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[object Object],[object Object],[object Object],[object Object],[object Object],Introduction to case Outline
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Slide  Conclusion
Introduction to Case ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Slide
Slide
Slide  2005 Most Admired  Biotech Company
Background Slide  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
1AVASTIN : drug for patients with previously untreated metastatic cancer of the colon or rectum Slide  Overview Mission   To be the leading biotechnology company, using human genetic information to discover, develop, manufacture and commercialize biotherapeutics that address significant unmet medical needs.  In 2003  Revenues  : $3,300 million 79 %  from product sales Net Income: $563 million In 2004 AVASTIN 1  was approved by FDA First nine months of 2004 sales of AVASTIN 15 %  or $2,684,000 million TARCEVA & OMNITARG both drugs that Genentech promise to launch in the next year
Genentech  Product  Information (2001-2003) Slide  ($ in  millions)
Organization ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Slide  In 2004 Product Operation    Product development   Part in
Ebersman ,[object Object],[object Object],[object Object],Slide
Manufacturing  Process ,[object Object],Slide  To  created drugs based on recombinant DNA (inserting DNA  into cells  to  produce protein) Operation  Locations Vacaville (CA ) Porri ño  Spain
Production  Process Slide
Manufacturing  Process Flow Chart (per Batch) Slide  2,000L 12,000L ( 0.75gm/L )
Slide  Ultra  Filtration Frozen  Bulk Packaged  Products
Opportunities & Challenges ,[object Object],Slide  ,[object Object],[object Object],[object Object]
Slide
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Capacity  Overview Slide  In  2000  FDA  approved  for  CCP1 In  2004  CCP1  became a  Genentech’s  high  volume  drugs (Rituxan , Herceptin , Xolair and Avastin  Capacity : 12  12,000liter  production vessels
Vacaville  Expansion  ,[object Object],Slide  >>In  developing  CCP2  , - double  capacity  in  each  line  (build  eight 25,000 liter production vessels) - without  higher  expenditure Capacity : 8  25,000liter  production vessels
Contract  Manufacturing  Relationships ,[object Object],Slide
[object Object],Slide  ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],Potential  Market  Size Slide
A model for all cancer indication Slide
Slide  Capacity Planning Demand-upside Demand-Basecase Demand- Downside Sample  Capacity Requirements Chart
Slide  Plan Economic optimum  a Total Product Demand (kilograms) Distribution of Possible Demand Scenerios
Capacity Expansion Options ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Slide
[object Object],[object Object],[object Object],[object Object],Location Slide
Plant Size and Design Slide
Conclusion Slide
Slide

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Genentech's capacity expansion options to meet growing demand for cancer drug Avastin

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  • 6. Slide 2005 Most Admired Biotech Company
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  • 8. 1AVASTIN : drug for patients with previously untreated metastatic cancer of the colon or rectum Slide Overview Mission To be the leading biotechnology company, using human genetic information to discover, develop, manufacture and commercialize biotherapeutics that address significant unmet medical needs. In 2003 Revenues : $3,300 million 79 % from product sales Net Income: $563 million In 2004 AVASTIN 1 was approved by FDA First nine months of 2004 sales of AVASTIN 15 % or $2,684,000 million TARCEVA & OMNITARG both drugs that Genentech promise to launch in the next year
  • 9. Genentech Product Information (2001-2003) Slide ($ in millions)
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  • 14. Manufacturing Process Flow Chart (per Batch) Slide 2,000L 12,000L ( 0.75gm/L )
  • 15. Slide Ultra Filtration Frozen Bulk Packaged Products
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  • 23. A model for all cancer indication Slide
  • 24. Slide Capacity Planning Demand-upside Demand-Basecase Demand- Downside Sample Capacity Requirements Chart
  • 25. Slide Plan Economic optimum a Total Product Demand (kilograms) Distribution of Possible Demand Scenerios
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  • 28. Plant Size and Design Slide
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