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Novel Corona Virus Infection
An Epidemic
Biplov Thapa
(Health Assistant)
What is Novel Corona Virus ?
2/14/2020 Biplov Thapa, Health Assistant 2
Fig; Corona Virus
 Coronaviruses (CoV) are large family viruses that causes illness
ranging from the common cold to more severe diseases such
as SARS, MERS etc.
 A Novel Coronavirus (nCoV) is a new strain, linear single
stranded RNA virus named as “2019 Novel Coronavirus” that
has not been previously identified in humans.
2/14/2020 Biplov Thapa, Health Assistant 3
Fig: Electron Microscopic view of corona virus
2/14/2020 Biplov Thapa, Health Assistant 4
Background:
The epidemic of “2019 Novel Coronavirus” was started from
Wuhan city of china on December-08, 2019, has infected
more than people than the Severe Acute Respiratory
Syndrome Corona Viruses(SARS- COV) and the Middle East
Respiratory Syndrome corona viruses (MERS CoV) combined.
2/14/2020 Biplov Thapa, Health Assistant 5
This was soon found to be significantly genetically related to
SARS CoV & other bat viruses. The initial cases were
associated with a seafood market in Wuhan. This suggested a
possible animal reservoir for this virus & suggested zoonotic
transmission i.e. Anthropozoonosis.
Later on, environmental samples obtained from the market
were found to be positive for 2019 nCoV. However, whilst the
viruses was found to have originally started among infected
animals . Most of subsequently reported cases were shown to
be caused by human to human transmission.
2/14/2020 Biplov Thapa, Health Assistant 6
2/14/2020 Biplov Thapa, Health Assistant 7
Beta corona viruses have caused major epidemics in the last 2
decades. In 2003 SARS CoV was discovered in china before
spreading globally, infecting 8098 people and killing 774. this
was found to be in zoonotic in origin & thought to have
started amongst a bat reservoir before infecting wild civet cats
& raccoon dogs that were being sold at live wild animal
markets destined fir human consumption.
In 2012, MERS CoV was discovered in Saudi Arabia before also
spreading globally resulting in 2506 confirmed cases & killing
862 people world wide. Again this started as zoonotic virus,
shown to move from camels to human & again thought to
have initially emerged from bats.
2/14/2020 Biplov Thapa, Health Assistant 8
How does Corona Virus transmits ??
There is clear evidence of human to human transmission,
possibly involving different MOT such as Direct Contact &
Droplet infection.
2/14/2020 Biplov Thapa, Health Assistant 9
What are the signs & symptoms of 2019 nCoV ?
2/14/2020 Biplov Thapa, Health Assistant 10
Common Symptoms:
2/14/2020 Biplov Thapa, Health Assistant 11
 Fever, headache
 Sore throat & Cough (develops after 2 to 7 days)
 Mild breathing difficulties i.e. RDS
 Tachycardia or palpitation
 Gastrointestinal issues such as diarrhea
 General body ache i.e. malaise
Severe symptoms:
 High grade fever i.e. 100.4°F or higher
 Severe respiratory distress syndrome i.e. dyspnea
 pneumonia
 Impaired Hepatic-Renal function
 Acute Renal failure
 Death
2/14/2020 Biplov Thapa, Health Assistant 12
Treatment:
Specific treatment is still not available.
WHO recommended clinical management of
severe acute respiratory infections when 2019
nCov is suspected :
1. Triage
2. Immediate implementation of IPC measures
3. Early supportive therapy & monitoring
4. Collection of specimen for laboratory diagnosis
5. Management of hypoxemic respiratory failure & ARDS
6. Management of septic shock
7. Prevention of complications
8. Specific anti- nCoV treatment
9. Special consideration for pregnant women
2/14/2020 Biplov Thapa, Health Assistant 13
WHO Online training course:
“EMERGECY RESPIRATORY VIRUS INCLUDING
2019nCoV METHODS FOR DETECTION,
PREVENTION, RESPOND TO & CONTROL”
2/14/2020 Biplov Thapa, Health Assistant 14
Current status:
As of Feburary-08, Saturday 34,816 cases of 2019 Novel
corona virus have been confirmed globally. The number of
confirmed cases of 2019nCov in China stands at 34,546 with
722 deaths. Outside China, 270 cases have been confirmed in
25 different countries with one case fatality in Philippines.
