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CRC Press is an imprint of the
Taylor & Francis Group, an informa business
Boca Raton London NewYork
DILIP GHOSH • SHANTANU DAS
DEBASIS BAGCHI • R.B. SMARTA
E d i t e d b y
Cover credit:  Aarti Paradkar
CRC Press
Taylor  Francis Group
6000 Broken Sound Parkway NW, Suite 300
Boca Raton, FL 33487-2742
© 2013 by Taylor  Francis Group, LLC
CRC Press is an imprint of Taylor  Francis Group, an Informa business
No claim to original U.S. Government works
Version Date: 20120813
International Standard Book Number-13: 978-1-4398-6269-8 (eBook - PDF)
This book contains information obtained from authentic and highly regarded sources. Reasonable efforts have been made to
publish reliable data and information, but the author and publisher cannot assume responsibility for the validity of all materials
or the consequences of their use. The authors and publishers have attempted to trace the copyright holders of all material repro-
duced in this publication and apologize to copyright holders if permission to publish in this form has not been obtained. If any
copyright material has not been acknowledged please write and let us know so we may rectify in any future reprint.
Except as permitted under U.S. Copyright Law, no part of this book may be reprinted, reproduced, transmitted, or utilized in any
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Dedicated to those people who made this world beautiful
through their innovations
Dilip Ghosh
Dedicated to my beloved teacher, Professor Mihir N. Das, DSc,
Jadavpur University
Debasis Bagchi
Dedicated to my beloved family
Shantanu Das
Dedicated to my beloved mother, who allowed me to explore
new avenues in life
R.B. Smarta
vii
Contents
Preface...............................................................................................................................................xi
Editors............................................................................................................................................. xiii
Contributors......................................................................................................................................xv
SECTION I  Introduction
Chapter 1	 Innovation Journey: How to Improve RD Leverage and Speed to Market................3
Dilip Ghosh, Shantanu Das, Debasis Bagchi, and R.B. Smarta
Chapter 2	 Innovations in Functional Food Industry for Health and Wellness..............................5
Parigi Ramesh Kumar and V. Prakash
Chapter 3	 Developments and Innovations in Dietary Supplements and Functional Foods.........13
M.L. Shankaranarayana, Jayant Deshpande, and Abhijit Bhattacharya
Chapter 4	 Innovation in Food Safety and Regulation..................................................................43
Kalpagam Polasa and B. Sesikeran
Chapter 5	 Creating and Establishing Networks for the Commercialization of Innovations.......57
Leena Aarikka-Stenroos and Birgitta Sandberg
SECTION II  Market and Trends
Chapter 6	 Regulation and Marketing of Nutraceuticals and Functional Foods
in Europe: The Broader Impact of Nutrition and Health Claims Regulation.............75
Patrick Coppens
Chapter 7	 Market and Marketing of Functional Foods and Dietary
	 Supplements in America������������������������������������������������������������������������������������������ 103
Philip E. Apong
Chapter 8	 Dairy Innovations and Market Growth in India....................................................... 113
Raka Saxena, A.K. Srivastava, and A.K. Singh
viii Contents
Chapter 9	 Changing Global Food Consumption Patterns: An Economic Perspective..............125
Srikanta Chatterjee
Chapter 10	 Influence of Regulations on the Commercialization and Marketing of Functional
Foods and Nutraceuticals in Canada and the United States .................................... 141
Lina Paulionis, Alex Kocenas, Manki Ho, Karen Ly, Larry McGirr,
and Ilana Platt
SECTION III  Consumer Perspective on Innovation versus Need
Chapter 11	 Functional Food Trends in India............................................................................... 165
Rekha R. Mallia
Chapter 12	 New Approaches for Foods and Nutrition for the Bottom of the Pyramid
(Gandhi’s Vision)....................................................................................................... 169
Ashok Vaidya
Chapter 13	 Consumer Reactions to Health Claims on Food Products........................................ 179
Klaus G. Grunert and Lisa Lähteenmäki
SECTION IV Technological Development on Healthy and
Functional Foods
Chapter 14	 Effect of Processing on Nutrients in Foods............................................................... 193
Fanbin Kong and R. Paul Singh
Chapter 15	 Requirements for Innovative Food Packaging.......................................................... 215
Kata Galic´
Chapter 16	 Innovation in Iron Fortification: Is the Future in Iron-Binding Milk Proteins?.......249
Ashling Ellis, Vikas Mittal, and Maya Sugiarto
Chapter 17	 Stabilization of Probiotics for Industrial Application...............................................269
Devastotra Poddar, Arup Nag, Shantanu Das, and Harjinder Singh
Chapter 18	 Application of Radio Frequency for Military Group Ration Food Package.............305
K. Luechapattanaporn, Y. Wang, J. Wang, J. Tang, L.M. Hallberg, and
C.P. Dunne
ixContents
Chapter 19	 Interaction between Food Components and the Innovation Pipeline....................... 319
Alistair Carr
Chapter 20	 Innovation in Technology Development with Reference to Enzymatic
Extraction of Flavonoids........................................................................................... 331
Munish Puri and Madan Lal Verma
Chapter 21	 Novel Extraction Technology for Antioxidants and Phytochemicals.......................343
Rajshri Roy, Kerrie Close, and Dilip Ghosh
SECTION V  Innovation in Functional Food Ingredients
Chapter 22	 Advances in Milk Protein Ingredients......................................................................363
Thom Huppertz and Hasmukh Patel
Chapter 23	 Probiotics as Functional Food Ingredients for Augmenting Human Health.............387
Sunita Grover, Ashwani Kumar, A.K. Srivastava, and Virender K. Batish
Chapter 24	 Omega-3 Polyunsaturated Fatty Acids: Basic and Contemporary
	 Research Issues......................................................................................................... 419
Melinda Phang, Melissa Fry, and Manohar L. Garg
Chapter 25	 Assessment of Polyphenol-Rich Foods and Beverages on Endothelial
(Vascular) Function in Healthy Humans................................................................... 435
Mark L. Dreher
Chapter 26	 Traditional Understanding, Modern Science, and Usage of Herbal
Medicine for Diabetes............................................................................................... 455
Dennis Chang, Srinivas Nammi, and Suzanne Grant
SECTION VI  Market to Innovative Products
Chapter 27	 Drivers and Barriers for Marketing Innovative Functional Food Products..............477
Ruth D’Souza
Chapter 28	 Marketing, PR, Advertising, and Media for Brand Building of Innovative
Foods and Nutritional Products.................................................................................485
M.G. Parameswaran
x Contents
Chapter 29	 Financial Implications of Innovations.......................................................................495
Girish P. Jakhotiya
Chapter 30	 Market-Focused Innovation in Food and Nutrition...................................................509
R.B. Smarta
SECTION VII  Future Trends
Chapter 31	 Innovation in Food Tourism and Product Distribution.............................................523
Timothy J. Lee, Tin-Chung Huang, and Kuan-Huei Lee
Chapter 32	 Regulations and Innovations Interphase................................................................... 531
D.B. Anantha Narayana
Chapter 33	 Nano-Functional Foods: Nanotechnology, Nutritional Engineering,
and Nutritionally Reductive Food Marketing...........................................................547
Gyorgy Scrinis and Kristen Lyons
Chapter 34	 Sustainability of Local Food Production: A Review on Energy and
Environmental Perspectives...................................................................................... 555
Sumita Ghosh
Index .............................................................................................................................................. 581
xi
Preface
Our new book Innovation in Healthy and Functional Foods endeavors to integrate two key contem-
porary concepts “innovation” and “functional and healthy foods,” the major thrust in the world of
food, nutrition, and nutraceuticals.
