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Attribution: https://pixabay.com/photos/tire-rim-car-mechanic-114259/
Focus on Indication, Product, Biomarker,
and Region
Analysis and Forecast: 2021-2031
March 2022
Radioligand
Therapy Market -
A Global and
Regional Analysis
Table of Content
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BIS Research is a leading market intelligence and technology research company. BIS Research publishes in-
depth market intelligence reports focusing on the market estimations, technology analysis, emerging high-
growth applications, deeply segmented granular country-level market data and other important market
parameters useful in the strategic decision making for senior management. BIS Research provides multi-client
reports, company profiles, databases, and custom research services.
Copyright © 2022 BIS Research Inc.
All Rights Reserved. This document contains highly confidential information and is the sole property of BIS
Research. Disclosing, copying, circulating, quoting, or otherwise reproducing any or all contents of this
document is strictly prohibited. Access to this information is provided exclusively for the benefit of the people
or organization concerned. It may not be accessed by or offered whether for sale or otherwise to any third
party.
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Table of Content
Executive Summary..........................................................................19
1. Research Methodology ..............................................................25
1.1 Radioligand Therapy: Research Methodology..............................................25
1.2 Primary Data Sources .....................................................................................26
1.3 Secondary Data Sources ................................................................................26
1.4 Market Estimation Model.................................................................................27
1.5 Criteria for Company Profiling........................................................................29
2. Radioligand Therapy Market ......................................................30
2.1 Product Definition............................................................................................31
2.1.1 Inclusion and Exclusion .............................................................................31
2.2 Market Scope ...................................................................................................31
2.2.1 Scope of the Study......................................................................................31
2.2.2 Key Questions Answered in the Report ....................................................32
2.3 Market Overview ..............................................................................................33
2.3.1 Market Definition .........................................................................................33
2.3.2 Emerging Applications of Radioligand Therapy.......................................33
2.3.2.1 Neuroendocrine Neoplasms .................................................................................. 34
2.3.2.2 Prostate Cancer..................................................................................................... 35
2.3.2.3 Non-Cancerous Condition ..................................................................................... 35
2.3.3 Market Footprint and Growth Potential .....................................................36
2.3.4 COVID-19 Impact on Global Radioligand Therapy Market .......................36
2.3.4.1 Impact on Radioligand Therapy............................................................................. 36
2.3.4.2 Clinical Trial Disruptions and Resumptions ........................................................... 37
3. Industry Analysis .......................................................................38
3.1 Overview...........................................................................................................39
3.2 Challenges in Radioligand Therapy Regulatory Approval Pathway ...........39
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3.3 Regulatory Scenario of Radioligand Therapy ...............................................39
3.4 Legal Requirements and Frameworks in the U.S..........................................41
3.4.1 Clinical Trial Authorization .........................................................................41
3.4.2 Marketing Authorization .............................................................................41
3.4.3 U.S. FDA Guidelines for NDA Submission ................................................42
3.4.4 Post-Authorization Regulations.................................................................43
3.5 Legal Requirements and Frameworks in Europe..........................................44
3.5.1 EMA Drug License Application Process ...................................................45
3.5.2 Centralized Procedure ................................................................................46
3.5.3 Decentralized Procedure ............................................................................46
3.5.4 Mutual-Recognition Procedure ..................................................................46
3.5.5 National Procedure......................................................................................46
3.6 Legal Requirements and Frameworks in Asia-Pacific..................................46
3.6.1 Legal Requirements and Frameworks in Japan .......................................46
4. Pipeline Analysis........................................................................48
4.1 Radioligand Therapy Pipeline Analysis.........................................................49
4.2 Radioligand Therapy Clinical Trial Design ....................................................51
4.2.1 [Lu-177]-PNT2002 ........................................................................................51
4.2.1.1 Product Profile....................................................................................................... 51
4.2.1.2 [Lu-177]-PNT2002 Phase III Study Design ........................................................... 52
4.2.1.3 [Lu-177]-PNT2002 Efficacy, Safety, and Tolerability (Phase II) ............................ 54
4.2.1.4 177Lu-PNT2002 Pharmacokinetics and Pharmacodynamics Profile (Phase I)..... 55
4.2.2 CAM H2.........................................................................................................55
4.2.2.1 Product Profile....................................................................................................... 55
4.2.2.2 CAM H2 Preclinical Study Design ......................................................................... 56
4.2.2.3 CAM H2 Phase I/IIa Clinical Study Design............................................................ 56
4.2.3 [177Lu]-NeoB ...............................................................................................57
4.2.3.1 Product Profile....................................................................................................... 57
4.2.3.2 (177Lu)-NeoB Preclinical Studies.......................................................................... 57
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4.2.3.3 (177Lu)-NeoB Phase I/II Clinical Study Design..................................................... 58
4.2.4 PNT-2003......................................................................................................59
4.2.4.1 Product Profile....................................................................................................... 59
4.2.4.2 PNT 2003 Ongoing Phase III Clinical Study Design.............................................. 59
4.2.5 ITM-11...........................................................................................................60
4.2.5.1 Product Profile....................................................................................................... 60
4.2.5.2 ITM-11 Preclinical Proof-of-Concept Studies ........................................................ 61
4.2.5.3 ITM-11 Phase III Clinical Trial Design ................................................................... 61
4.2.6 177.Lu FAP-2286..........................................................................................62
4.2.6.1 Product Profile....................................................................................................... 62
4.2.6.2 177.Lu FAP, 2286 Preclinical Study Summary...................................................... 62
4.2.6.3 177Lu-FAP-2286 Phase I/IIa Clinical Study Design .............................................. 62
4.2.7 FPI-1434........................................................................................................63
4.2.7.1 Product Profile....................................................................................................... 63
4.2.7.2 FPI-1434 Preclinical Study Summary.................................................................... 63
4.2.7.3 FPI-1434 Phase I/IIa Clinical Study Design........................................................... 63
4.2.8 FPI-1966........................................................................................................64
4.2.8.1 Product Profile....................................................................................................... 64
4.2.8.2 FPI-1966 Preclinical Study Summary.................................................................... 64
4.2.9 177Lu-DOTA-rosopatamab .........................................................................65
4.2.9.1 Product Profile....................................................................................................... 65
4.2.9.2 TLX591 (177Lu-DOTA-rosopatamab) Ongoing Phase III Clinical Study
Design ................................................................................................................... 65
5. Market Dynamics .......................................................................67
5.1 Overview...........................................................................................................68
5.2 Impact Analysis ...............................................................................................68
5.3 Market Drivers..................................................................................................69
