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New Products in 2012

 The New TripleQuad™ 6500 & QTRAP® 6500
 Systems
 with IonDrive™ Technology




                             The new AB SCIEX 6500 Series with
                             multi-component IonDrive™ Technology
                             AB SCIEX’s most sensitive triple quad
                             •   up to 10X increase in sensitivity
                             •   Up to 20X increase in detector
                                 dynamic range
                             - all with no compromise in mass range.

 1                                                          © 2012 AB SCIEX
IonDrive™ Technology Key Innovations
IonDrive™ Turbo V Source   IonDrive™ QJet Guide     IonDrive™ HE Detector




 Driving Performance by Driving More Ions While Maintaining Ruggedness

      Higher sensitivity
      Extended mass range m/z 5 – 2,000 with advanced dual RF
      electronics
      Extended dynamic range
      SelexION™ technology compatible
      Faster MRM3
  2                                                              © 2012 AB SCIEX
IonDrive™ Turbo V Source – Produce More Ions




    Original Turbo V™   New IonDrive Turbo V
3                                          © 2012 AB SCIEX
IonDrive™ QJet Ion Guide – A Dual Stage RF Ion
Guide




    Computed gas flow model showing flow through the ion guide
    Larger diameter of first stage  Better ion capture
    Smaller diameter of second stage  Better focusing into Q0
    End Result: More ions transmitted, fewer neutrals reaching Q0
4                                                           © 2012 AB SCIEX
Two Software Selectable Mass Ranges




5                                     © 2012 AB SCIEX
New Products in 2012

SelexION™ Technology - A higher level of Selectivity
      Salmeterol without SelexION   Salmeterol with SelexION


                    S/N = 3
                                              S/N = 252




  6                                                            © 2012 AB SCIEX
New Products in 2012

 ekspert™ microLC 200


                        The world’s only dedicated
                        micro-UHPLC designed to
                        deliver up to fivefold faster
                        separations and up to
                        fourfold improved sensitivity
                        • Reduction in mobile phase
                          costs up to 95%
                        • Designed specifically for
                          high throughput mass
                          spectrometry laboratories
                        • Ideal for pharmaceutical
                          applications – small
                          molecules and biologics

 7                                              © 2012 AB SCIEX

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07 new ab sciex products - triple quad™ 6500 qtrap 6500 systems and ekspert tm microlc 200-yuan-qing xia - ab sciex

  • 1. New Products in 2012 The New TripleQuad™ 6500 & QTRAP® 6500 Systems with IonDrive™ Technology The new AB SCIEX 6500 Series with multi-component IonDrive™ Technology AB SCIEX’s most sensitive triple quad • up to 10X increase in sensitivity • Up to 20X increase in detector dynamic range - all with no compromise in mass range. 1 © 2012 AB SCIEX
  • 2. IonDrive™ Technology Key Innovations IonDrive™ Turbo V Source IonDrive™ QJet Guide IonDrive™ HE Detector Driving Performance by Driving More Ions While Maintaining Ruggedness Higher sensitivity Extended mass range m/z 5 – 2,000 with advanced dual RF electronics Extended dynamic range SelexION™ technology compatible Faster MRM3 2 © 2012 AB SCIEX
  • 3. IonDrive™ Turbo V Source – Produce More Ions Original Turbo V™ New IonDrive Turbo V 3 © 2012 AB SCIEX
  • 4. IonDrive™ QJet Ion Guide – A Dual Stage RF Ion Guide Computed gas flow model showing flow through the ion guide Larger diameter of first stage  Better ion capture Smaller diameter of second stage  Better focusing into Q0 End Result: More ions transmitted, fewer neutrals reaching Q0 4 © 2012 AB SCIEX
  • 5. Two Software Selectable Mass Ranges 5 © 2012 AB SCIEX
  • 6. New Products in 2012 SelexION™ Technology - A higher level of Selectivity Salmeterol without SelexION Salmeterol with SelexION S/N = 3 S/N = 252 6 © 2012 AB SCIEX
  • 7. New Products in 2012 ekspert™ microLC 200 The world’s only dedicated micro-UHPLC designed to deliver up to fivefold faster separations and up to fourfold improved sensitivity • Reduction in mobile phase costs up to 95% • Designed specifically for high throughput mass spectrometry laboratories • Ideal for pharmaceutical applications – small molecules and biologics 7 © 2012 AB SCIEX

Notas do Editor

  1. Selecting the mass range of 1250 will provide the best low-mass sensitivity for applications involving singly-charged drugs and metabolites. Selecting the mass range of 2000 will provide a mass range more suitable for proteomics applications where low-mass sensitivity is less important.