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Diabetes mellitus:
Strategies for control
Aznida Firzah Abdul Aziz
MBBS MMed (Fam Med)
Department of Family Medicine
Faculty of Medicine
Universiti Kebangsaan Malaysia
Introduction
• Diabetes mellitus is a major global public health problem.
• Estimated world prevalence of diabetes among adults
(aged 20–79 years) in 2010: 6.4%, affecting 285 million
adults.
• In 2030: increase to 7.7%, and 439 million adults.
• 69% increase in numbers of adults with diabetes in
developing countries
• 20% increase in developed countries.
Diabetes Research and Clinical Practice 2010 87, 4-14
Fig. 1
Diabetes Research and Clinical Practice 2010 87, 4-14DOI: (10.1016/j.diabres.2009.10.007)
Diabetes Research and Clinical Practice 2010 87, 4-14DOI: (10.1016/j.diabres.2009.10.007)
Global estimates of the prevalence of diabetes 2010 & 2030
Epidemiology- Malaysian scenario
• Prevalence of diabetes 15.2%, 2.6 million Malaysians,
≥ 18yrs1
• 7.2% known diabetics, 8% previously undiagnosed
• Inpatient: 188 admissions per 100 0001
• Outpatient: 3,123,981 attendances at MOH Health clinics /
Klinik Kesihatan, 10% of total outpatient attendances2
1NHMS IV (2011)
2MOH Annual Report 2011
Prevalence of Diabetes
8.3
14.9
20.8
6.5
9.5
10.7
1.8
5.4
10.1
4.3
4.7
5.3
0
5
10
15
20
25
NHMS II (1996) NHMS III (2006) NHMS 2011
Prevalence(%) Prevalence of Diabetes, ≥30 years
(1996, 2006 & 2011)
Total diabetes
Known
Undiagnosed
IFG
Economic burden
• Ambulatory or outpatient care for diabetes patients cost
the Ministry of Health RM 836 million, which took up 2.2%
of the nation’s total health expenditure for 2009
• Average provider cost per outpatient visit for diabetes
treatment at primary care was RM393.24, compared to
RM 2707.44 at Specialist diabetic clinics.
3Wan Norlida I. 2014. The economic burden of type 2 diabetes mellitus
outpatient care and comparing cost-effectiveness of diabetes care in
primary health clinics and tertiary diabetic clinics. (Phd Thesis)
NationalStrategic Planningfor
Non-Communicablediseases(NSPNCD)4
(2010-2014)
• Primary prevention
• Early risk factor prevention
• Clinical preventive services
• Aim to reduce long-term complications and morbidity
related to diabetes
Risk factors
• Life-style related:
sedentary lifestyles5,
dietary indiscretions
• Age –related: late onset
diabetes, pancreas
insufficiency
• Hereditary: risk in
offspring of one diabetic
parent: 30%, both
parents: 60%
• Gen Y?
5Biswas, A. Ann Intern Med. 2015;162:123-132, 146-147
Risk factor: Obesity
• Adults (≥18yrs)
• 33.3% (5.4 million) pre obese
• 27.2% (4.4 million) obese
• Children (<18yrs, based on weight for age)
• 3.9% (0.3 million) obese
Who should be screened?
Individuals with symptoms suggestive of DM (tiredness,
lethargy, polyuria, polydipsia, polyphagia, weight loss, pruritis
vulvae, balanitis)
Criteria for testing for pre-diabetes and diabetes in
asymptomatic adult individuals:
All adults who are overweight [body mass index (BMI) >23
kg/m2 or
waist circumference (WC) ≥80 cm for women & ≥90 cm for men]
CPG on DM 2009. Malaysian Endocrine & Metabolic Society, Ministry of Health
Malaysia, Academy of Medicine Malaysia & Persatuan Diabetis Malaysia
American Diabetes Association (ADA).
and have additional risk factors:
• Dyslipidaemia either HDL
cholesterol <0.9 mmol/L or TG >1.7
mmol/L
• History of cardiovascular disease
(CVD)
• Hypertension (≥140/90 mmHg or
on therapy for hypertension)
• Impaired Glucose Tolerance (IGT)
or Impaired Fasting Glucose (IFG)
on previous testing
• First-degree relative with diabetes
• Other clinical conditions
associated with insulin resistance
(e.g. severe obesity and acanthosis
nigricans)
• Physical inactivity
• Women with polycystic ovarian
syndrome (PCOS)
Glycaemic control* of patients
with DM- what is the status?