This book includes topics that have been researched in academia but have the potential to be
applied in the food industry. The question arises in mind as to which step in the innovation process
would be ideal for academia–industry collaboration. The collaboration may take place at any step
in the innovation process, that is, ideation, feasibility, development, commercialization, and launch.
However, we think the most ideal point is at stage zero, that is, even before a particular project has
been conceived. At this stage, as the industry scans the consumers’ needs and desires it can also
scan the new technologies, solutions, and capabilities available within academia. It is always hard to
decide when to adopt a technology from academic research into industrial development. Though
there is no strict rule yet it can be said that an organization with strong RD may adopt a technology
in its initial stage and develop it further. On the other hand for a market-driven organization it is
more convenient to adopt a mature technology. All these innovation concepts, though based on stud-
ies in multiple industries, can be successfully applied to the food industry.
The focus on food science and technology has transformed over centuries. In the past, the focus
of food science and technology was food security. This resulted in rapid improvement in agricul-
tural production techniques. Then the focus shifted to food safety and as a result a range of food
preservation techniques were developed. Once the food was proven safe, the taste, flavor, texture,
appearance, and other sensorial attributes of the food became the priority of the food industry to
satisfy consumer acceptance. After the development of safe and tasty foods, the focus of food sci-
ence and technology shifted toward healthy and functional foods. Functional food is defined as food
capable of providing health benefits beyond basic nutrition. Today, consumers desire foods that are
capable of playing not only a “health-promoting” but also a “disease-preventing” role, over and
above their routine function of supporting growth and maintenance.
A functional food may be of four types: (1) a natural food in which one of the components has
been naturally present at relatively high concentrations; (2) a food to which a component has been
added to provide benefits; (3) a food from which a component has been removed so that the food has
less adverse health effects; and (4) a food in which the absorption of one or more components has
been increased to prove a beneficial effect. This book focuses mainly on the type 2 functional food
and conducts a fairly detail exploration into the functional ingredients (e.g., omega-3, probiotics,
protein, iron, etc.) and their delivery techniques into consumer foods.
Innovation in functional and healthy foods can be carried out successfully only by a cross-
functional team as expertise in various subjects is required to be integrated. To be able to deliver
the innovation process to the food industry, the contributors of this book have been identified
carefully to make sure that they bring various skills and experiences including biological science,
food science, engineering, marketing, regulatory, legal, financial, sustainability, and manage-
ment. In an era of open innovation, all these skills do not need to be situated in one organization,
Various organizations, commercial businesses, and research institutions can work together to
lead to innovation. In the spirit of open innovation, our book brings together experts from both
industry and academia.
This book puts together various aspects of innovation processes, consumer insights and trends in
developed and developing markets for functional and healthy foods as well as a range of technological
developments in functional foods and ingredients. Also, this book addresses three key drivers of future
xii Preface
innovations in the food industry. These drivers are affordability, sustainability, and ­tightening of gov-
ernment regulation. A total of 34 chapters have been written by renowned experts from around the
world and edited by our team.
Section I gives an overview of innovation in the food industry, focusing on safe, healthy, and
functional foods.
Sections II and III discuss various aspects of the opportunities and scope in different markets for
functional foods. Section II provides characteristics of the markets in different continents (the
United States, Europe, Asia, and around the world) in terms of functional and healthy foods.
Section III provides some insights in consumer perception of functional foods and ingredients.
Sections IV and V discuss various technological aspects associated with innovations in the food
industry. Section IV focuses on innovations in food processing, packaging, and functional ingredi-
ent delivery technology, whereas Section V focuses on various functional and nutritional food
ingredients.
Section VI deals with the connection between innovation and other parts of the business, such as
marketing, sales, regulatory and finance, and analyzes commercial feasibility.
Section VII provides some insights into future trends such as food tourism, nanotechnology,
sustainability, and globalization.
This book is intended for a broad audience associated with food and allied industries, with the
intention of an overview of the contemporary food innovation. This book will be useful for profes-
sionals working in universities and research institutions, food, nutraceutical and pharmaceutical
industries as well as for the students studying food technology and food business. Also, this book
can be a good resource for the entrepreneurs looking for opportunities in food and nutrition
industries.
xiii
Editors
Dilip Ghosh received his PhD in biomedical science from
University of Calcutta, India. Previously, he held positions in
Organon (India) Ltd., a division of Organon International, BV and
AKZO-NOBEL, the Netherlands; HortResearch, New Zealand;
USDA-ARS, HNRCA at Tufts University, Boston, Massachusetts;
The Smart Foods Centre, University of Wollongong, and Neptune
Bio-Innovation Pty Ltd, Sydney, Australia. He has been involved
for a long time in drug development (both synthetic and herbal)
and functional food research and development both in academic
and industry domains. He is a fellow of the American College of
Nutrition and is also on the editorial board of several journals.
