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International Wheat Yield
Partnership
Research to Deliver Wheat for the Future
• Richard Flavell, Member of Science and Impact Executive Board
• Hans Braun, CIMMYT
• Mike Robinson, Syngenta Foundation for Sustainable Agriculture
• Steve Visscher, BBSRC
• Nora Lapitan, USAID
www.iwyp.org
Goal
To increase wheat yield potential by up to
50% in 20 years:
– Exploit the best relevant science base worldwide
– Incorporate and evaluate in elite germplasm
– Transfer germplasm to leading relevant breeding programs
around the world, public and private
• To be inspired and managed by an independent
management team and structure, linked with the private
sector and developed with state of the art technologies
• To be focused on delivery with a high degree of urgency
Why now?
• Demands for wheat are increasing
• Gains in breeding programs around the world have
slowed to dangerous levels
• New interest from private sector and governments
• Many helpful initiatives around the world in yield
protection e.g. in disease control but fewer in yield
potential
• New technologies and scientific discoveries offer new
possibilities
Why now?
• Unprecedented progress in underpinning science in
discovery and breeding methods e.g. genome
sequencing, marker assisted breeding and genomic
selection in many crops
• Many relevant discoveries are emerging that could
be built into wheat e.g. photosynthesis
• Breeding, dissemination, re-breeding into varieties
and evaluation in many environments takes time
• A Technical Committee met to address how to
increase substantially the genetic yield
potential of wheat and produced a report
• Six themes were recommended around the
concept of creating plants that act as better
photosynthesis machines
• These were similar to what had been selected
previously by CIMMYT and colleagues as part
of the Wheat Yield Consortium
Carbon Fixation and Grain Yields
Canopy and Biomass Building Senescence and
grain filling
Optimize
flowering time
Optimize carbon fixation and
canopy growth/architecture
Airborne Remote Sensing Platform for High
Throughput Phenotyping
Rapid screening for large trials:
AB1100 tethered
helium filled blimp
Astec Falcon 8, remote controlled UAV
Airborne measurements well associated
with ground based data
r=0.84
0.50
0.60
0.70
0.80
0.50 0.60 0.70 0.80
NDVIGROUND
MSAVI BLIMP
MSAVI BLIMP VS NDVI
Ground Drought_1
r=-0.86
0.50
0.60
0.70
0.80
0.10 0.20 0.30 0.40
NDVIGROUND
NCPI BLIMP
NCPI BLIMP VS NDVI Ground
Drought_1
r=0.91
0.60
0.65
0.70
0.75
0.20 0.25 0.30 0.35
NDVIGROUND
NDVI BLIMP
NDVI BLIMP VS NDVI Ground
Irrigation_1
r=0.91
0.60
0.65
0.70
0.75
0.56 0.61 0.66
NDVIGROUND
PSND BLIMP
PSND BLIMP VS NDVI Ground
Irrigation_1
Opportunities Around the World
• Screening new germplasm for higher biomass
• Screening wheat relatives for more efficient
photosynthesis at multiple temperatures
• Selecting variant architecture, e.g. awns with high
photosynthetic outputs
• Looking for variant Rubisco enzymes in wheat relatives
• Selecting better Rubisco activase genes
• Changing Rubisco genes
• Improving the efficiency of regenerating Rubisco
substrate
40 20 0 0 20
-40 -20 0 20
Spike
Lamina
Sheath
True
stem
WHEAT DESIGN: Available genetic variation in
DM partitioning 7 days after anthesis (%)
Bars represent genetic range
Structural
.. fixed
Soluble
.. redistributable
9 CIMCOG cultivars raised beds, 2011-12 and 2012-13.
Design targets for HI
↓ Struct. T. stem & L. Shth
↑ Soluble T. stem
C. Rivera, E. Trujillo, M Reynolds, R Sylvester-Bradley, G. Molero, J Foulkes.
.
