4. • Bionanotechnology is a division of
nanotechnology which uses biological starting
materials, and it keeps exciting opportunities to
bring high-impact advances in the field of
bioengineering and medicine.
• Currently one of the two progressive areas are
the biotechnology and nanotechnology, and
these two progressive fields combination will
form an interesting new field coined as
‘Bionanotechnology’.
5. • Bionanotechnology has become an fantastic field of
research and an area of technology development. It
offers at the nanoscale (100,000 times smaller than
the diameter of the average human hair) the ability
to provide insight into the structural features of
biological systems such as cell or tissue as well as to
develop nanobiomaterials/ medical units for
diagnostics, therapeutics and tissue regeneration.
• Ongoing work on bionanotechnology includes
development of nanoprobes that can characterize
the nanoscale structure and function of cells. This
article information is all about the current status of
bionanotechnology and its applications.
6.
7. Reserchers learn from biology to create new
micronanoscale devices to better understand life
Processes at the nanoscale.
Nano.the Greek word for “dwarf” indicates one
billionth of something.So, a nanometre is simply a
billionth of a metre.
The nanotechnology talks between 1 and
100nm.Some examples are, the dia of one hydrogen
atom is 0.1nm, width of DNA molecule is 2.5nm and
glucose is just below 1nm in size.
8. • Bionanotechnology is just a rapidly developing area of
scientific and technological opportunity that applies the
tools and processes of nano/microfabrication to build
devices for studying biosystems.
• It is also regarded as the area of study where
nanotechnology has applications in the field of biology
and medical sciences. It became one of the booming
and exciting research fields throughout the globe.
Nevertheless, in the past few years, there also have
been some great discoveries and inventions had
occured in these type of studies.
9. • “Nano” means dwarf in Greek
• Nanocsale : 1 nm = 1 x 10-9 m
Water
molecule
Nanodevices
Nanopores
Dendrimers
Nanotubes
Quantum dots
Nanoshells
White
blood cell
Tennis ball
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30. Applications of Different Nanoparticles
in Medicine
Liposomes
• Liposomes are phospholipid vesicles (50–100 nm)
• They have a bilayer membrane structure similar to that of
biological membranes and an internal aqueous phase
• Liposomes show excellent circulation, penetration and
diffusion properties
Dendrimers
• These are highly branched synthetic polymers (<15 nm)
• It show layered architectures constituted of a central
core, an internal region and numerous terminal groups
• Wide application in Drug Delivery System (DDS) and
gene delivery
Liposomes
Dendrimers
31. • Carbon nanotubes
• These are formed of coaxial graphite sheets (<100 nm)
rolled up into cylinders
• It exhibit excellent strength and electrical properties and
are efficient heat conductors
• Due to semiconductor nature of nanotubes are used as
biosensors
• Magnetic nanoparticles
• These are spherical nanocrystals of 10–20 nm of size
with a Fe2+ and Fe3+ core surrounded by dextran or
PEG molecules
• Their magnetic properties make them excellent agents
to label biomolecules in bioassays, as well as MRI
contrast agents
• Useful in targeted gene therapy.
Carbon nanotubes
Magnetic
nanoparticles
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34. Quantum dots
• These are colloidal fluorescent semiconductor
nanocrystals (2–10 nm)
• They are resistant to photobleaching and show
exceptional resistance to photo and chemical
degradation
• Quantum dots excellent contrast agents for
imaging and labels for bioassays
Gold nanoparticles
• These are one type of metallic nanoparticle of
size <50 nm
• These are prepared with different geometries,
such as nanospheres, nanoshells, nanorods or
nanocages
• These are excellent labels for biosensors
Quantum dots
Gold
nanoparticles
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42. ATOMIC FORCE MICROSCOPE
ATPASE MOTOR
BRAIN MACHINE INTERFACE
BIOCHEMICAL MOTOR
CARBON NANOTUBE
IMAGING DEVICES
NANOCHEMICAL OSCILATOR
RIBOSOMES AS NANOMEMORIES