The document provides an introduction to medical informatics presented by Aslı Yazağan. It discusses the history of applying mathematics concepts like statistics and probability to social sciences including medicine. It also outlines emerging trends in medical fields like genomic medicine and electronic health records. New technologies being applied to medicine are reviewed like wearable devices, 3D printing, and virtual/augmented reality.

1. Introduction to Medical Informatics
Aslı YAZAĞAN
Middle East Technical University
Doctoral Student at
Informatic Institute
Medical Informatics Programme
&
RTEU Vocational School
Teaching Assistant at
Computer Technologies Department
31.03.2015 Tbilisi State Medical University Aslı Yazağan

2. Who I am
31.03.2015 Tbilisi State Medical University Aslı Yazağan
Matematics @ Hacettepe
Informatics @ Pittsburgh
Medical Informatics Metu

3. Overview
Story of Mathematics and Statistics
Medical Informatics
 Global Health Issues
Emerging Trends
 The Future of Medicine
New Technologies in Medicine
Wearable & Portable Health Devices
3D Printing
Augmented Reality
Online Health Communities
INTRODUCTION TO MEDICAL INFORMATICS
31.03.2015 Tbilisi State Medical University Aslı Yazağan

4. Chain Problem
INTRODUCTION TO MEDICAL INFORMATICS
31.03.2015 Tbilisi State Medical University Aslı Yazağan
Here is the story
What do you
think about
this?

5. Chain Problem
INTRODUCTION TO MEDICAL INFORMATICS
31.03.2015 Tbilisi State Medical University Aslı Yazağan
What about
this?

6. Turbulance Theory
Newton (17.yy) vs. Laplace (18.yy)
INTRODUCTION TO MEDICAL INFORMATICS
31.03.2015 Tbilisi State Medical University Aslı Yazağan

7. Math : Language of Nature
• Math create rules to define the whole universe.
• Is it possible to apply mathematics’s principles on
social sciences such as biology, sociology, economic
and medicine?
• Is it language for human nature?
INTRODUCTION TO MEDICAL INFORMATICS
31.03.2015 Tbilisi State Medical University Aslı Yazağan

8. Dealing with uncertanity
• Human ~ Uncertanity, many variables..
• Not possible to have exact result.
• How to calculate the probability of a case occurs?
 Statistics and Probability
• 16yy : researchers tries to deal with uncertanity.
Kuantum Physics rely on uncertanity.
INTRODUCTION TO MEDICAL INFORMATICS
31.03.2015 Tbilisi State Medical University Aslı Yazağan

9. Mathematics
use statistics and probability to diffuse
social sciences.
INTRODUCTION TO MEDICAL INFORMATICS
31.03.2015 Tbilisi State Medical University Aslı Yazağan
Social Sciences
(biology,
sociology,
economics
medicine)
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10. Statistics
• 17.yy - a salesclerk in London : John Graunt
• Weekly Death Report from all regions > Live table
 63 disease and death reasons
 First time new born sex balance
 Age distibution of people in the region
 Child and old deaths and reasons
• Mathematics meet with Social Sciences…
INTRODUCTION TO MEDICAL INFORMATICS
31.03.2015 Tbilisi State Medical University Aslı Yazağan

11. Statistics
• If a person 60 years old what is the prob. of he lives
until 80?
• Even papa used!
“According to table half of people die before 17 years old. So
instead of complaining about life, we should think each year a
gift for us given.” Edmont Halley
INTRODUCTION TO MEDICAL INFORMATICS
31.03.2015 Tbilisi State Medical University Aslı Yazağan

12. Statistics
• Social phenomenon has a reason and statistics can
be used to set rules for social regulation.
• Founder of modern statistics: Belguim scientist
Lambert Adolphe-Jacques Quetelet
• People’s weight, height, limb lenght and also
entellectual properties…
All human features has similar distibution.
INTRODUCTION TO MEDICAL INFORMATICS
31.03.2015 Tbilisi State Medical University Aslı Yazağan

13. Statistics
• Measurable features has a distribution depending
a mathematical function.
• But people income does not show a normal
distribution??
INTRODUCTION TO MEDICAL INFORMATICS
31.03.2015 Tbilisi State Medical University Aslı Yazağan

14. Probability
• Gamblers..
• Karl Peason
 24.000 coin toss : 12.000 vs 12.012
INTRODUCTION TO MEDICAL INFORMATICS
31.03.2015 Tbilisi State Medical University Aslı Yazağan
“Looks like a chance but it obeys a rule”.

15. Probability and Genetics
• A priest from Moravia : Mendel
• Mathematicals foundation of Genetics
• Experiments on peas
Similar to 2 coin toss experiment.
INTRODUCTION TO MEDICAL INFORMATICS
31.03.2015 Tbilisi State Medical University Aslı Yazağan

16. Next Generation Sequencing
• Geneticists tries to predicts future
generation characteristics analyzing DNA
using statisicical methods.
INTRODUCTION TO MEDICAL INFORMATICS
31.03.2015 Tbilisi State Medical University Aslı Yazağan

17. Big Data
• Probability and Statistics are meaningfull
if
there is a BIG AMOUNT OF DATA
Informatics
INTRODUCTION TO MEDICAL INFORMATICS
31.03.2015 Tbilisi State Medical University Aslı Yazağan

18. The world is getting old… Demand is increasing…
 The life expectancy of human is increasing
 Chronic diseases is increasing
 Health Personnel need is increasing
 Health consciousness is improving
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