Variation in Harvest Index and Yield
From Foulkes et al, Nottingham University
To Drive Traits Towards the Market
• Define genetic basis of each trait using markers
• Transfer trait(s) to elite germplasm using markers
• Stack traits to create super engine, optimizing
phenology and harvest index
• Evaluate germplasm in field settings
• Pre-breed and select
• Release to worldwide breeding programs
Six Project Areas
• A and B: Improving light capture and conversion into more
biomass during growing season using:
– wheat and wheat related genetics
– proven transgenes
• C: Maximizing grain yields from increased biomass by
maintaining or improving harvest index
• D: Building elite, improved lines for transfer to other
breeding programs
• E: Taking advantage of discoveries from other initiatives
• F: Breakthrough technologies for wheat breeding
Integrated Technologies for a
World Class Program
To aid management of traits in breeding
programs the Hub needs to have, or be linked
to, up-to date very high-throughput marker
analysis platforms
– Up to date markers from worldwide programs
– Efficient phenotyping platforms
– Leading computational biology and trait breeding
systems
IWYP Breeding and Research Hub
CIMMYT-Mexico
Access governed by SIEB
State-of-the-Art High Throughput Field Phenotyping Platform for Trait Validation
Trait Introgression Platform (via the Mexico-CIMMYT Shuttle)
Hosting and Support Services for IWYP Partner Experiments
Data Management/Sharing and Technical Cooperation
Bio-Secure Transgenic Testing Platform
Integration with WHEAT IWIN and National Programs
Genotyping Platforms / Marker Library
Critical Mass of Physiologists, Geneticists, Breeders, and Support Staff
How will IWYP interact?
INTERNATIONAL WHEAT
YIELD PARTNERSHIP
Private Sector National Breeding
Programmes
International nursery
systems
FARMERS
RELEVANT NATIONAL
PROGRAMES
NARS
Universities
WISP
Breedwheat
TriticeaeCAP
CTAG
Others …
RELEVANT
INTERNATIONAL
ACTIVITIES
Wheat Initiative
C4 Rice
WHEAT CRP
RIPE
BGRI
Others …
Private Sector Engagement
• Aim: to partner in guiding, assessing and
assisting the research program and the broad
deployment of outputs of the IWYP
• Contributions: advise the Executive Board in priority setting,
sharing of germplasm, technology services, product
development
• Benefits: early insights, access to grants process, networking
• Membership fund: will cover the overheads of the PPP
• Intellectual property: wheat material under development
produced by the IWYP would be available for use as parental
breeding material subject to an appropriate material transfer
agreement
Public Private Partnership
• Bayer Cropscience
• Caussade-Semences
• Dow Agrosciences
• DuPont Pioneer
• InterGrain
• KWS
• Lemaire Deffontaines
• Limagrain
• Momont
• Nordsaat
• Saaten Union
Recherches
• SECOBRA Recherches
• Syngenta
A number of companies have expressed interest, some
have already applied for membership:
IWYP Breeding &
Research Hub
Program Director
Secretariat
Industrial
Stakeholder
Group
Other
National /
International
Programs
Data
Management
IWYP Aligned
Programs
Organisational Structure
International Wheat Yield Partnership
Science & Impact Executive Board
International Wheat Yield Partnership
Science Leadership Committee
IWYP
Competitively
Funded
Projects
Program Plans
Year 1
• Launch IWYP
• Develop PPP
• Appoint Director
• Establish SIEB
• Establish Hub
• Establish SLC
• Launch 1st
Competitive call
Year 2
• Launch 2nd Call
• Launch Program F
Years 3 - 5
• Outputs
• Outcomes
• Dissemination
Engage with other Programs and Develop New Partnerships
Progress and Future Plans
Funding is in place to:
• Appoint the IWYP Program Director
• Establish IWYP Breeding Hub at CIMMYT
• Launch Initial call(s) for proposals
• Establish Science and Impact Executive Board - funders,
leading scientists from public and private sectors
• Establish Scientific Leadership Committee
• Flexible mechanisms to allow funding partners to
contribute resources
• Seek additional partners from all sectors
• We are receptive to ideas and welcome feedback
Benefits to Developed and
Developing Countries and their research
• Development of a strong global wheat public-
private research community that share resources,
capabilities, data and ideas to improve wheat
yield potential
• Transforming the way wheat researchers work,
enabling the fast generation of elite lines that are
readily accessible to breeders
• Training of a new generation of breeders across
the world
• New discoveries leading to new projects funded
from other sources, leveraging initial investments
Increase in Cereal Production to Feed
9 Billion People by 2050
Tester and Langridge. 2010. Science 327:818
60% increase
in wheat
production to
meet food
demands by
2050.
