Highlights Huidelines 2010 CPR and ECC - AHA English
1. H i g h l i g h t s o f t h e 2010
American Heart Association
Guidelines for CPR and ECC
Contents
Major Issues Affecting
All Rescuers 1
Lay Rescuer Adult CPR 3
Healthcare Provider BLS 5
Electrical Therapies 9
CPR Techniques and Devices 12
Advanced Cardiovascular
Life Support 13
Acute Coronary Syndromes 17
Stroke 18
Pediatric Basic Life Support 18
Pediatric Advanced Life
Support 20
Neonatal Resuscitation 22
Ethical Issues 24
Education, Implementation,
and Teams 25
First Aid 26
Summary 28
3. MAJOR ISSUES
MAJOR ISSUES AFFECTING
T
his “Guidelines Highlights” publication summarizes ALL RESCUERS
the key issues and changes in the 2010
American Heart Association (AHA) Guidelines for
Cardiopulmonary Resuscitation (CPR) and Emergency This section summarizes major issues in the 2010 AHA
Cardiovascular Care (ECC). It has been developed for Guidelines for CPR and ECC, primarily those in basic life
resuscitation providers and for AHA instructors to focus on support (BLS) that affect all rescuers, whether healthcare
resuscitation science and guidelines recommendations that providers or lay rescuers. The 2005 AHA Guidelines for CPR
are most important or controversial or will result in changes in and ECC emphasized the importance of high-quality chest
resuscitation practice or resuscitation training. In addition, it compressions (compressing at an adequate rate and depth,
provides the rationale for the recommendations. allowing complete chest recoil after each compression, and
minimizing interruptions in chest compressions). Studies
Because this publication is designed as a summary, it does published before and since 2005 have demonstrated that (1) the
not reference the supporting published studies and does quality of chest compressions continues to require improvement,
not list Classes of Recommendations or Levels of Evidence. although implementation of the 2005 AHA Guidelines for CPR
For more detailed information and references, the reader is and ECC has been associated with better CPR quality and
encouraged to read the 2010 AHA Guidelines for CPR and greater survival; (2) there is considerable variation in survival
ECC, including the Executive Summary,1 published online from out-of-hospital cardiac arrest across emergency medical
in Circulation in October 2010 and to consult the detailed services (EMS) systems; and (3) most victims of out-of-hospital
summary of resuscitation science in the 2010 International sudden cardiac arrest do not receive any bystander CPR. The
Consensus on CPR and ECC Science With Treatment changes recommended in the 2010 AHA Guidelines for CPR
Recommendations, published simultaneously in Circulation2 and ECC attempt to address these issues and also make
and Resuscitation.3 recommendations to improve outcome from cardiac arrest
This year marks the 50th anniversary of the first peer-reviewed through a new emphasis on post–cardiac arrest care.
medical publication documenting survival after closed
Continued Emphasis on High-Quality CPR
chest compression for cardiac arrest,4 and resuscitation
experts and providers remain dedicated to reducing death
The 2010 AHA Guidelines for CPR and ECC once again
and disability from cardiovascular diseases and stroke.
emphasize the need for high-quality CPR, including
Bystanders, first responders, and healthcare providers all
play key roles in providing CPR for victims of cardiac arrest. • A compression rate of at least 100/min (a change from
In addition, advanced providers can provide excellent “approximately” 100/min)
periarrest and postarrest care.
• A compression depth of at least 2 inches (5 cm) in adults
The 2010 AHA Guidelines for CPR and ECC are based on and a compression depth of at least one third of the anterior-
an international evidence evaluation process that involved posterior diameter of the chest in infants and children
hundreds of international resuscitation scientists and experts (approximately 1.5 inches [4 cm] in infants and 2 inches
who evaluated, discussed, and debated thousands of peer- [5 cm] in children). Note that the range of 1½ to 2 inches is
reviewed publications. Information about the 2010 evidence no longer used for adults, and the absolute depth specified
evaluation process is contained in Box 1. for children and infants is deeper than in previous versions of
the AHA Guidelines for CPR and ECC.
BOX 1
Evidence Evaluation Process
The 2010 AHA Guidelines for CPR and ECC are based on an extensive review of resuscitation literature and many debates and
discussions by international resuscitation experts and members of the AHA ECC Committee and Subcommittees. The ILCOR 2010
International Consensus on CPR and ECC Science With Treatment Recommendations, simultaneously published in Circulation2 and
Resuscitation,3 summarizes the international consensus interpreting tens of thousands of peer-reviewed resuscitation studies. This
2010 international evidence evaluation process involved 356 resuscitation experts from 29 countries who analyzed, discussed, and
debated the resuscitation research during in-person meetings, conference calls, and online sessions (“webinars”) over a 36-month
period, including the 2010 International Consensus Conference on CPR and ECC Science With Treatment Recommendations, held
in Dallas, Texas, in early 2010. Worksheet experts produced 411 scientific evidence reviews of 277 topics in resuscitation and ECC.
The process included structured evidence evaluation, analysis, and cataloging of the literature. It also included rigorous disclosure and
management of potential conflicts of interest. The 2010 AHA Guidelines for CPR and ECC1 contain the expert recommendations for
application of the International Consensus on CPR and ECC Science With Treatment Recommendations with consideration of their
effectiveness, ease of teaching and application, and local systems factors.
H i g h l i g h t s o f t h e 2 0 1 0 A H A G u i d e l i n e s f o r C PR and ECC 1
4
4. M A J O R S C U UR S D U LT C P R
L AY R E I S S E E A
• Allowing for complete chest recoil after each compression required to deliver the first cycle of 30 chest compressions, or
approximately 18 seconds; when 2 rescuers are present for
• Minimizing interruptions in chest compressions
resuscitation of the infant or child, the delay will be even shorter).
• Avoiding excessive ventilation
Most victims of out-of-hospital cardiac arrest do not receive
There has been no change in the recommendation for a any bystander CPR. There are probably many reasons for this,
compression-to-ventilation ratio of 30:2 for single rescuers of but one impediment may be the A-B-C sequence, which starts
adults, children, and infants (excluding newly born infants). The with the procedures that rescuers find most difficult, namely,
2010 AHA Guidelines for CPR and ECC continue to recommend opening the airway and delivering breaths. Starting with chest
that rescue breaths be given in approximately 1 second. Once compressions might encourage more rescuers to begin CPR.
an advanced airway is in place, chest compressions can be
Basic life support is usually described as a sequence of
continuous (at a rate of at least 100/min) and no longer cycled
actions, and this continues to be true for the lone rescuer.
with ventilations. Rescue breaths can then be provided at
Most healthcare providers, however, work in teams, and
about 1 breath every 6 to 8 seconds (about 8 to 10 breaths per
team members typically perform BLS actions simultaneously.
minute). Excessive ventilation should be avoided.
For example, one rescuer immediately initiates chest
A Change From A-B-C to C-A-B compressions while another rescuer gets an automated
external defibrillator (AED) and calls for help, and a third
rescuer opens the airway and provides ventilations.