2/14/2020 Biplov Thapa, Health Assistant 15
2/14/2020 Biplov Thapa, Health Assistant 16
The epidemic rages on with an average of 2000 new cases
reported daily but on Friday, WHO said there had been fewer
reported infections in China in the past two days.
The WHO also released new data from 17,000 patients that
suggested 82% had a mild form of the disease, with 15%
considered severe cases & 3% critical.
2/14/2020 Biplov Thapa, Health Assistant 17
What do you think 2019 nCoV & Flu are
same ?
2/14/2020 Biplov Thapa, Health Assistant 18
Uh.. Uh
How can we prevent 2019 nCoV Infection ?
2/14/2020 Biplov Thapa, Health Assistant 19
2/14/2020 Biplov Thapa, Health Assistant 20
2/14/2020 Biplov Thapa, Health Assistant 21
2/14/2020 Biplov Thapa, Health Assistant 22
2/14/2020 Biplov Thapa, Health Assistant 23
2/14/2020 Biplov Thapa, Health Assistant 24
2/14/2020 Biplov Thapa, Health Assistant 25
2/14/2020 Biplov Thapa, Health Assistant 26
Top questions that are asked during WHO
press conference on“2019 nCoV”
2/14/2020 Biplov Thapa, Health Assistant 27
2/14/2020 Biplov Thapa, Health Assistant 28
2/14/2020 Biplov Thapa, Health Assistant 29
2/14/2020 Biplov Thapa, Health Assistant 30
2/14/2020 Biplov Thapa, Health Assistant 31
2/14/2020 Biplov Thapa, Health Assistant 32
2/14/2020 Biplov Thapa, Health Assistant 33
2/14/2020 Biplov Thapa, Health Assistant 34
2/14/2020 Biplov Thapa, Health Assistant 35
Effort by GoN to address 2019 Novel
Corona Virus Epidemic:
1. Awareness program
2. Establishment of “Help Desk”
3. “Rapid Response Team”
4. Hospital with “Isolation Bed” for suspected cases
5. Diagnostic laboratory services etc.
2/14/2020 Biplov Thapa, Health Assistant 36
2/14/2020 37
References:
WHO officials posts (www.who.int)
CDC officials articles (www.cdc.gov)
BBC News (www.bbc.com)
Chinese Newspaper posts & articles
Epidemiology & Disease Control Division, GoN
2/14/2020 Biplov Thapa, Health Assistant 38
Don’t you have any quires ?
2/14/2020 Biplov Thapa, Health Assistant 39
2/14/2020 Biplov Thapa, Health Assistant 40
“Stay Safe & Stay
Healthy”
Bye Bye …... Have a Good
day

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Novel corona virus infection by Biplov Thapa (Health Assistant)

  • 1. Novel Corona Virus Infection An Epidemic Biplov Thapa (Health Assistant)
  • 2. What is Novel Corona Virus ? 2/14/2020 Biplov Thapa, Health Assistant 2
  • 3. Fig; Corona Virus  Coronaviruses (CoV) are large family viruses that causes illness ranging from the common cold to more severe diseases such as SARS, MERS etc.  A Novel Coronavirus (nCoV) is a new strain, linear single stranded RNA virus named as “2019 Novel Coronavirus” that has not been previously identified in humans. 2/14/2020 Biplov Thapa, Health Assistant 3
  • 4. Fig: Electron Microscopic view of corona virus 2/14/2020 Biplov Thapa, Health Assistant 4
  • 5. Background: The epidemic of “2019 Novel Coronavirus” was started from Wuhan city of china on December-08, 2019, has infected more than people than the Severe Acute Respiratory Syndrome Corona Viruses(SARS- COV) and the Middle East Respiratory Syndrome corona viruses (MERS CoV) combined. 2/14/2020 Biplov Thapa, Health Assistant 5
  • 6. This was soon found to be significantly genetically related to SARS CoV & other bat viruses. The initial cases were associated with a seafood market in Wuhan. This suggested a possible animal reservoir for this virus & suggested zoonotic transmission i.e. Anthropozoonosis. Later on, environmental samples obtained from the market were found to be positive for 2019 nCoV. However, whilst the viruses was found to have originally started among infected animals . Most of subsequently reported cases were shown to be caused by human to human transmission. 2/14/2020 Biplov Thapa, Health Assistant 6
  • 7. 2/14/2020 Biplov Thapa, Health Assistant 7