*HbA1c reflects overall glucose control over a 3 month period
Diabetescontrolin Malaysia-DiabCare2008
M Mafauzy, Z Hussein, SP Chan. 2011. MJM 66(3):175-181
Glycaemic control
M Mafauzy, Z Hussein, SP Chan. 2011. MJM 66(3):175-181
National Diabetes Registry (2009-2012)
• From 644 primary healthcare
clinics (Klinik Kesihatan or KK)
• 657,839 patients registered
• Mean age 59.7 yrs
• 58.4% females
• Mean age at diagnosis: 53 yrs
• Mean duration of f/up 6.5 yrs
• Malays 58.9%, Chinese 21.4%,
Indians 15.3%
• Mean HbA1c 8.1%
• 23.8% achieved HbA1c < 6.5%
• 70.1% hypertensive
• 55.1% dyslipidaemia
Glycaemic control
Table 6 below shows the mean HbA1c and the percentage of patients reaching clinical targets for
HbA1c. Mean HbA1c has decreased slightly over 4 years, from 8.3% in 2009 to 8.1% in 2012 with most
audited patients recording HbA1c between 8.0% to 10.0%. In 2012, 23.8% of patients achieved the
Malaysian glycaemic target of HbA1c <6.5% compared to 19.4% in 2009. Assessed against the
international treatment target of HbA1c <7.0%, 37.9% of patients in 2012 would be considered to have
achieved glycaemic control.
Table 6. Mean HbA1c and patients achieving glycaemic targets* [Audit Dataset]
HbA1c 2009 2010 2011 2012
Mean %, (95% CI) 8.3 (8.3 - 8.3) 8.0 (8.0 - 8.0) 8.2 (8.2 - 8.2) 8.1 (8.1 - 8.1)
Distribution, n (%)
<6.5%** 10,559 (19.4) 12,079 (24.8) 11550 (22.6) 22,992 (23. 8)
<7.0% 17,266 (31.3) 18,948 (38.9) 18002 (35.3) 36,620 (37.9)
<8.0% 28,822 (52.9) 28,584 (58.6) 28169 (55.2) 55,635(57.5)
≥10.0% 11,480 (21.1) 8,803 (18.1) 10327 (20.2) 18,764 (19.4)
No. of patients with
HbA1c test results*
54,440 48,774 51,026 96,694
Note:
*The denominator for the percentage achieving target was the number of patients with HbA1c test results
**Good glycaemic control as defined by the Malaysian CPG on T2DM (2009)
Table 7 below shows that the achievement of HbA1c treatment target (<6.5%) varied across the states.
The national HbA1c treatment achievement rate was 23.8% in 2012. The achievement rate by states
ranged from 54.0% in Labuan and 39.1% in Sarawak to 17.6% and 14.9% in Terengganu and Kelantan,
respectively. In line with the overall increasing proportion of patients achieving treatment target at
In summary
• Diabetes IS a major public health problem for Malaysia
• Economic burden is huge
• Efforts to control disease and reduce complications need to
improve
• Prevention is the best investment
• So, what is the plan?
10th Malaysia Plan
• Restructuring of healthcare financing and healthcare
delivery system, to ensure universal health coverage at
minimal cost
• Using existing infrastructure
• Ensuring continuity of care across:
• programmes
• healthcare settings
• healthcare providers
Primary Healthcare Clinic set up
Health
centreOutpatient
Department
Diagnostic Lab
Rehabilitation
Pharmacy
Maternal &
Child Health
Dental Health
Services
10th Malaysia Plan
• Restructuring of healthcare financing and healthcare
delivery system, to ensure universal health coverage at
minimal cost
• Using existing infrastructure
• Ensuring continuity of care across:
• programmes
• healthcare settings
• healthcare providers
Public Healthcentre set up
Health
centreOutpatient
Department
Rehabilitation
Diagnostic Lab
Pharmacy
Maternal &
Child Health
Dental Health
Services
Recommendationsto enhance
Clinical PreventiveServicesat
PublicPrimaryCare Healthcentres
• Identification of risk factors for diabetes
among patients attending Dental Care Services
• Overweight/obese, family history of DM, past
history of GDM, poor wound healing i.e. poor
response to periodontal treatment?