The 2010 AHA Guidelines for CPR and ECC recommend a
change in the BLS sequence of steps from A-B-C (Airway, Healthcare providers are again encouraged to tailor rescue
Breathing, Chest compressions) to C-A-B (Chest compressions, actions to the most likely cause of arrest. For example,
Airway, Breathing) for adults, children, and infants (excluding the if a lone healthcare provider witnesses a victim suddenly
newly born; see Neonatal Resuscitation section). This fundamental collapse, the provider may assume that the victim has had a
change in CPR sequence will require reeducation of everyone primary cardiac arrest with a shockable rhythm and should
who has ever learned CPR, but the consensus of the authors and immediately activate the emergency response system,
experts involved in the creation of the 2010 AHA Guidelines for retrieve an AED, and return to the victim to provide CPR
CPR and ECC is that the benefit will justify the effort. and use the AED. But for a presumed victim of asphyxial
arrest such as drowning, the priority would be to provide
Why: The vast majority of cardiac arrests occur in adults,
chest compressions with rescue breathing for about 5 cycles
and the highest survival rates from cardiac arrest are reported
(approximately 2 minutes) before activating the emergency
among patients of all ages who have a witnessed arrest and
response system.
an initial rhythm of ventricular fibrillation (VF) or pulseless
ventricular tachycardia (VT). In these patients, the critical Two new parts in the 2010 AHA Guidelines for CPR and ECC
initial elements of BLS are chest compressions and early are Post–Cardiac Arrest Care and Education, Implementation,
defibrillation. In the A-B-C sequence, chest compressions and Teams. The importance of post–cardiac arrest care is
are often delayed while the responder opens the airway to emphasized by the addition of a new fifth link in the AHA
give mouth-to-mouth breaths, retrieves a barrier device, or ECC Adult Chain of Survival (Figure 1). See the sections
gathers and assembles ventilation equipment. By changing the Post–Cardiac Arrest Care and Education, Implementation,
sequence to C-A-B, chest compressions will be initiated sooner and Teams in this publication for a summary of key
and the delay in ventilation should be minimal (ie, only the time recommendations contained in these new parts.
Figure 1
AHA ECC Adult Chain of Survival
The links in the new AHA ECC Adult
Chain of Survival are as follows:
1. Immediate recognition of cardiac
arrest and activation of the
emergency response system
2. Early CPR with an emphasis on
chest compressions
3. Rapid defibrillation
4. Effective advanced life support
5. Integrated post–cardiac arrest care
2
3 American Heart Association
6. L A Y R E S C U E R A D U LT C P R
Change in CPR Sequence: C-A-B Rather Elimination of “Look, Listen, and Feel
Than A-B-C* for Breathing”*
2010 (New): Initiate chest compressions before ventilations. 2010 (New): “Look, listen, and feel” was removed from the
2005 (Old): The sequence of adult CPR began with opening of CPR sequence. After delivery of 30 compressions, the lone
the airway, checking for normal breathing, and then delivery of rescuer opens the victim’s airway and delivers 2 breaths.
2 rescue breaths followed by cycles of 30 chest compressions
2005 (Old): “Look, listen, and feel” was used to assess
and 2 breaths.
breathing after the airway was opened.
Why: Although no published human or animal evidence
demonstrates that starting CPR with 30 compressions Why: With the new “chest compressions first” sequence, CPR
rather than 2 ventilations leads to improved outcome, chest is performed if the adult is unresponsive and not breathing
compressions provide vital blood flow to the heart and or not breathing normally (as noted above, lay rescuers will
brain, and studies of out-of-hospital adult cardiac arrest be taught to provide CPR if the unresponsive victim is “not
showed that survival was higher when bystanders made breathing or only gasping”). The CPR sequence begins with
some attempt rather than no attempt to provide CPR. Animal compressions (C-A-B sequence). Therefore, breathing is briefly
data demonstrated that delays or interruptions in chest checked as part of a check for cardiac arrest; after the first set
compressions reduced survival, so such delays or interruptions of chest compressions, the airway is opened, and the rescuer
should be minimized throughout the entire resuscitation. Chest delivers 2 breaths.
compressions can be started almost immediately, whereas
positioning the head and achieving a seal for mouth-to-mouth Chest Compression Rate: At Least
or bag-mask rescue breathing all take time. The delay in 100 per Minute*
initiation of compressions can be reduced if 2 rescuers are
present: the first rescuer begins chest compressions, and the 2010 (New): It is reasonable for lay rescuers and healthcare
second rescuer opens the airway and is prepared to deliver providers to perform chest compressions at a rate of at least
breaths as soon as the first rescuer has completed the first 100/min.
set of 30 chest compressions. Whether 1 or more rescuers are
present, initiation of CPR with chest compressions ensures that 2005 (Old): Compress at a rate of about 100/min.
the victim receives this critical intervention early, and any delay
Why: The number of chest compressions delivered per
in rescue breaths should be brief.
minute during CPR is an important determinant of return
of spontaneous circulation (ROSC) and survival with good
BOX 2 neurologic function. The actual number of chest compressions
Number of Compressions Delivered delivered per minute is determined by the rate of chest
Affected by Compression Rate and compressions and the number and duration of interruptions in
by Interruptions compressions (eg, to open the airway, deliver rescue breaths,
or allow AED analysis). In most studies, more compressions are
The total number of compressions delivered during resuscitation associated with higher survival rates, and fewer compressions
is an important determinant of survival from cardiac arrest. are associated with lower survival rates. Provision of adequate
The number of compressions delivered is affected by the chest compressions requires an emphasis not only on an
compression rate and by the compression fraction (the portion adequate compression rate but also on minimizing interruptions
of total CPR time during which compressions are performed); to this critical component of CPR. An inadequate compression
increases in compression rate and fraction increase the total rate or frequent interruptions (or both) will reduce the total
compressions delivered, whereas decreases in compression number of compressions delivered per minute. For further
rate or compression fraction decrease the total compressions information, see Box 2.
delivered. Compression fraction is improved if you reduce
the number and length of any interruptions in compressions, Chest Compression Depth*
and it is reduced by frequent or long interruptions in chest
compressions. An analogy can be found in automobile travel.
2010 (New): The adult sternum should be depressed at least 2
When you travel in an automobile, the number of miles you
travel in a day is affected not only by the speed that you drive inches (5 cm).
(your rate of travel) but also by the number and duration of any
2005 (Old): The adult sternum should be depressed
stops you make (interruptions in travel). During CPR, you want
approximately 1½ to 2 inches (approximately 4 to 5 cm).
to deliver effective compressions at an appropriate rate (at least
100/min) and depth, while minimizing the number and duration Why: Compressions create blood flow primarily by increasing
of interruptions in chest compressions. Additional components intrathoracic pressure and directly compressing the heart.
of high-quality CPR include allowing complete chest recoil after
Compressions generate critical blood flow and oxygen and
each compression and avoiding excessive ventilation.
energy delivery to the heart and brain. Confusion may result
when a range of depth is recommended, so 1 compression
4 American Heart Association
7. H E A LT H C A R E P R O V I D E R B L S
depth is now recommended. Rescuers often do not compress • Compression depth for adults has been slightly altered to at
the chest enough despite recommendations to “push hard.” In least 2 inches (about 5 cm) from the previous recommended
addition, the available science suggests that compressions of range of about 1½ to 2 inches (4 to 5 cm).
at least 2 inches are more effective than compressions of
• Continued emphasis has been placed on the need to reduce
1½ inches. For this reason the 2010 AHA Guidelines for CPR
the time between the last compression and shock delivery
and ECC recommend a single minimum depth for compression
and the time between shock delivery and resumption of
of the adult chest.
compressions immediately after shock delivery.