5.3.1 Radioligand Therapy Demand Inclined by Rising Prevalence of
Cancer.................................................................................................69
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5.3.2 Strategic Initiatives by Key Market Players...............................................70
5.3.3 Rise in Clinical Research Activity..............................................................71
5.4 Market Restraints.............................................................................................71
5.4.1 High Cost Associated with Treatment and Complex Reimbursement
Processes ...........................................................................................71
5.4.2 Increased Competition from Generics.......................................................72
5.5 Market Opportunities.......................................................................................72
5.5.1 Expanding Radiopharmaceutical Coverage..............................................72
5.5.2 Role of Radioligand in Drug Discovery .....................................................73
6. Competitive Landscape .............................................................74
6.1 Overview...........................................................................................................75
6.2 Product Launch ...............................................................................................75
6.3 Product Approvals...........................................................................................76
6.4 Synergistic Activities ......................................................................................77
6.5 Mergers and Acquisitions...............................................................................77
6.6 Market Share Analysis (by Company), 2020..................................................78
7. Global Radioligand Therapy Market, Indication, $Million, 2020-
2031 ..........................................................................................79
7.1 Overview...........................................................................................................80
7.2 Prostate Cancer ...............................................................................................81
7.3 Neuroendocrine Tumor (NETs).......................................................................82
7.4 Other.................................................................................................................83
8. Global Radioligand Therapy Market, Products, $Million, 2020-
2031 ..........................................................................................84
8.1 Overview...........................................................................................................85
8.2 Approved Products .........................................................................................85
8.2.1 Lutathera......................................................................................................86
8.2.2 Zytiga............................................................................................................87
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8.2.3 Xtandi ...........................................................................................................88
8.2.4 Xofigo ...........................................................................................................89
8.3 Potential Pipeline.............................................................................................90
9. Global Radioligand Therapy Market, Biomarker, $Million,
2020-2031..................................................................................93
9.1 Overview...........................................................................................................94
9.2 Prostate-Specific Membrane Antigen ............................................................95
9.3 Ki 67 Expression and Grading........................................................................96
9.4 Cytochrome P450 17A1 Inhibitor....................................................................97
10. Global Radioligand Therapy Market, Region, $Million, 2020-
2031 ..........................................................................................99
10.1 Overview.........................................................................................................100
10.2 North America................................................................................................103
10.2.1 U.S........................................................................................................105
10.2.2 Canada.................................................................................................106
10.3 Europe ............................................................................................................108
10.3.1 Germany ..............................................................................................109
10.3.2 France ..................................................................................................110
10.3.3 U.K........................................................................................................111
10.3.4 Italy.......................................................................................................112
10.3.5 Spain ....................................................................................................113
10.3.6 Rest-of-Europe ....................................................................................114
10.4 Asia-Pacific ....................................................................................................115
10.4.1 Japan....................................................................................................117
10.4.2 South Korea.........................................................................................118
10.4.3 Australia...............................................................................................119
10.4.4 Rest-of-Asia-Pacific (RoAPAC)..........................................................120
10.5 Rest-of-the-World (RoW)...............................................................................121
11. Markets - Competitive Benchmarking & Company Profiles ......122
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11.1 Overview.........................................................................................................123
11.2 Johnson & Johnson Services, Inc. ..............................................................124
11.2.1 Company Overview.............................................................................124
11.2.2 Role of Johnson & Johnson Services, Inc. in the Global
Radioligand Therapy Market ...........................................................124
11.2.3 Product ASP (by Region) ...................................................................125
11.2.4 Key Competitors of Company............................................................125
11.2.5 Financials ............................................................................................126
11.2.6 Key Insights About the Financial Health of the Company...............128
11.2.7 SWOT Analysis....................................................................................129
11.3 Pfizer Inc.........................................................................................................130
11.3.1 Company Overview.............................................................................130
11.3.2 Role of Pfizer Inc. in the Global Radioligand Therapy Market.........130
11.3.3 Product ASP (by Region) ...................................................................130
11.3.4 Key Competitors of Company............................................................131
11.3.5 Financials ............................................................................................132
11.3.6 Key Insights About Financial Health of the Company.....................133
11.3.7 Business Strategies............................................................................133
11.3.7.1 Product Approval ............................................................................................. 133
11.3.8 SWOT Analysis....................................................................................134
11.4 Amneal Pharmaceuticals LLC. .....................................................................135
11.4.1 Company Overview.............................................................................135
11.4.2 Role of Amneal Pharmaceuticals LLC. in the Global Radioligand
Therapy Market.................................................................................135
11.4.3 Key Competitors of Company............................................................135
11.4.4 Financials ............................................................................................136
11.4.5 Key Insights About Financial Health of the Company .....................137
11.4.6 Business Strategies............................................................................138
11.4.6.1 Product Launch................................................................................................ 138
11.4.7 SWOT Analysis....................................................................................138
11.5 Novartis International AG..............................................................................139
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11.5.1 Company Overview.............................................................................139
11.5.2 Role of Novartis International AG in the Global Radioligand
Therapy Market.................................................................................139
11.5.3 Product ASP (by Region) ...................................................................139
11.5.4 Key Competitors of Company............................................................140
11.5.5 Financials ............................................................................................141
11.5.6 Key Insights About Financial Health of the Company .....................142
11.5.7 Corporate Strategies...........................................................................143
11.5.7.1 Mergers and Acquisitions ................................................................................ 143
