, knee bent
(if possible)
Note: tenderness, rigidity,
guarding, masses
Physical Examination of the Abdomen
• Note pt’s general appearance.
• Realize that the intensity of the abdominal pain
• May have no relationship to severity of illness.
• One of the initial steps of the PE should be obtaining
and interpreting the vitals.
• Pts with visceral pain are unable to lie still.
• Pts with peritonitis like to stay immobile.
Physical Examination of the Abdomen
• INSPECTION:
Distention, scars, masses, rash.
• AUSCULATION:
Hyperactive,
Obstructive, absent, or normal bowel
sounds.
Physical Examination of the Abdomen
PALPATION:
Guarding, rigidity,
Rebound tenderness,
Organomegaly, or hernias.
Women should have pelvic exam
check FHR if pregnant.
Anyone with a rectum should have rectal exam.
Laboratory Test
 CBC
 UA / Urine culture
 Lactic acid
 LFT / Amylase / Lipase
 CE / Troponin
 HCG (quant / qual)
 Stool Culture
Radiographic Test
• Plain abdominal radiographs or abdominal series
Several limitations
Subject to reader interpretation.
• CT scan in conjunction with ultrasound is
superior in identifying any abnormality seen on
plain film.
Specific Diagnoses
In patients above fifty years of age
• Biliary Tract Disease (21%,)
• NSAP (16%),
• Appendicitis(15%), and
• Bowel Obstruction (12%).
In patients under fifty years of age
• NSAP (40%,)
• Appendicitis (32%,)
• and Other (13%.)
Appendicitis
• Usually due to
obstruction with fecalith
• Appendix becomes swollen,
inflamed gangrene, possible
perforation

Appendicitis
• Pain begins periumbilical; moves to RLQ
• Nausea, vomiting, anorexia, fever
• Patient lies on side; right hip, knee flexed
• Pain may not localize to RLQ if appendix in odd
location
• Sudden relief of pain = possible perforation
Acute Appendicitis
• Clinical features with some predictive value include:
• Pain located in the RLQ
• Pain migration from the periumbilical area to the
RLQ
• Rigidity
• Pain before vomiting
• Positive psoas sign
• Note: Anorexia is not a useful symptom
(33% pts not anorectic preoperatively.)
Acute Appendicitis
• Ultrasound can be used for detection, but CT is
preferred in adults and non-pregnant women.
• The CT scan can be with and without contrast
(oral & IV.)
• A neg. CT does not exclude diagnosis, but a
positive scan confirms it.
Peptic Ulcer Disease
• Steady, well-localized epigastric or
LUQ pain
• Described as a “burning”, “gnawing”,
“aching”
• Increased by coffee, stress, spicy
food, smoking
• Decreased by alkaline
food, antacids
Peptic Ulcer Disease
• Erosion of the lining of the
stomach, duodenum, or esophagus
• May cause massive GI bleed
• Patient lies very still with complaint of
Intense, steady pain, rigid abdomen with exam
Suspect perforation
Gastroesophageal Reflux
• Also known as GERD
• Signs and symptoms can mimic
cardiac pain.
• Usually onset after eating.
• Typically resolved with medication.
Cholecystitis
• Inflammation of gall bladder
• Commonly associated with gall
stones
• More common in 30 to 50 year old
females
• Nausea, vomiting; RUQ pain,
tenderness; fever
• Attacks triggered by ingestion of
fatty foods
Biliary Tract Disease
• Most common diagnosis in pts > 50.
• Composed of:
• Acute Cholecystitis (acalculus / calculus)
• Biliary Colic
• Common Duct Obstruction (Ascending
Cholangitis – painful jundice / fever / MSΔ).
• Of those patients found to have acute
cholecystitis, the majority lack fever and 40% lack
leukocytosis.
Biliary Tract Disease
• Patients may complain of:
– Diffuse pain in upper half of abdomen
– Generalized tendernaess throughout
belly
– RUQ or RLQ pain.
Biliary Tract Disease
• Sonography (US) is the initial test of choice
• More sensitive than CT scan to detect CBD obstruction.
• CT scan is better in the identification of cholecystitis
than in the detection of CBD obstruction.
• Cholescintigraphy (radionclide / HIDA scan) of the
biliary tree is a more sensitive test than US for the
diagnosis of both of these conditions.
Biliary Tract Disease
MR cholangiography (MRCP)
– Has good specificity and sensitivity in picking up stones
and common duct obstructions.
– Less invasive / less complications than ERCP
– (ERCP can induce GI perforation, pancreatitis, biliary duct
injury)
Bowel Obstruction
• Blockage of inside of intestine
• Interrupts normal flow of contents
• Causes include adhesions, hernias, fecal
impactions, tumors
• Cramping abdominal pain, nausea, vomiting
(often of fecal matter), abdominal
distension
Small Bowel Obstruction
• SBO may result from previous abdominal surgeries.
• Patient may present with intermittent, colicky pain,
abdominal distention, and abnormal BS.
• Only 2 historical features
Previous abd surgery and Intermittent / colicky pain
• 2 physical findings
Abdominal distention
Abnormal BS
Appear to have predictive value in diagnosing SBO.
Small Bowel Obstruction
• Plain abd films
Has a large number of indeterminate readings
Very limited due to the following:
Pt is obese
Pt is bedridden / contracted
(limited lateral decub / upright view)
Technical limitations
ABDOMINAL XR
Bowel Obstruction
Small Bowel
Central
Valvulae conniventes
Dia > 5cm
Large Bowel
 Peripheral
 Haustrae
> 10cm
SBO LBO
Small Bowel Obstruction
• CT scan is better than plain film in detecting high
grade SBO.
• CT scan can also give more info that might not be
seen on plain film (i.e. ischemic bowel)
• Low grade SBO may require small bowel
follow through.