• There is an increased focus on using a team approach
during CPR.
HEALTHCARE PROVIDER BLS
These changes are designed to simplify training for the
healthcare provider and to continue to emphasize the need to
Summary of Key Issues and Major Changes provide early and high-quality CPR for victims of cardiac arrest.
More information about these changes follows. Note: In the
Key issues and major changes in the 2010 AHA Guidelines following topics for healthcare providers, those that are similar
for CPR and ECC recommendations for healthcare providers for healthcare providers and lay rescuers are noted with
include the following: an asterisk (*).
• Because cardiac arrest victims may present with a short Dispatcher Identification of Agonal Gasps
period of seizure-like activity or agonal gasps that may
confuse potential rescuers, dispatchers should be specifically Cardiac arrest victims may present with seizure-like activity or
trained to identify these presentations of cardiac arrest to agonal gasps that may confuse potential rescuers. Dispatchers
improve cardiac arrest recognition. should be specifically trained to identify these presentations
• Dispatchers should instruct untrained lay rescuers to provide of cardiac arrest to improve recognition of cardiac arrest and
Hands-Only CPR for adults with sudden cardiac arrest. prompt provision of CPR.
• Refinements have been made to recommendations for 2010 (New): To help bystanders recognize cardiac arrest,
immediate recognition and activation of the emergency dispatchers should ask about an adult victim’s responsiveness,
response system once the healthcare provider identifies the if the victim is breathing, and if the breathing is normal, in an
adult victim who is unresponsive with no breathing or no attempt to distinguish victims with agonal gasps (ie, in those
normal breathing (ie, only gasping). The healthcare provider who need CPR) from victims who are breathing normally and
briefly checks for no breathing or no normal breathing (ie, do not need CPR. The lay rescuer should be taught to begin
no breathing or only gasping) when the provider checks CPR if the victim is “not breathing or only gasping.” The
responsiveness. The provider then activates the emergency healthcare provider should be taught to begin CPR if the victim
response system and retrieves the AED (or sends someone has “no breathing or no normal breathing (ie, only gasping).”
to do so). The healthcare provider should not spend more Therefore, breathing is briefly checked as part of a check for
than 10 seconds checking for a pulse, and if a pulse is not cardiac arrest before the healthcare provider activates the
definitely felt within 10 seconds, should begin CPR and use emergency response system and retrieves the AED (or sends
the AED when available. someone to do so), and then (quickly) checks for a pulse and
begins CPR and uses the AED.
• “Look, listen, and feel for breathing” has been removed from
the algorithm. 2005 (Old): Dispatcher CPR instructions should include
questions to help bystanders identify patients with occasional
• Increased emphasis has been placed on high-quality CPR gasps as likely victims of cardiac arrest to increase the
(compressions of adequate rate and depth, allowing complete likelihood of bystander CPR for such victims.
chest recoil between compressions, minimizing interruptions
in compressions, and avoiding excessive ventilation). Why: There is evidence of considerable regional variation in
the reported incidence and outcome of cardiac arrest in the
• Use of cricoid pressure during ventilations is generally United States. This variation is further evidence of the need for
not recommended. communities and systems to accurately identify each instance
• Rescuers should initiate chest compressions before giving of treated cardiac arrest and measure outcomes. It also
rescue breaths (C-A-B rather than A-B-C). Beginning CPR suggests additional opportunities for improving survival rates
with 30 compressions rather than 2 ventilations leads to a in many communities. Previous guidelines have recommended
shorter delay to first compression. the development of programs to aid in recognition of cardiac
arrest. The 2010 AHA Guidelines for CPR and ECC are more
• Compression rate is modified to at least 100/min from
approximately 100/min.
H i g h l i g h t s o f t h e 2 0 1 0 A H A G u i d e l i n e s f o r C PR and ECC 5
8. H E A LT H C A R E P R O V I D E R B L S
specific about the necessary components of resuscitation 2005 (Old): Cricoid pressure should be used only if the victim
systems. Studies published since 2005 have demonstrated is deeply unconscious, and it usually requires a third rescuer
improved outcome from out-of-hospital cardiac arrest, not involved in rescue breaths or compressions.
particularly from shockable rhythms, and have reaffirmed the
importance of a stronger emphasis on immediate provision Why: Cricoid pressure is a technique of applying pressure to
of high-quality CPR (compressions of adequate rate and the victim’s cricoid cartilage to push the trachea posteriorly
depth, allowing complete chest recoil after each compression, and compress the esophagus against the cervical vertebrae.
minimizing interruptions in chest compressions, and avoiding Cricoid pressure can prevent gastric inflation and reduce the
excessive ventilation). risk of regurgitation and aspiration during bag-mask ventilation,
but it may also impede ventilation. Seven randomized studies
To help bystanders immediately recognize cardiac arrest, showed that cricoid pressure can delay or prevent the
dispatchers should specifically inquire about an adult placement of an advanced airway and that some aspiration
victim’s absence of response, if the victim is breathing, and can still occur despite application of cricoid pressure. In
if any breathing observed is normal. Dispatchers should be addition, it is difficult to appropriately train rescuers in use of
specifically educated in helping bystanders detect agonal the maneuver. Therefore, the routine use of cricoid pressure in
gasps to improve cardiac arrest recognition. cardiac arrest is not recommended.
Dispatchers should also be aware that brief generalized Emphasis on Chest Compressions*
seizures may be the first manifestation of cardiac arrest. In
summary, in addition to activating professional emergency 2010 (New): Chest compressions are emphasized for
responders, the dispatcher should ask straightforward both trained and untrained rescuers. If a bystander is not
questions about whether the patient is responsive and trained in CPR, the bystander should provide Hands-Only
breathing normally to identify patients with possible cardiac (compression-only) CPR for the adult who suddenly collapses,
arrest. Dispatchers should provide Hands-Only (compression- with an emphasis to “push hard and fast” on the center of
only) CPR instructions to help untrained bystanders initiate the chest, or follow the directions of the emergency medical
CPR when cardiac arrest is suspected (see below). dispatcher. The rescuer should continue Hands-Only CPR
Dispatcher Should Provide CPR Instructions until an AED arrives and is ready for use or EMS providers
take over care of the victim.
2010 (New): The 2010 AHA Guidelines for CPR and ECC more Optimally all healthcare providers should be trained in BLS. In
strongly recommend that dispatchers should instruct untrained this trained population, it is reasonable for both EMS and in-
lay rescuers to provide Hands-Only CPR for adults who hospital professional rescuers to provide chest compressions
are unresponsive with no breathing or no normal breathing. and rescue breaths for cardiac arrest victims.
