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                                         Management of Women with Adenocarcinoma in-situ (AIS)
                                            Diagnosed from a Diagnostic Excisional Procedure

                                        Hysterectomy - Preferred                                            Conservative Management
                                                                                                               Acceptable if future fertility desired




                                                                                            Margins Involved OR                                         Margins Negative
                                                                                               ECC Positive



                                                                        Re-excision                        Re-evaluation*                                     Long-term
                                                                                                            @ 6 mos - Acceptable                              Follow-up
                                                                       Recommended




* Using a combination of cytology, HPV testing, and colposcopy with endocervical sampling                Copyright 2006, 2007, American Society for Colposcopy and Cervical Pathology. All rights reserved.

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Adenocarcinoma in situ management

  • 1. 6 AIS Management of Women with Adenocarcinoma in-situ (AIS) Diagnosed from a Diagnostic Excisional Procedure Hysterectomy - Preferred Conservative Management Acceptable if future fertility desired Margins Involved OR Margins Negative ECC Positive Re-excision Re-evaluation* Long-term @ 6 mos - Acceptable Follow-up Recommended * Using a combination of cytology, HPV testing, and colposcopy with endocervical sampling Copyright 2006, 2007, American Society for Colposcopy and Cervical Pathology. All rights reserved.