Pancreatitis
• Inflammation of pancreas
• Triggered by
Ingestion of EtOH;
large amounts of fatty foods
• Nausea, vomiting;
• Abdominal tenderness;
• Pain radiating from upper abdomen straight
through to back
• Signs, symptoms of hypovolemic shock
Acute Pancreatitis
• 80% of cases are due to ETOH abuse or gallstones.
• Other common causes:
– Drugs ( Valproic acid, Tetracycline,
Hydrochlorothiazide, Furosemide)
– Pancreatic cancer
– Abdominal trauma/surgery
– Ulcer with pancreatic involvement
– Familial pancreatitis
Hyper triglycerides / Hypercalcemia
– Iatrogenic (ERCP)
– Sting of the scorpion Tityus trinitatis
• Definition :
– Inflammation of the pancreas
– Associated with edema, pancreatic autodigestion,
necrosis and possible hemorrhage
Acute Pancreatitis
• Only a minority number of pts present with
Pain and tenderness limited to the anatomic area
(in the upper half of the abdomen.)
• 50% of pts present
Pain extending well beyond the upper
abd to cause generalized tenderness.
Acute Pancreatitis
• The inflammatory process around the
pancreas may cause other signs and
symptoms such as:
– Pleural effusion
– Grey Turner's sign ( flank discoloration )
– Cullen's sign ( discoloration around the umbilicus )
– Ascites
– Jaundice
Acute
Pancreatitis
• Lipase testing is preferred in ED.
• Other test to consider:
• (CBC, Amylase, lipase, UA)
• The height of the pancreatic enzyme
elevations do not have prognostic value
• A double contrast helical CT scan stages severity
and predicts mortality sooner than Ranson’s
Criteria.
Acute Pancreatitis
• Should consider ICU admission for pts with high
Ranson’s Criteria.
• When making the diagnosis of Acute
Pancreatitis, it maybe necessary to assess the
pt for the following:
1. Biliary pancreatitis
2. Peripancreatic complications
Acute Pancreatitis
Biliary pancreatitis
-Due to CBD obstruction.
-Can lead to Ascending Cholangitis
Clinical findings: fever, Jaundice / icterus
Lab findings: ↑AST /ALT,
↑Total Bilirubin
Acute Pancreatitis
• Radiological study:
MRCP - Test of choice to get clear images of the pancrease
and CBD.
Double contrast CT - can also be use, may have limited view
of the CBD – 2nd most common test to be ordered in ED
• Ultrasound – 1st most common test to be order in ED to
evaluate for CBD obstruction.
• More sensitive than CT scan to evaluate the CBD. Its use is
safer in pregnancy.
Acute Pancreatitis
Peripancreatic complications:
• Necrosis (Necrotizing Pancreatitis)
• Hemorrhage (Hemorrhagic Pancreatitis)
• Drainable fluid collections (Ruptured
Pancreatic Pseudocyst)
Clinical findings: May have a
• Distended Abd,
• Appear septic,
• Cullen’s sign, and / or Grey Turner’s Sign.
– Lab findings:
No definite lab test will help in the diagnosis.
May see decrease Hb or ↑Lactic Acid level.
– Radiological test: of
Evaluate for the above complications is a
double contrast CT scan.
Diverticulitis
• Pouches become
blocked and infected
with fecal matter
causing inflammation.
• Pain, perforation,
severe peritonitis.
Acute Diverticulitis
• Less than ¼ of pts present with LLQ pain.
• 1/3 of pts present with pain to the lower half of the
abdomen.
• 20% of elderly pts with operatively confirmed
diverticulitis lacked abdominal tenderness.
• Elderly pts are at risk for a severe and often fatal
complication of diverticulitis.
(Free perforation of the colon)
Acute Diverticulitis
• CT with contrast:
– Test of choice for Acute Diverticulitis.
– Can identify abscesses, other complications, and
inform surgical management strategies.
• US:
– Relies on identification of an inflamed
diverticulum to make the diagnosis which is often
obscured in pts with complicated diverticulitis.
Esophageal Varices
• Dilated veins in
lower part of
esophagus
• Common in EtOH
abusers, patients
with liver disease
• Produce massive
upper GI bleeds
Renal Colic
• Abrupt, colicky, unilateral flank pain
Radiates to the groin, testicle, or labia.
• Hematuria and plain abd films
• Noncontrast helical CT is standard for the diagnosis.
IVP has poor sensitivity and time consuming in ED
setting.
• Must rule out
AAA.
Kidney Stone
• Mineral deposits form in kidney,
move to ureter
• Often associated with history
of recent UTI
• Severe flank pain
radiates to groin, scrotum
• Nausea, vomiting,
hematuria
• Extreme restlessness
Acute Pelvic Inflammatory Disease
• Patient may complain of pain / tenderness in
lower abdomen, adnexal or cervix.
• Most importantly patient may complain of
abnormal vaginal discharge (most common
finding).
• Fever, palpable mass, ↑WBC have been
inconsistently associated with PID.
• The best noninvasive test is transvaginal
ultrasound.
Ectopic Pregnancy
• Fertilized egg is
implanted outside the
uterus.
• Growth causes
rupture and can lead
to massive bleeding.
• Patient c/o of severe
RLQ or LLQ pain with
radiation.
Ectopic Pregnancy
• Symptoms include abdominal pain (most
common) and vaginal bleeding (maybe the only
complaint).
• Female pts (child bearing age) that present with
these symptoms automatically get a pregnancy
test and HCG quantitative level.
Ectopic Pregnancy
• If the pt is pregnant,
Transvaginal US to evaluate for ectopic pregnancy.
• Clear view of an IUP in 2 perpendicular views
essentially excludes an ectopic pregnancy.
• If an IUP is not seen, this must be interpreted in
the context of the discriminatory zone (DZ) of the
quantitative HCG.
