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Estimated Impact of HIV Prevention Budget Cuts
     for Selected Jurisdictions in California



            Feng Lin, PhD; Arielle Lasry, PhD;
        Annette Ladan, MS; Stephanie Sansom, PhD


                 National HIV Prevention Conference
                         August 14-17, 2011

           National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention
           Division of HIV/AIDS Prevention
Objective
□ Develop a tool that state and local health departments
  can use to measure the impact of HIV prevention budget
  cuts on their jurisdictions
   ■   To examine the effect of budget cuts on people living with or at
       risk for HIV
   ■   To estimate the impact of the budget cuts on HIV incidence
   ■   To compare different budget allocation scenarios
Budget and Program Data
□ Data on selected jurisdictions were provided by the
  California State Office of AIDS
    Included jurisdictions that did not receive direct funds from CDC
    Excluded Los Angeles and San Francisco
□ Type of data
    Federal and state HIV prevention budgets administered by the
     Office of AIDS
    Number of local agencies that received HIV prevention funds
    Number of clients served
       □ Number of positives who received test results
       □ Number of unique clients of health education and risk reduction
         (HERR) services
HIV Prevention Budget Allocated
                  by Prevention Activities



                       Pre-cut scenario
                                          21% ↓


                                                  70% ↓




* LA and SF excluded
Testing and Partner Services




* LA and SF excluded
Health Education and Risk Reduction (HERR)




* LA and SF excluded
Summary of Prevention Services
                                                             Pre-cut &:                FY0910      Reduction (%)
                                                          FY0506-FY0708
Total prevention budget                                        $21,849,923         $5,860,723     $15,989,200 (73)
Funded local health jurisdictions                                           59              15            44 (75)
Funded prevention agencies                                               143 #              36           107 (75)
Testing and partner services
 Budget                                                          $4,024,634        $3,160,148       $864,486 (21)
 Number of tests performed                                            83,799             52,590        31,209 (37)
 Number of positives notified of test result                              813              465           348 (43)
Health education and risk reduction (HERR)
 Budget                                                        $17,825,289         $2,700,575     $15,124,714 (85)
 Number of unique clients                                             11,784              3,386         8,398 (71)
 Number of unique positive clients                                      2,884             1,100         1,784 (62)
 Number of unique negative clients                                      8,900             2,286         6,614 (74)
* LA and SF excluded
& We took the average values from FY0506 to FY0708 for the pre-cut scenario.
# Number of funded local prevention agencies was not available in FY0506 and FY0607.
Methods
□ Estimate the number of new infections associated with
  the budget cuts
    Prevention service reduction
     Number of clients served (pre-cut scenario) – Number of clients
     served (FY0910)
    Estimate HIV transmission: Bernoulli process model
        □ Testing and partner services
        □ Health education and risk reduction (HERR)
   ■   Compare different budget allocation scenarios
Summary of Inputs to Bernoulli Model
Parameter                             Value (Range)            Source
Per-act transmission probability
  Vaginal receptive                    0.08% (0.06–0.11%) Boily et al. Lancet Infect Dis 2009; 9(2): 118-
                                                               29.
  Vaginal insertive                    0.04% (0.01–0.14%)
  Anal receptive                         1.40% (0.2–2.5%) Baggaley et al. Int J Epidemiol 2010; 39(4):
                                                               1048-63.
  Anal insertive                            0.70% (0-1.3%)
Condom effectiveness                        90% (85–95%) Pinkerton et al. Soc Sci Med 1997; 44(9):
                                                            1303-12
Annual nb. of sex acts all partners             85 (26-365) Long et al. Ann Intern Med 2010; 153(12):
                                                            778-89
Annual nb. of sexual partners
  HET                                             1.1 (1-20) Long et al. Ann Intern Med 2010; 153(12):
                                                             778-89
  IDU                                               3 (1-20) Metsch et al. NHPC2007
  MSM                                             3.5 (1-20) NHBS
ART effectiveness (reduction in              90% (80-99%) Attia et al. AIDS 2009; 23:1397-1404. (Bunnell
                                                              et al. Del Romero et al. Donnell et al.)
infectivity)
Proportion new diagnosis among               60% (40-80%) Hanna et al. JAIDS 2009; 51(5): p. 609-14.
                                                              ETI data
positives who received test results
Summary of Inputs to Bernoulli Model (cont’)
Parameter                                     Value (Range)          Source
HIV prevalence in California
  HET                                           1.0%(0.75–1.25%) CDC 2001
  IDU                                              5.9%(4–10.2%) Friedman et al. J Urban Health 2005;
                                                                 82(3): 434-45
  MSM                                         19.1%(12.8–25.35%) Xia et al. JAIDS 2006; 41(2): 238-45
Proportion of protected sex acts
  Undiagnosed positives & those at risk              50% (0-100%) Gary Marks
  Positive aware w/o particip ating in HERR        75% (50-100%) Gary Marks
Reduction in UAV for positive aware people           53% (45-60%) Marks et al. JAIDS 2005; 39(4): 446-53.
Effect size of HERR for positives                     18% (0-40%) Options/Opciones Project,WiLLOW,
                                                                    Healthy Living Project, Healthy
                                                                    Relationships, CLEAR
Effect size of HERR for negatives                      8% (0-20%) INSIGHT,Focus on the Future, Sister to
                                                                    Sister
Proportion linked to care                            69% (66-71%) Marks et al. AIDS 2010; 24(17): 2665-78.
Proportion of positive aware in care who           54.5% (40-70%) Marks et al. AIDS 2006; 20: 1447-50.
achieve viral load suppression
Estimates of Budget Cut Impact