Currently, Dr. Ghosh is a director, Nutriconnect, Sydney;
Honorary Ambassador, Global Harmonization Initiative (GHI).
Dr. Ghosh has published more than 70 papers in peer-reviewed journals, numerous articles in food
and nutrition magazines and books. His recent book, Biotechnology in Functional Foods and
Nutraceuticals, was published by CRC Press in 2010. Dr. Ghosh is the review editor of Frontiers
in Nutrigenomics; editorial board member, Panacea E-Newsletter, India; guest columnist of
NutraScope, India; and associate editor and member, Toxicology Mechanisms and Methods, Taylor
 Francis, USA (2006–2007). He can be reached at: dilipghosh@nutriconnect.com.au; dghosh@
optusnet.com.au
Shantanu Das works as product development manager at
Riddet Institute (Centre for Research Excellence in Food and
Nutrition), Massey University, New Zealand. In his current
role, he is responsible for developing new technologies for
commercial application in the food and nutrition industry.
Dr. Das and his team undertake RD projects in various areas
related to functional foods, especially delivery systems of
functional ingredients. His recent achievement is development
of a patented technology for delivering probiotic bacteria at
high concentration through shelf-stable foods, which received
the “Food Industry Innovation Excellence Award 2011” from
theNewZealandInstituteofFoodScientistsandTechnologists.
In his current role, Dr. Das has led a number of projects spon-
sored by domestic and international food industry.
Dr. Das completed his masters in dairy technology from National Dairy Research Institute, India.
He completed his PhD in food technology and post graduate diploma in business management in
New Zealand.
He has worked in the food industry for over 12 years, both in manufacturing and in RD. He
received the “PepsiCo Global Research  Development Award” in 2006 while working for PepsiCo
Asia RD.
xiv Editors
Debasis Bagchi received his PhD in medicinal chemistry in
1982. He is a professor in the Department of Pharmacological and
Pharmaceutical Sciences at the University of Houston, Houston,
Texas. Dr. Bagchi is also the director of Innovation  Clinical
Affairs of Iovate Health Sciences International Inc., Oakville,
Ontario, Canada. Dr. Bagchi is the immediate past president of
the American College of Nutrition, Clearwater, Florida, and also
serves as a distinguished advisor on the Japanese Institute for
Health Food Standards, Tokyo, Japan, and immediate past chair-
man of the Nutraceuticals and Functional Foods Division of the
Institutes of Food Technologists, Chicago, Illinois. Dr. Bagchi
received the Master of American College of Nutrition Award in
October 2010. His research interests include free radicals, human
diseases, carcinogenesis, pathophysiology, mechanistic aspects of
cytoprotection by antioxidants, regulatory pathways in obesity, diabetes, and gene expression.
Dr. Bagchi has 288 papers in peer-reviewed journals, 15 books, and 16 patents. He has delivered
invited lectures in various national and international scientific conferences, organized workshops,
and group discussion sessions. Dr. Bagchi is a Fellow of the American College of Nutrition, member
of the Society of Toxicology, member of the New York Academy of Sciences, Fellow of the Nutrition
Research Academy, and member of the TCE stakeholder Committee of the Wright Patterson Air
Force Base, Ohio. Dr. Bagchi is a member of the Study Section and Peer Review Committee of the
National Institutes of Health, Bethesda, Maryland. Dr. Bagchi is the associate editor of the Journal
of Functional Foods and Journal of the American College of Nutrition, and also serving as editorial
board member of numerous peer-reviewed journals including Antioxidants and Redox Signaling,
Cancer Letters, Toxicology Mechanisms and Methods, and other scientific and medical journals. He
is also a consulting editor of the CRC Press/Taylor  Francis.
Dr. Bagchi has received funding from various institutions and agencies including the U.S. Air
Force Office of Scientific Research, Nebraska State Department of Health, Biomedical Research
Support Grant from National Institutes of Health (NIH), National Cancer Institute (NCI), Health
Future Foundation, The Procter  Gamble Company and Abbott Laboratories.
R.B. Smarta is the founder and ­managing director of Interlink
Marketing Consulting Pvt. Ltd. He obtained an MSc in organic
chemistry (drugs) from the University of Nagpur (1967), MMS
from JBIMS University of Mumbai (1972), and a PhD in man-
agement sciences from the University of East Georgia (1982).
Dr. Smarta is an FRSA (Fellow of the Royal Society of Arts)
conferred by RSA, UK; CMC (Certified Member of Consultants)
by IMCI; corporate trainer; and a teacher. He is a reputed con-
sultant and mentor for corporations in the pharma, nutra, well-
ness, healthcare and lifescience industry, as well as a corporate
trainer. He is faculty in leading management institutions such as
JBIMS (Bajaj Institute of Management Studies), NMIMS (Narsee Monjee Institute of Management
Studies), IIM (Indian Institute of Management), Indore, Pharmacy College, Manipal, and a guide
to PhD students. Dr. Smarta is a board member of HADSA (part of IADSA (International Alliance
Dietary/Food Supplement Associations)) and also an editor of Nutrascope (a HADSA Publication).
He has authored two research books, namely, Strategic Pharmaceutical Marketing and Revitalizing
the Pharmaceutical Business. He has coauthored one book namely (Mega) Market in German
and English.
Dr. Smarta has published articles in journals and news magazines such as Pharma Pulse, Modern
Pharmaceuticals, Pharmabiz, Hindu, Business Today, Outline Today.
xv
Leena Aarikka-Stenroos
Turku School of Economics
University of Turku
Turku, Finland
Philip E. Apong
Innovation  Clinical Affairs
Iovate Health Sciences International Inc.
Oakville, Ontario, Canada
Debasis Bagchi
Department of Pharmacological and
Pharmaceutical Sciences
University of Houston College
of Pharmacy
Houston, Texas
and
Innovation  Clinical Affairs
Iovate Health Sciences International Inc.
Oakville, Ontario, Canada
Virender K. Batish
Dairy Microbiology Division
National Dairy Research Institute
Haryana, India
Abhijit Bhattacharya
OmniActive Health Technologies Ltd.
