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Super Vivere
Reflections on Living Long and
         Ageing Well


         Dr Maeve Rea
           Susie Rea
Outline
•   Background and Introduction
•   Methodology used
•   Structured questions
•   Life stories
•   Summary points
Background
Nonagenarian
Numbers are
  growing
Life Expectancy across World
Centenarians on the Rise




Numbers of US Centenarians are expected to rise exponentially between now and
2050.
In 2050
•1 in 10 in Europe
 80+ yrs
Survivors, Delayers, Escapers

• ‘survivors’, 42%

• ‘delayers, 45%

• ‘escapers’, 13%
                     Perls T, Boston
Healthy
Ageing
‘escaper’
OKINAWA Study


       ‘Land of
       immortals’
Factors which contribute
  to ‘successful ageing’
GEnetics of Healthy Ageing
GEnetics
    -3200 pairs of 90+ brothers and sisters
                             across Europe
                          EU-funded study
        -Study to look at genes for healthy
                                     ageing
Nuclear and mitochondrial Genes
Population structure among GEHA study

                       C1 vs C2




                            Cluster 2


           Cluster 3




                                        Cluster 1
Whole Genome Scan
Survivors
• Survivors interest us all.
• They tell us the possibilities for our own
  survival.
• We are fascinated by the stories of people
  who survive against the odds in difficult or
  extreme circumstances.
Isa
                                             • It in my genes
                                             • My father was
                                               102
                                             • I worked hard
                                             • A glass of wine




Belfast Telegraph Saturday 20 January 2010
Bridging Genes and Gerontology




Seeing the world with a different
             lens
Background hypotheses
• Life stories may help us understand something
  of the personhood of the 90 year old
• What makes them a survivor?
• What value system have they adopted?
• How do they see their past, their future, their
  peers?
• What are the common strands of personality
  or memory and coping skills with their
  siblings, if any?
Visual Images

• We all have a visual image and form which is
  part of the story which we tell
• Both are part of our personhood and are
  interdependent
• Combining both visual and verbal stories will
  enhance the richness of the life story
Methods
GeHA Recruitment
•   Italy              5 pairs
•   Poland             5 pairs
•   Finland            4 pairs and 1 trio
•   Northern Ireland   10 pairs and 3 trio
•   Greece
•   France
•   Belgium
•   Germany
•   Ukraine
•   Denmark
Narrative
• ‘Tell me your life story ‘

•   Research teams already knew sibling pairs or trios
•   Already had established a rapport with sibling pairs and families
•   Sibling pairs or trios who consented loved giving their stories
•   Written consent for recording and photographs
Structured Questions
•   What age do you feel?
•   What do you think makes you a survivor?
•   How makes you happy in your life?
•   How do you view the future?
Northern Ireland
Thomas 94 and Joyce 96
       Belfast
Thomas
William at 96 years young, supposes that
his

‘plain diet – not too much sweet stuff or
sugar’

has been important in his longevity.

Norman at 95 years says that he had

“No junk food”

“ only good food”
Samuel is 95,
‘going on 25’,
and considers
that he has
always


‘been
interested in
people and
interested in
life’.
Dorothy in her
93rd year, tells us
that she has


‘always made the
best of things’
Ellie at 100 reports that

  “Father and
  mother lived
  long”

  “I had cousins
  too”

  “The men didn’t
  live so long”
Kelvin, Sarah and Kathleen

         4 siblings
          Belfast
Anne, Kathleen, Sarah, Kelvin
What makes you a Survivor?
              N Ireland
Kathleen 92   ‘good health and my daughter living with me’
Kelvin 93     ‘just my genes; my cousin was 99, my aunt in her 90s’
Sarah 94‘     keeping in touch with news and everything’
Grace 94      ‘my father lived to 94’
Jane 95       ‘good food when we were young’
Pauline 95    ‘its my Guardian Angel; she looks after my mishaps’
Mary 99       ‘ hard work, it was hard work’
Ellen 96      ‘ if you work hard you just survive’
Sarah 94      ‘ we hadn’t very much, but our parents were good’
Lilian 100    ‘I just worked on, I didn’t think of myself’
Dorothy 93    ‘It must be my genes; my mother was 90, my aunt 95 and
              another one 94 on father’s side’
Thomas 94     ‘ My father lived to 98; good care and attention’
Norman 96     ‘Hard work that’s the secret’
Poland
Pelagia




‘I worked hard; rather hard.
 I did not smoke’
Jadwiga




‘my
grandmother
lived long; I
like to do
crosswords’
Stranilawa
B   Bradnaska
What makes you a Survivor?
               Poland
Pelagia 93      ‘I worked hard, rather hard; I did not smoke’
Jadwiga 94      ‘my grandmother lived long; I like to do crosswords’

Koldra 93       ‘hard-bitten in work; fed healthy food in the forest’
Marcjanna 94    ‘I tell the priest I drink vodka every day; but it isn’t true!’

