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Obstetrics & Gynecology International Journal
Immediate Post Placental Insertion of IUD-The
Challenge to Solve the Expulsion Problem
Volume 2 Issue 5 - 2015
Dirk A Wildemeersch1
, Norman D Gold-
stuck2
and Dirk RG Janssens3
1
Gynecological Outpatient Clinic and IUD Training Center,
Belgium
2
Department of Obstetrics and Gynaecology, Stellenbosch
University, South Africa
3
Gynecological outpatient clinic, Belgium
*Corresponding author: Dirk A Wildemeersch,
Gynecological Outpatient Clinic and IUD Training Center,
Ghent, Belgium, Email: d.wildemeersch@skynet.be
Received: July 21, 2015 | Published: July 30, 2015
Editorial
expulsion problem by modifying existing devices, such as adding
absorbable sutures (Delta-T) or additional appendages. These
attempts did not appear beneficial. Post placental placement
of conventional IUDs during Cesarean section is associated
with lower expulsion rates when compared to immediate
postplacental vaginal insertion. Expulsion rates vary from
around 5% at 12 months to up to 50% and even higher if partial
expulsions are included in the analysis [4-6].
The risk of expulsion can be reduced substantially with
appropriate training in postpartum insertion techniques.
However, it appears that a simple and elegant solution to
minimize the number of expulsions is to simply attach the IUD to
the fundus of the uterus immediately postplacental.
An anchoring technique for use in the immediate postpartum
period was developed in Belgium in the 1980s and has been the
subject of extensive clinical research since 1985 at the University
in Ghent and in internationally conducted clinical trials [7-9].
Since its inception, the technology has passed through several
phases of improvement. The last version was the subject of
clinical trials conducted in China. The technique consisted in the
suspension of a frameless, copper-releasing IUD immediately in
the post placental uterus during Cesarean section. The anchor
consisted of a biodegradable cone (polycaprolactone) which
was added below the anchoring knot of the frameless IUD.
The objective was to study the effects of immediate insertion
of a frameless IUD during Cesarean section on the bleeding
pattern, duration of lochia and healing of uterus. Two hundred
women used the IUD and 204 women who did not use the IUD
served as the control group. Follow-up visit was performed at
42 days and 90 days after delivery. There was no significant
difference in postpartum hemorrhage, continuance of lochia,
and healing of uterus was normal. The expulsion rate was 4%
[10]. However, it was found that removal of the IUD was difficult
in a significant number of women due to the slow degradation
time of the cone material. It was concluded that further research
on the improvement of absorption time of the biodegradable
component may provide additional benefits of the retention
technology.
Recently, the technique of suspending the frameless IUD for
intracesarean insertion was further optimized. The technique
consists of the precise placement of the anchoring knot
immediately below the serosa of the uterus, followed by fixing
the knot in place with an absorbable suture. The IUD tail is
looped in the cervical canal and is cut prior to discharge from
the hospital. In case the tail is in the cavity, it usually can be
picked-up using a thin, 3 mm alligator forceps when removal is
requested. The anchoring technique has shown to be easy, quick
and safe in a pilot trial with no expulsions at 12 months. It was
readily apparent that the technique could be considered a major
advance, suitable for general use due to its simplicity requiring
limited training. The position of the anchor in the fundus of
the uterus can be identified using sonography by localizing
the stainless steel marker attached to the anchoring knot.
Although no removal studies have been conducted, removal of
the IUD is expected to be similar to the removal after interval
insertion of the device [11]. A modified technique is currently
been developed for insertion after vaginal delivery. We prefer
the frameless IUD over framed IUDs as the latter may cause
discrepancy with the uterine cavity and embedment during
involution of the uterus, particularly during prolonged lactation
as hyper involution in these women is not uncommon [12].
Uterine compatibility will dictate patient continuation rates
and overall patient acceptance. In addition, the availability of
adequate contraception immediately post Cesarean delivery
may have an added benefit in reducing the number of Cesarean
sections performed worldwide. By allowing for adequate timing
between pregnancies full uterine recover would be achieved
thus allowing women to achieve vaginal delivery. Studies have
shown that 40 to 80% of women can successful achieve vaginal
births after Cesarean section (VBAC) [13].