Ectopic Pregnancy
• The DZ (1500 mlU/ml) is the threshold level of serum
HCG, above which a normal IUP should be seen on
sonography.
• Failure of levels to increase HCG by about 66% within
48 h in 1st trim pregnancy : abnormal gestation
(either a threatened miscarriage or blighted
pregnancy from an ectopic.)
• If no diagnosis on US but high suspicion for ectopic
Laparoscopy is indicated.
Pelvic Inflammatory Disease
• Inflammation of the
fallopian tubes and
tissues of the pelvis
• Typically lower
abdominal or pelvic
pain, nausea, vomiting
Abdominal Aortic Aneurysm
• Localized weakness of
blood vessel wall with
dilation (like bubble on
tire)
• Pulsating mass in
abdomen
• Can cause lower back pain
• Ruptureshock,
exsanguination
Abdominal Aortic Aneurysm
• Dissections produce chest or upper back pain that
can migrates to abdomen as the dissection
extend distally.
• AAA rather than dissect, it enlarge, leak, and
rupture.
• <50% of pts with AAA present with hypotension,
abdominal/back pain, and/or pulsatile abd mass. Can
present similar to renal colic.
• Neither the presence or the absence of femoral pulse
or an abdominal bruit are helpful clinically.
Abdominal Aortic Aneurysm
• Palpation: enlarged aorta.
• Any stable pt > 50 yrs old
CT scan to exclude AAA from the differential
diagnosis.
• Can use bedside ultrasound FAST scan,
No information about leakage or rupture.
• MRI is limited in its ability to identify fresh
bleeding. It is not an appropriate emergency
procedure.
Mesenteric Ischemia (MI)
• Diagnosis can be divided into the following:
1. Arterial insufficiency
• Occlusive – Embolic (A. Fib) / Thrombotic
– Embolic MI has the most abrupt onset.
• Nonocclusive – Low flow state (AMI / Shock)
– Usually has clinical evidence of a low flow
state ( acute cardiac
disease)
Mesenteric Ischemia (MI)
2. Venous – Mesenteric Venous Thrombosis
• Occurs in hypercoagulable states.
• Usually is found in younger pts.
• Has a lower mortality.
• Can be treated with immediate
anticoagulation.
Mesenteric Ischemia
• Pt is usually older
• Significant co-morbidity, and with visceral type
abdominal pain poorly localized without tenderness.
• Pt may have a diversion for food or weight loss.
• Elevated Lactate level may help in the diagnosis.
Mesenteric Ischemia
• Abd films may have findings of perforated viscus and
/ or obstruction.
• May find pneumotosis intestinalis, free fluid,
dilated bowel consistent with an ileus and / or
obstructive pattern on CT scan.
• Angiography is the diagnostic and initial
therapeutic procedure of choice.
Ischemic Colitis
• It is a diagnosis of an older patient.
• Pain described as diffuse, lower abdominal pain in 80% of pts.
• Can be accompanied by diarrhea often mixed with blood in
60% of patients.
• Compares to mesenteric ischemia, this is not due to large vessel
occlusive disease.
• Angiography is not indicated. If it is performed it is often
normal.
Ischemic Colitis
• Can be seen post – Abd Aorta surgery
• The diagnosis is made by colonoscopy.
• A color doppler ultrasound can also be used.
• In most cases only segmental areas of the mucosa and
submucosa are affected.
• Chronic cases can lead to colonic stricture.
• Treatment may include conservative management or if bowel
necrosis occurs surgery may be needed for colectomy.
Extrabdominal Acute Cause
• Pain is usually in upper half of abdomen.
• A chest film should be done to look for pneumonia, pulmonary
infarction, pleura effusion, and / or pnemothorax.
• A neg. film plus pleuritic pain could mean PE.
• If epigastric pain is present one should inquire about cardiac
history, get and ECG, and consider further cardiac evaluation .
Cardiopulmonary
Extrabdominal Cause
• Carnett’s sign:
The examiner finds point of maximum abdominal
tenderness on patient. Patient asked to sit up half
way, and if palpation produces same or increased
tenderness than test is positive for an abdominal
wall syndrome.
• Abd wall syndrome overlaps with hernia,
neuropathic causes of acute abdominal pain
Abdominal Wall
Hernias
• Characterized by a defect through which
intraabdominal contents protrude during increases in
the intraabdominal pressure
• Several types exist: inguinal, incisional, periumbilical, and
femoral (common in Female).
• Uncomplicated hernias can be asymptomatic, aching /
uncomfortable, and reducible on exam.
• Significant pain could mean strangulation (blood supply is
compromised) / incarceration (not reducible).
Inguinal Hernia
• Protrusion of the
intestine through a
tear in the inguinal
canal.
• Usually identified by
abnormal mass in lower
quadrant, with or
without pain.
• Strangulation can lead to
necrosis.
Toxic causes for
Acute Abdominal Pain
• Pt may present with symptoms of N/V/D and/or +/- fever to
suggest a gastroenteritis or enterocolitis.
• Most of these infections are confine to the mucosa of the GI
tract, therefore, pts may not present with significant tenderness.
• Other Infectious etiology that can cause abd pain includes:
• GAS Pharyngitis, Henoch-Schonlein purpura, Rocky Mountain
spotted fever, Scarlet fever, early toxic shock syndrome.
Other Toxic causes for Acute
Abdominal Pain
• Other toxic cause includes poisoning and OD
– Black Widow Spider Abd muscle spasm
– Cocaine induced intestinal ischemia
– Iron poisoning
– Lead toxicity
– Mercury salts
– Electrical injury
– Opoid withdrawal
– Mushroom toxicity
– Isopropranol induced hemorrhagic gastritis
Metabolic causes for Acute
Abdominal Pain
• DKA
• AKA (ETOH)
– Note both AKA / DKA can be a cause or a
consequence of acute pancreatitis.