11.5.7.2 Synergistic Activities........................................................................................ 143
11.5.7.3 Business Expansion and Funding ................................................................... 143
11.5.8 Business Strategies............................................................................143
11.5.8.1 Product Launches and Approval...................................................................... 144
11.5.9 SWOT Analysis....................................................................................145
11.6 POINT Biopharma Global Inc........................................................................146
11.6.1 Company Overview.............................................................................146
11.6.2 Role of POINT Biopharma Global Inc in the Global Radioligand
Therapy Market.................................................................................146
11.6.3 Key Competitors of Company............................................................146
11.6.4 Corporate Strategies...........................................................................147
11.6.5 SWOT Analysis....................................................................................148
11.7 Fusion Pharma...............................................................................................149
11.7.1 Company Overview.............................................................................149
11.7.2 Role of Fusion Pharma in the Global Radioligand Therapy
Market ...............................................................................................149
11.7.3 Key Competitors of Company............................................................149
11.7.4 Financials ............................................................................................150
11.7.5 Key Insights About the Financial Health of the Company...............151
11.7.6 Corporate Strategies...........................................................................151
11.7.6.1 Synergistic Activities........................................................................................ 151
11.7.7 SWOT Analysis....................................................................................152
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11.8 Clovis Oncology ............................................................................................153
11.8.1 Company Overview.............................................................................153
11.8.2 Role of Clovis Oncology in the Global Radioligand Therapy
Market ...............................................................................................153
11.8.3 Key Competitors of Company............................................................153
11.8.4 Financials ............................................................................................154
11.8.5 Key Insights About the Financial Health of the Company...............155
11.8.6 Corporate Strategies...........................................................................156
11.8.6.1 Mergers and Acquisitions ................................................................................ 156
11.8.7 SWOT Analysis....................................................................................156
11.9 Telix Pharmaceuticals ...................................................................................157
11.9.1 Company Overview.............................................................................157
11.9.2 Role of Telix Pharmaceuticals in the Global Radioligand
Therapy Market.................................................................................157
11.9.3 Key Competitors of Company............................................................157
11.9.4 Financials ............................................................................................158
11.9.5 Key Insights About the Financial Health of the Company...............159
11.9.6 Corporate Strategies...........................................................................159
11.9.6.1 Mergers and Acquisitions ................................................................................ 159
11.9.6.2 Synergistic Activities........................................................................................ 159
11.9.7 SWOT Analysis....................................................................................160
11.10 Lantheus Holdings, Inc. (Progenics Pharmaceuticals) ..............................161
11.10.1 Company Overview.............................................................................161
11.10.2 Role of Lantheus Holdings Inc., (Progenics Pharmaceuticals) in
the Global Radioligand Therapy Market.........................................161
11.10.3 Key Competitors of Company............................................................161
11.10.4 Financials ............................................................................................162
11.10.5 Key Insights About the Financial Health of the Company...............164
11.10.6 Corporate Strategies...........................................................................164
11.10.6.1 Mergers and Acquisitions ................................................................................ 164
11.10.7 SWOT Analysis....................................................................................165
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11.11 Bayer AG ........................................................................................................166
11.11.1 Company Overview.............................................................................166
11.11.2 Role of Bayer AG in the Global Radioligand Therapy Market .........166
11.11.3 Product ASP (by Region) ...................................................................166
11.11.4 Key Competitors of Company............................................................166
11.11.5 Financials ............................................................................................167
11.11.6 Key Insights About the Financial Health of the Company...............168
11.11.7 Corporate Strategies...........................................................................169
11.11.7.1 Mergers and Acquisitions ................................................................................ 169
11.11.7.2 Product Approval ............................................................................................. 169
11.11.8 SWOT Analysis....................................................................................169
11.12 Molecular Partners ........................................................................................170
11.12.1 Company Overview.............................................................................170
11.12.2 Role of Molecular Partners in the Global Radioligand Therapy
Market ...............................................................................................170
11.12.3 Key Competitors of Company............................................................170
11.12.4 SWOT Analysis....................................................................................171
12. Emerging Company Profiles.....................................................172
12.1 ITM Isotope Technologies Munich SE .........................................................172
12.1.1 Company Overview.............................................................................172
12.1.2 Role of ITM Isotope Technologies Munich SE in the Global
Radioligand Therapy Market ...........................................................172
12.1.3 Key Competitors of Company............................................................172
12.1.4 SWOT Analysis....................................................................................173
12.2 Curium Pharma..............................................................................................174
12.2.1 Company Overview.............................................................................174
12.2.2 Role of Curium Pharma. in the Global Radioligand Therapy
Market ...............................................................................................174
12.2.3 Key Competitors of Company............................................................174
12.2.4 SWOT Analysis....................................................................................175
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12.3 Precirix ...........................................................................................................176
12.3.1 Company Overview.............................................................................176
12.3.2 Role of Precirix in the Global Radioligand Therapy Market ............176
12.3.3 Key Competitors of Company............................................................176
12.3.4 SWOT Analysis....................................................................................177
12.4 Radio Medix....................................................................................................178
12.4.1 Company Overview.............................................................................178
12.4.2 Role of Radio Medix in the Global Radioligand Therapy Market ....178
12.4.3 Key Competitors of Company............................................................178
12.4.4 SWOT Analysis....................................................................................179
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List of Figures
Figure 1: Global Cancer Burden, 2020
Figure 2: Impact Analysis of Market Drivers and Market Challenges on the Global Radioligand
Therapy Market
Figure 3: Revenue Contribution of Different Segments, 2020, 2029, and 2031
Figure 4: Revenue Contribution of Different Segments, 2020, 2021, and 2031
Figure 5: Revenue Contribution of Different Segments, 2020, 2021, and 2031
Figure 6: Global Radioligand Therapy Market (by Region), $Million, 2023-2031
Figure 7: Global Radioligand Therapy Methodology
Figure 8: Primary Research Methodology
Figure 9: Epidemiology-Based Approach
Figure 10: Global Radioligand Therapy Market Segmentation
Figure 11: Global Radioligand Therapy Market, $Million, 2020-2031
Figure 12: Clinical Trial Authorization for Radioligand Therapy in the U.S.