Maharashtra, India
Alistair Carr
Institute of Food, Nutrition and
Human Health
Massey University
Palmerston North, New Zealand
Dennis Chang
Centre for Complementary
Medicine Research
and
School of Biomedical and Health Sciences
University of Western Sydney
New South Wales, Australia
Srikanta Chatterjee
School of Economics and Finance
Massey University
Palmerston North, New Zealand
Kerrie Close
Goodman Fielder Limited
New South Wales, Australia
Patrick Coppens
International Food and Health Law and
Scientific Affairs
European Advisory Services
Brussels, Belgium
Shantanu Das
Riddet Institute
Massey University
Palmerston North, New Zealand
Jayant Deshpande
OmniActive Health Technologies Ltd.
Maharashtra, India
Mark L. Dreher
Nutrition Science Solutions
Wimberley, Texas
Ruth D’Souza
Interlink Marketing Consultancy Pvt. Ltd.
Maharashtra, India
C.P. Dunne
Combat Feeding Innovative Science
Team
U.S. Army Research, Development, and
Engineering Command
Natick, Massachusetts
Ashling Ellis
Riddet Institute
Massey University
Palmerston North, New Zealand
Contributors
xvi Contributors
Melissa Fry
School of Biomedical Sciences and
Pharmacy
University of Newcastle
New South Wales, Australia
Kata Galic´
Faculty of Food Technology and
Biotechnology
University of Zagreb
Zagreb, Croatia
Manohar L. Garg
School of Biomedical Sciences and
Pharmacy
University of Newcastle
New South Wales, Australia
Dilip Ghosh
Nutriconnect
and
Global Harmonization Initiative
New South Wales, Australia
Sumita Ghosh
School of Built Environment
University of Technology
New South Wales, Australia
Suzanne Grant
Centre for Complementary Medicine Research
University of Western Sydney
New South Wales, Australia
Sunita Grover
Dairy Microbiology Division
National Dairy Research Institute
Haryana, India
Klaus G. Grunert
MAPP Centre for Research on Customer
Relations in the Food Sector
Aarhus University
Aarhus, Denmark
L.M. Hallberg
Combat Feeding Innovative Science Team
U.S. Army Natick Combat
Feeding Program
Natick, Massachusetts
Manki Ho
Cantox Health Sciences International
Mississauga, Ontario, Canada
Tin-Chung Huang
Institute of Health Industry Management
Ching-Kuo Institute of Management
and Health
Taipei, Taiwan
Thom Huppertz
NIZO Food Research BV
Ede, the Netherlands
Girish P. Jakhotiya
Jakhotiya  Associates
Management Consultants
Maharashtra, India
Alex Kocenas
Cantox Health Sciences International
Mississauga, Ontario, Canada
Fanbin Kong
Department of Biological and Agricultural
Engineering
University of California
Davis, California
Ashwani Kumar
Department of Biotechnology
Seth Jai Parkash Mukand Lal Institute
of Engineering and Technology
Haryana, India
Parigi Ramesh Kumar
Central Food Technological Research
Institute
Karnataka, India
Lisa Lähteenmäki
MAPP Centre for Research on Customer
Relations in the Food Sector
Aarhus University
Aarhus, Denmark
Kuan-Huei Lee
School of Tourism
University of Queensland
Queensland, Australia
xviiContributors
Timothy J. Lee
Tourism  Hospitality Management
Ritsumeikan Asia Pacific University
Beppu, Japan
K. Luechapattanaporn
PepsiCo Asia Pacific RD
Bangkok, Thailand
Karen Ly
Cantox Health Sciences International
Mississauga, Ontario, Canada
Kristen Lyons
School of Social Science
University of Queensland
Queensland, Australia
Rekha R. Malia
Biosix Peptides India Pvt. Ltd.
National Incubation Center
Kerala, India
Larry McGirr
Cantox Health Sciences International
Mississauga, Ontario, Canada
Vikas Mittal
Riddet Institute
Massey University
Palmerston North, New Zealand
Arup Nag
Riddet Institute
Massey University
Palmerston North, New Zealand
Srinivas Nammi
School of Biomedical and Health Sciences
University of Western Sydney
New South Wales, Australia
D.B. Anantha Narayana
(retired)
Foods, Home  Personal Care
Unilever Research India
Karnataka, India
M.G. Parameswaran
Draftfcb Ulka Advertising
Maharashtra, India
Hashmukh Patel
Department of Dairy Science
South Dakota State University
Brookings, South Dakota
Lina Paulionis
Cantox Health Sciences International
Mississauga, Ontario, Canada
Melinda Phang
School of Biomedical Sciences and Pharmacy
University of Newcastle
New South Wales, Australia
Ilana Platt
Cantox Health Sciences International
Mississauga, Ontario, Canada
Devastotra Poddar
Riddet Institute
Massey University
Palmerston North, New Zealand
Kalpagam Polasa
Food and Drug Toxicology Research Centre
National Institute of Nutrition
Andhra Pradesh, India
V. Prakash
Research, Innovation, and Development
JSS Technical Instiution Campus
Karnataka, India
Munish Puri
Institute for Technology and Research
Innovation
Deakin University
Victoria, Australia
Rajshri Roy
School of Molecular Bioscience
The University of Sydney
New South Wales, Australia
Birgitta Sandberg
Turku School of Economics
University of Turku
Turku, Finland
Raka Saxena
National Dairy Research Institute
Haryana, India
xviii Contributors
Gyorgy Scrinis
School of Historical and Philosophical Studies
University of Melbourne
Victoria, Australia
B. Sesikeran
Food and Drug Toxicology Research Centre
National Institute of Nutrition
Andhra Pradesh, India
M.L. Shankaranarayana
OmniActive Health Technologies Ltd.
Maharashtra, India
A.K. Singh
National Dairy Research Institute
Haryana, India
Harjinder Singh
Riddet Institute
Massey University
Palmerston North, New Zealand
R. Paul Singh
Department of Biological and
Agricultural Engineering
University of California
Davis, California
R.B. Smarta
Interlink Marketing Consultancy Pvt. Ltd.
