This document discusses wounds, including their classification, stages of healing, types of healing, and factors that can affect the healing process. It also covers examining patients with wounds and potential complications. Wounds are breaks in the skin or mucous membranes and have signs like pain, bleeding, and an open defect. They can be classified based on their cause (surgical or accidental), type of injury (cut, puncture, etc.), and healing process (primary or secondary intention). The stages of wound healing are examination, inflammation, proliferation, and remodeling. Factors like nutrition, infection, ischemia, and medications can influence healing. Examining a wound includes assessing location, size, depth, underlying cause, and patient comorbidities
2. CONTENTS
• Introduction
• Classification of wounds
• Stages of wound healing
• Types of wound healing
• Factors affecting wound healing
• Examination of patient
• Treatment for wounds
• Complications of wounds
3. INTRODUCTION
Wound is the mechanical integrity of skin, mucosal membrane, more deep tissues
and organs. Wound is composed by wound cavity limited with walls and bottom of
wound and wound canal is deep and narrow.
Local signs of wound: pain, bleeding, open defect.
4. CLASSIFICATION
OF WOUNDS
A.Reason of wounding-
surgical is aseptic, accidental
wound is contaminated.
B.Type of injury and wound –
cut, punctured, contused,
bite, penetrated, lacerated.
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TYPES OF WOUND
HEALING PROCESS
• PRIMARY INTENTION - Clean
incised wounds in which the
edges of wounds are in close
apposition.
• SECONDARY INTENTION – When
the incision margins are not held
together and there is more than
10mm distance between them.
10. EXAMINATION OF PATIENT
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How was the wound created? If chronic, why is it still open?
What is the underlying etiology?
: Where on the body is it located? Is it in an area that is
difficult to offload or to keep clean? Is it in a region of high skin
tension? Is it near any vital structures such as a major artery?
: How long has this wound been present? (e.g., acute or
chronic)
• What: What anatomy does it involve (e.g., epidermis, dermis,
subcutaneous tissue, fascia, muscle, tendon, bone, arteries,
nerves)?
What comorbidities or social factors does the patient have
that might negatively impact their healing ability?Is it life-
threatening?
11.
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Local complications - delayed and
non-healing of the wound,
cellulitis, abscess formation,
osteomyelitis as well as further
wound breakdown.
Systemic complications -
bacteremia with the possibility of
distant hematogenous spread and
sepsis.
COMPLICATIONS OF WOUNDS
Acute wounds: an adequate angiogenesis promotes re-epithelialization, fibroblasts' proliferation, and neutrophils' anti-infection activities.
Chronic wounds : persistent local bacterial infections hinder the formation of novel blood vessels. In turn, the restricted angiogenesis hampers fibroblasts' proliferation and the neutrophils' anti-infection activities.
Haemostasis - A platelet plug prevents blood loss and a preliminary fibrin matrix is formed.
Inflammation then ensues to remove debris and prevent infection, commencing with neutrophil influx, which is promoted by histamine release from mast cells. Monocytes arrive later and differentiate into tissue macrophages to clear remaining cell debris and neutrophils.
During the proliferative phase, keratinocytes migrate to close the wound gap, blood vessels reform through angiogenesis, and fibroblasts replace the initial fibrin clot with granulation tissue. Macrophages and regulatory T cells are also vital for this stage of healing.
The deposited matrix is remodelled further by fibroblasts, blood vessels regress and myofibroblasts cause overall wound contraction.