Figure 13: Steps for Obtaining Marketing Authorization
Figure 14: U.S. FDA Review Timeline
Figure 15: EMA Review Timeline
Figure 16: Radioligand Therapy Global Clinical Trials (by Phase), 2021
Figure 17: Radioligand Therapy Global Clinical Trials 2021
Figure 18: 177Lu-PSMA-617 (RA101495) Mechanism of Action
Figure 19: [Lu-177]-PNT2002 Phase III Clinical Trial Design for Metastatic Castration-Resistant
Prostate Cancer
Figure 20: 177Lu-PNT2002 Phase II Clinical Trial Design for Metastatic Castration-Resistant Prostate
Cancer
Figure 21: 177Lu-PNT2002 PK/PD Profile Results
Figure 22: CAM H2 Phase I Portion Clinical Study
Figure 23: Solid Tumors with Overexpression
Figure 24: (177Lu)-NeoB Preclinical Studies Framework
Figure 25: (177Lu)-NeoB Phase I Portion Clinical Study
Figure 26: Phase III clinical Design for PNT-2003
Figure 27: Results from ITM-11 Phase III Clinical Trial
Figure 28: 177Lu-FAP-2286 I/IIa Portion Clinical Study
Figure 29: FPI-1434 I/IIa Portion Clinical Study
Figure 30: Phase III clinical Design for PNT-2003
Figure 31: Global Cancer Burden, 2020
Figure 32: Share of Key Developments, January 2018-February 2022
Figure 33: Share of Product Approvals (by Company), January 2018-November 2021
Figure 34: Share of Synergistic Activities (by Company), January 2018-February 2022
Figure 35: Share of Mergers and Acquisitions (by Company), January 2018-February 2022
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Figure 36: Market Share Analysis of Global Radio Ligand Therapy Market (by Company), 2020
Figure 37: Revenue Contribution of Different Segments, 2020, 2039, and 2031
Figure 38: Global Radioligand Therapy Market (Prostate Cancer), $Million, 2020-2031
Figure 39: Global Radioligand Therapy Market (Neuroendocrine Tumors), $Million, 2025-2031
Figure 40: Global Radioligand Therapy Market (Others), $Million, 2029-2031
Figure 41: Global Radioligand Therapy Market Segmentation (by Product)
Figure 42: Global Radioligand Therapy Market (Approved Products), $Million, 2020-2031
Figure 43: Global Radioligand Therapy Market (Lutathera), $Million, 2020-2031
Figure 44: Global Radioligand Therapy Market (Zytiga), $Million, 2020-2031
Figure 45: Global Radioligand Therapy Market (Xtandi), $Million, 2020-2031
Figure 46: Global Radioligand Therapy Market (Xofigo), $Million, 2020-2031
Figure 47: Global Radioligand Therapy Market (Potential Pipeline), $Million, 2024-2031
Figure 48: Global Radioligand Therapy Market (by Potential Pipeline Drugs (Phase 3)), $Million, 2024-
2031
Figure 49: Global Radioligand Therapy Market (by Potential Pipeline Drugs (Phase 2)), $Million, 2029-
2031
Figure 50: Global Radioligand Therapy Market (by Biomarker)
Figure 51: Global Radioligand Therapy Market (by Biomarker), $Million, 2020 and 2031
Figure 52: Global Radioligand Therapy Market (Prostate-Specific Membrane Antigen), $Million, 2020-
2031
Figure 53: Global Radioligand Therapy Market (Ki 67 Expression and Grading), $Million, 2020-2031
Figure 54: Global Radioligand Therapy Market (Cytochrome P450 17A1 Inhibitor), $Million, 2020-2031
Figure 55: Global Radioligand Therapy Market Snapshot (by Region), $Million, 2020-2031
Figure 56: Global Radioligand Therapy Market (by Region), $Million, 2020-2031
Figure 57: North America Radioligand Therapy Market, $Million, 2020-2031
Figure 58: North America: Market Dynamics
Figure 59: North America Radioligand Therapy Market (by Country), $Million, 2020-2031
Figure 60: U.S. Radioligand Therapy Market, $Million, 2020-2031
Figure 61: Canada Radioligand Therapy Market, $Million, 2020-2031
Figure 62: Europe Radioligand Therapy Market, $Million, 2020-2031
Figure 63: Europe: Market Dynamics
Figure 64: Europe Radioligand Therapy Market (by Country), $Million, 2020-2031
Figure 65: Germany Radioligand Therapy Market, $Million, 2020-2031
Figure 66: France Radioligand Therapy Market, $Million, 2020-2031
Figure 67: U.K. Radioligand Therapy Market, $Million, 2020-2031
Figure 68: Italy Radioligand Therapy Market, $Million, 2020-2031
Figure 69: Spain Radioligand Therapy Market, $Million, 2020-2031
Figure 70: Rest-of Europe Radioligand Therapy Market, $Million, 2020-2031
Figure 71: Asia-Pacific Radioligand Therapy Market, $Million, 2020-2031
Figure 72: Asia-Pacific: Market Dynamics
Figure 73: APAC Radioligand Therapy Market (by Country), $Million, 2020-2031
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Figure 74: Japan Radioligand Therapy Market, $Million, 2020-2031
Figure 75: South Korea Radioligand Therapy Market, $Million, 2020-2031
Figure 76: Australia Radioligand Therapy Market, $Million, 2020-2031
Figure 77: RoAPAC Radioligand Therapy Market, $Million, 2020-2031
Figure 78: Rest-of-the-World (RoW) Radioligand Therapy Market, $Million, 2020-2031
Figure 79: Total Number of Companies Profiled
Figure 80: Johnson & Johnson Services, Inc.: Product Portfolio
Figure 81: Johnson & Johnson Services, Inc.: Overall Financials, $Million, 2018-2020
Figure 82: Johnson & Johnson Services, Inc.: Revenue (by Segment), $Million, 2018-2020
Figure 83: Johnson & Johnson Services, Inc.: Revenue (by Region), $Million, 2018-2020
Figure 84: Johnson & Johnson Services, Inc.: R&D Expenditure, $Million, 2018-2020
Figure 85: Johnson & Johnson Services, Inc.: SWOT Analysis
Figure 86: Pfizer Inc.: Commercialized Therapy
Figure 87: Pfizer Inc.: Overall Financials, $Million, 2018-2020
Figure 88: Pfizer Inc.: Revenue (by Region), $Million, 2018-2020
Figure 89: Pfizer Inc.: R&D Expenditure, $Million, 2018-2020
Figure 90: Pfizer Inc.: SWOT Analysis
Figure 91: Amneal Pharmaceuticals LLC.: Commercialized Therapy
Figure 92: Amneal Pharmaceuticals LLC.: Overall Financials, $Million, 2018-2020
Figure 93: Amneal Pharmaceuticals LLC.: Revenue (by Segment), $Million, 2018-2020
Figure 94: Amneal Pharmaceuticals LLC.: R&D Expenditure, $Million, 2018-2020
Figure 95: Amneal Pharmaceuticals.: SWOT Analysis
Figure 96: Novartis International AG: Commercialized Therapy
Figure 97: Novartis International AG: Pre-Clinical and Clinical Assets
Figure 98: Novartis International AG: Overall Financials, $Million, 2018-2020
Figure 99: Novartis International AG: Revenue (by Segment), $Million, 2018-2020
Figure 100: Novartis International AG: Revenue (by Region), $Million, 2018-2020
Figure 101: Novartis International AG: R&D Expenditure, $Million, 2018-2020
Figure 102: Novartis International AG: SWOT Analysis
Figure 103: POINT Biopharma Global Inc.: Pipeline Therapy
Figure 104: POINT Biopharma Global Inc.: SWOT Analysis
Figure 105: Fusion Pharma: Pipeline Portfolio
Figure 106: Fusion Pharma: Overall Financials, $Million, 2019-2020
Figure 107: Fusion Pharma: R&D Expenditure, $Million, 2019-2020
Figure 108: Fusion Pharma: SWOT Analysis
Figure 109: Clovis Oncology.: Pipeline Portfolio
Figure 110: Clovis Oncology.: Overall Financials, $Million, 2018-2020
Figure 111: Clovis Oncology.: Revenue (by Region), $Million, 2019-2020
Figure 112: Clovis Oncology.: R&D Expenditure, $Million, 2018-2020
Figure 113: Clovis Oncology.: SWOT Analysis
16
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Figure 114: Telix Pharmaceuticals: Product Portfolio
Figure 115: Telix Pharmaceuticals: Overall Financials, $Million, 2018-2020
Figure 116: Telix Pharmaceuticals: R&D Expenditure, $Million, 2018-2020
Figure 117: Telix Pharmaceuticals.: SWOT Analysis
Figure 118: Lantheus Holdings Inc., (Progenics Pharmaceuticals): Pipeline Portfolio
Figure 119: Lantheus Holdings Inc. (Progenics Pharmaceuticals): Overall Financials, $Million, 2018-
2020
Figure 120: Lantheus Holdings Inc. (Progenics Pharmaceuticals): Revenue (by Segment), $Million,
2019 and 2020
Figure 121: Lantheus Holdings Inc. (Progenics Pharmaceuticals): Revenue (by Region), $Million,
2018-2020
Figure 122: Lantheus Holdings Inc. (Progenics Pharmaceuticals): R&D Expenditure, $Million, 2018-
2020
Figure 123: Lantheus Holdings Inc. (Progenics Pharmaceuticals): SWOT Analysis
Figure 124: Bayer AG.: Product Portfolio
Figure 125: Bayer AG.: Overall Financials, $Million, 2018-2020
Figure 126: Bayer AG: Revenue (by Region), $Million, 2018-2020
Figure 127: Bayer AG.: R&D Expenditure, $Million, 2018-2020
Figure 128: Bayer AG.: SWOT Analysis
Figure 129: Molecular Partners.: Product Portfolio
Figure 130: Molecular Partners.: SWOT Analysis
Figure 131: ITM Isotope Technologies Munich SE: Product Portfolio
Figure 132: ITM Isotope Technologies Munich SE: SWOT Analysis
Figure 133: Curium Pharma.: Product Portfolio
Figure 134: Curium Pharma: SWOT Analysis
Figure 135: Precirix: Product Portfolio
Figure 136: Precirix: SWOT Analysis
Figure 137: Radiomedix: Product Portfolio
Figure 138: RadioMedix: SWOT Analysis
17
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List of Tables
Table 1: Regulatory Scenario of Radioligand Therapy
Table 2: Emerging Radioligand Therapy Pipeline
Table 3: Likert Scale
Table 4: Impact Analysis of Market Drivers
Table 5: Impact Analysis of Market Restraints
Table 6: Lutathera ASP by Region
Table 7: Xtandi: Indications
18
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Radioligand Therapy Market

  • 1. 1 All rights reserved at BIS Research Inc. R a d i o l i g a n d T h e r a p y M a r k e t res Attribution: https://pixabay.com/photos/tire-rim-car-mechanic-114259/ Focus on Indication, Product, Biomarker, and Region Analysis and Forecast: 2021-2031 March 2022 Radioligand Therapy Market - A Global and Regional Analysis Table of Content
  • 2. 2 All rights reserved at BIS Research Inc. R a d i o l i g a n d T h e r a p y M a r k e t BIS Research is a leading market intelligence and technology research company. BIS Research publishes in- depth market intelligence reports focusing on the market estimations, technology analysis, emerging high- growth applications, deeply segmented granular country-level market data and other important market parameters useful in the strategic decision making for senior management. BIS Research provides multi-client reports, company profiles, databases, and custom research services. Copyright © 2022 BIS Research Inc. All Rights Reserved. This document contains highly confidential information and is the sole property of BIS Research. Disclosing, copying, circulating, quoting, or otherwise reproducing any or all contents of this document is strictly prohibited. Access to this information is provided exclusively for the benefit of the people or organization concerned. It may not be accessed by or offered whether for sale or otherwise to any third party.