• Adrenal crisis
• Thyroid storm
• Hypo / hypercalcemia
• Sickle cell crisis
consider these causes for pain : splenomegaly /
heptomegaly, splenic infarct, cholecystitis,
pancreatitis, Salmonella infect, or mesenteric venous
thrombosis.
Neurogenic causes for Acute
Abdominal Pain
• “Hover Sign” – the pt show signs of discomfort
when the examining hand is hovering just above or
is passed very lightly over the area of dysesthesia.
• Zosteriform Radiculopathy- follows dermatome
distribution and is characterized by shooting or
continuous burning sensation.
• May be due to diabetic neuropathic
involvement of root, plexus, or nerve.
NSAP causes for Acute Abdominal Pain
• A good portion of ER patients will have
nonspecific abdominal pain.
• Patients may have nausea, midepigastric pain, or
RLQ tenderness.
• The lab workup is usually normal.
• WBC may be elevated.
• Diagnosis should be confirm with repeated
exam.
Special Considerations
• In pts >50 :mesenteric ischemia, ischemic colitis,AAA.
• In an elderly patient symptoms do not manifest in the same
manner as those younger.
• Compared to young pts, only 20% of elderly pts with abdominal
pain will be diagnose with NSAP
• Assume an elderly patient has a surgical cause of pain unless
proven otherwise.
• 40% of those > 65 yrs old that present to ED with abdominal
pain need surgery.
HIV/AIDS
• Enterocolitis with diarrhea and dehydration is most
common cause of abdominal pain.
• CMV related large bowel perforation is
possible.
• Watch for obstruction due to Kaposi Sarcoma,
lymphoma, or atypical mycobacteria.
• Watch for biliary tract disease (CMV,
Cryptosporidium.)
Treatment of Acute Abdominal Pain
• Hypotension:
– In younger pts probably due to volume depletion
from vomiting, diarrhea, decreased oral intake or
third spacing.
Treatment would be isotonic crystalloid.
– Younger patients may also have abdominal sepsis
(septic shock).
• Treatment would include isotonic crystalloid,
antibiotics, and vasopressors
Treatment of Acute Abdominal Pain
• Hypotension:
– In older patients CV disease should be added to
the differential.
• If AMI is the diagnosis, a aortic balloon pump
may be needed until angioplasty or bypass is
done. If CHF is diagnosed than dobutamine
with isotonic crystalloid may be used
– Must also consider hemorrhage as a cause:
• Initiate treatment with isotonic
crystalloid then consider blood
transfusion
Treatment of Acute Abdominal Pain
• Analgesics:
– Though in past ER physicians did not treat acute
abdominal pain with analgesics for fear of altering
or obscuring the diagnosis, current literature
favors the use of opoids judiciously in such
patients.
Treatment of Acute Abdominal Pain
• Antibiotics:
– Must be consider when treating
suspected abdominal sepsis or diffuse
peritonitis.
– Coverage should be aimed at anaerobes and
aerobic gram negatives.
– If SBP suspected, must cover for gram
positive aerobes.
– Examples of mononotherapy are cefoxitin,
cefotetan, ampicillin-sulbactam, or ticarcillin-
clavulanate.
Disposition of Acute Abdominal Pain
• Indications for admissions:
– Pts who appear ill.
– Very young / Elderly
– Immunocompromised
– Unclear diagnosis
– Intractable pain, nausea, or vomiting
– Altered mental status
– Those using drugs, alcohol, or that lack social
support.
– Pts with poor follow-up and/or noncompliant.
Disposition of Acute Abdominal Pain
• Non-specific abdominal pain
– If this is the working diagnosis, patients must be
re-examined in 24 hours. This may be done in the
outpatient setting.
References
1. SCHWARTZ'S PRINCIPLES OF SURGER 11th Edition
2. Bailey & Love's Short Practice of Surgery 26th edition
3. A manual of Clinical Surgery by S. Das : 8th Edition
4. https://emedicine.medscape.com/article/195976-
overview
5. https://radiopaedia.org
May Lord
Dhanwantari
bless us with
sound health and
protect from
COVID-19

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Acute abdomen

  • 1. Dr. Kiran Pandey MS General Surgery Resident Kathmandu Model Hospital National Academy of Medical Studies(NAMS) Acute Abdomen Moderator : Dr. Bijendra Dhoj Joshi Head of Department, Department of surgery Kathmandu Model Hospital
  • 2. Acute Abdomen • Defined in the 27th edition of Stedman's Medical Dictionary, acute abdomen is "any serious acute intra-abdominal condition attended by pain, tenderness, and muscular rigidity, and for which emergency surgery must be considered.” • Any cause for acute abdomen can occur coincident with pregnancy.
  • 3. Acute Abdomen • Challenge to Surgeons • Most common cause of surgical emergency admission • Encompass various conditions ranging from the trivial to the life-threatening • Clinical course can vary from minutes to hours, to weeks • May be acute exacerbation of a chronic problem e.g. Chronic Pancreatitis, Vascular Insufficiency
  • 5. The primary symptom of the "acute abdomen" is Abdominal pain
  • 6. ASSESMENT • A Full history • Thorough physical examination • Diagnosis made An exact diagnosis often impossible to make after the initial assessment, and often relying on further investigation
  • 7. Types of Abdominal Pain: • Three types of pain exist: 1.Visceral 2.Parietal 3.Referred
  • 8. Visceral Pain • Due to stretching of fibers innervating the walls of hollow or solid organs. • It occurs early and poorly localized • It can be due to early ischemia or inflammation.
  • 9. Parietal Pain Caused by  Irritation of parietal peritoneum fibers.  occurs late and better localized.  Can be localized to a dermatome superficial to site of the painful stimulus.
