An ABX strategy involves focusing marketing and sales efforts on specific target accounts across their buyer's journey. The document discusses aligning teams around growth objectives, gaining buy-in, and executing and optimizing the strategy. It also covers identifying best opportunity accounts, taking a journey stage approach to engage accounts where they are in the buying process, and measuring key metrics to track engagement, pipeline, and ROI. The goal of an ABX strategy is to orchestrate relevant interactions between marketing and sales to close more deals.