• ±Screen for DM at Dental Clinic OR
• Referral to Primary Care / Outpatient Clinic at
Healthcentres TRO DM
• Feedback from Primary Care to Dental Care,
vice versa
Recommendations
• Increase awareness
among healthcare
providers i.e. Primary
healthcare and Dental
Healthcare regarding
shared care approaches
• Include Dental health
check schedules into
current DM monitoring
schedule (“DM
Greenbook”)
Thank you
draznida@ppukm.ukm.edu.my

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Diabetes mellitus in Malaysia: Nation's strategies for control

  • 1. Diabetes mellitus: Strategies for control Aznida Firzah Abdul Aziz MBBS MMed (Fam Med) Department of Family Medicine Faculty of Medicine Universiti Kebangsaan Malaysia
  • 2. Introduction • Diabetes mellitus is a major global public health problem. • Estimated world prevalence of diabetes among adults (aged 20–79 years) in 2010: 6.4%, affecting 285 million adults. • In 2030: increase to 7.7%, and 439 million adults. • 69% increase in numbers of adults with diabetes in developing countries • 20% increase in developed countries. Diabetes Research and Clinical Practice 2010 87, 4-14
  • 3. Fig. 1 Diabetes Research and Clinical Practice 2010 87, 4-14DOI: (10.1016/j.diabres.2009.10.007) Diabetes Research and Clinical Practice 2010 87, 4-14DOI: (10.1016/j.diabres.2009.10.007) Global estimates of the prevalence of diabetes 2010 & 2030
  • 4. Epidemiology- Malaysian scenario • Prevalence of diabetes 15.2%, 2.6 million Malaysians, ≥ 18yrs1 • 7.2% known diabetics, 8% previously undiagnosed • Inpatient: 188 admissions per 100 0001 • Outpatient: 3,123,981 attendances at MOH Health clinics / Klinik Kesihatan, 10% of total outpatient attendances2 1NHMS IV (2011) 2MOH Annual Report 2011
  • 6. 8.3 14.9 20.8 6.5 9.5 10.7 1.8 5.4 10.1 4.3 4.7 5.3 0 5 10 15 20 25 NHMS II (1996) NHMS III (2006) NHMS 2011 Prevalence(%) Prevalence of Diabetes, ≥30 years (1996, 2006 & 2011) Total diabetes Known Undiagnosed IFG
  • 7. Economic burden • Ambulatory or outpatient care for diabetes patients cost the Ministry of Health RM 836 million, which took up 2.2% of the nation’s total health expenditure for 2009 • Average provider cost per outpatient visit for diabetes treatment at primary care was RM393.24, compared to RM 2707.44 at Specialist diabetic clinics. 3Wan Norlida I. 2014. The economic burden of type 2 diabetes mellitus outpatient care and comparing cost-effectiveness of diabetes care in primary health clinics and tertiary diabetic clinics. (Phd Thesis)
  • 8. NationalStrategic Planningfor Non-Communicablediseases(NSPNCD)4 (2010-2014) • Primary prevention • Early risk factor prevention • Clinical preventive services • Aim to reduce long-term complications and morbidity related to diabetes
  • 9. Risk factors • Life-style related: sedentary lifestyles5, dietary indiscretions • Age –related: late onset diabetes, pancreas insufficiency • Hereditary: risk in offspring of one diabetic parent: 30%, both parents: 60% • Gen Y? 5Biswas, A. Ann Intern Med. 2015;162:123-132, 146-147
  • 10. Risk factor: Obesity • Adults (≥18yrs) • 33.3% (5.4 million) pre obese • 27.2% (4.4 million) obese • Children (<18yrs, based on weight for age) • 3.9% (0.3 million) obese
  • 11. Who should be screened? Individuals with symptoms suggestive of DM (tiredness, lethargy, polyuria, polydipsia, polyphagia, weight loss, pruritis vulvae, balanitis) Criteria for testing for pre-diabetes and diabetes in asymptomatic adult individuals: All adults who are overweight [body mass index (BMI) >23 kg/m2 or waist circumference (WC) ≥80 cm for women & ≥90 cm for men] CPG on DM 2009. Malaysian Endocrine & Metabolic Society, Ministry of Health Malaysia, Academy of Medicine Malaysia & Persatuan Diabetis Malaysia American Diabetes Association (ADA).