  • 10. Referred Pain • Pain is felt at a site away from the pathological organ. • Pain is usually ipsilateral to the involved organ and is felt midline if pathology is midline. • Pattern based on developmental embryology.
  • 11.
  • 13. Acute Abdominal Pain • Two approaches of evaluation 1. Classification of abd pain into systems 2. Abdominal Topography (4 quadrants)
  • 14. Classification on Abdominal Pain • Three main categories of abdominal pain: Intra Abdominal  Gastrointestinal Appendetcicitis, Diverticulitis, etc  Genitourinary: Renal Colic, etc
  • 15. Classification on Abdominal Pain  Gyaenecology : Acute PID, Pregnancy, etc  Vascular systems AAA, Mesenteric Ischemia etc.
  • 16. Classification on Abdominal Pain Extra-abdominal (less common) involves: Cardiopulmonary (AMI, etc) Abdominal wall (Hernia, Zoster etc) Toxic-metabolic (DKA, OD, lead, etc)
  • 17. Classification on Abdominal Pain Neurogenic pain (Zoster, etc) Psychic (Anxiety, Depression, etc) Nonspecific Abd pain  not well explained or described.
  • 19. History (S) • Details of Pain: site, nature, severity, associations • Nausea, vomiting Bloody? (Coffee grounds emesis?)
  • 20. History (S) • Change in urinary habits? Urine appearance? • Change in bowel habits? Melena (Dark, tarry stools?) • Regular food/water intake?
  • 21. History (S) Females –Last menstrual period? –Abnormal bleeding? In females, abdominal pain = GYN problem until proven otherwise
  • 22. Abdominal Pain • Location, • Quality • Severity • Onset • Duration of pain • Aggravating and alleviating factors GI symptoms Nausea, Vomiting , Diarrhea
  • 23. Abdominal Pain • GU symptoms Dysuria, Frequency, Testicular pain • Vascular symptoms Atrial fibrillation , Acute Myocardial Infarction, Abdominal Aortic Aneurysm Can overlap i.e. Nausea seen in both GI / GU pathologies.
  • 24. Historical features of Abd Pain PMH Recent / current medications Past hospitalizations Past surgery Chronic disease Social history Occupation / Toxic exposure (CO / lead)
  • 25. Physical Exam Palpate each quadrant Work toward area of pain Warm hands Patient on back, knee bent (if possible) Note: tenderness, rigidity, guarding, masses
  • 26. Physical Examination of the Abdomen • Note pt’s general appearance. • Realize that the intensity of the abdominal pain • May have no relationship to severity of illness. • One of the initial steps of the PE should be obtaining and interpreting the vitals. • Pts with visceral pain are unable to lie still. • Pts with peritonitis like to stay immobile.
  • 27. Physical Examination of the Abdomen • INSPECTION: Distention, scars, masses, rash. • AUSCULATION: Hyperactive, Obstructive, absent, or normal bowel sounds.
  • 28. Physical Examination of the Abdomen PALPATION: Guarding, rigidity, Rebound tenderness, Organomegaly, or hernias. Women should have pelvic exam check FHR if pregnant. Anyone with a rectum should have rectal exam.
  • 29. Laboratory Test  CBC  UA / Urine culture  Lactic acid  LFT / Amylase / Lipase  CE / Troponin  HCG (quant / qual)  Stool Culture
  • 30. Radiographic Test • Plain abdominal radiographs or abdominal series Several limitations Subject to reader interpretation. • CT scan in conjunction with ultrasound is superior in identifying any abnormality seen on plain film.
  • 31. Specific Diagnoses In patients above fifty years of age • Biliary Tract Disease (21%,) • NSAP (16%), • Appendicitis(15%), and • Bowel Obstruction (12%). In patients under fifty years of age • NSAP (40%,) • Appendicitis (32%,) • and Other (13%.)
  • 32. Appendicitis • Usually due to obstruction with fecalith • Appendix becomes swollen, inflamed gangrene, possible perforation 
  • 33. Appendicitis • Pain begins periumbilical; moves to RLQ • Nausea, vomiting, anorexia, fever • Patient lies on side; right hip, knee flexed • Pain may not localize to RLQ if appendix in odd location • Sudden relief of pain = possible perforation
  • 34. Acute Appendicitis • Clinical features with some predictive value include: • Pain located in the RLQ • Pain migration from the periumbilical area to the RLQ • Rigidity • Pain before vomiting • Positive psoas sign • Note: Anorexia is not a useful symptom (33% pts not anorectic preoperatively.)
  • 35. Acute Appendicitis • Ultrasound can be used for detection, but CT is preferred in adults and non-pregnant women. • The CT scan can be with and without contrast (oral & IV.) • A neg. CT does not exclude diagnosis, but a positive scan confirms it.
  • 36. Peptic Ulcer Disease • Steady, well-localized epigastric or LUQ pain • Described as a “burning”, “gnawing”, “aching” • Increased by coffee, stress, spicy food, smoking • Decreased by alkaline food, antacids
  • 37. Peptic Ulcer Disease • Erosion of the lining of the stomach, duodenum, or esophagus • May cause massive GI bleed • Patient lies very still with complaint of Intense, steady pain, rigid abdomen with exam Suspect perforation
  • 38. Gastroesophageal Reflux • Also known as GERD • Signs and symptoms can mimic cardiac pain. • Usually onset after eating. • Typically resolved with medication.
  • 39. Cholecystitis • Inflammation of gall bladder • Commonly associated with gall stones • More common in 30 to 50 year old females • Nausea, vomiting; RUQ pain, tenderness; fever • Attacks triggered by ingestion of fatty foods
  • 40. Biliary Tract Disease • Most common diagnosis in pts > 50. • Composed of: • Acute Cholecystitis (acalculus / calculus) • Biliary Colic • Common Duct Obstruction (Ascending Cholangitis – painful jundice / fever / MSΔ). • Of those patients found to have acute cholecystitis, the majority lack fever and 40% lack leukocytosis.
