1. Transforming JDRF Research.
Impacting Lives.
Julia L . Greenstein, PhD
AVP Cure Therapies
April 10, 2012
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2. JDRF Global Leadership in T1D Research
 Largest T1D non-profit: $1.6B in
research funded over past 40 years
 In FY11 JDRF funded:
- $116 million direct support
- In 18 countries
- Including over 50 clinical trials
 More than 80% of JDRF expenditures directly
support research and research-related education
 Forbes magazine called JDRF “...a tightly run
organization that puts almost every dollar spent to
work curing disease....”
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3. Research Agenda of Hope for all T1D Patients
 Remains #1 priority for JDRF
 Recent explosion of new information
about immune system & beta cells
 Creating exciting new paths to a cure
Julia – Cure Importance
 Leveraging efforts to both curing &
preventing T1D
CURING T1D to
remove it from the
lives of our loved
ones
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4. Research Agenda of Hope for all T1D Patients
 Until we can cure & prevent T1D we
are committed to improving lives
 The past 40 years have seen
significant improvements in care
Aaron – Why Treat?
 Translating into longer life
expectancy
Develop better  More can be done to improve the
ways to TREAT T1D quality of life for everyone living
allowing a better with T1D
quality of life
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5. Research Agenda of Hope for all T1D Patients
 Growth of T1D is accelerating
around the world
 Dramatic rise especially among
young children
 Children born to a family with T1D
Preventing the autoimmune
have a 10 time greater risk of
process from ever starting developing the disease
Stopping and reversing the
autoimmune process early
 Only prevention can alter this trend
to maintain insulin
independence
and protect future generations
from T1D
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6. JDRF Research Priorities
Regenerating new beta cells Artificial pancreas systems Preventing the autoimmune
process from ever starting
Encapsulation of alternative Novel insulins and other
beta cell sources blood sugar control drugs Stopping and reversing the
autoimmune process early
Immune therapies Diabetic eye disease to maintain insulin
independence
Diagnostic, measurement Complications prevention
and imaging tools
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7. Make A Difference - Get Involved!
 Give generously to speed
JDRF research to cure,
better treat and prevent
T1D
 Join a JDRF walk, ride,
gala or other fund-
raising event
 Volunteer at your local
JDRF chapter
 Participate in clinical
Learn more at: jdrf.org research
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