Janina 96       ‘joyful; they say I look young’
Fausta 99       ‘don’t know’

Stranilawa 92   ‘I enjoyed a bit of vodka to help me’
Bradnaska 90    ‘ I have always worked; I have been working’
Bologna

  Italy
Antonietta 96

Well I feel a
‘

bit old-
but my head is
still healthy,
even if my legs
aren’t’ so
good’
Antionietta’s
Kitchen


‘We had cod-
liver oil to
drink every
morning till
we were 15
or 16’
This is me

‘One of us
always wants
to be right

But I won’t
tell you which
one!’
Aussanta 99
‘Getting old
is no fun’

’life has
been hard’
Giovanna
Giovanna and Dante
What makes you a Survivor?
                 Italy
Antonietta93   ‘they gave us cod liver oil to drink, till we were 15 or 16’
Assunta 100    ‘working so hard, heavy jobs’

Augusta 95     ‘Health, a quiet life;I don’t feel melancholy’
Giula 94       ‘working hard, working a lot’

Germana 96     ‘working hard, I had 4 men to look after!’
Fausta 99      ‘don’t know’

Virginia 97    ‘I have been happy, our mother loved us’
Adelma 90      ‘ I have always been healthy; I have been working’

Dante 96       ‘I feel young, I don’t have ill health’
Giovanna 96    ‘I have always lived day by day; I don’t know’
Finland
Karl



  ‘ the last
package from
 my mother
saved my life’
EVA


      ‘This is my
        country
      I can speak
        Finnish’
Hilkka, Pulmu and Maija
What makes you a Survivor?
               Finland
Maila 93    ‘hard to say-well genes’
Meeri 98    ‘my father was 91; I have lived to 98’
Hilkka 95    ‘it’s how it plays out and luck’
Pulmu 93    ‘ Heavenly care and strength for each day dawning’
Maija       ‘You settle for what comes along’
Matti 94    ‘a joyful character, that doesn’t worry unnecessarily’
Anna 90     ‘I was only ill last summer for the first time’
Laura 91    ‘it might be my fighting spirit’
Sylvie90    ‘it’s no good taking the gloomy view’
Karl 95     ‘ the last package from my mother saved my life’
Eva 92      ‘this is my country now, I can speak Finnish’
Genes                                      Physical Activity
                      Good Health



                                                    Social Connections
        Eating well          90 year
                               old
                             Survivor                  Don’t Worry

   Alcohol
     ???

                                    Luck      Mental Activity



          Smoking
Summary

-Maintain mental and physical health
-Hard work and determination
-Eat properly
-Good sense of Humour
-Good family and social support

-Choose long-living parents!
Summary

Is this what we see in our sibling pairs
who start with a good gene capital, but
then build upon this with a common,
perhaps good family, life experience and
this facilitates their ‘ageing-well profile’?
Can we slowing Ageing ?
Keep healthy, Keep Active
All Photos copyright Susie Rea

     http://www.susierea.com/
Broccoli
Green Tea
RED WINE
Kaplan-Meier survival curves for individual subjects with diet score up to 3 and 4 or more




                                            Trichopoulou, A. et al. BMJ 1995;311:1457-1460




Copyright ©1995 BMJ Publishing Group Ltd.
Kaplan-Meier Curves for Number of Healthful Lifestyle Factors




                     Knoops, K. T. B. et al. JAMA 2004;292:1433-1439.