  • 41. Biliary Tract Disease • Patients may complain of: – Diffuse pain in upper half of abdomen – Generalized tendernaess throughout belly – RUQ or RLQ pain.
  • 42. Biliary Tract Disease • Sonography (US) is the initial test of choice • More sensitive than CT scan to detect CBD obstruction. • CT scan is better in the identification of cholecystitis than in the detection of CBD obstruction. • Cholescintigraphy (radionclide / HIDA scan) of the biliary tree is a more sensitive test than US for the diagnosis of both of these conditions.
  • 43. Biliary Tract Disease MR cholangiography (MRCP) – Has good specificity and sensitivity in picking up stones and common duct obstructions. – Less invasive / less complications than ERCP – (ERCP can induce GI perforation, pancreatitis, biliary duct injury)
  • 44. Bowel Obstruction • Blockage of inside of intestine • Interrupts normal flow of contents • Causes include adhesions, hernias, fecal impactions, tumors • Cramping abdominal pain, nausea, vomiting (often of fecal matter), abdominal distension
  • 45. Small Bowel Obstruction • SBO may result from previous abdominal surgeries. • Patient may present with intermittent, colicky pain, abdominal distention, and abnormal BS. • Only 2 historical features Previous abd surgery and Intermittent / colicky pain • 2 physical findings Abdominal distention Abnormal BS Appear to have predictive value in diagnosing SBO.
  • 46. Small Bowel Obstruction • Plain abd films Has a large number of indeterminate readings Very limited due to the following: Pt is obese Pt is bedridden / contracted (limited lateral decub / upright view) Technical limitations
  • 48. Bowel Obstruction Small Bowel Central Valvulae conniventes Dia > 5cm Large Bowel  Peripheral  Haustrae > 10cm
  • 50. Small Bowel Obstruction • CT scan is better than plain film in detecting high grade SBO. • CT scan can also give more info that might not be seen on plain film (i.e. ischemic bowel) • Low grade SBO may require small bowel follow through.
  • 51. Pancreatitis • Inflammation of pancreas • Triggered by Ingestion of EtOH; large amounts of fatty foods • Nausea, vomiting; • Abdominal tenderness; • Pain radiating from upper abdomen straight through to back • Signs, symptoms of hypovolemic shock
  • 52. Acute Pancreatitis • 80% of cases are due to ETOH abuse or gallstones. • Other common causes: – Drugs ( Valproic acid, Tetracycline, Hydrochlorothiazide, Furosemide) – Pancreatic cancer – Abdominal trauma/surgery – Ulcer with pancreatic involvement
  • 53. – Familial pancreatitis Hyper triglycerides / Hypercalcemia – Iatrogenic (ERCP) – Sting of the scorpion Tityus trinitatis • Definition : – Inflammation of the pancreas – Associated with edema, pancreatic autodigestion, necrosis and possible hemorrhage
  • 54. Acute Pancreatitis • Only a minority number of pts present with Pain and tenderness limited to the anatomic area (in the upper half of the abdomen.) • 50% of pts present Pain extending well beyond the upper abd to cause generalized tenderness.
  • 55. Acute Pancreatitis • The inflammatory process around the pancreas may cause other signs and symptoms such as: – Pleural effusion – Grey Turner's sign ( flank discoloration ) – Cullen's sign ( discoloration around the umbilicus ) – Ascites – Jaundice
  • 56. Acute Pancreatitis • Lipase testing is preferred in ED. • Other test to consider: • (CBC, Amylase, lipase, UA) • The height of the pancreatic enzyme elevations do not have prognostic value • A double contrast helical CT scan stages severity and predicts mortality sooner than Ranson’s Criteria.
  • 57. Acute Pancreatitis • Should consider ICU admission for pts with high Ranson’s Criteria. • When making the diagnosis of Acute Pancreatitis, it maybe necessary to assess the pt for the following: 1. Biliary pancreatitis 2. Peripancreatic complications
  • 58. Acute Pancreatitis Biliary pancreatitis -Due to CBD obstruction. -Can lead to Ascending Cholangitis Clinical findings: fever, Jaundice / icterus Lab findings: ↑AST /ALT, ↑Total Bilirubin
  • 59. Acute Pancreatitis • Radiological study: MRCP - Test of choice to get clear images of the pancrease and CBD. Double contrast CT - can also be use, may have limited view of the CBD – 2nd most common test to be ordered in ED • Ultrasound – 1st most common test to be order in ED to evaluate for CBD obstruction. • More sensitive than CT scan to evaluate the CBD. Its use is safer in pregnancy.
  • 60. Acute Pancreatitis Peripancreatic complications: • Necrosis (Necrotizing Pancreatitis) • Hemorrhage (Hemorrhagic Pancreatitis) • Drainable fluid collections (Ruptured Pancreatic Pseudocyst) Clinical findings: May have a • Distended Abd, • Appear septic, • Cullen’s sign, and / or Grey Turner’s Sign.
  • 61. – Lab findings: No definite lab test will help in the diagnosis. May see decrease Hb or ↑Lactic Acid level. – Radiological test: of Evaluate for the above complications is a double contrast CT scan.
  • 62. Diverticulitis • Pouches become blocked and infected with fecal matter causing inflammation. • Pain, perforation, severe peritonitis.
  • 63. Acute Diverticulitis • Less than ¼ of pts present with LLQ pain. • 1/3 of pts present with pain to the lower half of the abdomen. • 20% of elderly pts with operatively confirmed diverticulitis lacked abdominal tenderness. • Elderly pts are at risk for a severe and often fatal complication of diverticulitis. (Free perforation of the colon)
  • 64. Acute Diverticulitis • CT with contrast: – Test of choice for Acute Diverticulitis. – Can identify abscesses, other complications, and inform surgical management strategies. • US: – Relies on identification of an inflamed diverticulum to make the diagnosis which is often obscured in pts with complicated diverticulitis.