  • 12. and have additional risk factors: • Dyslipidaemia either HDL cholesterol <0.9 mmol/L or TG >1.7 mmol/L • History of cardiovascular disease (CVD) • Hypertension (≥140/90 mmHg or on therapy for hypertension) • Impaired Glucose Tolerance (IGT) or Impaired Fasting Glucose (IFG) on previous testing • First-degree relative with diabetes • Other clinical conditions associated with insulin resistance (e.g. severe obesity and acanthosis nigricans) • Physical inactivity • Women with polycystic ovarian syndrome (PCOS)
  • 13. Glycaemic control* of patients with DM- what is the status? *HbA1c reflects overall glucose control over a 3 month period
  • 14. Diabetescontrolin Malaysia-DiabCare2008 M Mafauzy, Z Hussein, SP Chan. 2011. MJM 66(3):175-181
  • 15. Glycaemic control M Mafauzy, Z Hussein, SP Chan. 2011. MJM 66(3):175-181
  • 16. National Diabetes Registry (2009-2012) • From 644 primary healthcare clinics (Klinik Kesihatan or KK) • 657,839 patients registered • Mean age 59.7 yrs • 58.4% females • Mean age at diagnosis: 53 yrs • Mean duration of f/up 6.5 yrs • Malays 58.9%, Chinese 21.4%, Indians 15.3% • Mean HbA1c 8.1% • 23.8% achieved HbA1c < 6.5% • 70.1% hypertensive • 55.1% dyslipidaemia
  • 17. Glycaemic control Table 6 below shows the mean HbA1c and the percentage of patients reaching clinical targets for HbA1c. Mean HbA1c has decreased slightly over 4 years, from 8.3% in 2009 to 8.1% in 2012 with most audited patients recording HbA1c between 8.0% to 10.0%. In 2012, 23.8% of patients achieved the Malaysian glycaemic target of HbA1c <6.5% compared to 19.4% in 2009. Assessed against the international treatment target of HbA1c <7.0%, 37.9% of patients in 2012 would be considered to have achieved glycaemic control. Table 6. Mean HbA1c and patients achieving glycaemic targets* [Audit Dataset] HbA1c 2009 2010 2011 2012 Mean %, (95% CI) 8.3 (8.3 - 8.3) 8.0 (8.0 - 8.0) 8.2 (8.2 - 8.2) 8.1 (8.1 - 8.1) Distribution, n (%) <6.5%** 10,559 (19.4) 12,079 (24.8) 11550 (22.6) 22,992 (23. 8) <7.0% 17,266 (31.3) 18,948 (38.9) 18002 (35.3) 36,620 (37.9) <8.0% 28,822 (52.9) 28,584 (58.6) 28169 (55.2) 55,635(57.5) ≥10.0% 11,480 (21.1) 8,803 (18.1) 10327 (20.2) 18,764 (19.4) No. of patients with HbA1c test results* 54,440 48,774 51,026 96,694 Note: *The denominator for the percentage achieving target was the number of patients with HbA1c test results **Good glycaemic control as defined by the Malaysian CPG on T2DM (2009) Table 7 below shows that the achievement of HbA1c treatment target (<6.5%) varied across the states. The national HbA1c treatment achievement rate was 23.8% in 2012. The achievement rate by states ranged from 54.0% in Labuan and 39.1% in Sarawak to 17.6% and 14.9% in Terengganu and Kelantan, respectively. In line with the overall increasing proportion of patients achieving treatment target at
  • 18. In summary • Diabetes IS a major public health problem for Malaysia • Economic burden is huge • Efforts to control disease and reduce complications need to improve • Prevention is the best investment • So, what is the plan?
  • 19. 10th Malaysia Plan • Restructuring of healthcare financing and healthcare delivery system, to ensure universal health coverage at minimal cost • Using existing infrastructure • Ensuring continuity of care across: • programmes • healthcare settings • healthcare providers
  • 20. Primary Healthcare Clinic set up Health centreOutpatient Department Diagnostic Lab Rehabilitation Pharmacy Maternal & Child Health Dental Health Services
  • 21. 10th Malaysia Plan • Restructuring of healthcare financing and healthcare delivery system, to ensure universal health coverage at minimal cost • Using existing infrastructure • Ensuring continuity of care across: • programmes • healthcare settings • healthcare providers
  • 22. Public Healthcentre set up Health centreOutpatient Department Rehabilitation Diagnostic Lab Pharmacy Maternal & Child Health Dental Health Services
  • 23. Recommendationsto enhance Clinical PreventiveServicesat PublicPrimaryCare Healthcentres • Identification of risk factors for diabetes among patients attending Dental Care Services • Overweight/obese, family history of DM, past history of GDM, poor wound healing i.e. poor response to periodontal treatment? • ±Screen for DM at Dental Clinic OR • Referral to Primary Care / Outpatient Clinic at Healthcentres TRO DM • Feedback from Primary Care to Dental Care, vice versa
  • 24. Recommendations • Increase awareness among healthcare providers i.e. Primary healthcare and Dental Healthcare regarding shared care approaches • Include Dental health check schedules into current DM monitoring schedule (“DM Greenbook”)