21. +
Hospitals need
Qualified Health workers need
Increasing Health Expenses and gap between rich & poor
Insufficient education of public
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

22. 31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

23. Emerging Trends in Medical Field
Genomic Medicine
Standardized Electronic Health Records
Remote Healthcare and Diagnosis
Aggregated Public Health Data
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

24. Genomic Medicine
• Advances in genomic medicine envision personalized
medicine that uses individuals’ genome information to
prevent, diagnose and treat diseases.
Challenges: storing, sharing and analyzing the genomic data.
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

25. Electronic Health Records
• Electronic Health Record (EHR) is a longitutudinal
electronic record of patient health information
generated by one or more encounters in any care
delivery setting.
Challenges: Storing, sharing and analyzing it securely.
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

26. Remote Healthcare and Diagnosis
• Solution for the people that are not able to get
good health services in rural areas.
• Health Professionals can collaborate to give the
best decision for patients.
• Patients can be monitored to get real-time health
information using a mobile device and an alarm
system can be triggered when an abnormal
situation is detected.
Challenges: Storing, sharing and analyzing it securely.
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

27. Aggregated Public Health Data
• Large data obtained by digital health records that
does not have information identifies any individual
patients.
Challenges: Analyzing this data can produce significant
outcomes for public assessments, public education and
for commercial purposes.
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

28. What are the NEEDs for Future?
Clinicians need to;
Be more efficient
Migrate away from paper based-records
Reduce Medication errors
Have educational and patient related information at their
fingerprints.
More tools for clinicians;
Internet
High speed computers
Voice recognition
Wireless and mobile technology
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

29. A Geek Doctor
Bertalan Meskó, MD, PhD
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

30. Preventive Medicine
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

31. 31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

32. Medicine + Mathematics + Engineering
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

33. Medicine + Mathematics + Engineering
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

34. 31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

35. What could be a Solution?
•Application of computers, communications and information
technology and systems to all field of medicine – medical care,
medical education and medical research.
•Use scientific field that deals with big data.
•Understanding, skills and tools that enable the sharing and use
of information to deliver healthcare and promote health
Doctor 2.0
•Bioinformatics
Analysis of biological information using computers and
statistical techniques; the science of developing and utilizing
computer databases and algorithms to accelerate and enhance
biological research.
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

36. Medicine + Mathematics + Engineering + Informatics
Medicine : grounds us in clinically relevent questions
Mathematics : news way to analyze and taylor it to specific disease
Engineering : put the pieces together
Informatics: helps to deal with big data
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

37. Medical Informatics
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS
Medicine is going to become an
information science.
Dr. Leroy Hood (Genomics pioneer)

38. Wearable Health Devices
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS
Paramedics using the handheld
Stroke Angel system in the
field.
Ambulances equipped with PDA-
based checklists help guide
the paramedics’ examination of
patient status; the PDA transfers
examination results and patient
data wirelessly to an appropriate
hospital for pre-registration and
check-in.

39. Wearable Health Devices
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS
A belt that can
monitor a
developing baby's
heartbeat, sleep
and motion could
allow doctors to
monitor high-risk
pregnancies
without
hospitalising
mothers

40. Wearable Health Devices
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS
The ActiBelt system: Multiple
MS patients wore ActiBelts
for seven days at home so
that researchers could record
their movements and
measure their daily activity. It
can detect movements
related to running, walking,
sitting, standing up, lying
down.

41. 3D Printing
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS
In 2013, French Professor
Alain Carpentier
engineered the first self-
regulating artificial heart,
using biomaterials and
electronic sensors.
Electronic sensors and
microprocessors could
monitor blood pressure
and flow in real time –
instantly adjusting the
pulse rate.

42. Virtual & Augmented Reality
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS
https://youtu.be/zJiCt_VYxPY?list=UU8vwN4Sju7ER6KZzDADBK
BQ

43. Online Health Communities
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS

44. 31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS
Thank you!

45. 31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS
Turkey Case

46. Medical Informatics Education in Turkey
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS
•Computer education class first in 1984 in Medical faculties.
•Most of Medical Faculties have Computer class.
•Medical Informatician is
a Biostatician
a lecturer from Public Health department?
a lecturer from Medical Education department?
•Course Contents:
ICT (Information Communication Technology)
Computer Hardware - Office Programs
Medical Informatics
HIS, EHR, Health Standards, Databases, Medical Literature
and Internet, etc.
https://youtu.be/iTAKyezQggk

47. Medical Informatics SubFields
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS
•Health Information Systems
•Decision Support Systems
•Bioinformatics
Electronic Health Records
Image Processing
Signal Analysis
Nursing Information Systems
TeleMedicine
Health Standards(HL7 ,DICOM)
Augmented Reality
3-D Printing
Wearable Health devices
Medical Informatics Education

48. Decision Support Systems
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS
•Decision making process requires having all relevant
data displayed in a meaningful setting.
•Medical Images Analysis
 Abnormally detection from the medical images
 Image segmentation and registration

49. Bioinformatics
31.03.2015 Tbilisi State Medical University Aslı Yazağan
INTRODUCTION TO MEDICAL INFORMATICS
•Bioinformatic and biomedical researchers need resource-
intensive applications to store large data sets, catalogs and
archives.
•Image analysis, data mining, protein folding and gene
sequencing are all important tasks for biomedical researches