                                       Testing and      Health education        Total
                                     partner services   and risk reduction
                                                              (HERR)
Budget cut ($)                             $ 864,486         $15,124,714      $15,989,200
Estimated number of new infections
associated with budget cuts
  HET                                            1.4                  1.9                3.3
  IDU                                            0.3                  0.3                0.6
  MSM                                           24.9                37.2                62.1
 Total                                          26.6                39.4            66.0

Expected life-time HIV treatment         $ 9,760,335        $ 14,476,414     $ 24,236,749
cost generated

Number of new infections per one               30.75                1.92                4.13
million dollars cut



 * LA and SF excluded
Compare Budget Allocation Scenarios
                                                      Hypothetical pre-cut   Actual allocation in
                                                       allocation scenario        FY0910
Total prevention budget                                  $5,860,723 (100%)    $5,860,723 (100%)
     Testing and partner services                         $1,079,512 (18%)     $3,160,148 (54%)
     Health education and risk reduction (HERR)           $4,781,211 (82%)     $2,700,575 (46%)
Number of local health jurisdictions funded                            59                     15
Number of positives notified of test result                           159                    465
Number of unique HERR clients                                        5,995                 3,386
     Number of unique positive HERR clients                          1,467                 1,100
     Number of unique negative HERR clients                          4,527                 2,286
Estimated number of infections associated with cuts                  88.4                   66.0
     Testing and partner services                                     58.9                   26.6
     HERR for positive                                                22.2                   29.0
     HERR for negative                                                 7.2                   10.4
Expected life-time treatment cost generated                  $ 32,439,520          $ 24,236,749

    * LA and SF excluded
Limitations

□ We did not include Los Angeles and San Francisco
  because data for the two jurisdictions were incomplete.
□ Only the first generation of transmissions were captured
  in the impact estimates.
□ We assumed the reductions in prevention services
  were the same proportionately across risk groups.
□ Data inputs for Bernoulli model had varying degrees of
  uncertainty. These were covered in sensitivity analyses.
Conclusions
□ Over $15 million was cut from HIV prevention in FY0910
      Testing: we estimated 31,209 fewer tests were performed, 384 fewer
       positives were notified of their infection
      Health education and risk reduction (HERR): 1,784 fewer positive clients
       and 6,614 fewer negative clients were served

□ Impact of budget cuts in FY0910
      Estimated 66 new infections were associated with the cuts in one year
      The first year new infections were expected to generate $24 million in HIV
       life-time treatment cost

□ Budget allocation in FY0910 appeared to partially reduce the
  impact of budget cuts
      Allocate larger proportion of budget to testing
      Fewer new infections would occur
 * LA and SF excluded
Acknowledgements

□ Richard Wolitski, Choi Wan, Jeffrey Brock, Robert
  Swayzer, Dale Stratford, Dwight Dunbar; Division of
  HIV/AIDS Prevention, Centers for Disease Control and
  Prevention

□ Michelle Roland, Susan Sabatier, Karen Mark, Kevin
  Sitter, David Webb, Christine Nelson, Karen Doran,
  Charlene Anderson, Brian Lew, Phillip Morris, Matt
  Facer, Amy Kile-Puente, Mark Damesyn, Schenelle
  Flores; Office of AIDS, California Department of Public
  Health
Questions?