Maharashtra, India
A.K. Srivastava
National Dairy Research Institute
Haryana, India
Maya Sugiarto
Riddet Institute
Massey University
Palmerston North, New Zealand
J. Tang
Department of Biological Systems
Engineering
Washington State University
Pullman, Washington
Ashok Vaidya
ICMR Advanced Centre of Reverse
Pharmacology
Kasturba Health Society
Maharashtra, India
Madan Lal Verma
Institute for Technology and Research
Innovation
Deakin University
Victoria, Australia
J. Wang
Department of Biological Systems
Engineering
Washington State University
Pullman, Washington
Y. Wang
Department of Biosystem
Engineering
Auburn University
Auburn, Alabama

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Innovations in healthy and functional foods synopsis.

  • 1.
  • 2.
  • 3.
  • 4. CRC Press is an imprint of the Taylor & Francis Group, an informa business Boca Raton London NewYork DILIP GHOSH • SHANTANU DAS DEBASIS BAGCHI • R.B. SMARTA E d i t e d b y
  • 5. Cover credit:  Aarti Paradkar CRC Press Taylor Francis Group 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487-2742 © 2013 by Taylor Francis Group, LLC CRC Press is an imprint of Taylor Francis Group, an Informa business No claim to original U.S. Government works Version Date: 20120813 International Standard Book Number-13: 978-1-4398-6269-8 (eBook - PDF) This book contains information obtained from authentic and highly regarded sources. Reasonable efforts have been made to publish reliable data and information, but the author and publisher cannot assume responsibility for the validity of all materials or the consequences of their use. The authors and publishers have attempted to trace the copyright holders of all material repro- duced in this publication and apologize to copyright holders if permission to publish in this form has not been obtained. If any copyright material has not been acknowledged please write and let us know so we may rectify in any future reprint. Except as permitted under U.S. Copyright Law, no part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, microfilming, and recording, or in any information storage or retrieval system, without written permission from the publishers. For permission to photocopy or use material electronically from this work, please access www.copyright.com (http://www.copy- right.com/) or contact the Copyright Clearance Center, Inc. (CCC), 222 Rosewood Drive, Danvers, MA 01923, 978-750-8400. CCC is a not-for-profit organization that provides licenses and registration for a variety of users. For organizations that have been granted a photocopy license by the CCC, a separate system of payment has been arranged. Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identifica- tion and explanation without intent to infringe. Visit the Taylor Francis Web site at http://www.taylorandfrancis.com and the CRC Press Web site at http://www.crcpress.com
  • 6. Dedicated to those people who made this world beautiful through their innovations Dilip Ghosh Dedicated to my beloved teacher, Professor Mihir N. Das, DSc, Jadavpur University Debasis Bagchi Dedicated to my beloved family Shantanu Das Dedicated to my beloved mother, who allowed me to explore new avenues in life R.B. Smarta
  • 7.
  • 8. vii Contents Preface...............................................................................................................................................xi Editors............................................................................................................................................. xiii Contributors......................................................................................................................................xv SECTION I  Introduction Chapter 1 Innovation Journey: How to Improve RD Leverage and Speed to Market................3 Dilip Ghosh, Shantanu Das, Debasis Bagchi, and R.B. Smarta Chapter 2 Innovations in Functional Food Industry for Health and Wellness..............................5 Parigi Ramesh Kumar and V. Prakash Chapter 3 Developments and Innovations in Dietary Supplements and Functional Foods.........13 M.L. Shankaranarayana, Jayant Deshpande, and Abhijit Bhattacharya Chapter 4 Innovation in Food Safety and Regulation..................................................................43 Kalpagam Polasa and B. Sesikeran Chapter 5 Creating and Establishing Networks for the Commercialization of Innovations.......57 Leena Aarikka-Stenroos and Birgitta Sandberg SECTION II  Market and Trends Chapter 6 Regulation and Marketing of Nutraceuticals and Functional Foods in Europe: The Broader Impact of Nutrition and Health Claims Regulation.............75 Patrick Coppens Chapter 7 Market and Marketing of Functional Foods and Dietary Supplements in America������������������������������������������������������������������������������������������ 103 Philip E. Apong Chapter 8 Dairy Innovations and Market Growth in India....................................................... 113 Raka Saxena, A.K. Srivastava, and A.K. Singh
  • 9. viii Contents Chapter 9 Changing Global Food Consumption Patterns: An Economic Perspective..............125 Srikanta Chatterjee Chapter 10 Influence of Regulations on the Commercialization and Marketing of Functional Foods and Nutraceuticals in Canada and the United States .................................... 141 Lina Paulionis, Alex Kocenas, Manki Ho, Karen Ly, Larry McGirr, and Ilana Platt SECTION III  Consumer Perspective on Innovation versus Need Chapter 11 Functional Food Trends in India............................................................................... 165 Rekha R. Mallia Chapter 12 New Approaches for Foods and Nutrition for the Bottom of the Pyramid (Gandhi’s Vision)....................................................................................................... 169 Ashok Vaidya Chapter 13 Consumer Reactions to Health Claims on Food Products........................................ 179 Klaus G. Grunert and Lisa Lähteenmäki SECTION IV Technological Development on Healthy and Functional Foods Chapter 14 Effect of Processing on Nutrients in Foods............................................................... 193 Fanbin Kong and R. Paul Singh Chapter 15 Requirements for Innovative Food Packaging.......................................................... 215 Kata Galic´ Chapter 16 Innovation in Iron Fortification: Is the Future in Iron-Binding Milk Proteins?.......249 Ashling Ellis, Vikas Mittal, and Maya Sugiarto Chapter 17 Stabilization of Probiotics for Industrial Application...............................................269 Devastotra Poddar, Arup Nag, Shantanu Das, and Harjinder Singh Chapter 18 Application of Radio Frequency for Military Group Ration Food Package.............305 K. Luechapattanaporn, Y. Wang, J. Wang, J. Tang, L.M. Hallberg, and C.P. Dunne
  • 10. ixContents Chapter 19 Interaction between Food Components and the Innovation Pipeline....................... 319 Alistair Carr Chapter 20 Innovation in Technology Development with Reference to Enzymatic Extraction of Flavonoids........................................................................................... 331 Munish Puri and Madan Lal Verma Chapter 21 Novel Extraction Technology for Antioxidants and Phytochemicals.......................343 Rajshri Roy, Kerrie Close, and Dilip Ghosh SECTION V  Innovation in Functional Food Ingredients Chapter 22 Advances in Milk Protein Ingredients......................................................................363 Thom Huppertz and Hasmukh Patel Chapter 23 Probiotics as Functional Food Ingredients for Augmenting Human Health.............387 Sunita Grover, Ashwani Kumar, A.K. Srivastava, and Virender K. Batish Chapter 24 Omega-3 Polyunsaturated Fatty Acids: Basic and Contemporary Research Issues......................................................................................................... 419 Melinda Phang, Melissa Fry, and Manohar L. Garg Chapter 25 Assessment of Polyphenol-Rich Foods and Beverages on Endothelial (Vascular) Function in Healthy Humans................................................................... 435 Mark L. Dreher Chapter 26 Traditional Understanding, Modern Science, and Usage of Herbal Medicine for Diabetes............................................................................................... 455 Dennis Chang, Srinivas Nammi, and Suzanne Grant SECTION VI  Market to Innovative Products Chapter 27 Drivers and Barriers for Marketing Innovative Functional Food Products..............477 Ruth D’Souza Chapter 28 Marketing, PR, Advertising, and Media for Brand Building of Innovative Foods and Nutritional Products.................................................................................485 M.G. Parameswaran