Benefits to Developed and
Developing Countries
Significantly increasing wheat yield potential
could generate up to 160 million tons of wheat
per year – or an estimated $50-100 billion in
additional income annually.
“Take it to the farmers.”
Norman Borlaug
IWYPhas beendevelopedin
partnership
Q and A and Discussion
Thank you for listening:
• Q & A
• Discussion
• Feedback
www.iwyp.org
Program Development
IWYP will support research by a range of mechanisms:
• Competitive funding calls to attract world class science
• A breeding and research hub supported by technical
platforms based at CIMMYT
• Alignment of existing, directly relevant, research in other
programs
• Flexible mechanisms to allow funding partners to
contribute resources
• Sharing with the private sector
IWYP will also:
• Facilitate the partnership with the private sector
• Work with other International Programs
• Manage IP and licensing
Saharah Moon to present
Anticipated Outcomes
Increase yield potential by 50%:
• Stronger and elevated state-of-the-art breeding programs at
CIMMYT
• Breeding systems and new phenotypic assays for stacking traits
• First lines reaching national programs from more productive
breeding programs
• Knowledge of genetic variation traits for carbon capture
through to biomass and grain yields
• IWYP training programs generate a greater cadre of trained
scientists and breeders
• Stronger industrial sector for delivering higher yielding varieties

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International Wheat Yield Partnership

  • 1. International Wheat Yield Partnership Research to Deliver Wheat for the Future • Richard Flavell, Member of Science and Impact Executive Board • Hans Braun, CIMMYT • Mike Robinson, Syngenta Foundation for Sustainable Agriculture • Steve Visscher, BBSRC • Nora Lapitan, USAID www.iwyp.org
  • 2. Goal To increase wheat yield potential by up to 50% in 20 years: – Exploit the best relevant science base worldwide – Incorporate and evaluate in elite germplasm – Transfer germplasm to leading relevant breeding programs around the world, public and private • To be inspired and managed by an independent management team and structure, linked with the private sector and developed with state of the art technologies • To be focused on delivery with a high degree of urgency
  • 3. Why now? • Demands for wheat are increasing • Gains in breeding programs around the world have slowed to dangerous levels • New interest from private sector and governments • Many helpful initiatives around the world in yield protection e.g. in disease control but fewer in yield potential • New technologies and scientific discoveries offer new possibilities
  • 4. Why now? • Unprecedented progress in underpinning science in discovery and breeding methods e.g. genome sequencing, marker assisted breeding and genomic selection in many crops • Many relevant discoveries are emerging that could be built into wheat e.g. photosynthesis • Breeding, dissemination, re-breeding into varieties and evaluation in many environments takes time
  • 5. • A Technical Committee met to address how to increase substantially the genetic yield potential of wheat and produced a report • Six themes were recommended around the concept of creating plants that act as better photosynthesis machines • These were similar to what had been selected previously by CIMMYT and colleagues as part of the Wheat Yield Consortium
  • 6. Carbon Fixation and Grain Yields Canopy and Biomass Building Senescence and grain filling Optimize flowering time Optimize carbon fixation and canopy growth/architecture
  • 7. Airborne Remote Sensing Platform for High Throughput Phenotyping Rapid screening for large trials: AB1100 tethered helium filled blimp Astec Falcon 8, remote controlled UAV