For more information please contact: Feng Lin (Flin@cdc.gov)

Centers for Disease Control and Prevention
1600 Clifton Road NE, Atlanta, GA 30333
Telephone: 1-800-CDC-INFO (232-4636)/TTY: 1-888-232-6348
E-mail: cdcinfo@cdc.gov Web: http://www.cdc.gov

The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of
the Centers for Disease Control and Prevention.




                    National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention
                    Division of HIV/AIDS Prevention

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Estimated Impact of HIV Prevention Budget Cuts for Selected Jurisdictions in California

  • 1. Estimated Impact of HIV Prevention Budget Cuts for Selected Jurisdictions in California Feng Lin, PhD; Arielle Lasry, PhD; Annette Ladan, MS; Stephanie Sansom, PhD National HIV Prevention Conference August 14-17, 2011 National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention Division of HIV/AIDS Prevention
  • 2. Objective □ Develop a tool that state and local health departments can use to measure the impact of HIV prevention budget cuts on their jurisdictions ■ To examine the effect of budget cuts on people living with or at risk for HIV ■ To estimate the impact of the budget cuts on HIV incidence ■ To compare different budget allocation scenarios
  • 3. Budget and Program Data □ Data on selected jurisdictions were provided by the California State Office of AIDS  Included jurisdictions that did not receive direct funds from CDC  Excluded Los Angeles and San Francisco □ Type of data  Federal and state HIV prevention budgets administered by the Office of AIDS  Number of local agencies that received HIV prevention funds  Number of clients served □ Number of positives who received test results □ Number of unique clients of health education and risk reduction (HERR) services
  • 4. HIV Prevention Budget Allocated by Prevention Activities Pre-cut scenario 21% ↓ 70% ↓ * LA and SF excluded
  • 5. Testing and Partner Services * LA and SF excluded
  • 6. Health Education and Risk Reduction (HERR) * LA and SF excluded
  • 7. Summary of Prevention Services Pre-cut &: FY0910 Reduction (%) FY0506-FY0708 Total prevention budget $21,849,923 $5,860,723 $15,989,200 (73) Funded local health jurisdictions 59 15 44 (75) Funded prevention agencies 143 # 36 107 (75) Testing and partner services Budget $4,024,634 $3,160,148 $864,486 (21) Number of tests performed 83,799 52,590 31,209 (37) Number of positives notified of test result 813 465 348 (43) Health education and risk reduction (HERR) Budget $17,825,289 $2,700,575 $15,124,714 (85) Number of unique clients 11,784 3,386 8,398 (71) Number of unique positive clients 2,884 1,100 1,784 (62) Number of unique negative clients 8,900 2,286 6,614 (74) * LA and SF excluded & We took the average values from FY0506 to FY0708 for the pre-cut scenario. # Number of funded local prevention agencies was not available in FY0506 and FY0607.
  • 8. Methods □ Estimate the number of new infections associated with the budget cuts  Prevention service reduction Number of clients served (pre-cut scenario) – Number of clients served (FY0910)  Estimate HIV transmission: Bernoulli process model □ Testing and partner services □ Health education and risk reduction (HERR) ■ Compare different budget allocation scenarios
  • 9. Summary of Inputs to Bernoulli Model Parameter Value (Range) Source Per-act transmission probability Vaginal receptive 0.08% (0.06–0.11%) Boily et al. Lancet Infect Dis 2009; 9(2): 118- 29. Vaginal insertive 0.04% (0.01–0.14%) Anal receptive 1.40% (0.2–2.5%) Baggaley et al. Int J Epidemiol 2010; 39(4): 1048-63. Anal insertive 0.70% (0-1.3%) Condom effectiveness 90% (85–95%) Pinkerton et al. Soc Sci Med 1997; 44(9): 1303-12 Annual nb. of sex acts all partners 85 (26-365) Long et al. Ann Intern Med 2010; 153(12): 778-89 Annual nb. of sexual partners HET 1.1 (1-20) Long et al. Ann Intern Med 2010; 153(12): 778-89 IDU 3 (1-20) Metsch et al. NHPC2007 MSM 3.5 (1-20) NHBS ART effectiveness (reduction in 90% (80-99%) Attia et al. AIDS 2009; 23:1397-1404. (Bunnell et al. Del Romero et al. Donnell et al.) infectivity) Proportion new diagnosis among 60% (40-80%) Hanna et al. JAIDS 2009; 51(5): p. 609-14. ETI data positives who received test results