Further studies should be initiated related to new suspension
techniques as they appear to be the only solution to solve the
Submit Manuscript | http://medcraveonline.com Obstet Gynecol Int J 2014 2015, 2(5): 00052
Editorial
Immediate postpartum intrauterine device (IUD) insertion
deserves great attention as it can provide immediate
contraception and prevents repeat unintended pregnancies
[1]. Immediate post placental insertion (within 10 minutes of
deliveryoftheplacenta)ofcopper-bearingorhormone-releasing
IUDs is generally safe and acceptable, although compared
with interval insertion it carries a higher risk of expulsion,
thus affecting effectiveness and overall patient acceptance [2].
Women undergoing Cesarean section need contraception, as
an interdelivery interval shorter than 18 months is considered
a risk factor for uterine rupture [3]. In these women, a low
expulsion risk is therefore paramount.
Over the past decades attempts have been made to solve the
expulsion problem associated with postpartum insertion
of IUDs. They will also expand the method as a strategy to
reduce unintended pregnancy and rapid repeat pregnancy in
adolescents [14].
Conflict of interest
Dirk Wildemeersch has conducted clinical research in the
field of non-hormonal and hormonal, framed and frameless
intrauterine devices, including in postpartum women, for 30
years. Norman Goldstuck conducted research in intrauterine
device use, and published on intrauterine contraception
application during Cesarean section. Dirk Janssens participated
in clinical trials with frameless IUD inserted during Cesarean
section.
References
1.	 Rodriguez MI, Even M, Espey E (2014) Advocating for immediate
postpartum LARC: increasing access, improving outcomes, and
decreasing cost. Contraception 90(5): 468-471.
2.	 American College of Obstetricians and Gynecologists (2011) ACOG
Practice Bulletin No. 121: long-acting reversible contraception:
implants and intrauterine devices. Obstet Gynecol 118(1): 184-196.
3.	 Bujold E, Gauthier RJ (2010) Risk of Uterine Rupture Associated with
an Interdelivery Interval Between 18 and 24 Months. Obstet Gynecol
115(5): 1003-1006.
4.	 Kapp N, Curtis KM (2009) Intrauterine device insertion during the
postpartum period: a systematic review. Contraception 80(4): 327-
336.
5.	 Chi IC, Wilkens LR, Rogers S (1985) Expulsions in immediate
postpartum insertions of Lippes Loop D and Copper T IUDs and
their counterpart Delta devices -- an epidemiological analysis.
Contraception 32(2): 119-134.
6.	 Goldstuck ND, Steyn PS (2013) Intrauterine contraception after
cesarean section and during lactation: a systematic review. Int J
Womens Health 5: 811-818.
7.	 Thiery M, Van Kets H, Van der Pas H (1985) Immediate postplacental
IUD insertion: The expulsion problem. Contraception 31(4): 331-
349.
8.	 Van Kets H, Parewijck W, Kleinhout J, Osler M, Zighelboim I, et al.
(1991) Clinical experience with the Gyne-T postpartum intrauterine
device. Fertil Steril 55(6): 1144-1149.
9.	 Van Kets H, Parewijck W, Van der Pas H, Batár I, Creatsas G, et al.
(1993) Immediate postplacental insertion and fixation of the CuFix
postpartum implant system. Contraception 48(4): 349-357.
10.	Zhang H, Fang G, Zhou C (2004) Study on GyneFix PP IUD insertion
during cesarean section. Chinese Journal of Family Planning 12(8):
481-482.
11.	Batar I, Wildemeersch D (2004) The force required to remove an
anchored bioactive substance from the human uterus: results after
long-term use. Contraception 69(6): 501-503.
12.	El-Minawi MF, Foda MS (1971) Postpartum lactation amenorrhea:
endometrial pattern and reproductive ability. Am J Obstet Gynecol
111(1): 17-21.
13.	Stamilio DM, DeFranco E, Paré E, Odibo AO, Peipert JF, et al. (2007)
Short Interpregnancy Interval: Risk of Uterine Rupture and
Complications of Vaginal Birth after Caesarean Delivery. Obstet
Gynaecol 110(5): 1075-1082.
14.	Tocce KM, Sheeder JL, Teal SB (2012) Rapid repeat pregnancy in
adolescents: do immediate postpartum contraceptive implants make
a difference? Am J Obstet Gynecol 206(6): 481e1-481e7.