Dispatchers should provide instructions in conventional CPR
for victims of likely asphyxial arrest. 2005 (Old): The 2005 AHA Guidelines for CPR and ECC
did not provide different recommendations for trained and
2005 (Old): The 2005 AHA Guidelines for CPR and ECC untrained rescuers and did not emphasize differences in
noted that telephone instruction in chest compressions alone instructions provided to lay rescuers versus healthcare
may be preferable. providers, but did recommend that dispatchers provide
compression-only CPR instructions to untrained bystanders. In
Why: Unfortunately, most adults with out-of-hospital cardiac
addition, the 2005 AHA Guidelines for CPR and ECC noted that
arrest do not receive any bystander CPR. Hands-Only
if the rescuer was unwilling or unable to provide ventilations,
(compression-only) bystander CPR substantially improves
the rescuer should provide chest compressions. Note that the
survival after adult out-of-hospital cardiac arrests compared
AHA Hands-Only CPR statement was published in 2008.
with no bystander CPR. Other studies of adults with cardiac
arrest treated by lay rescuers showed similar survival rates Why: Hands-Only (compression-only) CPR is easier for
among victims receiving Hands-Only CPR versus those untrained rescuers to perform and can be more readily guided
receiving conventional CPR (ie, with rescue breaths). by dispatchers over the telephone. However, because the
Importantly, it is easier for dispatchers to instruct untrained healthcare provider should be trained, the recommendation
rescuers to perform Hands-Only CPR than conventional CPR remains for the healthcare provider to perform both
for adult victims, so the recommendation is now stronger compressions and ventilations. If the healthcare provider is
for them to do so, unless the victim is likely to have had an unable to perform ventilations, the provider should activate the
asphyxial arrest (eg, drowning). emergency response system and provide chest compressions.
Cricoid Pressure Activation of Emergency Response System
2010 (New): The routine use of cricoid pressure in cardiac 2010 (New): The healthcare provider should check for
arrest is not recommended. response while looking at the patient to determine if breathing
6 American Heart Association
9. H E A LT H C A R E P R O V I D E R B L S
is absent or not normal. The provider should suspect cardiac of cardiac arrest. After delivery of 30 compressions, the lone
arrest if the victim is not breathing or only gasping. rescuer opens the victim’s airway and delivers 2 breaths.
2005 (Old): The healthcare provider activated the emergency 2005 (Old): “Look, listen, and feel for breathing” was used to
response system after finding an unresponsive victim. The assess breathing after the airway was opened.
provider then returned to the victim and opened the airway and
checked for breathing or abnormal breathing.
Why: With the new chest compression–first sequence, CPR is
performed if the adult victim is unresponsive and not breathing
Why: The healthcare provider should not delay activation of or not breathing normally (ie, not breathing or only gasping)
the emergency response system but should obtain 2 pieces of and begins with compressions (C-A-B sequence). Therefore,
information simultaneously: the provider should check the victim breathing is briefly checked as part of a check for cardiac
for response and check for no breathing or no normal breathing. arrest. After the first set of chest compressions, the airway is
If the victim is unresponsive and is not breathing at all or has no opened and the rescuer delivers 2 breaths.
normal breathing (ie, only agonal gasps), the provider should
activate the emergency response system and retrieve the AED if Chest Compression Rate: At Least 100 per Minute*
available (or send someone to do so). If the healthcare provider
does not feel a pulse within 10 seconds, the provider should 2010 (New): It is reasonable for lay rescuers and healthcare
begin CPR and use the AED when it is available. providers to perform chest compressions at a rate of at least
100/min.
Change in CPR Sequence: C-A-B Rather
Than A-B-C* 2005 (Old): Compress at a rate of about 100/min.
Why: The number of chest compressions delivered per
2010 (New): A change in the 2010 AHA Guidelines for CPR minute during CPR is an important determinant of ROSC and
and ECC is to recommend the initiation of chest compressions survival with good neurologic function. The actual number of
before ventilations. chest compressions delivered per minute is determined by the
rate of chest compressions and the number and duration of
2005 (Old): The sequence of adult CPR began with opening
interruptions in compressions (eg, to open the airway, deliver
of the airway, checking for normal breathing, and then delivering
rescue breaths, or allow AED analysis). In most studies, delivery
2 rescue breaths followed by cycles of 30 chest compressions
of more compressions during resuscitation is associated with
and 2 breaths.
better survival, and delivery of fewer compressions is associated
Why: Although no published human or animal evidence with lower survival. Provision of adequate chest compressions
demonstrates that starting CPR with 30 compressions requires an emphasis not only on an adequate compression rate
rather than 2 ventilations leads to improved outcome, chest but also on minimizing interruptions to this critical component of
compressions provide the blood flow, and studies of out-of- CPR. An inadequate compression rate or frequent interruptions
hospital adult cardiac arrest showed that survival was higher (or both) will reduce the total number of compressions delivered
when bystanders provided chest compressions rather than no per minute. For further information, see Box 2 on page 4.
chest compressions. Animal data demonstrate that delays or
interruptions in chest compressions reduce survival, so such
Chest Compression Depth*
delays and interruptions should be minimized throughout the
entire resuscitation. Chest compressions can be started almost 2010 (New): The adult sternum should be depressed at least 2
immediately, whereas positioning the head and achieving a inches (5 cm).
seal for mouth-to-mouth or bag-mask rescue breathing all take
2005 (Old): The adult sternum should be depressed 1½ to 2
time. The delay in initiation of compressions can be reduced if 2
inches (approximately 4 to 5 cm).
rescuers are present: the first rescuer begins chest compressions,
and the second rescuer opens the airway and is prepared to Why: Compressions create blood flow primarily by increasing
deliver breaths as soon as the first rescuer has completed the intrathoracic pressure and directly compressing the heart.
first set of 30 chest compressions. Whether 1 or more rescuers Compressions generate critical blood flow and oxygen and
are present, initiation of CPR with chest compressions ensures energy delivery to the heart and brain. Confusion may result
that the victim receives this critical intervention early. when a range of depth is recommended, so 1 compression
depth is now recommended. Rescuers often do not adequately
Elimination of “Look, Listen, and Feel compress the chest despite recommendations to “push hard.”
for Breathing”* In addition, the available science suggests that compressions
of at least 2 inches are more effective than compressions
2010 (New): “Look, listen, and feel for breathing” was of 1½ inches. For this reason the 2010 AHA Guidelines for CPR
removed from the sequence for assessment of breathing after and ECC recommend a single minimum depth for compression
opening the airway. The healthcare provider briefly checks of the adult chest, and that compression depth is deeper than
for breathing when checking responsiveness to detect signs in the old recommendation.
