1. !!EDUCATION AND PROFESSIONAL EXPERIENCE
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!TECHNIQUES
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Nov 2014-
Oct 2016
Postdoctoral fellowship- University of Maryland at College Park, USA
Briken lab.
!A) Anti-cancer activities of poorly water-soluble drugs solubilise by acyclic
cucurbit[n]uril container : In vitro and In vivo studies.
B) Biological characterisation of targeted nanoparticles.
Oct 2011-
Oct 2014
PhD student - University of Bordeaux, France
RMSB, CNRS UMR 5536, supervisor: Dr. Pierre Voisin
!A) Study of a new theranostic agent: the alkoxyamine; cellular mechanism of
apoptosis induction, imaging and effects on the immune response.
B) Characterization of the RGD ligand internalization by cancer cells for Magnetic
Resonance Imaging application.
C) Investigation of intratracheal injection of nanoparticles for passive glioma
targeting.
Teaching experience: Cell signalling course for BS students.
2009-2011 MSc in Immunology and Microbiology - University of Bordeaux, France
!Internship (6 months) at CIRID CNRS UMR 5164, supervisor: Dr. Julie
Dechanet-Merville : Regulatory function of γδ T cells in the interferon-γ
production.
!MSc in Cellular Biology and physiopathology - University of Bordeaux,
France
Internship (2 months) at Cardiovascular adaptation to the ischemia, INSERM
1034, supervisor: Dr. Alain-Pierre Gadeau : Development of RT-qPCR for M1 and
M2 macrophages markers quantification.
Tissue Culture Cell culture of adherent and non-adherent cells; Viability tests. Blood cells
separation by ficoll density gradient;
Immunology Flow cytometry (BD and Millipore cytometers) : Detection of viability, apoptosis,
mitochondrial perturbations and oxidative stress; Staining of immune cells (intra
and extracellular staining); ELISA; Magnetic cell separation.
Molecular
Biology
DNA and mRNA isolation; Subcloning; Pulse gel electrophoresis; Restriction
mapping; PCR and RT-qPCR.
Imaging Fluorescence microscopy (cell and tissue); Immunohistochemistry; Cryostat; in
vivo fluorescence imaging; MRI.
Biochemistry Western blot ; Peptides conjugation with fluorescent probes; HPLC (ion
exchange and affinity chromatography).
In vivo
techniques
Tumor implantation (orthotopic and subcutaneous); Intraperitoneal and
intravenous injection; Intracardiac blood collection; organ or tumor extraction.

2. PUBLICATIONS AND PATENTS
!!• Moncelet D, Voisin P, Koonjoo N, Bouchaud V, Massot P, Parzy E, Audran G, Franconi JM,
Thiaudière E, Marque S, Brémond P, Mellet P, « Alkoxyamines : first steps towards a new family
of theranostic agents against cancer ». Molecular Pharmaceutics, 2014.
• Moncelet D, Bouchaud V, Mellet P, Ribot E, Miraux S, Franconi JM, Voisin P. « Cellular density
effect on RGD ligand internalization in glioblastoma for MRI application ». Plos One, 2013
• Samanta K.S, Moncelet D, Briken V, Isaacs L. Metal Organic Polyhedra Capped with
Cucurbit[8]uril Delivers Doxorubicin to Cancer Cells. J Am Chem Soc, 2016.
• Bianchi A, Moncelet D, Lux F, Plissonneau M, Rizzitelli S, Ribot EJ, Tassali N, Bouchaud V,
Tillement O, Voisin P, Crémillieux Y. “Orotracheal administration of contrast agents: a new
protocol for brain tumor targeting ». NMR biomedicine, 2015.
• Sigwalt D, Moncelet D, Falcinelli S, Mandadapu V, Zavalij PY, Day A, Briken V, Isaacs L.
“Acyclic Cucurbit[n]uril-Type Molecular Containers: Influence of Linker Length on Their Function
as Solubilizing Agents”. ChemMedChem, 2016
• She N, Moncelet D, Gilberg L, Lu X, Sindelar V, Briken V, Isaacs L. Glycoluril-Derived Molecular
Clips are Potent and Selective Receptors for Cationic Dyes in Water. Chemistry, 2016.
• Hettiarachchi G, Samanta SK, Falcinelli S, Zhang B, Moncelet D, Isaacs L, Briken V. “Acyclic
Cucurbit[n]uril-Type Molecular Container Enables Systemic Delivery of Effective Doses of
Albendazole for Treatment of SK-OV-3 Xenograft Tumors”. Mol Pharm, 2016
• Parzy E, Bouchaud V, Massot P, Voisin P, Koonjoo N, Moncelet D, Franconi JM, Thiaudière E,
Mellet P. “Overhauser-enhanced MRI of elastase activity from in vitro neutrophil degranulation”.
Plos One, 2013.
• Patent pending : EP13305815.6. « Alkoxyamines for the treatment of cancers ». Mellet P,
Marque S, Franconi F, Voisin P, Moncelet D, Bremond P, Audran G.
LANGUAGE AND COMPUTER SKILLS!Languages: . French: native language
. English: professional proficiency
Expert in MS Office Pack, iWork (Pages, Keynote, Numbers), Graphpad prism, Photoshop,
imageJ, knowledge in bioinformatics
ORAL COMMUNICATION!
. Alkoxyamines : first steps towards a new family of theranostic agents against cancer. Moncelet
D, Voisin P, Koonjoo N, Bouchaud V, Massot P, Parzy E, Audran G, Franconi JM, Thiaudière E,
Marque S, Brémond P, Mellet P Journée de l’école doctorale, april 2014, Bordeaux, France.
POSTER
!!. Cellular density effect on RGD ligand internalization in glioblastoma for MRI application.
Moncelet D, Bouchaud V, Mellet P, Ribot E, Miraux S, Franconi JM, Voisin P. Symposium of the
French club of glial cells, March 2014, Marseille, France and Journée de l’école doctorale, april
2013, Bordeaux, France.