Immediate Post Placental Insertion of IUD-The Challenge to Solve the Expulsion Problem
Citation: Wildemeersch DA, Goldstuck ND, Janssens DRG (2015) Immediate Post Placental Insertion of IUD-The Challenge to Solve the Expulsion
Problem. Obstet Gynecol Int J 2014 2(5): 00052. DOI: 10.15406/ogij.2015.02.00052
2/2
Copyright:
©2015 Wildemeersch

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OGIJ-02-00052

  • 1. Obstetrics & Gynecology International Journal Immediate Post Placental Insertion of IUD-The Challenge to Solve the Expulsion Problem Volume 2 Issue 5 - 2015 Dirk A Wildemeersch1 , Norman D Gold- stuck2 and Dirk RG Janssens3 1 Gynecological Outpatient Clinic and IUD Training Center, Belgium 2 Department of Obstetrics and Gynaecology, Stellenbosch University, South Africa 3 Gynecological outpatient clinic, Belgium *Corresponding author: Dirk A Wildemeersch, Gynecological Outpatient Clinic and IUD Training Center, Ghent, Belgium, Email: d.wildemeersch@skynet.be Received: July 21, 2015 | Published: July 30, 2015 Editorial expulsion problem by modifying existing devices, such as adding absorbable sutures (Delta-T) or additional appendages. These attempts did not appear beneficial. Post placental placement of conventional IUDs during Cesarean section is associated with lower expulsion rates when compared to immediate postplacental vaginal insertion. Expulsion rates vary from around 5% at 12 months to up to 50% and even higher if partial expulsions are included in the analysis [4-6]. The risk of expulsion can be reduced substantially with appropriate training in postpartum insertion techniques. However, it appears that a simple and elegant solution to minimize the number of expulsions is to simply attach the IUD to the fundus of the uterus immediately postplacental. An anchoring technique for use in the immediate postpartum period was developed in Belgium in the 1980s and has been the subject of extensive clinical research since 1985 at the University in Ghent and in internationally conducted clinical trials [7-9]. Since its inception, the technology has passed through several phases of improvement. The last version was the subject of clinical trials conducted in China. The technique consisted in the suspension of a frameless, copper-releasing IUD immediately in the post placental uterus during Cesarean section. The anchor consisted of a biodegradable cone (polycaprolactone) which was added below the anchoring knot of the frameless IUD. The objective was to study the effects of immediate insertion of a frameless IUD during Cesarean section on the bleeding pattern, duration of lochia and healing of uterus. Two hundred women used the IUD and 204 women who did not use the IUD served as the control group. Follow-up visit was performed at 42 days and 90 days after delivery. There was no significant difference in postpartum hemorrhage, continuance of lochia, and healing of uterus was normal. The expulsion rate was 4% [10]. However, it was found that removal of the IUD was difficult in a significant number of women due to the slow degradation time of the cone material. It was concluded that further research on the improvement of absorption time of the biodegradable component may provide additional benefits of the retention technology. Recently, the technique of suspending the frameless IUD for intracesarean insertion was further optimized. The technique consists of the precise placement of the anchoring knot immediately below the serosa of the uterus, followed by fixing the knot in place with an absorbable suture. The IUD tail is looped in the cervical canal and is cut prior to discharge from the hospital. In case the tail is in the cavity, it usually can be picked-up using a thin, 3 mm alligator forceps when removal is requested. The anchoring technique has shown to be easy, quick and safe in a pilot trial with no expulsions at 12 months. It was readily apparent that the technique could be considered a major advance, suitable for general use due to its simplicity requiring limited training. The position of the anchor in the fundus of the uterus can be identified using sonography by localizing the stainless steel marker attached to the anchoring knot. Although no removal studies have been conducted, removal of the IUD is expected to be similar to the removal after interval insertion of the device [11]. A modified technique is currently been developed for insertion after vaginal delivery. We prefer the frameless IUD over framed IUDs as the latter may cause discrepancy with the uterine cavity and embedment during involution of the uterus, particularly during prolonged lactation as hyper involution in these women is not uncommon [12]. Uterine compatibility will dictate patient continuation rates and overall patient acceptance. In addition, the