  • 10. Summary of Inputs to Bernoulli Model (cont’) Parameter Value (Range) Source HIV prevalence in California HET 1.0%(0.75–1.25%) CDC 2001 IDU 5.9%(4–10.2%) Friedman et al. J Urban Health 2005; 82(3): 434-45 MSM 19.1%(12.8–25.35%) Xia et al. JAIDS 2006; 41(2): 238-45 Proportion of protected sex acts Undiagnosed positives & those at risk 50% (0-100%) Gary Marks Positive aware w/o particip ating in HERR 75% (50-100%) Gary Marks Reduction in UAV for positive aware people 53% (45-60%) Marks et al. JAIDS 2005; 39(4): 446-53. Effect size of HERR for positives 18% (0-40%) Options/Opciones Project,WiLLOW, Healthy Living Project, Healthy Relationships, CLEAR Effect size of HERR for negatives 8% (0-20%) INSIGHT,Focus on the Future, Sister to Sister Proportion linked to care 69% (66-71%) Marks et al. AIDS 2010; 24(17): 2665-78. Proportion of positive aware in care who 54.5% (40-70%) Marks et al. AIDS 2006; 20: 1447-50. achieve viral load suppression
  • 11. Estimates of Budget Cut Impact Testing and Health education Total partner services and risk reduction (HERR) Budget cut ($) $ 864,486 $15,124,714 $15,989,200 Estimated number of new infections associated with budget cuts HET 1.4 1.9 3.3 IDU 0.3 0.3 0.6 MSM 24.9 37.2 62.1 Total 26.6 39.4 66.0 Expected life-time HIV treatment $ 9,760,335 $ 14,476,414 $ 24,236,749 cost generated Number of new infections per one 30.75 1.92 4.13 million dollars cut * LA and SF excluded
  • 12. Compare Budget Allocation Scenarios Hypothetical pre-cut Actual allocation in allocation scenario FY0910 Total prevention budget $5,860,723 (100%) $5,860,723 (100%) Testing and partner services $1,079,512 (18%) $3,160,148 (54%) Health education and risk reduction (HERR) $4,781,211 (82%) $2,700,575 (46%) Number of local health jurisdictions funded 59 15 Number of positives notified of test result 159 465 Number of unique HERR clients 5,995 3,386 Number of unique positive HERR clients 1,467 1,100 Number of unique negative HERR clients 4,527 2,286 Estimated number of infections associated with cuts 88.4 66.0 Testing and partner services 58.9 26.6 HERR for positive 22.2 29.0 HERR for negative 7.2 10.4 Expected life-time treatment cost generated $ 32,439,520 $ 24,236,749 * LA and SF excluded
  • 13. Limitations □ We did not include Los Angeles and San Francisco because data for the two jurisdictions were incomplete. □ Only the first generation of transmissions were captured in the impact estimates. □ We assumed the reductions in prevention services were the same proportionately across risk groups. □ Data inputs for Bernoulli model had varying degrees of uncertainty. These were covered in sensitivity analyses.
  • 14. Conclusions □ Over $15 million was cut from HIV prevention in FY0910  Testing: we estimated 31,209 fewer tests were performed, 384 fewer positives were notified of their infection  Health education and risk reduction (HERR): 1,784 fewer positive clients and 6,614 fewer negative clients were served □ Impact of budget cuts in FY0910  Estimated 66 new infections were associated with the cuts in one year  The first year new infections were expected to generate $24 million in HIV life-time treatment cost □ Budget allocation in FY0910 appeared to partially reduce the impact of budget cuts  Allocate larger proportion of budget to testing  Fewer new infections would occur * LA and SF excluded
  • 15. Acknowledgements □ Richard Wolitski, Choi Wan, Jeffrey Brock, Robert Swayzer, Dale Stratford, Dwight Dunbar; Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention □ Michelle Roland, Susan Sabatier, Karen Mark, Kevin Sitter, David Webb, Christine Nelson, Karen Doran, Charlene Anderson, Brian Lew, Phillip Morris, Matt Facer, Amy Kile-Puente, Mark Damesyn, Schenelle Flores; Office of AIDS, California Department of Public Health
  • 16. Questions? For more information please contact: Feng Lin (Flin@cdc.gov) Centers for Disease Control and Prevention 1600 Clifton Road NE, Atlanta, GA 30333 Telephone: 1-800-CDC-INFO (232-4636)/TTY: 1-888-232-6348 E-mail: cdcinfo@cdc.gov Web: http://www.cdc.gov The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention Division of HIV/AIDS Prevention