H i g h l i g h t s o f t h e 2 0 1 0 A H A G u i d e l i n e s f o r C PR and ECC 7
10. H E A LT H C A R E P R O V I D E R B L S
Table 1
Summary of Key BLS Components for Adults, Children, and Infants*
Recommendations
Component Adults Children Infants
Unresponsive (for all ages)
No breathing or no normal
Recognition No breathing or only gasping
breathing (ie, only gasping)
No pulse palpated within 10 seconds for all ages (HCP only)
CPR sequence C-A-B
Compression rate At least 100/min
At least ¹⁄³ AP diameter At least ¹⁄³ AP diameter
Compression depth At least 2 inches (5 cm)
About 2 inches (5 cm) About 1½ inches (4 cm)
Allow complete recoil between compressions
Chest wall recoil
HCPs rotate compressors every 2 minutes
Minimize interruptions in chest compressions
Compression interruptions
Attempt to limit interrruptions to <10 seconds
Airway Head tilt–chin lift (HCP suspected trauma: jaw thrust)
30:2
Compression-to-ventilation Single rescuer
30:2
ratio (until advanced
1 or 2 rescuers
airway placed) 15:2
2 HCP rescuers
Ventilations: when rescuer
untrained or trained and Compressions only
not proficient
1 breath every 6-8 seconds (8-10 breaths/min)
Ventilations with advanced Asynchronous with chest compressions
airway (HCP) About 1 second per breath
Visible chest rise
Attach and use AED as soon as available. Minimize interruptions in chest compressions before and after shock;
Defibrillation
resume CPR beginning with compressions immediately after each shock.
Abbreviations: AED, automated external defibrillator; AP, anterior-posterior; CPR, cardiopulmonary resuscitation; HCP, healthcare provider.
*Excluding the newly born, in whom the etiology of an arrest is nearly always asphyxial.
Team Resuscitation Why: Some resuscitations start with a lone rescuer who
calls for help, whereas other resuscitations begin with several
2010 (New): The steps in the BLS algorithm have traditionally willing rescuers. Training should focus on building a team
been presented as a sequence to help a single rescuer as each rescuer arrives, or on designating a team leader if
prioritize actions. There is increased focus on providing multiple rescuers are present. As additional personnel arrive,
CPR as a team because resuscitations in most EMS and responsibilities for tasks that would ordinarily be performed
healthcare systems involve teams of rescuers, with rescuers sequentially by fewer rescuers may now be delegated to a team
performing several actions simultaneously. For example, one of providers who perform them simultaneously. For this reason,
rescuer activates the emergency response system while a BLS healthcare provider training should not only teach individual
second begins chest compressions, a third is either providing skills but should also teach rescuers to work in effective teams.
ventilations or retrieving the bag-mask for rescue breathing,
Comparison of Key Elements of Adult, Child,
and a fourth is retrieving and setting up a defibrillator.
and Infant BLS
2005 (Old): The steps of BLS consist of a series of sequential
assessments and actions. The intent of the algorithm is to As in the 2005 AHA Guidelines for CPR and ECC, the 2010 AHA
present the steps in a logical and concise manner that will be Guidelines for CPR and ECC contain a comparison table that lists
easy for each rescuer to learn, remember, and perform. the key elements of adult, child, and infant BLS (excluding CPR for
newly born infants). These key elements are included in Table 1.
8 American Heart Association
11. ELECTRICAL THERAPIES
ELECTRICAL • A planned and practiced response, typically requiring
oversight by a healthcare provider
THERAPIES
• Training of anticipated rescuers in CPR and use of the AED
The 2010 AHA Guidelines for CPR and ECC have been • A link with the local EMS system
updated to reflect new data regarding defibrillation and • A program of ongoing quality improvement
cardioversion for cardiac rhythm disturbances and the use of
pacing in bradycardia. These data largely continue to support There is insufficient evidence to recommend for or against the
the recommendations in the 2005 AHA Guidelines for CPR deployment of AEDs in homes.
and ECC. Therefore, no major changes were recommended
In-Hospital Use of AEDs
regarding defibrillation, cardioversion, and pacing. Emphasis on
early defibrillation integrated with high-quality CPR is the key to 2010 (Reaffirmed 2005 Recommendation): Despite
improving survival from sudden cardiac arrest. limited evidence, AEDs may be considered for the hospital
setting as a way to facilitate early defibrillation (a goal of shock
Summary of Key Issues and Major Changes delivery ≤3 minutes from collapse), especially in areas where
staff have no rhythm recognition skills or defibrillators are used
Main topics include infrequently. Hospitals should monitor collapse-to–first shock
intervals and resuscitation outcomes.
• Integration of AEDs into the Chain of Survival system for
public places AED Use in Children Now Includes Infants
• Consideration of AED use in hospitals 2010 (New): For attempted defibrillation of children 1 to 8
years of age with an AED, the rescuer should use a pediatric
• AEDs can now be used in infants if a manual defibrillator is dose-attenuator system if one is available. If the rescuer
not available provides CPR to a child in cardiac arrest and does not have an
• Shock first versus CPR first in cardiac arrest AED with a pediatric dose-attenuator system, the rescuer should
use a standard AED. For infants (<1 year of age), a manual
• 1-shock protocol versus 3-shock sequence for VF defibrillator is preferred. If a manual defibrillator is not available,
an AED with pediatric dose attenuation is desirable. If neither is
• Biphasic and monophasic waveforms
available, an AED without a dose attenuator may be used.
• Escalating versus fixed doses for second and
subsequent shocks
2005 (Old): For children 1 to 8 years of age, the rescuer
should use a pediatric dose-attenuator system if one is
• Electrode placement available. If the rescuer provides CPR to a child in cardiac
arrest and does not have an AED with a pediatric attenuator
• External defibrillation with implantable
system, the rescuer should use a standard AED. There are
cardioverter-defibrillator
insufficient data to make a recommendation for or against the
• Synchronized cardioversion use of AEDs for infants <1 year of age.
Why: The lowest energy dose for effective defibrillation in
Automated External Defibrillators infants and children is not known. The upper limit for safe
defibrillation is also not known, but doses >4 J/kg (as high
Community Lay Rescuer AED Programs as 9 J/kg) have effectively defibrillated children and animal
2010 (Slightly Modified): Cardiopulmonary resuscitation models of pediatric arrest with no significant adverse effects.
and the use of AEDs by public safety first responders are Automated external defibrillators with relatively high-energy
recommended to increase survival rates for out-of-hospital doses have been used successfully in infants in cardiac arrest
sudden cardiac arrest. The 2010 AHA Guidelines for CPR and with no clear adverse effects.
ECC again recommend the establishment of AED programs Shock First vs CPR First
in public locations where there is a relatively high likelihood of
witnessed cardiac arrest (eg, airports, casinos, sports facilities).
2010 (Reaffirmed 2005 Recommendation): When any
To maximize the effectiveness of these programs, the AHA
rescuer witnesses an out-of-hospital arrest and an AED is
continues to emphasize the importance of organizing, planning,
immediately available on-site, the rescuer should start CPR
training, linking with the EMS system, and establishing a
with chest compressions and use the AED as soon as possible.
process of continuous quality improvement.