Copyright restrictions may apply.
Social Integration
Support
Confucius Temple
Summary
Throughout the interviews, across all the
countries, we seem to see

a sense of positivity
optimism
a self deprecating sense of humour
adaptability
a feisty independence

emerging as the phenotype for the
successful ageing personality.
GENES   Environment
        Behaviours
Special thanks to

             GEHA teams
                   in
Italy, Poland, Finland and N Ireland
     Laura and Elisa and Claudio
            Kasia and Ewa
     Antii and medical students
           Anne and Susie
Digital Stories

•   Combine Narrative and Photographs
•   90 year old sibling pairs across Europe
•   Powerful empowerment tool for Older People
•   Dissemination tool for GEHA and ACUME2
Changing Ageing Partnership
        (Queens University Initative)



-empowering older people
-enhancing positive attitudes
to ageing
-giving older people a voice
Questions ?
i.rea@qub.ac.uk

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Super vivere

  • 1. Super Vivere Reflections on Living Long and Ageing Well Dr Maeve Rea Susie Rea
  • 2. Outline • Background and Introduction • Methodology used • Structured questions • Life stories • Summary points
  • 6. Centenarians on the Rise Numbers of US Centenarians are expected to rise exponentially between now and 2050.
  • 7. In 2050 •1 in 10 in Europe 80+ yrs
  • 8.
  • 9. Survivors, Delayers, Escapers • ‘survivors’, 42% • ‘delayers, 45% • ‘escapers’, 13% Perls T, Boston
  • 11. OKINAWA Study ‘Land of immortals’
  • 12.
  • 13. Factors which contribute to ‘successful ageing’
  • 14. GEnetics of Healthy Ageing GEnetics -3200 pairs of 90+ brothers and sisters across Europe EU-funded study -Study to look at genes for healthy ageing
  • 16.
  • 17. Population structure among GEHA study C1 vs C2 Cluster 2 Cluster 3 Cluster 1
  • 18.
  • 20. Survivors • Survivors interest us all. • They tell us the possibilities for our own survival. • We are fascinated by the stories of people who survive against the odds in difficult or extreme circumstances.
  • 21. Isa • It in my genes • My father was 102 • I worked hard • A glass of wine Belfast Telegraph Saturday 20 January 2010
  • 22. Bridging Genes and Gerontology Seeing the world with a different lens
  • 23. Background hypotheses • Life stories may help us understand something of the personhood of the 90 year old • What makes them a survivor? • What value system have they adopted? • How do they see their past, their future, their peers? • What are the common strands of personality or memory and coping skills with their siblings, if any?
  • 24. Visual Images • We all have a visual image and form which is part of the story which we tell • Both are part of our personhood and are interdependent • Combining both visual and verbal stories will enhance the richness of the life story
  • 26. GeHA Recruitment • Italy 5 pairs • Poland 5 pairs • Finland 4 pairs and 1 trio • Northern Ireland 10 pairs and 3 trio • Greece • France • Belgium • Germany • Ukraine • Denmark
  • 27. Narrative • ‘Tell me your life story ‘ • Research teams already knew sibling pairs or trios • Already had established a rapport with sibling pairs and families • Sibling pairs or trios who consented loved giving their stories • Written consent for recording and photographs
  • 28. Structured Questions • What age do you feel? • What do you think makes you a survivor? • How makes you happy in your life? • How do you view the future?
  • 30. Thomas 94 and Joyce 96 Belfast
  • 32. William at 96 years young, supposes that his ‘plain diet – not too much sweet stuff or sugar’ has been important in his longevity. Norman at 95 years says that he had “No junk food” “ only good food”
  • 33. Samuel is 95, ‘going on 25’, and considers that he has always ‘been interested in people and interested in life’.
  • 34. Dorothy in her 93rd year, tells us that she has ‘always made the best of things’
  • 35. Ellie at 100 reports that “Father and mother lived long” “I had cousins too” “The men didn’t live so long”
  • 36. Kelvin, Sarah and Kathleen 4 siblings Belfast