  • 8. Airborne measurements well associated with ground based data r=0.84 0.50 0.60 0.70 0.80 0.50 0.60 0.70 0.80 NDVIGROUND MSAVI BLIMP MSAVI BLIMP VS NDVI Ground Drought_1 r=-0.86 0.50 0.60 0.70 0.80 0.10 0.20 0.30 0.40 NDVIGROUND NCPI BLIMP NCPI BLIMP VS NDVI Ground Drought_1 r=0.91 0.60 0.65 0.70 0.75 0.20 0.25 0.30 0.35 NDVIGROUND NDVI BLIMP NDVI BLIMP VS NDVI Ground Irrigation_1 r=0.91 0.60 0.65 0.70 0.75 0.56 0.61 0.66 NDVIGROUND PSND BLIMP PSND BLIMP VS NDVI Ground Irrigation_1
  • 9. Opportunities Around the World • Screening new germplasm for higher biomass • Screening wheat relatives for more efficient photosynthesis at multiple temperatures • Selecting variant architecture, e.g. awns with high photosynthetic outputs • Looking for variant Rubisco enzymes in wheat relatives • Selecting better Rubisco activase genes • Changing Rubisco genes • Improving the efficiency of regenerating Rubisco substrate
  • 10. 40 20 0 0 20 -40 -20 0 20 Spike Lamina Sheath True stem WHEAT DESIGN: Available genetic variation in DM partitioning 7 days after anthesis (%) Bars represent genetic range Structural .. fixed Soluble .. redistributable 9 CIMCOG cultivars raised beds, 2011-12 and 2012-13. Design targets for HI ↓ Struct. T. stem & L. Shth ↑ Soluble T. stem C. Rivera, E. Trujillo, M Reynolds, R Sylvester-Bradley, G. Molero, J Foulkes. .
  • 11. Variation in Harvest Index and Yield From Foulkes et al, Nottingham University
  • 12. To Drive Traits Towards the Market • Define genetic basis of each trait using markers • Transfer trait(s) to elite germplasm using markers • Stack traits to create super engine, optimizing phenology and harvest index • Evaluate germplasm in field settings • Pre-breed and select • Release to worldwide breeding programs
  • 13. Six Project Areas • A and B: Improving light capture and conversion into more biomass during growing season using: – wheat and wheat related genetics – proven transgenes • C: Maximizing grain yields from increased biomass by maintaining or improving harvest index • D: Building elite, improved lines for transfer to other breeding programs • E: Taking advantage of discoveries from other initiatives • F: Breakthrough technologies for wheat breeding
  • 14. Integrated Technologies for a World Class Program To aid management of traits in breeding programs the Hub needs to have, or be linked to, up-to date very high-throughput marker analysis platforms – Up to date markers from worldwide programs – Efficient phenotyping platforms – Leading computational biology and trait breeding systems
  • 15. IWYP Breeding and Research Hub CIMMYT-Mexico Access governed by SIEB State-of-the-Art High Throughput Field Phenotyping Platform for Trait Validation Trait Introgression Platform (via the Mexico-CIMMYT Shuttle) Hosting and Support Services for IWYP Partner Experiments Data Management/Sharing and Technical Cooperation Bio-Secure Transgenic Testing Platform Integration with WHEAT IWIN and National Programs Genotyping Platforms / Marker Library Critical Mass of Physiologists, Geneticists, Breeders, and Support Staff
  • 16. How will IWYP interact? INTERNATIONAL WHEAT YIELD PARTNERSHIP Private Sector National Breeding Programmes International nursery systems FARMERS RELEVANT NATIONAL PROGRAMES NARS Universities WISP Breedwheat TriticeaeCAP CTAG Others … RELEVANT INTERNATIONAL ACTIVITIES Wheat Initiative C4 Rice WHEAT CRP RIPE BGRI Others …
  • 17. Private Sector Engagement • Aim: to partner in guiding, assessing and assisting the research program and the broad deployment of outputs of the IWYP • Contributions: advise the Executive Board in priority setting, sharing of germplasm, technology services, product development • Benefits: early insights, access to grants process, networking • Membership fund: will cover the overheads of the PPP • Intellectual property: wheat material under development produced by the IWYP would be available for use as parental breeding material subject to an appropriate material transfer agreement