  • 3. 3 All rights reserved at BIS Research Inc. R a d i o l i g a n d T h e r a p y M a r k e t Table of Content Executive Summary..........................................................................19 1. Research Methodology ..............................................................25 1.1 Radioligand Therapy: Research Methodology..............................................25 1.2 Primary Data Sources .....................................................................................26 1.3 Secondary Data Sources ................................................................................26 1.4 Market Estimation Model.................................................................................27 1.5 Criteria for Company Profiling........................................................................29 2. Radioligand Therapy Market ......................................................30 2.1 Product Definition............................................................................................31 2.1.1 Inclusion and Exclusion .............................................................................31 2.2 Market Scope ...................................................................................................31 2.2.1 Scope of the Study......................................................................................31 2.2.2 Key Questions Answered in the Report ....................................................32 2.3 Market Overview ..............................................................................................33 2.3.1 Market Definition .........................................................................................33 2.3.2 Emerging Applications of Radioligand Therapy.......................................33 2.3.2.1 Neuroendocrine Neoplasms .................................................................................. 34 2.3.2.2 Prostate Cancer..................................................................................................... 35 2.3.2.3 Non-Cancerous Condition ..................................................................................... 35 2.3.3 Market Footprint and Growth Potential .....................................................36 2.3.4 COVID-19 Impact on Global Radioligand Therapy Market .......................36 2.3.4.1 Impact on Radioligand Therapy............................................................................. 36 2.3.4.2 Clinical Trial Disruptions and Resumptions ........................................................... 37 3. Industry Analysis .......................................................................38 3.1 Overview...........................................................................................................39 3.2 Challenges in Radioligand Therapy Regulatory Approval Pathway ...........39
  • 4. 4 All rights reserved at BIS Research Inc. R a d i o l i g a n d T h e r a p y M a r k e t 3.3 Regulatory Scenario of Radioligand Therapy ...............................................39 3.4 Legal Requirements and Frameworks in the U.S..........................................41 3.4.1 Clinical Trial Authorization .........................................................................41 3.4.2 Marketing Authorization .............................................................................41 3.4.3 U.S. FDA Guidelines for NDA Submission ................................................42 3.4.4 Post-Authorization Regulations.................................................................43 3.5 Legal Requirements and Frameworks in Europe..........................................44 3.5.1 EMA Drug License Application Process ...................................................45 3.5.2 Centralized Procedure ................................................................................46 3.5.3 Decentralized Procedure ............................................................................46 3.5.4 Mutual-Recognition Procedure ..................................................................46 3.5.5 National Procedure......................................................................................46 3.6 Legal Requirements and Frameworks in Asia-Pacific..................................46 3.6.1 Legal Requirements and Frameworks in Japan .......................................46 4. Pipeline Analysis........................................................................48 4.1 Radioligand Therapy Pipeline Analysis.........................................................49 4.2 Radioligand Therapy Clinical Trial Design ....................................................51 4.2.1 [Lu-177]-PNT2002 ........................................................................................51 4.2.1.1 Product Profile....................................................................................................... 51 4.2.1.2 [Lu-177]-PNT2002 Phase III Study Design ........................................................... 52 4.2.1.3 [Lu-177]-PNT2002 Efficacy, Safety, and Tolerability (Phase II) ............................ 54 4.2.1.4 177Lu-PNT2002 Pharmacokinetics and Pharmacodynamics Profile (Phase I)..... 55 4.2.2 CAM H2.........................................................................................................55 4.2.2.1 Product Profile....................................................................................................... 55 4.2.2.2 CAM H2 Preclinical Study Design ......................................................................... 56 4.2.2.3 CAM H2 Phase I/IIa Clinical Study Design............................................................ 56 4.2.3 [177Lu]-NeoB ...............................................................................................57 4.2.3.1 Product Profile....................................................................................................... 57 4.2.3.2 (177Lu)-NeoB Preclinical Studies.......................................................................... 57
  • 5. 5 All rights reserved at BIS Research Inc. R a d i o l i g a n d T h e r a p y M a r k e t 4.2.3.3 (177Lu)-NeoB Phase I/II Clinical Study Design..................................................... 58 4.2.4 PNT-2003......................................................................................................59 4.2.4.1 Product Profile....................................................................................................... 59 4.2.4.2 PNT 2003 Ongoing Phase III Clinical Study Design.............................................. 59 4.2.5 ITM-11...........................................................................................................60 4.2.5.1 Product Profile....................................................................................................... 60 4.2.5.2 ITM-11 Preclinical Proof-of-Concept Studies ........................................................ 61 4.2.5.3 ITM-11 Phase III Clinical Trial Design ................................................................... 61 4.2.6 177.Lu FAP-2286..........................................................................................62 4.2.6.1 Product Profile....................................................................................................... 62 4.2.6.2 177.Lu FAP, 2286 Preclinical Study Summary...................................................... 62 4.2.6.3 177Lu-FAP-2286 Phase I/IIa Clinical Study Design .............................................. 62 4.2.7 FPI-1434........................................................................................................63 4.2.7.1 Product Profile....................................................................................................... 63 4.2.7.2 FPI-1434 Preclinical Study Summary.................................................................... 63 4.2.7.3 FPI-1434 Phase I/IIa Clinical Study Design........................................................... 63 4.2.8 FPI-1966........................................................................................................64 4.2.8.1 Product Profile....................................................................................................... 64 4.2.8.2 FPI-1966 Preclinical Study Summary.................................................................... 64 4.2.9 177Lu-DOTA-rosopatamab .........................................................................65 4.2.9.1 Product Profile....................................................................................................... 65 4.2.9.2 TLX591 (177Lu-DOTA-rosopatamab) Ongoing Phase III Clinical Study Design ................................................................................................................... 65 5. Market Dynamics .......................................................................67 5.1 Overview...........................................................................................................68 5.2 Impact Analysis ...............................................................................................68 5.3 Market Drivers..................................................................................................69 5.3.1 Radioligand Therapy Demand Inclined by Rising Prevalence of Cancer.................................................................................................69
