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Nano4Health
February 14th 2017
Lieve Apers Coordinator Nano4Health
Introduction
• Clusters and Entrepreneurship in Support of EmergingClusters and Entrepreneurship in Support of EmergingClusters and Entrepreneurship in Support of EmergingClusters and Entrepreneurship in Support of Emerging
IndustriesIndustriesIndustriesIndustries –––– CIP call 2013CIP call 2013CIP call 2013CIP call 2013
• 6 projects were selected:6 projects were selected:6 projects were selected:6 projects were selected:
Poly4EmIPoly4EmIPoly4EmIPoly4EmI
LoToNoLoToNoLoToNoLoToNo
INNOINNOINNOINNO----SMARTSMARTSMARTSMART
Health2CareHealth2CareHealth2CareHealth2Care
C3C3C3C3----SaxonySaxonySaxonySaxony
Nano4HealthNano4HealthNano4HealthNano4Health
Goal
SupportSupportSupportSupport emerging industries in the domain ofemerging industries in the domain ofemerging industries in the domain ofemerging industries in the domain of
personalised healthcarepersonalised healthcarepersonalised healthcarepersonalised healthcare atatatat the crossroads ofthe crossroads ofthe crossroads ofthe crossroads of
nanoelectronicsnanoelectronicsnanoelectronicsnanoelectronics and biotechnologyand biotechnologyand biotechnologyand biotechnology
Embedded in societal changes
Ecosystem Nano4Health
Objectives
---- Developing cross cluster policy guideliDeveloping cross cluster policy guideliDeveloping cross cluster policy guideliDeveloping cross cluster policy guidelinesnesnesnes
---- Support SMEs in emerging industriesSupport SMEs in emerging industriesSupport SMEs in emerging industriesSupport SMEs in emerging industries
Nano4Health InnotrackNano4Health InnotrackNano4Health InnotrackNano4Health Innotrack
Large scaleLarge scaleLarge scaleLarge scale
demonstratordemonstratordemonstratordemonstrator
---- Strengthening of clusters andStrengthening of clusters andStrengthening of clusters andStrengthening of clusters and
collaborationscollaborationscollaborationscollaborations
Network eventsNetwork eventsNetwork eventsNetwork events
MatchmakingMatchmakingMatchmakingMatchmaking
B2B, A2B,,,,B2B, A2B,,,,B2B, A2B,,,,B2B, A2B,,,,
(inter)national cluster(inter)national cluster(inter)national cluster(inter)national cluster
exchangeexchangeexchangeexchange
Our collaboration model
SMESMESMESME
ResearchResearchResearchResearch
UserUserUserUser
Our approach
Multidisciplinary approach
The Spider approach
Fast Track to Innovation
3 phases
Challenge – call for projects
Competence – requests for competences
Solution
• Get acquainted workshop
• Business model workshop (mixed groups)
• Story Telling
Individual coaches of the cluster organisations
Combination of vouchers, KMO wallet and …
The Spider approach
Case
Phoreon
a brand of Pharma Diagnostics NV (SME)
Gold has many faces. Once it is reduced to extreme small sizes (nanoscale) and presented in specific
structures extraordinary characteristics of this nobel metal start to emerge. Unique features appear
then that open avenues for cancer therapies. This application is under full investigation in research
labs worldwide and slowly finds its way to the clinic. A key aspect for those applications is the
quality of the gold nanostructure.
Phoreon is a Belgium based, Flemish SME, with research labs and headquarters in the bio-incubator
of Leuven. The R&D team consists amongst others of chemists, biochemists and physicists with
expertises in Nanomaterial Sciences. They have a proprietary production process that delivers high
quality gold nanostructures. Moreover, they have strong links with Life Technology disciplines like
biotechnology and cell biology. Altogether, this puts them in a unique position to achieve the high
quality standards researchers require for this application.