  • 38. What makes you a Survivor? N Ireland Kathleen 92 ‘good health and my daughter living with me’ Kelvin 93 ‘just my genes; my cousin was 99, my aunt in her 90s’ Sarah 94‘ keeping in touch with news and everything’ Grace 94 ‘my father lived to 94’ Jane 95 ‘good food when we were young’ Pauline 95 ‘its my Guardian Angel; she looks after my mishaps’ Mary 99 ‘ hard work, it was hard work’ Ellen 96 ‘ if you work hard you just survive’ Sarah 94 ‘ we hadn’t very much, but our parents were good’ Lilian 100 ‘I just worked on, I didn’t think of myself’ Dorothy 93 ‘It must be my genes; my mother was 90, my aunt 95 and another one 94 on father’s side’ Thomas 94 ‘ My father lived to 98; good care and attention’ Norman 96 ‘Hard work that’s the secret’
  • 40. Pelagia ‘I worked hard; rather hard. I did not smoke’
  • 42. Stranilawa B Bradnaska
  • 43. What makes you a Survivor? Poland Pelagia 93 ‘I worked hard, rather hard; I did not smoke’ Jadwiga 94 ‘my grandmother lived long; I like to do crosswords’ Koldra 93 ‘hard-bitten in work; fed healthy food in the forest’ Marcjanna 94 ‘I tell the priest I drink vodka every day; but it isn’t true!’ Janina 96 ‘joyful; they say I look young’ Fausta 99 ‘don’t know’ Stranilawa 92 ‘I enjoyed a bit of vodka to help me’ Bradnaska 90 ‘ I have always worked; I have been working’
  • 45. Antonietta 96 Well I feel a ‘ bit old- but my head is still healthy, even if my legs aren’t’ so good’
  • 46. Antionietta’s Kitchen ‘We had cod- liver oil to drink every morning till we were 15 or 16’
  • 47. This is me ‘One of us always wants to be right But I won’t tell you which one!’
  • 48. Aussanta 99 ‘Getting old is no fun’ ’life has been hard’
  • 49.
  • 52. What makes you a Survivor? Italy Antonietta93 ‘they gave us cod liver oil to drink, till we were 15 or 16’ Assunta 100 ‘working so hard, heavy jobs’ Augusta 95 ‘Health, a quiet life;I don’t feel melancholy’ Giula 94 ‘working hard, working a lot’ Germana 96 ‘working hard, I had 4 men to look after!’ Fausta 99 ‘don’t know’ Virginia 97 ‘I have been happy, our mother loved us’ Adelma 90 ‘ I have always been healthy; I have been working’ Dante 96 ‘I feel young, I don’t have ill health’ Giovanna 96 ‘I have always lived day by day; I don’t know’
  • 54. Karl ‘ the last package from my mother saved my life’
  • 55.
  • 56.
  • 57.
  • 58.
  • 59. EVA ‘This is my country I can speak Finnish’
  • 60.
  • 62. What makes you a Survivor? Finland Maila 93 ‘hard to say-well genes’ Meeri 98 ‘my father was 91; I have lived to 98’ Hilkka 95 ‘it’s how it plays out and luck’ Pulmu 93 ‘ Heavenly care and strength for each day dawning’ Maija ‘You settle for what comes along’ Matti 94 ‘a joyful character, that doesn’t worry unnecessarily’ Anna 90 ‘I was only ill last summer for the first time’ Laura 91 ‘it might be my fighting spirit’ Sylvie90 ‘it’s no good taking the gloomy view’ Karl 95 ‘ the last package from my mother saved my life’ Eva 92 ‘this is my country now, I can speak Finnish’
  • 63. Genes Physical Activity Good Health Social Connections Eating well 90 year old Survivor Don’t Worry Alcohol ??? Luck Mental Activity Smoking
  • 64. Summary -Maintain mental and physical health -Hard work and determination -Eat properly -Good sense of Humour -Good family and social support -Choose long-living parents!
  • 65. Summary Is this what we see in our sibling pairs who start with a good gene capital, but then build upon this with a common, perhaps good family, life experience and this facilitates their ‘ageing-well profile’?
  • 66. Can we slowing Ageing ?
  • 68.
  • 69.
  • 70. All Photos copyright Susie Rea http://www.susierea.com/
  • 71.
  • 75. Kaplan-Meier survival curves for individual subjects with diet score up to 3 and 4 or more Trichopoulou, A. et al. BMJ 1995;311:1457-1460 Copyright ©1995 BMJ Publishing Group Ltd.
  • 76. Kaplan-Meier Curves for Number of Healthful Lifestyle Factors Knoops, K. T. B. et al. JAMA 2004;292:1433-1439. Copyright restrictions may apply.
  • 80.
  • 81. Summary Throughout the interviews, across all the countries, we seem to see a sense of positivity optimism a self deprecating sense of humour adaptability a feisty independence emerging as the phenotype for the successful ageing personality.
  • 82. GENES Environment Behaviours
  • 83. Special thanks to GEHA teams in Italy, Poland, Finland and N Ireland Laura and Elisa and Claudio Kasia and Ewa Antii and medical students Anne and Susie
  • 84. Digital Stories • Combine Narrative and Photographs • 90 year old sibling pairs across Europe • Powerful empowerment tool for Older People • Dissemination tool for GEHA and ACUME2
  • 85. Changing Ageing Partnership (Queens University Initative) -empowering older people -enhancing positive attitudes to ageing -giving older people a voice