  • 65. Esophageal Varices • Dilated veins in lower part of esophagus • Common in EtOH abusers, patients with liver disease • Produce massive upper GI bleeds
  • 66. Renal Colic • Abrupt, colicky, unilateral flank pain Radiates to the groin, testicle, or labia. • Hematuria and plain abd films • Noncontrast helical CT is standard for the diagnosis. IVP has poor sensitivity and time consuming in ED setting. • Must rule out AAA.
  • 67. Kidney Stone • Mineral deposits form in kidney, move to ureter • Often associated with history of recent UTI • Severe flank pain radiates to groin, scrotum • Nausea, vomiting, hematuria • Extreme restlessness
  • 68. Acute Pelvic Inflammatory Disease • Patient may complain of pain / tenderness in lower abdomen, adnexal or cervix. • Most importantly patient may complain of abnormal vaginal discharge (most common finding). • Fever, palpable mass, ↑WBC have been inconsistently associated with PID. • The best noninvasive test is transvaginal ultrasound.
  • 69. Ectopic Pregnancy • Fertilized egg is implanted outside the uterus. • Growth causes rupture and can lead to massive bleeding. • Patient c/o of severe RLQ or LLQ pain with radiation.
  • 70. Ectopic Pregnancy • Symptoms include abdominal pain (most common) and vaginal bleeding (maybe the only complaint). • Female pts (child bearing age) that present with these symptoms automatically get a pregnancy test and HCG quantitative level.
  • 71. Ectopic Pregnancy • If the pt is pregnant, Transvaginal US to evaluate for ectopic pregnancy. • Clear view of an IUP in 2 perpendicular views essentially excludes an ectopic pregnancy. • If an IUP is not seen, this must be interpreted in the context of the discriminatory zone (DZ) of the quantitative HCG.
  • 72. Ectopic Pregnancy • The DZ (1500 mlU/ml) is the threshold level of serum HCG, above which a normal IUP should be seen on sonography. • Failure of levels to increase HCG by about 66% within 48 h in 1st trim pregnancy : abnormal gestation (either a threatened miscarriage or blighted pregnancy from an ectopic.) • If no diagnosis on US but high suspicion for ectopic Laparoscopy is indicated.
  • 73. Pelvic Inflammatory Disease • Inflammation of the fallopian tubes and tissues of the pelvis • Typically lower abdominal or pelvic pain, nausea, vomiting
  • 74. Abdominal Aortic Aneurysm • Localized weakness of blood vessel wall with dilation (like bubble on tire) • Pulsating mass in abdomen • Can cause lower back pain • Ruptureshock, exsanguination
  • 75. Abdominal Aortic Aneurysm • Dissections produce chest or upper back pain that can migrates to abdomen as the dissection extend distally. • AAA rather than dissect, it enlarge, leak, and rupture. • <50% of pts with AAA present with hypotension, abdominal/back pain, and/or pulsatile abd mass. Can present similar to renal colic. • Neither the presence or the absence of femoral pulse or an abdominal bruit are helpful clinically.
  • 76. Abdominal Aortic Aneurysm • Palpation: enlarged aorta. • Any stable pt > 50 yrs old CT scan to exclude AAA from the differential diagnosis. • Can use bedside ultrasound FAST scan, No information about leakage or rupture. • MRI is limited in its ability to identify fresh bleeding. It is not an appropriate emergency procedure.
  • 77. Mesenteric Ischemia (MI) • Diagnosis can be divided into the following: 1. Arterial insufficiency • Occlusive – Embolic (A. Fib) / Thrombotic – Embolic MI has the most abrupt onset. • Nonocclusive – Low flow state (AMI / Shock) – Usually has clinical evidence of a low flow state ( acute cardiac disease)
  • 78. Mesenteric Ischemia (MI) 2. Venous – Mesenteric Venous Thrombosis • Occurs in hypercoagulable states. • Usually is found in younger pts. • Has a lower mortality. • Can be treated with immediate anticoagulation.
  • 79. Mesenteric Ischemia • Pt is usually older • Significant co-morbidity, and with visceral type abdominal pain poorly localized without tenderness. • Pt may have a diversion for food or weight loss. • Elevated Lactate level may help in the diagnosis.
  • 80. Mesenteric Ischemia • Abd films may have findings of perforated viscus and / or obstruction. • May find pneumotosis intestinalis, free fluid, dilated bowel consistent with an ileus and / or obstructive pattern on CT scan. • Angiography is the diagnostic and initial therapeutic procedure of choice.
  • 81. Ischemic Colitis • It is a diagnosis of an older patient. • Pain described as diffuse, lower abdominal pain in 80% of pts. • Can be accompanied by diarrhea often mixed with blood in 60% of patients. • Compares to mesenteric ischemia, this is not due to large vessel occlusive disease. • Angiography is not indicated. If it is performed it is often normal.
  • 82. Ischemic Colitis • Can be seen post – Abd Aorta surgery • The diagnosis is made by colonoscopy. • A color doppler ultrasound can also be used. • In most cases only segmental areas of the mucosa and submucosa are affected. • Chronic cases can lead to colonic stricture. • Treatment may include conservative management or if bowel necrosis occurs surgery may be needed for colectomy.