www.phoreon.com
1. Company
1111 TechnologyTechnologyTechnologyTechnology
3333 MarketsMarketsMarketsMarkets
1111 needneedneedneed ==== high quality + lower costhigh quality + lower costhigh quality + lower costhigh quality + lower cost
Sales Premium Products
Premium resources
Broaden the application fieldBroaden the application fieldBroaden the application fieldBroaden the application field::::
• Scientific ResearchScientific ResearchScientific ResearchScientific Research
• Other industriesOther industriesOther industriesOther industries
Service: Technology
Platform
Medicine discovery
Drug Discovery ScreeningsDrug Discovery ScreeningsDrug Discovery ScreeningsDrug Discovery Screenings::::
• Faster (HighFaster (HighFaster (HighFaster (High----ThrougputThrougputThrougputThrougput))))
• Cheaper (standard lab equipment)Cheaper (standard lab equipment)Cheaper (standard lab equipment)Cheaper (standard lab equipment)
• »»»» SoPRanoSoPRanoSoPRanoSoPRano
Home-use
Enable you to monitor your health:Enable you to monitor your health:Enable you to monitor your health:Enable you to monitor your health:
• WHEN you wantWHEN you wantWHEN you wantWHEN you want
• WHERE you wantWHERE you wantWHERE you wantWHERE you want
Sales; Multi parameter
Chips/reading devices
2. The Nano4Health challenges
Competition analysis for nanomaterial offeringsCompetition analysis for nanomaterial offeringsCompetition analysis for nanomaterial offeringsCompetition analysis for nanomaterial offerings
• Globally 10 direct competitors (nanomaterial experts)
• Produce + sell - poor links with Life Tech industry (except 1)
• Many link to publications on their website - poor in Testimonials
Competitor A
FactFactFactFact
• Phoreon’s nanomaterial quality exceeds competition
• Current website is outdated
• We need scientific content to create awareness & pull strategy on our websiteWe need scientific content to create awareness & pull strategy on our websiteWe need scientific content to create awareness & pull strategy on our websiteWe need scientific content to create awareness & pull strategy on our website
ProblemProblemProblemProblem
• Knowledge of Life Tech techniques is on board
• No hands-on expertise, no equipment
SolutionSolutionSolutionSolution
• Partnering with Centres of competence at the Nanotech/Life Science interface
3. Service providers
Our GNR
+
Competitor’s GNR
Kinetics Uptake in live cells
Immunogenicity
Material characterisation
GNR as label-free carrier for cell delivery of biologics (SHG)
Tumor therapy
Creativity
4. Outcome and impact
Level 4Level 4Level 4Level 4
1. Contract
2. Letter of Intent
Contracts/grants
Level 3Level 3Level 3Level 3
Company 1
Company 2
Networking
Level 5Level 5Level 5Level 5
Internal
1. Awareness of other parameters
2. Impact on our production process
3. Internal organisation
Level 1Level 1Level 1Level 1Level 2Level 2Level 2Level 2
N4HN4H-perimeter
5. Learnings
We have missed the legal framework
Thanks for the 6,500€/service provider, but it is a bit tight (for Life Tech laboratory testing)
AcademicAcademicAcademicAcademic InvestorsInvestorsInvestorsInvestors
ClustersClustersClustersClusters EntrepreneursEntrepreneursEntrepreneursEntrepreneurs
PolicyPolicyPolicyPolicy UsersUsersUsersUsers
Our cross sectoral ecosystem
The solution?
Evaluation and Impact
Validation
ecosystem
evidence and success indicators for sustainable
policies
fit insights into the N4Hmodel
optimization on a international level
Lessons
Learned
Learnings and outcomes
Multidisciplinary learning is key
In business model development
Towards future training trajectories
In application of creative industries
Cross fertilisation with creative industries could/should start earlier to enhance
ambition
Every multidisciplinary approach should aim to integrate technology, business
innovation and creative concepts
What is the innovation
How can we make money out of it
How can we get commitment from the user
Learnings and outcomes
It does not stop here
XKet4Health, Health Cluster
Expansion over other technology platforms (ICT, 3D printing)
Life Sciences and micro-electronics will only come together in completely new
business models where both business platforms dare to walk away from the existing
business dogma’s.
Awareness with technology/business developers
Awareness with competence providers/financiers
Learnings and outcomes
Flanders is a global technology leader in multidisciplinary technology platform based
business development
IMEC/Iminds, VIB
FlandersBio, DSP Valley
We represent one of the largest combined innovative business hubs in
ICT/Microelectronics/life sciences domain applications
We are developing a vision towards a world leading hub on health applications
Learnings
(Flanders Innovation and Entrepreneurship)
It is important to build up a structured process and governance to accommodate
multi-stakeholders, multi-discipline and multi-sector collaboration for tackling systemic
challenges.
A lean and iterative approach allowing for learning by doing and pivoting would be
inevitable in designing and establishing a collaborative model across different sectors.
Special consideration should be given to creative techniques to encourage
participants to co-inspire and co-innovate to find solutions and break out of traditional
technological driven thinking.
Learnings
(Flanders Innovation and Entrepreneurship)
A sound business case rooted in a concrete market opportunity is a key to drive the
collaboration between stakeholders across multi-sectors.
It is necessary to establish and apply a structured impact measurement & evaluation
process on all the levels of the model.
To tackle societal challenge and drive the systemic change forward the establishment
of an inclusive value chain focused on solutions with all the relevant stakeholders is
apparent to make it sustainable.