Healthcare providers who treat cardiac arrest in hospitals and
2005 (Old): The 2005 AHA Guidelines for CPR and ECC other facilities with on-site AEDs or defibrillators should provide
identified 4 components for successful community lay rescuer immediate CPR and should use the AED/defibrillator as soon
AED programs: as it is available. These recommendations are designed to
H i g h l i g h t s o f t h e 2 0 1 0 A H A G u i d e l i n e s f o r C PR and ECC 9
12. ELECTRICAL THERAPIES
support early CPR and early defibrillation, particularly when an Defibrillation Waveforms and Energy Levels
AED or defibrillator is available within moments of the onset of
sudden cardiac arrest. When an out-of-hospital cardiac arrest is 2010 (No Change From 2005): Data from both out-
not witnessed by EMS personnel, EMS may initiate CPR while of-hospital and in-hospital studies indicate that biphasic
checking the rhythm with the AED or on the electrocardiogram waveform shocks at energy settings comparable to or lower
(ECG) and preparing for defibrillation. In such instances, 1½ than 200-J monophasic shocks have equivalent or higher
to 3 minutes of CPR may be considered before attempted success for termination of VF. However, the optimal energy
defibrillation. Whenever 2 or more rescuers are present, CPR for first-shock biphasic waveform defibrillation has not been
should be provided while the defibrillator is retrieved. determined. Likewise, no specific waveform characteristic
With in-hospital sudden cardiac arrest, there is insufficient (either monophasic or biphasic) is consistently associated with
evidence to support or refute CPR before defibrillation. a greater incidence of ROSC or survival to hospital discharge
However, in monitored patients, the time from VF to shock after cardiac arrest.
delivery should be under 3 minutes, and CPR should be In the absence of biphasic defibrillators, monophasic
performed while the defibrillator is readied. defibrillators are acceptable. Biphasic waveform shock
Why: When VF is present for more than a few minutes, the configurations differ among manufacturers, and none have
myocardium is depleted of oxygen and energy. A brief period been directly compared in humans with regard to their
of chest compressions can deliver oxygen and energy to the relative efficacy. Because of such differences in waveform
heart, increasing the likelihood that a shock will both eliminate configuration, providers should use the manufacturer’s
VF (defibrillation) and be followed by ROSC. Before the recommended energy dose (120 to 200 J) for its respective
publication of the 2005 AHA Guidelines for CPR and ECC, waveform. If the manufacturer’s recommended dose is not
2 studies suggested the potential benefit of CPR first rather known, defibrillation at the maximal dose may be considered.
than shock first. In both studies, although 1½ to 3 minutes of
Pediatric Defibrillation
CPR before shock delivery did not improve overall survival from
VF, the CPR-first strategy did improve survival among victims 2010 (Modification of Previous Recommendation): For
with VF if the EMS call-to-arrival interval was 4 to 5 minutes pediatric patients, the optimal defibrillation dose is unknown.
or longer. However, 2 subsequent randomized controlled There are limited data regarding the lowest effective dose or the
trials found that CPR before attempted defibrillation by EMS upper limit for safe defibrillation. A dose of 2 to 4 J/kg may be
personnel was not associated with a significant difference used for the initial defibrillation energy, but for ease of teaching,
in survival to discharge. One retrospective study did find an an initial dose of 2 J/kg may be considered. For subsequent
improved neurologic status at 30 days and at 1 year when shocks, energy levels should be at least 4 J/kg; higher energy
immediate CPR was compared with immediate defibrillation in levels may be considered, not to exceed 10 J/kg or the adult
patients with out-of-hospital VF. maximum dose.
1-Shock Protocol vs 3-Shock Sequence 2005 (Old): The initial dose for attempted defibrillation for
infants and children when using a monophasic or biphasic
manual defibrillator is 2 J/kg. The second and subsequent
2010 (No Change From 2005): At the time of the
doses are 4 J/kg.
International Liaison Committee on Resuscitation (ILCOR) 2010
International Consensus Conference on CPR and ECC Science Why: There are insufficient data to make a substantial change
With Treatment Recommendations, 2 new published human in the existing recommended doses for pediatric defibrillation.
studies compared a 1-shock protocol versus a 3-stacked- Initial doses of 2 J/kg with monophasic waveforms are effective
shock protocol for treatment of VF cardiac arrest. Evidence in terminating 18% to 50% of VF cases, with insufficient
from these 2 studies suggests significant survival benefit with a evidence to compare the success of higher doses. Case
single-shock defibrillation protocol compared with a 3-stacked- reports document successful defibrillation at doses up to 9 J/kg
shock protocol. If 1 shock fails to eliminate VF, the incremental with no adverse effects detected. More data are needed.
benefit of another shock is low, and resumption of CPR is likely
to confer a greater value than another immediate shock. This Fixed and Escalating Energy
fact, combined with the data from animal studies documenting 2010 (No Change From 2005): The optimal biphasic
harmful effects from interruptions to chest compressions energy level for first or subsequent shocks has not been
and human studies suggesting a survival benefit from a CPR determined. Therefore, it is not possible to make a definitive
approach that includes a 1-shock compared with a 3-shock recommendation for the selected energy for subsequent
protocol, supports the recommendation of single shocks biphasic defibrillation attempts. On the basis of available
followed by immediate CPR rather than stacked shocks for evidence, if the initial biphasic shock is unsuccessful in
attempted defibrillation.
10 American Heart Association
13. ELECTRICAL THERAPIES
terminating VF, subsequent energy levels should be at least may prevent VF detection (and therefore shock delivery). The
equivalent, and higher energy levels may be considered, key message to rescuers is that concern about precise pad or
if available. paddle placement in relation to an implanted medical device
should not delay attempted defibrillation.
Electrode Placement
Synchronized Cardioversion
2010 (Modification of Previous Recommendation):
For ease of placement and education, the anterior-lateral pad Supraventricular Tachyarrhythmia
position is a reasonable default electrode placement. Any
2010 (New): The recommended initial biphasic energy dose
of 3 alternative pad positions (anterior-posterior, anterior–
for cardioversion of atrial fibrillation is 120 to 200 J. The initial
left infrascapular, and anterior–right infrascapular) may be
monophasic dose for cardioversion of atrial fibrillation is 200 J.
considered on the basis of individual patient characteristics.
Cardioversion of adult atrial flutter and other supraventricular
Placement of AED electrode pads on the victim’s bare chest in
rhythms generally requires less energy; an initial energy of
any of the 4 pad positions is reasonable for defibrillation.