  • 8. Beta corona viruses have caused major epidemics in the last 2 decades. In 2003 SARS CoV was discovered in china before spreading globally, infecting 8098 people and killing 774. this was found to be in zoonotic in origin & thought to have started amongst a bat reservoir before infecting wild civet cats & raccoon dogs that were being sold at live wild animal markets destined fir human consumption. In 2012, MERS CoV was discovered in Saudi Arabia before also spreading globally resulting in 2506 confirmed cases & killing 862 people world wide. Again this started as zoonotic virus, shown to move from camels to human & again thought to have initially emerged from bats. 2/14/2020 Biplov Thapa, Health Assistant 8
  • 9. How does Corona Virus transmits ?? There is clear evidence of human to human transmission, possibly involving different MOT such as Direct Contact & Droplet infection. 2/14/2020 Biplov Thapa, Health Assistant 9
  • 10. What are the signs & symptoms of 2019 nCoV ? 2/14/2020 Biplov Thapa, Health Assistant 10
  • 11. Common Symptoms: 2/14/2020 Biplov Thapa, Health Assistant 11  Fever, headache  Sore throat & Cough (develops after 2 to 7 days)  Mild breathing difficulties i.e. RDS  Tachycardia or palpitation  Gastrointestinal issues such as diarrhea  General body ache i.e. malaise
  • 12. Severe symptoms:  High grade fever i.e. 100.4°F or higher  Severe respiratory distress syndrome i.e. dyspnea  pneumonia  Impaired Hepatic-Renal function  Acute Renal failure  Death 2/14/2020 Biplov Thapa, Health Assistant 12 Treatment: Specific treatment is still not available.
  • 13. WHO recommended clinical management of severe acute respiratory infections when 2019 nCov is suspected : 1. Triage 2. Immediate implementation of IPC measures 3. Early supportive therapy & monitoring 4. Collection of specimen for laboratory diagnosis 5. Management of hypoxemic respiratory failure & ARDS 6. Management of septic shock 7. Prevention of complications 8. Specific anti- nCoV treatment 9. Special consideration for pregnant women 2/14/2020 Biplov Thapa, Health Assistant 13
  • 14. WHO Online training course: “EMERGECY RESPIRATORY VIRUS INCLUDING 2019nCoV METHODS FOR DETECTION, PREVENTION, RESPOND TO & CONTROL” 2/14/2020 Biplov Thapa, Health Assistant 14
  • 15. Current status: As of Feburary-08, Saturday 34,816 cases of 2019 Novel corona virus have been confirmed globally. The number of confirmed cases of 2019nCov in China stands at 34,546 with 722 deaths. Outside China, 270 cases have been confirmed in 25 different countries with one case fatality in Philippines. 2/14/2020 Biplov Thapa, Health Assistant 15
  • 16. 2/14/2020 Biplov Thapa, Health Assistant 16
  • 17. The epidemic rages on with an average of 2000 new cases reported daily but on Friday, WHO said there had been fewer reported infections in China in the past two days. The WHO also released new data from 17,000 patients that suggested 82% had a mild form of the disease, with 15% considered severe cases & 3% critical. 2/14/2020 Biplov Thapa, Health Assistant 17
  • 18. What do you think 2019 nCoV & Flu are same ? 2/14/2020 Biplov Thapa, Health Assistant 18 Uh.. Uh
  • 19. How can we prevent 2019 nCoV Infection ? 2/14/2020 Biplov Thapa, Health Assistant 19
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  • 27. Top questions that are asked during WHO press conference on“2019 nCoV” 2/14/2020 Biplov Thapa, Health Assistant 27
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  • 36. Effort by GoN to address 2019 Novel Corona Virus Epidemic: 1. Awareness program 2. Establishment of “Help Desk” 3. “Rapid Response Team” 4. Hospital with “Isolation Bed” for suspected cases 5. Diagnostic laboratory services etc. 2/14/2020 Biplov Thapa, Health Assistant 36
  • 38. References: WHO officials posts (www.who.int) CDC officials articles (www.cdc.gov) BBC News (www.bbc.com) Chinese Newspaper posts & articles Epidemiology & Disease Control Division, GoN 2/14/2020 Biplov Thapa, Health Assistant 38
  • 39. Don’t you have any quires ? 2/14/2020 Biplov Thapa, Health Assistant 39
  • 40. 2/14/2020 Biplov Thapa, Health Assistant 40 “Stay Safe & Stay Healthy” Bye Bye …... Have a Good day