MOU
Cluster Directors:
FlandersBio- Henk Joos
FlandersDC – Pascal Cools
DSPValley – Peter Simkens
Awards
Highest potential for:
1. Internationalisation
2. Economical added value
3. Societal added value
4. Create New Value
5. Shape a new ecosystem approach
Internationalisation - Applied Maths
Economical added value
Trinean
Societal added value
Sneeze
Create or Shape New Value
BiosenSource
Shape a new ecosystem approach
Phoreon

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Nano4Health

  • 1. Nano4Health February 14th 2017 Lieve Apers Coordinator Nano4Health
  • 2. Introduction • Clusters and Entrepreneurship in Support of EmergingClusters and Entrepreneurship in Support of EmergingClusters and Entrepreneurship in Support of EmergingClusters and Entrepreneurship in Support of Emerging IndustriesIndustriesIndustriesIndustries –––– CIP call 2013CIP call 2013CIP call 2013CIP call 2013 • 6 projects were selected:6 projects were selected:6 projects were selected:6 projects were selected: Poly4EmIPoly4EmIPoly4EmIPoly4EmI LoToNoLoToNoLoToNoLoToNo INNOINNOINNOINNO----SMARTSMARTSMARTSMART Health2CareHealth2CareHealth2CareHealth2Care C3C3C3C3----SaxonySaxonySaxonySaxony Nano4HealthNano4HealthNano4HealthNano4Health
  • 3.
  • 4. Goal SupportSupportSupportSupport emerging industries in the domain ofemerging industries in the domain ofemerging industries in the domain ofemerging industries in the domain of personalised healthcarepersonalised healthcarepersonalised healthcarepersonalised healthcare atatatat the crossroads ofthe crossroads ofthe crossroads ofthe crossroads of nanoelectronicsnanoelectronicsnanoelectronicsnanoelectronics and biotechnologyand biotechnologyand biotechnologyand biotechnology
  • 7. Objectives ---- Developing cross cluster policy guideliDeveloping cross cluster policy guideliDeveloping cross cluster policy guideliDeveloping cross cluster policy guidelinesnesnesnes ---- Support SMEs in emerging industriesSupport SMEs in emerging industriesSupport SMEs in emerging industriesSupport SMEs in emerging industries Nano4Health InnotrackNano4Health InnotrackNano4Health InnotrackNano4Health Innotrack Large scaleLarge scaleLarge scaleLarge scale demonstratordemonstratordemonstratordemonstrator ---- Strengthening of clusters andStrengthening of clusters andStrengthening of clusters andStrengthening of clusters and collaborationscollaborationscollaborationscollaborations Network eventsNetwork eventsNetwork eventsNetwork events MatchmakingMatchmakingMatchmakingMatchmaking B2B, A2B,,,,B2B, A2B,,,,B2B, A2B,,,,B2B, A2B,,,, (inter)national cluster(inter)national cluster(inter)national cluster(inter)national cluster exchangeexchangeexchangeexchange
  • 9.
  • 12. The Spider approach Fast Track to Innovation 3 phases Challenge – call for projects Competence – requests for competences Solution • Get acquainted workshop • Business model workshop (mixed groups) • Story Telling Individual coaches of the cluster organisations Combination of vouchers, KMO wallet and …
  • 14. Case Phoreon a brand of Pharma Diagnostics NV (SME) Gold has many faces. Once it is reduced to extreme small sizes (nanoscale) and presented in specific structures extraordinary characteristics of this nobel metal start to emerge. Unique features appear then that open avenues for cancer therapies. This application is under full investigation in research labs worldwide and slowly finds its way to the clinic. A key aspect for those applications is the quality of the gold nanostructure. Phoreon is a Belgium based, Flemish SME, with research labs and headquarters in the bio-incubator of Leuven. The R&D team consists amongst others of chemists, biochemists and physicists with expertises in Nanomaterial Sciences. They have a proprietary production process that delivers high quality gold nanostructures. Moreover, they have strong links with Life Technology disciplines like biotechnology and cell biology. Altogether, this puts them in a unique position to achieve the high quality standards researchers require for this application. www.phoreon.com
  • 15. 1. Company 1111 TechnologyTechnologyTechnologyTechnology 3333 MarketsMarketsMarketsMarkets 1111 needneedneedneed ==== high quality + lower costhigh quality + lower costhigh quality + lower costhigh quality + lower cost Sales Premium Products Premium resources Broaden the application fieldBroaden the application fieldBroaden the application fieldBroaden the application field:::: • Scientific ResearchScientific ResearchScientific ResearchScientific Research • Other industriesOther industriesOther industriesOther industries Service: Technology Platform Medicine discovery Drug Discovery ScreeningsDrug Discovery ScreeningsDrug Discovery ScreeningsDrug Discovery Screenings:::: • Faster (HighFaster (HighFaster (HighFaster (High----ThrougputThrougputThrougputThrougput)))) • Cheaper (standard lab equipment)Cheaper (standard lab equipment)Cheaper (standard lab equipment)Cheaper (standard lab equipment) • »»»» SoPRanoSoPRanoSoPRanoSoPRano Home-use Enable you to monitor your health:Enable you to monitor your health:Enable you to monitor your health:Enable you to monitor your health: • WHEN you wantWHEN you wantWHEN you wantWHEN you want • WHERE you wantWHERE you wantWHERE you wantWHERE you want Sales; Multi parameter Chips/reading devices