50 to 100 J with either a monophasic or a biphasic device is
2005 (Old): Rescuers should place AED electrode pads on the often sufficient. If the initial cardioversion shock fails, providers
victim’s bare chest in the conventional sternal-apical (anterior- should increase the dose in a stepwise fashion.
lateral) position. The right (sternal) chest pad is placed on the
2005 (Old): The recommended initial monophasic energy
victim’s right superior-anterior (infraclavicular) chest, and the
dose for cardioversion of atrial fibrillation is 100 to 200 J.
apical (left) pad is placed on the victim’s inferior-lateral left
Cardioversion with biphasic waveforms is now available, but
chest, lateral to the left breast. Other acceptable pad positions
the optimal doses for cardioversion with biphasic waveforms
are placement on the lateral chest wall on the right and left
have not been established with certainty. Extrapolation from
sides (biaxillary) or the left pad in the standard apical position
published experience with elective cardioversion of atrial
and the other pad on the right or left upper back.
fibrillation with the use of rectilinear and truncated exponential
Why: New data demonstrate that the 4 pad positions waveforms supports an initial dose of 100 to 120 J with
(anterior-lateral, anterior-posterior, anterior–left infrascapular, escalation as needed. This initial dose has been shown to
and anterior–right infrascapular) appear to be equally effective be 80% to 85% effective in terminating atrial fibrillation. Until
to treat atrial or ventricular arrhythmias. Again, for ease of further evidence becomes available, this information can be
teaching, the default position taught in AHA courses will not used to extrapolate biphasic cardioversion doses to other
change from the 2005 recommended position. No studies tachyarrhythmias.
were identified that directly evaluated the effect of placement
Why: The writing group reviewed interim data on all biphasic
of pads or paddles on defibrillation success with the endpoint
studies conducted since the 2005 AHA Guidelines for CPR
of ROSC.
and ECC were published and made minor changes to update
Defibrillation With Implantable cardioversion dose recommendations. A number of studies
attest to the efficacy of biphasic waveform cardioversion
Cardioverter-Defibrillator
of atrial fibrillation with energy settings from 120 to 200 J,
2010 (New): The anterior-posterior and anterior-lateral depending on the specific waveform.
locations are generally acceptable in patients with implanted
pacemakers and defibrillators. In patients with implantable Ventricular Tachycardia
cardioverter-defibrillators or pacemakers, pad or paddle 2010 (New): Adult stable monomorphic VT responds well to
placement should not delay defibrillation. It might be monophasic or biphasic waveform cardioversion (synchronized)
reasonable to avoid placing the pads or paddles directly over shocks at initial energies of 100 J. If there is no response to the
the implanted device. first shock, it may be reasonable to increase the dose in a step-
2005 (Old): When an implantable medical device is located wise fashion. No interim studies were found that addressed this
in an area where a pad would normally be placed, position the rhythm, so the recommendations were made by writing group
pad at least 1 inch (2.5 cm) away from the device. expert consensus.
Why: The language of this recommendation is a bit softer Synchronized cardioversion must not be used for treatment
than the language used in 2005. There is the potential for of VF because the device is unlikely to sense a QRS wave,
pacemaker or implantable cardioverter-defibrillator malfunction and thus, a shock may not be delivered. Synchronized
after defibrillation when the pads are in close proximity to cardioversion should also not be used for pulseless VT or
the device. One study with cardioversion demonstrated that polymorphic VT (irregular VT).These rhythms require delivery of
positioning the pads at least 8 cm away from the device did high-energy unsynchronized shocks (ie, defibrillation doses).
not damage device pacing, sensing, or capturing. Pacemaker
spikes with unipolar pacing may confuse AED software and
H i g h l i g h t s o f t h e 2 0 1 0 A H A G u i d e l i n e s f o r C PR and ECC 11
14. CPR TECHNIQUES AND DEVICES
2005 (Old): There was insufficient evidence to recommend a may improve hemodynamics or short-term survival when
biphasic dose for cardioversion of monomorphic VT. The 2005 used by well-trained providers in selected patients.
AHA Guidelines for CPR and ECC recommended use of an
2010 (New): The precordial thump should not be used for
unsynchronized shock for treatment of the unstable patient
unwitnessed out-of-hospital cardiac arrest. The precordial
with polymorphic VT.
thump may be considered for patients with witnessed,
Why: The writing group agreed that it would be helpful to add monitored, unstable VT (including pulseless VT) if a defibrillator
a biphasic dose recommendation to the 2010 AHA Guidelines is not immediately ready for use, but it should not delay CPR
for CPR and ECC for cardioversion of monomorphic VT but and shock delivery.
wanted to emphasize the need to treat polymorphic VT as
2005 (Old): No recommendation was provided previously.
unstable and as an arrest rhythm.
Why: A precordial thump has been reported to convert
Fibrillation Waveform Analysis to
ventricular tachyarrhythmias in some studies. However,
Predict Outcome 2 larger case series found that the precordial thump did
not result in ROSC for cases of VF. Reported complications
2010 (No Change From 2005): The value of VF waveform associated with precordial thump include sternal fracture,
analysis to guide defibrillation management during resuscitation osteomyelitis, stroke, and triggering of malignant arrhythmias
is uncertain. in adults and children. The precordial thump should not delay
initiation of CPR or defibrillation.
Pacing
CPR Devices
2010 (No Change From 2005): Pacing is not routinely
recommended for patients in asystolic cardiac arrest. In Several mechanical CPR devices have been the focus of
patients with symptomatic bradycardia with a pulse, it is recent clinical trials. Initiation of therapy with these devices (ie,
reasonable for healthcare providers to be prepared to initiate application and positioning of the device) has the potential
transcutaneous pacing in patients who do not respond to to delay or interrupt CPR for the victim of cardiac arrest, so
drugs. If transcutaneous pacing fails, transvenous pacing rescuers should be trained to minimize any interruption of
initiated by a trained provider with experience in central chest compressions or defibrillation and should be retrained
venous access and intracardiac pacing is probably indicated. as needed.
Use of the impedance threshold device improved ROSC
and short-term survival in adults with out-of-hospital cardiac
CPR TECHNIQUES AND DEVICES arrest, but it has not improved long-term survival in patients
with cardiac arrest.
Summary of Key Issues and Major Changes One multicenter, prospective, randomized controlled trial
comparing load-distributing band CPR (AutoPulse®) with
manual CPR for out-of-hospital cardiac arrest demonstrated
To date, no CPR device has consistently been shown to be
no improvement in 4-hour survival and worse neurologic
superior to standard conventional (manual) CPR for out-of-
outcome when the device was used. Further studies are
hospital BLS, and no device other than a defibrillator has
required to determine if site-specific factors and experience
consistently improved long-term survival from out-of-hospital
with deployment of the device could influence its efficacy.
cardiac arrest. This part of the 2010 AHA Guidelines for CPR
There is insufficient evidence to support the routine use of
and ECC does contain summaries of recent clinical trials.
this device.
CPR Techniques Case series employing mechanical piston devices have
reported variable degrees of success. Such devices may be
Alternatives to conventional manual CPR have been considered for use when conventional CPR would be difficult
developed in an effort to enhance perfusion during to maintain (eg, during diagnostic studies).
resuscitation from cardiac arrest and to improve survival.
Compared with conventional CPR, these techniques typically To prevent delays and maximize efficiency, initial training,
require more personnel, training, and equipment, or they ongoing monitoring, and retraining programs should be
apply to a specific setting. Some alternative CPR techniques offered on a frequent basis to providers using CPR devices.
12 American Heart Association
15. ACLS
ADVANCED CARDIOVASCULAR • Chronotropic drug infusions are recommended as an
alternative to pacing in symptomatic and unstable bradycardia.