  • 6. 6 All rights reserved at BIS Research Inc. R a d i o l i g a n d T h e r a p y M a r k e t 5.3.2 Strategic Initiatives by Key Market Players...............................................70 5.3.3 Rise in Clinical Research Activity..............................................................71 5.4 Market Restraints.............................................................................................71 5.4.1 High Cost Associated with Treatment and Complex Reimbursement Processes ...........................................................................................71 5.4.2 Increased Competition from Generics.......................................................72 5.5 Market Opportunities.......................................................................................72 5.5.1 Expanding Radiopharmaceutical Coverage..............................................72 5.5.2 Role of Radioligand in Drug Discovery .....................................................73 6. Competitive Landscape .............................................................74 6.1 Overview...........................................................................................................75 6.2 Product Launch ...............................................................................................75 6.3 Product Approvals...........................................................................................76 6.4 Synergistic Activities ......................................................................................77 6.5 Mergers and Acquisitions...............................................................................77 6.6 Market Share Analysis (by Company), 2020..................................................78 7. Global Radioligand Therapy Market, Indication, $Million, 2020- 2031 ..........................................................................................79 7.1 Overview...........................................................................................................80 7.2 Prostate Cancer ...............................................................................................81 7.3 Neuroendocrine Tumor (NETs).......................................................................82 7.4 Other.................................................................................................................83 8. Global Radioligand Therapy Market, Products, $Million, 2020- 2031 ..........................................................................................84 8.1 Overview...........................................................................................................85 8.2 Approved Products .........................................................................................85 8.2.1 Lutathera......................................................................................................86 8.2.2 Zytiga............................................................................................................87
  • 7. 7 All rights reserved at BIS Research Inc. R a d i o l i g a n d T h e r a p y M a r k e t 8.2.3 Xtandi ...........................................................................................................88 8.2.4 Xofigo ...........................................................................................................89 8.3 Potential Pipeline.............................................................................................90 9. Global Radioligand Therapy Market, Biomarker, $Million, 2020-2031..................................................................................93 9.1 Overview...........................................................................................................94 9.2 Prostate-Specific Membrane Antigen ............................................................95 9.3 Ki 67 Expression and Grading........................................................................96 9.4 Cytochrome P450 17A1 Inhibitor....................................................................97 10. Global Radioligand Therapy Market, Region, $Million, 2020- 2031 ..........................................................................................99 10.1 Overview.........................................................................................................100 10.2 North America................................................................................................103 10.2.1 U.S........................................................................................................105 10.2.2 Canada.................................................................................................106 10.3 Europe ............................................................................................................108 10.3.1 Germany ..............................................................................................109 10.3.2 France ..................................................................................................110 10.3.3 U.K........................................................................................................111 10.3.4 Italy.......................................................................................................112 10.3.5 Spain ....................................................................................................113 10.3.6 Rest-of-Europe ....................................................................................114 10.4 Asia-Pacific ....................................................................................................115 10.4.1 Japan....................................................................................................117 10.4.2 South Korea.........................................................................................118 10.4.3 Australia...............................................................................................119 10.4.4 Rest-of-Asia-Pacific (RoAPAC)..........................................................120 10.5 Rest-of-the-World (RoW)...............................................................................121 11. Markets - Competitive Benchmarking & Company Profiles ......122
  • 8. 8 All rights reserved at BIS Research Inc. R a d i o l i g a n d T h e r a p y M a r k e t 11.1 Overview.........................................................................................................123 11.2 Johnson & Johnson Services, Inc. ..............................................................124 11.2.1 Company Overview.............................................................................124 11.2.2 Role of Johnson & Johnson Services, Inc. in the Global Radioligand Therapy Market ...........................................................124 11.2.3 Product ASP (by Region) ...................................................................125 11.2.4 Key Competitors of Company............................................................125 11.2.5 Financials ............................................................................................126 11.2.6 Key Insights About the Financial Health of the Company...............128 11.2.7 SWOT Analysis....................................................................................129 11.3 Pfizer Inc.........................................................................................................130 11.3.1 Company Overview.............................................................................130 11.3.2 Role of Pfizer Inc. in the Global Radioligand Therapy Market.........130 11.3.3 Product ASP (by Region) ...................................................................130 11.3.4 Key Competitors of Company............................................................131 11.3.5 Financials ............................................................................................132 11.3.6 Key Insights About Financial Health of the Company.....................133 11.3.7 Business Strategies............................................................................133 11.3.7.1 Product Approval ............................................................................................. 133 11.3.8 SWOT Analysis....................................................................................134 11.4 Amneal Pharmaceuticals LLC. .....................................................................135 11.4.1 Company Overview.............................................................................135 11.4.2 Role of Amneal Pharmaceuticals LLC. in the Global Radioligand Therapy Market.................................................................................135 11.4.3 Key Competitors of Company............................................................135 11.4.4 Financials ............................................................................................136 11.4.5 Key Insights About Financial Health of the Company .....................137 11.4.6 Business Strategies............................................................................138 11.4.6.1 Product Launch................................................................................................ 138 11.4.7 SWOT Analysis....................................................................................138 11.5 Novartis International AG..............................................................................139