  • 16. 2. The Nano4Health challenges Competition analysis for nanomaterial offeringsCompetition analysis for nanomaterial offeringsCompetition analysis for nanomaterial offeringsCompetition analysis for nanomaterial offerings • Globally 10 direct competitors (nanomaterial experts) • Produce + sell - poor links with Life Tech industry (except 1) • Many link to publications on their website - poor in Testimonials Competitor A FactFactFactFact • Phoreon’s nanomaterial quality exceeds competition • Current website is outdated • We need scientific content to create awareness & pull strategy on our websiteWe need scientific content to create awareness & pull strategy on our websiteWe need scientific content to create awareness & pull strategy on our websiteWe need scientific content to create awareness & pull strategy on our website ProblemProblemProblemProblem • Knowledge of Life Tech techniques is on board • No hands-on expertise, no equipment SolutionSolutionSolutionSolution • Partnering with Centres of competence at the Nanotech/Life Science interface
  • 17. 3. Service providers Our GNR + Competitor’s GNR Kinetics Uptake in live cells Immunogenicity Material characterisation GNR as label-free carrier for cell delivery of biologics (SHG) Tumor therapy Creativity
  • 18. 4. Outcome and impact Level 4Level 4Level 4Level 4 1. Contract 2. Letter of Intent Contracts/grants Level 3Level 3Level 3Level 3 Company 1 Company 2 Networking Level 5Level 5Level 5Level 5 Internal 1. Awareness of other parameters 2. Impact on our production process 3. Internal organisation Level 1Level 1Level 1Level 1Level 2Level 2Level 2Level 2 N4HN4H-perimeter
  • 19. 5. Learnings We have missed the legal framework Thanks for the 6,500€/service provider, but it is a bit tight (for Life Tech laboratory testing)
  • 23. Validation ecosystem evidence and success indicators for sustainable policies fit insights into the N4Hmodel optimization on a international level
  • 25. Learnings and outcomes Multidisciplinary learning is key In business model development Towards future training trajectories In application of creative industries Cross fertilisation with creative industries could/should start earlier to enhance ambition Every multidisciplinary approach should aim to integrate technology, business innovation and creative concepts What is the innovation How can we make money out of it How can we get commitment from the user
  • 26. Learnings and outcomes It does not stop here XKet4Health, Health Cluster Expansion over other technology platforms (ICT, 3D printing) Life Sciences and micro-electronics will only come together in completely new business models where both business platforms dare to walk away from the existing business dogma’s. Awareness with technology/business developers Awareness with competence providers/financiers
  • 27. Learnings and outcomes Flanders is a global technology leader in multidisciplinary technology platform based business development IMEC/Iminds, VIB FlandersBio, DSP Valley We represent one of the largest combined innovative business hubs in ICT/Microelectronics/life sciences domain applications We are developing a vision towards a world leading hub on health applications
  • 28. Learnings (Flanders Innovation and Entrepreneurship) It is important to build up a structured process and governance to accommodate multi-stakeholders, multi-discipline and multi-sector collaboration for tackling systemic challenges. A lean and iterative approach allowing for learning by doing and pivoting would be inevitable in designing and establishing a collaborative model across different sectors. Special consideration should be given to creative techniques to encourage participants to co-inspire and co-innovate to find solutions and break out of traditional technological driven thinking.
  • 29. Learnings (Flanders Innovation and Entrepreneurship) A sound business case rooted in a concrete market opportunity is a key to drive the collaboration between stakeholders across multi-sectors. It is necessary to establish and apply a structured impact measurement & evaluation process on all the levels of the model. To tackle societal challenge and drive the systemic change forward the establishment of an inclusive value chain focused on solutions with all the relevant stakeholders is apparent to make it sustainable.
  • 30. MOU Cluster Directors: FlandersBio- Henk Joos FlandersDC – Pascal Cools DSPValley – Peter Simkens
  • 31.
  • 32. Awards Highest potential for: 1. Internationalisation 2. Economical added value 3. Societal added value 4. Create New Value 5. Shape a new ecosystem approach
  • 33. Internationalisation - Applied Maths Economical added value Trinean Societal added value Sneeze Create or Shape New Value BiosenSource Shape a new ecosystem approach Phoreon