LIFE SUPPORT
• Adenosine is recommended as safe and potentially
effective for both treatment and diagnosis in the initial
Summary of Key Issues and Major Changes management of undifferentiated regular monomorphic wide-
complex tachycardia.
The major changes in advanced cardiovascular life support
• Systematic post–cardiac arrest care after ROSC should
(ACLS) for 2010 include the following:
continue in a critical care unit with expert multidisciplinary
• Quantitative waveform capnography is recommended for management and assessment of the neurologic and
confirmation and monitoring of endotracheal tube placement physiologic status of the patient. This often includes the use
and CPR quality. of therapeutic hypothermia.
• The traditional cardiac arrest algorithm was simplified and an
Capnography Recommendation
alternative conceptual design was created to emphasize the
importance of high-quality CPR.
2010 (New): Continuous quantitative waveform capnography
• There is an increased emphasis on physiologic monitoring to is now recommended for intubated patients throughout the
optimize CPR quality and detect ROSC. periarrest period. When quantitative waveform capnography
is used for adults, applications now include recommendations
• Atropine is no longer recommended for routine use in the
for confirming tracheal tube placement and for monitoring CPR
management of pulseless electrical activity (PEA)/asystole.
quality and detecting ROSC based on end-tidal carbon dioxide
(PETCO2) values (Figures 3A and 3B).
Figure 3
Capnography Waveforms
1-minute interval
50
mm Hg
37.5
25
12.5
0
Before intubation Intubated
A.
Capnography to confirm endotracheal tube placement. This capnography tracing displays the partial pressure of exhaled carbon dioxide
(PETCO2) in mm Hg on the vertical axis over time when intubation is performed. Once the patient is intubated, exhaled carbon dioxide is detected,
confirming tracheal tube placement. The PETCO2 varies during the respiratory cycle, with highest values at end-expiration.
1-minute interval
50
mm Hg
37.5
25
12.5
0
CPR ROSC
B.
Capnography to monitor effectiveness of resuscitation efforts. This second capnography tracing displays the PETCO2 in mm Hg on the
vertical axis over time. This patient is intubated and receiving CPR. Note that the ventilation rate is approximately 8 to 10 breaths per minute.
Chest compressions are given continuously at a rate of slightly faster than 100/min but are not visible with this tracing. The initial PETCO2
is less than 12.5 mm Hg during the first minute, indicating very low blood flow. The PETCO2 increases to between 12.5 and 25 mm Hg during
the second and third minutes, consistent with the increase in blood flow with ongoing resuscitation. Return of spontaneous circulation (ROSC)
occurs during the fourth minute. ROSC is recognized by the abrupt increase in the PETCO2 (visible just after the fourth vertical line) to over
40 mm Hg, which is consistent with a substantial improvement in blood flow.
H i g h l i g h t s o f t h e 2 0 1 0 A H A G u i d e l i n e s f o r C PR and ECC 13
16. ACLS
Figure 4
Circular ACLS Algorithm
Adult Cardiac Arrest CPR Quality
• ush hard (≥2 inches [5 cm]) and fast (≥100/min) and allow complete
P
chest recoil
• inimize interruptions in compressions
M
Shout for Help/Activate Emergency Response • void excessive ventilation
A
• otate compressor every 2 minutes
R
• f no advanced airway, 30:2 compression-ventilation ratio
I
• uantitative waveform capnography
Q
Start CPR – f Petco2 <10 mm Hg, attempt to improve CPR quality
I
• Give oxygen
• ntra-arterial pressure
I
• Attach monitor/defibrillator
– f relaxation phase (diastolic) pressure <20 mm Hg, attempt to
I
Return of Spontaneous improve CPR quality
2 minutes Circulation (ROSC) Return of Spontaneous Circulation (ROSC)
• ulse and blood pressure
P
Check Post–Cardiac • brupt sustained increase in Petco2 (typically ≥40 mm Hg)
A
Rhythm Arrest Care • pontaneous arterial pressure waves with intra-arterial monitoring
S
If VF/VT
Shock Shock Energy
• Biphasic: Manufacturer recommendation (120-200 J); if unknown,
Drug Therapy use maximum available. Second and subsequent doses should be
equivalent, and higher doses may be considered.
tinuous CPR
IV/IO access
Co
Epinephrine every 3-5 minutes • Monophasic: 360 J
ntinu us CPR
Amiodarone for refractory VF/VT Drug Therapy
• Epinephrine IV/IO Dose: 1 mg every 3-5 minutes
• asopressin IV/IO Dose: 40 units can replace first or second dose
V
o
Consider Advanced Airway of epinephrine
Quantitative waveform capnography
• Amiodarone IV/IO Dose: First dose: 300 mg bolus. Second dose: 150 mg.
on
Advanced Airway
• upraglottic advanced airway or endotracheal intubation
S
C
Treat Reversible Causes • aveform capnography to confirm and monitor ET tube placement
W
• -10 breaths per minute with continuous chest compressions
8
Mo y
n it o r C R Q u a lit
Reversible Causes
– Hypovolemia – Tension pneumothorax
P – Hypoxia – Tamponade, cardiac
– Hydrogen ion (acidosis) – Toxins
– Hypo-/hyperkalemia – Thrombosis, pulmonary
– Hypothermia – Thrombosis, coronary
2005 (Old): An exhaled carbon dioxide (CO2) detector or an in the patient with ROSC also causes a decrease in PETCO2. In
esophageal detector device was recommended to confirm contrast, ROSC may cause an abrupt increase in PETCO2.
endotracheal tube placement. The 2005 AHA Guidelines for
CPR and ECC noted that PETCO2 monitoring can be useful as a Simplified ACLS Algorithm and New Algorithm
noninvasive indicator of cardiac output generated during CPR.
2010 (New): The conventional ACLS Cardiac Arrest
Why: Continuous waveform capnography is the most reliable Algorithm has been simplified and streamlined to emphasize
method of confirming and monitoring correct placement of the importance of high-quality CPR (including compressions
an endotracheal tube. Although other means of confirming of adequate rate and depth, allowing complete chest recoil
endotracheal tube placement are available, they are not more after each compression, minimizing interruptions in chest
reliable than continuous waveform capnography. Patients are compressions, and avoiding excessive ventilation) and the fact
at increased risk of endotracheal tube displacement during that ACLS actions should be organized around uninterrupted
transport or transfer; providers should observe a persistent periods of CPR. A new circular algorithm is also introduced
capnographic waveform with ventilation to confirm and monitor (Figure 4, above).
endotracheal tube placement.
2005 (Old): The same priorities were cited in the 2005 AHA
Because blood must circulate through the lungs for CO2 to Guidelines for CPR and ECC. The box and arrow algorithm
be exhaled and measured, capnography can also serve as a listed key actions performed during the resuscitation in a
physiologic monitor of the effectiveness of chest compressions sequential fashion.
and to detect ROSC. Ineffective chest compressions (due
to either patient characteristics or rescuer performance) are Why: For the treatment of cardiac arrest, ACLS interventions
associated with a low PETCO2. Falling cardiac output or rearrest build on the BLS foundation of high-quality CPR to increase
14 American Heart Association