  • 11. x Contents Chapter 29 Financial Implications of Innovations.......................................................................495 Girish P. Jakhotiya Chapter 30 Market-Focused Innovation in Food and Nutrition...................................................509 R.B. Smarta SECTION VII  Future Trends Chapter 31 Innovation in Food Tourism and Product Distribution.............................................523 Timothy J. Lee, Tin-Chung Huang, and Kuan-Huei Lee Chapter 32 Regulations and Innovations Interphase................................................................... 531 D.B. Anantha Narayana Chapter 33 Nano-Functional Foods: Nanotechnology, Nutritional Engineering, and Nutritionally Reductive Food Marketing...........................................................547 Gyorgy Scrinis and Kristen Lyons Chapter 34 Sustainability of Local Food Production: A Review on Energy and Environmental Perspectives...................................................................................... 555 Sumita Ghosh Index .............................................................................................................................................. 581
  • 12. xi Preface Our new book Innovation in Healthy and Functional Foods endeavors to integrate two key contem- porary concepts “innovation” and “functional and healthy foods,” the major thrust in the world of food, nutrition, and nutraceuticals. This book includes topics that have been researched in academia but have the potential to be applied in the food industry. The question arises in mind as to which step in the innovation process would be ideal for academia–industry collaboration. The collaboration may take place at any step in the innovation process, that is, ideation, feasibility, development, commercialization, and launch. However, we think the most ideal point is at stage zero, that is, even before a particular project has been conceived. At this stage, as the industry scans the consumers’ needs and desires it can also scan the new technologies, solutions, and capabilities available within academia. It is always hard to decide when to adopt a technology from academic research into industrial development. Though there is no strict rule yet it can be said that an organization with strong RD may adopt a technology in its initial stage and develop it further. On the other hand for a market-driven organization it is more convenient to adopt a mature technology. All these innovation concepts, though based on stud- ies in multiple industries, can be successfully applied to the food industry. The focus on food science and technology has transformed over centuries. In the past, the focus of food science and technology was food security. This resulted in rapid improvement in agricul- tural production techniques. Then the focus shifted to food safety and as a result a range of food preservation techniques were developed. Once the food was proven safe, the taste, flavor, texture, appearance, and other sensorial attributes of the food became the priority of the food industry to satisfy consumer acceptance. After the development of safe and tasty foods, the focus of food sci- ence and technology shifted toward healthy and functional foods. Functional food is defined as food capable of providing health benefits beyond basic nutrition. Today, consumers desire foods that are capable of playing not only a “health-promoting” but also a “disease-preventing” role, over and above their routine function of supporting growth and maintenance. A functional food may be of four types: (1) a natural food in which one of the components has been naturally present at relatively high concentrations; (2) a food to which a component has been added to provide benefits; (3) a food from which a component has been removed so that the food has less adverse health effects; and (4) a food in which the absorption of one or more components has been increased to prove a beneficial effect. This book focuses mainly on the type 2 functional food and conducts a fairly detail exploration into the functional ingredients (e.g., omega-3, probiotics, protein, iron, etc.) and their delivery techniques into consumer foods. Innovation in functional and healthy foods can be carried out successfully only by a cross- functional team as expertise in various subjects is required to be integrated. To be able to deliver the innovation process to the food industry, the contributors of this book have been identified carefully to make sure that they bring various skills and experiences including biological science, food science, engineering, marketing, regulatory, legal, financial, sustainability, and manage- ment. In an era of open innovation, all these skills do not need to be situated in one organization, Various organizations, commercial businesses, and research institutions can work together to lead to innovation. In the spirit of open innovation, our book brings together experts from both industry and academia. This book puts together various aspects of innovation processes, consumer insights and trends in developed and developing markets for functional and healthy foods as well as a range of technological developments in functional foods and ingredients. Also, this book addresses three key drivers of future
  • 13. xii Preface innovations in the food industry. These drivers are affordability, sustainability, and ­tightening of gov- ernment regulation. A total of 34 chapters have been written by renowned experts from around the world and edited by our team. Section I gives an overview of innovation in the food industry, focusing on safe, healthy, and functional foods. Sections II and III discuss various aspects of the opportunities and scope in different markets for functional foods. Section II provides characteristics of the markets in different continents (the United States, Europe, Asia, and around the world) in terms of functional and healthy foods. Section III provides some insights in consumer perception of functional foods and ingredients. Sections IV and V discuss various technological aspects associated with innovations in the food industry. Section IV focuses on innovations in food processing, packaging, and functional ingredi- ent delivery technology, whereas Section V focuses on various functional and nutritional food ingredients. Section VI deals with the connection between innovation and other parts of the business, such as marketing, sales, regulatory and finance, and analyzes commercial feasibility. Section VII provides some insights into future trends such as food tourism, nanotechnology, sustainability, and globalization. This book is intended for a broad audience associated with food and allied industries, with the intention of an overview of the contemporary food innovation. This book will be useful for profes- sionals working in universities and research institutions, food, nutraceutical and pharmaceutical industries as well as for the students studying food technology and food business. Also, this book can be a good resource for the entrepreneurs looking for opportunities in food and nutrition industries.