availability of adequate contraception immediately post Cesarean delivery may have an added benefit in reducing the number of Cesarean sections performed worldwide. By allowing for adequate timing between pregnancies full uterine recover would be achieved thus allowing women to achieve vaginal delivery. Studies have shown that 40 to 80% of women can successful achieve vaginal births after Cesarean section (VBAC) [13]. Further studies should be initiated related to new suspension techniques as they appear to be the only solution to solve the Submit Manuscript | http://medcraveonline.com Obstet Gynecol Int J 2014 2015, 2(5): 00052 Editorial Immediate postpartum intrauterine device (IUD) insertion deserves great attention as it can provide immediate contraception and prevents repeat unintended pregnancies [1]. Immediate post placental insertion (within 10 minutes of deliveryoftheplacenta)ofcopper-bearingorhormone-releasing IUDs is generally safe and acceptable, although compared with interval insertion it carries a higher risk of expulsion, thus affecting effectiveness and overall patient acceptance [2]. Women undergoing Cesarean section need contraception, as an interdelivery interval shorter than 18 months is considered a risk factor for uterine rupture [3]. In these women, a low expulsion risk is therefore paramount. Over the past decades attempts have been made to solve the
  • 2. expulsion problem associated with postpartum insertion of IUDs. They will also expand the method as a strategy to reduce unintended pregnancy and rapid repeat pregnancy in adolescents [14]. Conflict of interest Dirk Wildemeersch has conducted clinical research in the field of non-hormonal and hormonal, framed and frameless intrauterine devices, including in postpartum women, for 30 years. Norman Goldstuck conducted research in intrauterine device use, and published on intrauterine contraception application during Cesarean section. Dirk Janssens participated in clinical trials with frameless IUD inserted during Cesarean section. References 1. Rodriguez MI, Even M, Espey E (2014) Advocating for immediate postpartum LARC: increasing access, improving outcomes, and decreasing cost. Contraception 90(5): 468-471. 2. American College of Obstetricians and Gynecologists (2011) ACOG Practice Bulletin No. 121: long-acting reversible contraception: implants and intrauterine devices. Obstet Gynecol 118(1): 184-196. 3. Bujold E, Gauthier RJ (2010) Risk of Uterine Rupture Associated with an Interdelivery Interval Between 18 and 24 Months. Obstet Gynecol 115(5): 1003-1006. 4. Kapp N, Curtis KM (2009) Intrauterine device insertion during the postpartum period: a systematic review. Contraception 80(4): 327- 336. 5. Chi IC, Wilkens LR, Rogers S (1985) Expulsions in immediate postpartum insertions of Lippes Loop D and Copper T IUDs and their counterpart Delta devices -- an epidemiological analysis. Contraception 32(2): 119-134. 6. Goldstuck ND, Steyn PS (2013) Intrauterine contraception after cesarean section and during lactation: a systematic review. Int J Womens Health 5: 811-818. 7. Thiery M, Van Kets H, Van der Pas H (1985) Immediate postplacental IUD insertion: The expulsion problem. Contraception 31(4): 331- 349. 8. Van Kets H, Parewijck W, Kleinhout J, Osler M, Zighelboim I, et al. (1991) Clinical experience with the Gyne-T postpartum intrauterine device. Fertil Steril 55(6): 1144-1149. 9. Van Kets H, Parewijck W, Van der Pas H, Batár I, Creatsas G, et al. (1993) Immediate postplacental insertion and fixation of the CuFix postpartum implant system. Contraception 48(4): 349-357. 10. Zhang H, Fang G, Zhou C (2004) Study on GyneFix PP IUD insertion during cesarean section. Chinese Journal of Family Planning 12(8): 481-482. 11. Batar I, Wildemeersch D (2004) The force required to remove an anchored bioactive substance from the human uterus: results after long-term use. Contraception 69(6): 501-503. 12. El-Minawi MF, Foda MS (1971) Postpartum lactation amenorrhea: endometrial pattern and reproductive ability. Am J Obstet Gynecol 111(1): 17-21. 13. Stamilio DM, DeFranco E, Paré E, Odibo AO, Peipert JF, et al. (2007) Short Interpregnancy Interval: Risk of Uterine Rupture and Complications of Vaginal Birth after Caesarean Delivery. Obstet Gynaecol 110(5): 1075-1082. 14. Tocce KM, Sheeder JL, Teal SB (2012) Rapid repeat pregnancy in adolescents: do immediate postpartum contraceptive implants make a difference? Am J Obstet Gynecol 206(6): 481e1-481e7. Immediate Post Placental Insertion of IUD-The Challenge to Solve the Expulsion Problem Citation: Wildemeersch DA, Goldstuck ND, Janssens DRG (2015) Immediate Post Placental Insertion of IUD-The Challenge to Solve the Expulsion Problem. Obstet Gynecol Int J 2014 2(5): 00052. DOI: 10.15406/ogij.2015.02.00052 2/2 Copyright: ©2015 Wildemeersch