  • 83. Extrabdominal Acute Cause • Pain is usually in upper half of abdomen. • A chest film should be done to look for pneumonia, pulmonary infarction, pleura effusion, and / or pnemothorax. • A neg. film plus pleuritic pain could mean PE. • If epigastric pain is present one should inquire about cardiac history, get and ECG, and consider further cardiac evaluation . Cardiopulmonary
  • 84. Extrabdominal Cause • Carnett’s sign: The examiner finds point of maximum abdominal tenderness on patient. Patient asked to sit up half way, and if palpation produces same or increased tenderness than test is positive for an abdominal wall syndrome. • Abd wall syndrome overlaps with hernia, neuropathic causes of acute abdominal pain Abdominal Wall
  • 85. Hernias • Characterized by a defect through which intraabdominal contents protrude during increases in the intraabdominal pressure • Several types exist: inguinal, incisional, periumbilical, and femoral (common in Female). • Uncomplicated hernias can be asymptomatic, aching / uncomfortable, and reducible on exam. • Significant pain could mean strangulation (blood supply is compromised) / incarceration (not reducible).
  • 86. Inguinal Hernia • Protrusion of the intestine through a tear in the inguinal canal. • Usually identified by abnormal mass in lower quadrant, with or without pain. • Strangulation can lead to necrosis.
  • 87. Toxic causes for Acute Abdominal Pain • Pt may present with symptoms of N/V/D and/or +/- fever to suggest a gastroenteritis or enterocolitis. • Most of these infections are confine to the mucosa of the GI tract, therefore, pts may not present with significant tenderness. • Other Infectious etiology that can cause abd pain includes: • GAS Pharyngitis, Henoch-Schonlein purpura, Rocky Mountain spotted fever, Scarlet fever, early toxic shock syndrome.
  • 88. Other Toxic causes for Acute Abdominal Pain • Other toxic cause includes poisoning and OD – Black Widow Spider Abd muscle spasm – Cocaine induced intestinal ischemia – Iron poisoning – Lead toxicity – Mercury salts – Electrical injury – Opoid withdrawal – Mushroom toxicity – Isopropranol induced hemorrhagic gastritis
  • 89. Metabolic causes for Acute Abdominal Pain • DKA • AKA (ETOH) – Note both AKA / DKA can be a cause or a consequence of acute pancreatitis. • Adrenal crisis • Thyroid storm • Hypo / hypercalcemia • Sickle cell crisis consider these causes for pain : splenomegaly / heptomegaly, splenic infarct, cholecystitis, pancreatitis, Salmonella infect, or mesenteric venous thrombosis.
  • 90. Neurogenic causes for Acute Abdominal Pain • “Hover Sign” – the pt show signs of discomfort when the examining hand is hovering just above or is passed very lightly over the area of dysesthesia. • Zosteriform Radiculopathy- follows dermatome distribution and is characterized by shooting or continuous burning sensation. • May be due to diabetic neuropathic involvement of root, plexus, or nerve.
  • 91. NSAP causes for Acute Abdominal Pain • A good portion of ER patients will have nonspecific abdominal pain. • Patients may have nausea, midepigastric pain, or RLQ tenderness. • The lab workup is usually normal. • WBC may be elevated. • Diagnosis should be confirm with repeated exam.
  • 92. Special Considerations • In pts >50 :mesenteric ischemia, ischemic colitis,AAA. • In an elderly patient symptoms do not manifest in the same manner as those younger. • Compared to young pts, only 20% of elderly pts with abdominal pain will be diagnose with NSAP • Assume an elderly patient has a surgical cause of pain unless proven otherwise. • 40% of those > 65 yrs old that present to ED with abdominal pain need surgery.
  • 93. HIV/AIDS • Enterocolitis with diarrhea and dehydration is most common cause of abdominal pain. • CMV related large bowel perforation is possible. • Watch for obstruction due to Kaposi Sarcoma, lymphoma, or atypical mycobacteria. • Watch for biliary tract disease (CMV, Cryptosporidium.)
  • 94. Treatment of Acute Abdominal Pain • Hypotension: – In younger pts probably due to volume depletion from vomiting, diarrhea, decreased oral intake or third spacing. Treatment would be isotonic crystalloid. – Younger patients may also have abdominal sepsis (septic shock). • Treatment would include isotonic crystalloid, antibiotics, and vasopressors
  • 95. Treatment of Acute Abdominal Pain • Hypotension: – In older patients CV disease should be added to the differential. • If AMI is the diagnosis, a aortic balloon pump may be needed until angioplasty or bypass is done. If CHF is diagnosed than dobutamine with isotonic crystalloid may be used – Must also consider hemorrhage as a cause: • Initiate treatment with isotonic crystalloid then consider blood transfusion
  • 96. Treatment of Acute Abdominal Pain • Analgesics: – Though in past ER physicians did not treat acute abdominal pain with analgesics for fear of altering or obscuring the diagnosis, current literature favors the use of opoids judiciously in such patients.
  • 97. Treatment of Acute Abdominal Pain • Antibiotics: – Must be consider when treating suspected abdominal sepsis or diffuse peritonitis. – Coverage should be aimed at anaerobes and aerobic gram negatives. – If SBP suspected, must cover for gram positive aerobes. – Examples of mononotherapy are cefoxitin, cefotetan, ampicillin-sulbactam, or ticarcillin- clavulanate.
  • 98. Disposition of Acute Abdominal Pain • Indications for admissions: – Pts who appear ill. – Very young / Elderly – Immunocompromised – Unclear diagnosis – Intractable pain, nausea, or vomiting – Altered mental status – Those using drugs, alcohol, or that lack social support. – Pts with poor follow-up and/or noncompliant.
  • 99. Disposition of Acute Abdominal Pain • Non-specific abdominal pain – If this is the working diagnosis, patients must be re-examined in 24 hours. This may be done in the outpatient setting.
  • 100. References 1. SCHWARTZ'S PRINCIPLES OF SURGER 11th Edition 2. Bailey & Love's Short Practice of Surgery 26th edition 3. A manual of Clinical Surgery by S. Das : 8th Edition 4. https://emedicine.medscape.com/article/195976- overview 5. https://radiopaedia.org
  • 101. May Lord Dhanwantari bless us with sound health and protect from COVID-19