  • 14. xiii Editors Dilip Ghosh received his PhD in biomedical science from University of Calcutta, India. Previously, he held positions in Organon (India) Ltd., a division of Organon International, BV and AKZO-NOBEL, the Netherlands; HortResearch, New Zealand; USDA-ARS, HNRCA at Tufts University, Boston, Massachusetts; The Smart Foods Centre, University of Wollongong, and Neptune Bio-Innovation Pty Ltd, Sydney, Australia. He has been involved for a long time in drug development (both synthetic and herbal) and functional food research and development both in academic and industry domains. He is a fellow of the American College of Nutrition and is also on the editorial board of several journals. Currently, Dr. Ghosh is a director, Nutriconnect, Sydney; Honorary Ambassador, Global Harmonization Initiative (GHI). Dr. Ghosh has published more than 70 papers in peer-reviewed journals, numerous articles in food and nutrition magazines and books. His recent book, Biotechnology in Functional Foods and Nutraceuticals, was published by CRC Press in 2010. Dr. Ghosh is the review editor of Frontiers in Nutrigenomics; editorial board member, Panacea E-Newsletter, India; guest columnist of NutraScope, India; and associate editor and member, Toxicology Mechanisms and Methods, Taylor Francis, USA (2006–2007). He can be reached at: dilipghosh@nutriconnect.com.au; dghosh@ optusnet.com.au Shantanu Das works as product development manager at Riddet Institute (Centre for Research Excellence in Food and Nutrition), Massey University, New Zealand. In his current role, he is responsible for developing new technologies for commercial application in the food and nutrition industry. Dr. Das and his team undertake RD projects in various areas related to functional foods, especially delivery systems of functional ingredients. His recent achievement is development of a patented technology for delivering probiotic bacteria at high concentration through shelf-stable foods, which received the “Food Industry Innovation Excellence Award 2011” from theNewZealandInstituteofFoodScientistsandTechnologists. In his current role, Dr. Das has led a number of projects spon- sored by domestic and international food industry. Dr. Das completed his masters in dairy technology from National Dairy Research Institute, India. He completed his PhD in food technology and post graduate diploma in business management in New Zealand. He has worked in the food industry for over 12 years, both in manufacturing and in RD. He received the “PepsiCo Global Research Development Award” in 2006 while working for PepsiCo Asia RD.
  • 15. xiv Editors Debasis Bagchi received his PhD in medicinal chemistry in 1982. He is a professor in the Department of Pharmacological and Pharmaceutical Sciences at the University of Houston, Houston, Texas. Dr. Bagchi is also the director of Innovation Clinical Affairs of Iovate Health Sciences International Inc., Oakville, Ontario, Canada. Dr. Bagchi is the immediate past president of the American College of Nutrition, Clearwater, Florida, and also serves as a distinguished advisor on the Japanese Institute for Health Food Standards, Tokyo, Japan, and immediate past chair- man of the Nutraceuticals and Functional Foods Division of the Institutes of Food Technologists, Chicago, Illinois. Dr. Bagchi received the Master of American College of Nutrition Award in October 2010. His research interests include free radicals, human diseases, carcinogenesis, pathophysiology, mechanistic aspects of cytoprotection by antioxidants, regulatory pathways in obesity, diabetes, and gene expression. Dr. Bagchi has 288 papers in peer-reviewed journals, 15 books, and 16 patents. He has delivered invited lectures in various national and international scientific conferences, organized workshops, and group discussion sessions. Dr. Bagchi is a Fellow of the American College of Nutrition, member of the Society of Toxicology, member of the New York Academy of Sciences, Fellow of the Nutrition Research Academy, and member of the TCE stakeholder Committee of the Wright Patterson Air Force Base, Ohio. Dr. Bagchi is a member of the Study Section and Peer Review Committee of the National Institutes of Health, Bethesda, Maryland. Dr. Bagchi is the associate editor of the Journal of Functional Foods and Journal of the American College of Nutrition, and also serving as editorial board member of numerous peer-reviewed journals including Antioxidants and Redox Signaling, Cancer Letters, Toxicology Mechanisms and Methods, and other scientific and medical journals. He is also a consulting editor of the CRC Press/Taylor Francis. Dr. Bagchi has received funding from various institutions and agencies including the U.S. Air Force Office of Scientific Research, Nebraska State Department of Health, Biomedical Research Support Grant from National Institutes of Health (NIH), National Cancer Institute (NCI), Health Future Foundation, The Procter Gamble Company and Abbott Laboratories. R.B. Smarta is the founder and ­managing director of Interlink Marketing Consulting Pvt. Ltd. He obtained an MSc in organic chemistry (drugs) from the University of Nagpur (1967), MMS from JBIMS University of Mumbai (1972), and a PhD in man- agement sciences from the University of East Georgia (1982). Dr. Smarta is an FRSA (Fellow of the Royal Society of Arts) conferred by RSA, UK; CMC (Certified Member of Consultants) by IMCI; corporate trainer; and a teacher. He is a reputed con- sultant and mentor for corporations in the pharma, nutra, well- ness, healthcare and lifescience industry, as well as a corporate trainer. He is faculty in leading management institutions such as JBIMS (Bajaj Institute of Management Studies), NMIMS (Narsee Monjee Institute of Management Studies), IIM (Indian Institute of Management), Indore, Pharmacy College, Manipal, and a guide to PhD students. Dr. Smarta is a board member of HADSA (part of IADSA (International Alliance Dietary/Food Supplement Associations)) and also an editor of Nutrascope (a HADSA Publication). He has authored two research books, namely, Strategic Pharmaceutical Marketing and Revitalizing the Pharmaceutical Business. He has coauthored one book namely (Mega) Market in German and English. Dr. Smarta has published articles in journals and news magazines such as Pharma Pulse, Modern Pharmaceuticals, Pharmabiz, Hindu, Business Today, Outline Today.