  • 18. Public Private Partnership • Bayer Cropscience • Caussade-Semences • Dow Agrosciences • DuPont Pioneer • InterGrain • KWS • Lemaire Deffontaines • Limagrain • Momont • Nordsaat • Saaten Union Recherches • SECOBRA Recherches • Syngenta A number of companies have expressed interest, some have already applied for membership:
  • 19. IWYP Breeding & Research Hub Program Director Secretariat Industrial Stakeholder Group Other National / International Programs Data Management IWYP Aligned Programs Organisational Structure International Wheat Yield Partnership Science & Impact Executive Board International Wheat Yield Partnership Science Leadership Committee IWYP Competitively Funded Projects
  • 20. Program Plans Year 1 • Launch IWYP • Develop PPP • Appoint Director • Establish SIEB • Establish Hub • Establish SLC • Launch 1st Competitive call Year 2 • Launch 2nd Call • Launch Program F Years 3 - 5 • Outputs • Outcomes • Dissemination Engage with other Programs and Develop New Partnerships
  • 21. Progress and Future Plans Funding is in place to: • Appoint the IWYP Program Director • Establish IWYP Breeding Hub at CIMMYT • Launch Initial call(s) for proposals • Establish Science and Impact Executive Board - funders, leading scientists from public and private sectors • Establish Scientific Leadership Committee • Flexible mechanisms to allow funding partners to contribute resources • Seek additional partners from all sectors • We are receptive to ideas and welcome feedback
  • 22. Benefits to Developed and Developing Countries and their research • Development of a strong global wheat public- private research community that share resources, capabilities, data and ideas to improve wheat yield potential • Transforming the way wheat researchers work, enabling the fast generation of elite lines that are readily accessible to breeders • Training of a new generation of breeders across the world • New discoveries leading to new projects funded from other sources, leveraging initial investments
  • 23. Increase in Cereal Production to Feed 9 Billion People by 2050 Tester and Langridge. 2010. Science 327:818 60% increase in wheat production to meet food demands by 2050.
  • 24. Benefits to Developed and Developing Countries Significantly increasing wheat yield potential could generate up to 160 million tons of wheat per year – or an estimated $50-100 billion in additional income annually. “Take it to the farmers.” Norman Borlaug
  • 26. Q and A and Discussion Thank you for listening: • Q & A • Discussion • Feedback www.iwyp.org
  • 27.
  • 28. Program Development IWYP will support research by a range of mechanisms: • Competitive funding calls to attract world class science • A breeding and research hub supported by technical platforms based at CIMMYT • Alignment of existing, directly relevant, research in other programs • Flexible mechanisms to allow funding partners to contribute resources • Sharing with the private sector IWYP will also: • Facilitate the partnership with the private sector • Work with other International Programs • Manage IP and licensing Saharah Moon to present
  • 29. Anticipated Outcomes Increase yield potential by 50%: • Stronger and elevated state-of-the-art breeding programs at CIMMYT • Breeding systems and new phenotypic assays for stacking traits • First lines reaching national programs from more productive breeding programs • Knowledge of genetic variation traits for carbon capture through to biomass and grain yields • IWYP training programs generate a greater cadre of trained scientists and breeders • Stronger industrial sector for delivering higher yielding varieties