  • 9. 9 All rights reserved at BIS Research Inc. R a d i o l i g a n d T h e r a p y M a r k e t 11.5.1 Company Overview.............................................................................139 11.5.2 Role of Novartis International AG in the Global Radioligand Therapy Market.................................................................................139 11.5.3 Product ASP (by Region) ...................................................................139 11.5.4 Key Competitors of Company............................................................140 11.5.5 Financials ............................................................................................141 11.5.6 Key Insights About Financial Health of the Company .....................142 11.5.7 Corporate Strategies...........................................................................143 11.5.7.1 Mergers and Acquisitions ................................................................................ 143 11.5.7.2 Synergistic Activities........................................................................................ 143 11.5.7.3 Business Expansion and Funding ................................................................... 143 11.5.8 Business Strategies............................................................................143 11.5.8.1 Product Launches and Approval...................................................................... 144 11.5.9 SWOT Analysis....................................................................................145 11.6 POINT Biopharma Global Inc........................................................................146 11.6.1 Company Overview.............................................................................146 11.6.2 Role of POINT Biopharma Global Inc in the Global Radioligand Therapy Market.................................................................................146 11.6.3 Key Competitors of Company............................................................146 11.6.4 Corporate Strategies...........................................................................147 11.6.5 SWOT Analysis....................................................................................148 11.7 Fusion Pharma...............................................................................................149 11.7.1 Company Overview.............................................................................149 11.7.2 Role of Fusion Pharma in the Global Radioligand Therapy Market ...............................................................................................149 11.7.3 Key Competitors of Company............................................................149 11.7.4 Financials ............................................................................................150 11.7.5 Key Insights About the Financial Health of the Company...............151 11.7.6 Corporate Strategies...........................................................................151 11.7.6.1 Synergistic Activities........................................................................................ 151 11.7.7 SWOT Analysis....................................................................................152
  • 10. 10 All rights reserved at BIS Research Inc. R a d i o l i g a n d T h e r a p y M a r k e t 11.8 Clovis Oncology ............................................................................................153 11.8.1 Company Overview.............................................................................153 11.8.2 Role of Clovis Oncology in the Global Radioligand Therapy Market ...............................................................................................153 11.8.3 Key Competitors of Company............................................................153 11.8.4 Financials ............................................................................................154 11.8.5 Key Insights About the Financial Health of the Company...............155 11.8.6 Corporate Strategies...........................................................................156 11.8.6.1 Mergers and Acquisitions ................................................................................ 156 11.8.7 SWOT Analysis....................................................................................156 11.9 Telix Pharmaceuticals ...................................................................................157 11.9.1 Company Overview.............................................................................157 11.9.2 Role of Telix Pharmaceuticals in the Global Radioligand Therapy Market.................................................................................157 11.9.3 Key Competitors of Company............................................................157 11.9.4 Financials ............................................................................................158 11.9.5 Key Insights About the Financial Health of the Company...............159 11.9.6 Corporate Strategies...........................................................................159 11.9.6.1 Mergers and Acquisitions ................................................................................ 159 11.9.6.2 Synergistic Activities........................................................................................ 159 11.9.7 SWOT Analysis....................................................................................160 11.10 Lantheus Holdings, Inc. (Progenics Pharmaceuticals) ..............................161 11.10.1 Company Overview.............................................................................161 11.10.2 Role of Lantheus Holdings Inc., (Progenics Pharmaceuticals) in the Global Radioligand Therapy Market.........................................161 11.10.3 Key Competitors of Company............................................................161 11.10.4 Financials ............................................................................................162 11.10.5 Key Insights About the Financial Health of the Company...............164 11.10.6 Corporate Strategies...........................................................................164 11.10.6.1 Mergers and Acquisitions ................................................................................ 164 11.10.7 SWOT Analysis....................................................................................165
  • 11. 11 All rights reserved at BIS Research Inc. R a d i o l i g a n d T h e r a p y M a r k e t 11.11 Bayer AG ........................................................................................................166 11.11.1 Company Overview.............................................................................166 11.11.2 Role of Bayer AG in the Global Radioligand Therapy Market .........166 11.11.3 Product ASP (by Region) ...................................................................166 11.11.4 Key Competitors of Company............................................................166 11.11.5 Financials ............................................................................................167 11.11.6 Key Insights About the Financial Health of the Company...............168 11.11.7 Corporate Strategies...........................................................................169 11.11.7.1 Mergers and Acquisitions ................................................................................ 169 11.11.7.2 Product Approval ............................................................................................. 169 11.11.8 SWOT Analysis....................................................................................169 11.12 Molecular Partners ........................................................................................170 11.12.1 Company Overview.............................................................................170 11.12.2 Role of Molecular Partners in the Global Radioligand Therapy Market ...............................................................................................170 11.12.3 Key Competitors of Company............................................................170 11.12.4 SWOT Analysis....................................................................................171 12. Emerging Company Profiles.....................................................172 12.1 ITM Isotope Technologies Munich SE .........................................................172 12.1.1 Company Overview.............................................................................172 12.1.2 Role of ITM Isotope Technologies Munich SE in the Global Radioligand Therapy Market ...........................................................172 12.1.3 Key Competitors of Company............................................................172 12.1.4 SWOT Analysis....................................................................................173 12.2 Curium Pharma..............................................................................................174 12.2.1 Company Overview.............................................................................174 12.2.2 Role of Curium Pharma. in the Global Radioligand Therapy Market ...............................................................................................174 12.2.3 Key Competitors of Company............................................................174 12.2.4 SWOT Analysis....................................................................................175
  • 12. 12 All rights reserved at BIS Research Inc. R a d i o l i g a n d T h e r a p y M a r k e t 12.3 Precirix ...........................................................................................................176 12.3.1 Company Overview.............................................................................176 12.3.2 Role of Precirix in the Global Radioligand Therapy Market ............176 12.3.3 Key Competitors of Company............................................................176 12.3.4 SWOT Analysis....................................................................................177 12.4 Radio Medix....................................................................................................178 12.4.1 Company Overview.............................................................................178 12.4.2 Role of Radio Medix in the Global Radioligand Therapy Market ....178 12.4.3 Key Competitors of Company............................................................178 12.4.4 SWOT Analysis....................................................................................179