  • 16. xv Leena Aarikka-Stenroos Turku School of Economics University of Turku Turku, Finland Philip E. Apong Innovation Clinical Affairs Iovate Health Sciences International Inc. Oakville, Ontario, Canada Debasis Bagchi Department of Pharmacological and Pharmaceutical Sciences University of Houston College of Pharmacy Houston, Texas and Innovation Clinical Affairs Iovate Health Sciences International Inc. Oakville, Ontario, Canada Virender K. Batish Dairy Microbiology Division National Dairy Research Institute Haryana, India Abhijit Bhattacharya OmniActive Health Technologies Ltd. Maharashtra, India Alistair Carr Institute of Food, Nutrition and Human Health Massey University Palmerston North, New Zealand Dennis Chang Centre for Complementary Medicine Research and School of Biomedical and Health Sciences University of Western Sydney New South Wales, Australia Srikanta Chatterjee School of Economics and Finance Massey University Palmerston North, New Zealand Kerrie Close Goodman Fielder Limited New South Wales, Australia Patrick Coppens International Food and Health Law and Scientific Affairs European Advisory Services Brussels, Belgium Shantanu Das Riddet Institute Massey University Palmerston North, New Zealand Jayant Deshpande OmniActive Health Technologies Ltd. Maharashtra, India Mark L. Dreher Nutrition Science Solutions Wimberley, Texas Ruth D’Souza Interlink Marketing Consultancy Pvt. Ltd. Maharashtra, India C.P. Dunne Combat Feeding Innovative Science Team U.S. Army Research, Development, and Engineering Command Natick, Massachusetts Ashling Ellis Riddet Institute Massey University Palmerston North, New Zealand Contributors
  • 17. xvi Contributors Melissa Fry School of Biomedical Sciences and Pharmacy University of Newcastle New South Wales, Australia Kata Galic´ Faculty of Food Technology and Biotechnology University of Zagreb Zagreb, Croatia Manohar L. Garg School of Biomedical Sciences and Pharmacy University of Newcastle New South Wales, Australia Dilip Ghosh Nutriconnect and Global Harmonization Initiative New South Wales, Australia Sumita Ghosh School of Built Environment University of Technology New South Wales, Australia Suzanne Grant Centre for Complementary Medicine Research University of Western Sydney New South Wales, Australia Sunita Grover Dairy Microbiology Division National Dairy Research Institute Haryana, India Klaus G. Grunert MAPP Centre for Research on Customer Relations in the Food Sector Aarhus University Aarhus, Denmark L.M. Hallberg Combat Feeding Innovative Science Team U.S. Army Natick Combat Feeding Program Natick, Massachusetts Manki Ho Cantox Health Sciences International Mississauga, Ontario, Canada Tin-Chung Huang Institute of Health Industry Management Ching-Kuo Institute of Management and Health Taipei, Taiwan Thom Huppertz NIZO Food Research BV Ede, the Netherlands Girish P. Jakhotiya Jakhotiya Associates Management Consultants Maharashtra, India Alex Kocenas Cantox Health Sciences International Mississauga, Ontario, Canada Fanbin Kong Department of Biological and Agricultural Engineering University of California Davis, California Ashwani Kumar Department of Biotechnology Seth Jai Parkash Mukand Lal Institute of Engineering and Technology Haryana, India Parigi Ramesh Kumar Central Food Technological Research Institute Karnataka, India Lisa Lähteenmäki MAPP Centre for Research on Customer Relations in the Food Sector Aarhus University Aarhus, Denmark Kuan-Huei Lee School of Tourism University of Queensland Queensland, Australia
  • 18. xviiContributors Timothy J. Lee Tourism Hospitality Management Ritsumeikan Asia Pacific University Beppu, Japan K. Luechapattanaporn PepsiCo Asia Pacific RD Bangkok, Thailand Karen Ly Cantox Health Sciences International Mississauga, Ontario, Canada Kristen Lyons School of Social Science University of Queensland Queensland, Australia Rekha R. Malia Biosix Peptides India Pvt. Ltd. National Incubation Center Kerala, India Larry McGirr Cantox Health Sciences International Mississauga, Ontario, Canada Vikas Mittal Riddet Institute Massey University Palmerston North, New Zealand Arup Nag Riddet Institute Massey University Palmerston North, New Zealand Srinivas Nammi School of Biomedical and Health Sciences University of Western Sydney New South Wales, Australia D.B. Anantha Narayana (retired) Foods, Home Personal Care Unilever Research India Karnataka, India M.G. Parameswaran Draftfcb Ulka Advertising Maharashtra, India Hashmukh Patel Department of Dairy Science South Dakota State University Brookings, South Dakota Lina Paulionis Cantox Health Sciences International Mississauga, Ontario, Canada Melinda Phang School of Biomedical Sciences and Pharmacy University of Newcastle New South Wales, Australia Ilana Platt Cantox Health Sciences International Mississauga, Ontario, Canada Devastotra Poddar Riddet Institute Massey University Palmerston North, New Zealand Kalpagam Polasa Food and Drug Toxicology Research Centre National Institute of Nutrition Andhra Pradesh, India V. Prakash Research, Innovation, and Development JSS Technical Instiution Campus Karnataka, India Munish Puri Institute for Technology and Research Innovation Deakin University Victoria, Australia Rajshri Roy School of Molecular Bioscience The University of Sydney New South Wales, Australia Birgitta Sandberg Turku School of Economics University of Turku Turku, Finland Raka Saxena National Dairy Research Institute Haryana, India
  • 19. xviii Contributors Gyorgy Scrinis School of Historical and Philosophical Studies University of Melbourne Victoria, Australia B. Sesikeran Food and Drug Toxicology Research Centre National Institute of Nutrition Andhra Pradesh, India M.L. Shankaranarayana OmniActive Health Technologies Ltd. Maharashtra, India A.K. Singh National Dairy Research Institute Haryana, India Harjinder Singh Riddet Institute Massey University Palmerston North, New Zealand R. Paul Singh Department of Biological and Agricultural Engineering University of California Davis, California R.B. Smarta Interlink Marketing Consultancy Pvt. Ltd. Maharashtra, India A.K. Srivastava National Dairy Research Institute Haryana, India Maya Sugiarto Riddet Institute Massey University Palmerston North, New Zealand J. Tang Department of Biological Systems Engineering Washington State University Pullman, Washington Ashok Vaidya ICMR Advanced Centre of Reverse Pharmacology Kasturba Health Society Maharashtra, India Madan Lal Verma Institute for Technology and Research Innovation Deakin University Victoria, Australia J. Wang Department of Biological Systems Engineering Washington State University Pullman, Washington Y. Wang Department of Biosystem Engineering Auburn University Auburn, Alabama