CPCSEA guideline

1. MBAHS
CPCSEA Guidelines for Laboratory
Animal Facility
Biswash Sapkota
Dept of Pharmacy
MBAHS, Hetauda, Nepal

2. MBAHS
Introduction and Goals
 CPCSEA stands for Committee for the Purpose of Control and Supervision of
Experiments on Animals
The goal of CPCSEA is to ensure that animals are not subjected to unnecessary
pains or suffering before, during or after performance of experiments on them.
The animal house facility is available to promote the teaching, training and
research facilities and to meet the growing demand for quality.
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3. MBAHS
Objectives
1. Experiments shall be performed in every case by or under the supervision of a
person duly qualified in that behalf, that is Degree or Diploma holders in
veterinary science or medicine or laboratory animal science of a university.
2. Experiments are performed with due care and humanity and that as far as
possible experiments involving operations are performed under the influence of
some anaesthetic of sufficient power to prevent the animals feeling pain.
3. Animals which, in the course of experiments under the influence of anaesthetics
are so injured that their recovery would involve serious suffering, are ordinarily
destroyed while still insensible.
4. Experiments on animal are avoided wherever it is possible to do so, as for
example in medical schools, hospitals, colleges and the like, if other teaching
devices such as books, models, films and the like, may equally suffice.
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4. MBAHS
Contd…
5. Experiments on larger animals are avoided when it is possible to achieve the
same results by experiments upon small laboratory animals like guinea- pigs,
rabbits, mice, rats etc.
6. As far as possible, experiments are not performed merely for the purpose of
acquiring manual skill;
7. Animals intended for the performance of experiments are properly looked after
both before and after experiments.
8. Suitable records are maintained with respect to experiments performed on
animals
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5. MBAHS
Veterinary Care
• Regular basis health monitoring of the animals is carried out to ascertain the health
status of pets and animals.
• Veterinary care is crucial to keep the animals content and healthy.
• Veterinarian keeps them under daily observation and monitors any behavioural
changes or sign of illness for animals.
• He supervises their diet and sanitation and contributes to the formulation of
appropriate policies and procedures for ancillary aspects of veterinary care.
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6. MBAHS
Animal care
• Laboratory houses rats, mice and rabbits.
• Each species of animals is housed in barrier maintained individual rooms to avoid
disease transmission and inter-species conflicts.
• All efforts are made to maintain the animals under controlled environmental
condition like temperature (22-26⁰C), relative humidity (60±10 %), 12 hrs
alternate light and dark cycle with 100% fresh air exchange in animal rooms and
uninterrupted power and water supply.
• The entire staffs ensures that every part of animal care including feeding,
watering, restraining, cage cleaning, record keeping and ordering of animals,
feeds, bedding materials and equipment from outside sources are monitored.
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7. MBAHS
Animal Ethics
The animals house is registered with CPCSEA, ministry of environment and forests,
Govt. of India and has an established institutional animal ethics committee(IAEC)
that advises the students, teachers/ researchers on facilities, policies and practices
concerning the care and use of animals accordance of CPCSEA guidelines.
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8. MBAHS
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