  • 13. 13 All rights reserved at BIS Research Inc. R a d i o l i g a n d T h e r a p y M a r k e t List of Figures Figure 1: Global Cancer Burden, 2020 Figure 2: Impact Analysis of Market Drivers and Market Challenges on the Global Radioligand Therapy Market Figure 3: Revenue Contribution of Different Segments, 2020, 2029, and 2031 Figure 4: Revenue Contribution of Different Segments, 2020, 2021, and 2031 Figure 5: Revenue Contribution of Different Segments, 2020, 2021, and 2031 Figure 6: Global Radioligand Therapy Market (by Region), $Million, 2023-2031 Figure 7: Global Radioligand Therapy Methodology Figure 8: Primary Research Methodology Figure 9: Epidemiology-Based Approach Figure 10: Global Radioligand Therapy Market Segmentation Figure 11: Global Radioligand Therapy Market, $Million, 2020-2031 Figure 12: Clinical Trial Authorization for Radioligand Therapy in the U.S. Figure 13: Steps for Obtaining Marketing Authorization Figure 14: U.S. FDA Review Timeline Figure 15: EMA Review Timeline Figure 16: Radioligand Therapy Global Clinical Trials (by Phase), 2021 Figure 17: Radioligand Therapy Global Clinical Trials 2021 Figure 18: 177Lu-PSMA-617 (RA101495) Mechanism of Action Figure 19: [Lu-177]-PNT2002 Phase III Clinical Trial Design for Metastatic Castration-Resistant Prostate Cancer Figure 20: 177Lu-PNT2002 Phase II Clinical Trial Design for Metastatic Castration-Resistant Prostate Cancer Figure 21: 177Lu-PNT2002 PK/PD Profile Results Figure 22: CAM H2 Phase I Portion Clinical Study Figure 23: Solid Tumors with Overexpression Figure 24: (177Lu)-NeoB Preclinical Studies Framework Figure 25: (177Lu)-NeoB Phase I Portion Clinical Study Figure 26: Phase III clinical Design for PNT-2003 Figure 27: Results from ITM-11 Phase III Clinical Trial Figure 28: 177Lu-FAP-2286 I/IIa Portion Clinical Study Figure 29: FPI-1434 I/IIa Portion Clinical Study Figure 30: Phase III clinical Design for PNT-2003 Figure 31: Global Cancer Burden, 2020 Figure 32: Share of Key Developments, January 2018-February 2022 Figure 33: Share of Product Approvals (by Company), January 2018-November 2021 Figure 34: Share of Synergistic Activities (by Company), January 2018-February 2022 Figure 35: Share of Mergers and Acquisitions (by Company), January 2018-February 2022
  • 14. 14 All rights reserved at BIS Research Inc. R a d i o l i g a n d T h e r a p y M a r k e t Figure 36: Market Share Analysis of Global Radio Ligand Therapy Market (by Company), 2020 Figure 37: Revenue Contribution of Different Segments, 2020, 2039, and 2031 Figure 38: Global Radioligand Therapy Market (Prostate Cancer), $Million, 2020-2031 Figure 39: Global Radioligand Therapy Market (Neuroendocrine Tumors), $Million, 2025-2031 Figure 40: Global Radioligand Therapy Market (Others), $Million, 2029-2031 Figure 41: Global Radioligand Therapy Market Segmentation (by Product) Figure 42: Global Radioligand Therapy Market (Approved Products), $Million, 2020-2031 Figure 43: Global Radioligand Therapy Market (Lutathera), $Million, 2020-2031 Figure 44: Global Radioligand Therapy Market (Zytiga), $Million, 2020-2031 Figure 45: Global Radioligand Therapy Market (Xtandi), $Million, 2020-2031 Figure 46: Global Radioligand Therapy Market (Xofigo), $Million, 2020-2031 Figure 47: Global Radioligand Therapy Market (Potential Pipeline), $Million, 2024-2031 Figure 48: Global Radioligand Therapy Market (by Potential Pipeline Drugs (Phase 3)), $Million, 2024- 2031 Figure 49: Global Radioligand Therapy Market (by Potential Pipeline Drugs (Phase 2)), $Million, 2029- 2031 Figure 50: Global Radioligand Therapy Market (by Biomarker) Figure 51: Global Radioligand Therapy Market (by Biomarker), $Million, 2020 and 2031 Figure 52: Global Radioligand Therapy Market (Prostate-Specific Membrane Antigen), $Million, 2020- 2031 Figure 53: Global Radioligand Therapy Market (Ki 67 Expression and Grading), $Million, 2020-2031 Figure 54: Global Radioligand Therapy Market (Cytochrome P450 17A1 Inhibitor), $Million, 2020-2031 Figure 55: Global Radioligand Therapy Market Snapshot (by Region), $Million, 2020-2031 Figure 56: Global Radioligand Therapy Market (by Region), $Million, 2020-2031 Figure 57: North America Radioligand Therapy Market, $Million, 2020-2031 Figure 58: North America: Market Dynamics Figure 59: North America Radioligand Therapy Market (by Country), $Million, 2020-2031 Figure 60: U.S. Radioligand Therapy Market, $Million, 2020-2031 Figure 61: Canada Radioligand Therapy Market, $Million, 2020-2031 Figure 62: Europe Radioligand Therapy Market, $Million, 2020-2031 Figure 63: Europe: Market Dynamics Figure 64: Europe Radioligand Therapy Market (by Country), $Million, 2020-2031 Figure 65: Germany Radioligand Therapy Market, $Million, 2020-2031 Figure 66: France Radioligand Therapy Market, $Million, 2020-2031 Figure 67: U.K. Radioligand Therapy Market, $Million, 2020-2031 Figure 68: Italy Radioligand Therapy Market, $Million, 2020-2031 Figure 69: Spain Radioligand Therapy Market, $Million, 2020-2031 Figure 70: Rest-of Europe Radioligand Therapy Market, $Million, 2020-2031 Figure 71: Asia-Pacific Radioligand Therapy Market, $Million, 2020-2031 Figure 72: Asia-Pacific: Market Dynamics Figure 73: APAC Radioligand Therapy Market (by Country), $Million, 2020-2031
  • 15. 15 All rights reserved at BIS Research Inc. R a d i o l i g a n d T h e r a p y M a r k e t Figure 74: Japan Radioligand Therapy Market, $Million, 2020-2031 Figure 75: South Korea Radioligand Therapy Market, $Million, 2020-2031 Figure 76: Australia Radioligand Therapy Market, $Million, 2020-2031 Figure 77: RoAPAC Radioligand Therapy Market, $Million, 2020-2031 Figure 78: Rest-of-the-World (RoW) Radioligand Therapy Market, $Million, 2020-2031 Figure 79: Total Number of Companies Profiled Figure 80: Johnson & Johnson Services, Inc.: Product Portfolio Figure 81: Johnson & Johnson Services, Inc.: Overall Financials, $Million, 2018-2020 Figure 82: Johnson & Johnson Services, Inc.: Revenue (by Segment), $Million, 2018-2020 Figure 83: Johnson & Johnson Services, Inc.: Revenue (by Region), $Million, 2018-2020 Figure 84: Johnson & Johnson Services, Inc.: R&D Expenditure, $Million, 2018-2020 Figure 85: Johnson & Johnson Services, Inc.: SWOT Analysis Figure 86: Pfizer Inc.: Commercialized Therapy Figure 87: Pfizer Inc.: Overall Financials, $Million, 2018-2020 Figure 88: Pfizer Inc.: Revenue (by Region), $Million, 2018-2020 Figure 89: Pfizer Inc.: R&D Expenditure, $Million, 2018-2020 Figure 90: Pfizer Inc.: SWOT Analysis Figure 91: Amneal Pharmaceuticals LLC.: Commercialized Therapy Figure 92: Amneal Pharmaceuticals LLC.: Overall Financials, $Million, 2018-2020 Figure 93: Amneal Pharmaceuticals LLC.: Revenue (by Segment), $Million, 2018-2020 Figure 94: Amneal Pharmaceuticals LLC.: R&D Expenditure, $Million, 2018-2020 Figure 95: Amneal Pharmaceuticals.: SWOT Analysis Figure 96: Novartis International AG: Commercialized Therapy Figure 97: Novartis International AG: Pre-Clinical and Clinical Assets Figure 98: Novartis International AG: Overall Financials, $Million, 2018-2020 Figure 99: Novartis International AG: Revenue (by Segment), $Million, 2018-2020 Figure 100: Novartis International AG: Revenue (by Region), $Million, 2018-2020 Figure 101: Novartis International AG: R&D Expenditure, $Million, 2018-2020 Figure 102: Novartis International AG: SWOT Analysis Figure 103: POINT Biopharma Global Inc.: Pipeline Therapy Figure 104: POINT Biopharma Global Inc.: SWOT Analysis Figure 105: Fusion Pharma: Pipeline Portfolio Figure 106: Fusion Pharma: Overall Financials, $Million, 2019-2020 Figure 107: Fusion Pharma: R&D Expenditure, $Million, 2019-2020 Figure 108: Fusion Pharma: SWOT Analysis Figure 109: Clovis Oncology.: Pipeline Portfolio Figure 110: Clovis Oncology.: Overall Financials, $Million, 2018-2020 Figure 111: Clovis Oncology.: Revenue (by Region), $Million, 2019-2020 Figure 112: Clovis Oncology.: R&D Expenditure, $Million, 2018-2020 Figure 113: Clovis Oncology.: SWOT Analysis
  • 16. 16 All rights reserved at BIS Research Inc. R a d i o l i g a n d T h e r a p y M a r k e t Figure 114: Telix Pharmaceuticals: Product Portfolio Figure 115: Telix Pharmaceuticals: Overall Financials, $Million, 2018-2020 Figure 116: Telix Pharmaceuticals: R&D Expenditure, $Million, 2018-2020 Figure 117: Telix Pharmaceuticals.: SWOT Analysis Figure 118: Lantheus Holdings Inc., (Progenics Pharmaceuticals): Pipeline Portfolio Figure 119: Lantheus Holdings Inc. (Progenics Pharmaceuticals): Overall Financials, $Million, 2018- 2020 Figure 120: Lantheus Holdings Inc. (Progenics Pharmaceuticals): Revenue (by Segment), $Million, 2019 and 2020 Figure 121: Lantheus Holdings Inc. (Progenics Pharmaceuticals): Revenue (by Region), $Million, 2018-2020 Figure 122: Lantheus Holdings Inc. (Progenics Pharmaceuticals): R&D Expenditure, $Million, 2018- 2020 Figure 123: Lantheus Holdings Inc. (Progenics Pharmaceuticals): SWOT Analysis Figure 124: Bayer AG.: Product Portfolio Figure 125: Bayer AG.: Overall Financials, $Million, 2018-2020 Figure 126: Bayer AG: Revenue (by Region), $Million, 2018-2020 Figure 127: Bayer AG.: R&D Expenditure, $Million, 2018-2020 Figure 128: Bayer AG.: SWOT Analysis Figure 129: Molecular Partners.: Product Portfolio Figure 130: Molecular Partners.: SWOT Analysis Figure 131: ITM Isotope Technologies Munich SE: Product Portfolio Figure 132: ITM Isotope Technologies Munich SE: SWOT Analysis Figure 133: Curium Pharma.: Product Portfolio Figure 134: Curium Pharma: SWOT Analysis Figure 135: Precirix: Product Portfolio Figure 136: Precirix: SWOT Analysis Figure 137: Radiomedix: Product Portfolio Figure 138: RadioMedix: SWOT Analysis
  • 17. 17 All rights reserved at BIS Research Inc. R a d i o l i g a n d T h e r a p y M a r k e t List of Tables Table 1: Regulatory Scenario of Radioligand Therapy Table 2: Emerging Radioligand Therapy Pipeline Table 3: Likert Scale Table 4: Impact Analysis of Market Drivers Table 5: Impact Analysis of Market Restraints Table 6: Lutathera ASP by Region Table 7: Xtandi: Indications
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