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Day 12 October 16th CH 7+8 
Dr. Amy B Hollingsworth 
The University of Akron 
Fall 2014
7.11 Multi-gene Traits 
How are continuously varying traits 
such as height influenced by genes? 
Old wives’ tales suggest a couple of ways for predicting height: 
if the baby is a boy, they say to add five inches to the mothers’ 
height and average that with the father’s height. Or if it is a 
girl, subtract five inches from the father’s height and average 
that with the mother’s height. Alternatively, the lore says to 
just take the child’s height at two years and double it.
Additive Effects 
The Tall Gene – 
hormones and 
bone length 
and growth 
factors – oh 
what happens when the effects of alleles 
from multiple genes all contribute to the 
ultimate phenotype 
my!
Polygenic Trait 
 A trait that is influenced by many different 
genes 
Mind-blowingly 
complicated!!!
Why might computer nerds 
be more likely to have 
autistic children? 
•Autism involves 10 or 20 different genes! 
•Unusual abilities of perception, analytical 
skills, and focus. This idea—called the “geek 
theory of autism” 
•May be compounded by environmental 
effects
What is 
the 
benefit of 
“almost” 
having 
sickle cell 
disease?
7.12 Pleiotropy: How can one 
gene influence multiple traits?
The SRY Gene 
 “Sex-determining Region on the Y-chromosome” 
 Causes fetal gonads to develop as testes 
shortly after fertilization. 
 Following the gonads’ secretion of 
testosterone, other developmental changes 
also occur.
7.13 Why are more men 
than women color-blind? 
Sex-linked traits differ in their 
patterns of expression in males 
and females.
If a man is color-blind, did he 
inherit this condition from his 
mother, his father, or both 
parents?
men only get 
one chance to 
inherit the 
normal version 
of the gene
7.14 Environmental 
effects: Identical twins are 
not identical.
Drinking diet soda can be 
deadly if you carry a 
single bad gene. 
What gene is it and why is 
it so deadly?
Could you create a 
temporarily spotted Siamese 
cat with an ice pack? 
Why?
 Genotypes are not like blueprints that 
specify phenotypes. 
 Phenotypes are a product of the 
genotype in combination with the 
environment.
7.15 Most traits are passed on as 
independent features: Mendel’s law 
of independent assortment. 
Mendel didn’t know that genes were carried on chromosomes, so he believed that they 
were all just free-floating entities within cells. Given this perspective, it made sense to him 
that the inheritance pattern of one trait wouldn’t influence the inheritance of any other 
trait. He believed all genes behaved independently.
7.16 Red hair and freckles 
Genes on the same 
chromosome are sometimes 
inherited together.
Chapter 8: Evolution and Natural Selection 
Darwin’s dangerous idea: evolution by natural selection 
Lectures by Mark Manteuffel, St. Louis Community College ; Clicker Questions by Kristen Curran, University of Wisconsin-Whitewater
Evolution in Action 
8.1 We can see evolution occur 
right before us. Therefore, 
evolution is a scientific process.
Could you breed 
fruit flies who could 
live longer than 20 
hours on average?
Populations 
are studied
When these eggs hatch, do you think 
the flies in this new generation will 
live longer than 20 hours without 
food?
Make a prediction: A population of fruit flies was starved until 
80% of the flies were dead. The remaining flies were fed and 
offspring were produced. What do you expect to see in the next 
generation if you repeat the starvation experiment? 
1. More flies will be alive after 20 hours. 
2. Fewer flies will be alive after 20 hours. 
3. Fruit flies fed after 80% of the population is dead 
will lay more eggs. 
4. No change in the average number of fruit flies 
that were alive after 20 hours.
Make a prediction: A population of fruit flies was starved until 
80% of the flies were dead. The remaining flies were fed and 
offspring were produced. What do you expect to see in the next 
generation if you repeat the starvation experiment? 
1. More flies will be alive after 20 hours. 
2. Fewer flies will be alive after 20 hours. 
3. Fruit flies fed after 80% of the population is dead 
will lay more eggs. 
4. No change in the average number of fruit flies 
that were alive after 20 hours.
After 60 generations the average starvation 
resistance of fruit flies was 160 hours! What 
has happened to this population of fruit flies? 
1. They are genetically identical to 
the original population. 
2. The are genetically different from 
the original population.
After 60 generations the average starvation resistance 
of fruit flies was 160 hours! What has happened to 
this population of fruit flies? 
1. They are genetically identical to the 
original population. 
2. The are genetically different from the 
original population.
What happened? 
 Evolution 
• a genetic change in the population 
 Natural selection 
• the consequence of certain individual organisms in 
a population being born with characteristics that 
enable them to survive better and reproduce more 
than the offspring of other individuals in the 
population
Does evolution occur? 
 The answer is an unambiguous: YES. 
We can watch it happen in the lab 
whenever we want. 
Recall from our discussion of the scientific method 
that for an experiment’s results to be valid, they 
must be reproducible.
Experiments 
 Dogs? 
in Evolution 
 Rabbits?
In Nature -
Why are camels a successful species?
Evolution 
 How does evolution occur? 
 What types of changes can evolution 
cause in a population? 
 Five primary lines of evidence 
 Evolution by natural selection
Darwin’s Journey to an Idea 
8.2 Before Darwin, most people 
believed that all species had been 
created separately and were 
unchanging.
Button started the debate by suggesting the Earth 
had to be at least 75,000 years old!
Jean-Baptiste Lamarck 
 Biologist, early 1800s 
 Living species might change over time. 
(Was wrong about the mechanism - he thought that change came about 
through the use or disuse of features)
Charles Lyell 
 Geologist 
 1830 book Principles of Geology 
• Geological forces had shaped the earth and were 
continuing to do so. 
 Gradual but constant change 
This idea that the physical features of the earth were constantly changing would most 
closely parallel Darwin’s idea that the living species of the earth, too, were gradually— 
but constantly—changing.
We know the Earth is constantly 
changing 
• Fossils of shells have been found high in the 
Andes Mountains 
• Forest fires wipe out entire species of plants and 
animals. 
• Rivers flow, and carve out rock, creating two 
distinct shores, where different species live. 
• Lakes dry up, killing all marine life inside. 
• Pollution and Toxic spills kill organisms. 
• Volcanoes. 
• Humans are changing the earth.
In the 1790s, Georges Cuvier began to explore the bottoms 
of coal and slate mines and found fossils
Why were fossils such a problem for 
people at that time? 
• This was highly troubling for people at the 
time. 
http://www.bspcn.com/2009/04/03/11-extinct-animals-that-have-been-photographed-alive/
Extinction 
• five mass extinctions on earth, and four in the 
last 3.5 billion years - many species have 
disappeared in a relatively short period of 
geological time. 
• The "Great Dying" about 250 million years ago, 
which is estimated to have killed 90% of species 
existing at the time. 
• Most extinctions have occurred naturally, without 
human intervention: it is estimated that 99.9% of 
all species that have ever existed are now extinct.

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Day 12 october 16th ch 7+8

  • 1. Day 12 October 16th CH 7+8 Dr. Amy B Hollingsworth The University of Akron Fall 2014
  • 2. 7.11 Multi-gene Traits How are continuously varying traits such as height influenced by genes? Old wives’ tales suggest a couple of ways for predicting height: if the baby is a boy, they say to add five inches to the mothers’ height and average that with the father’s height. Or if it is a girl, subtract five inches from the father’s height and average that with the mother’s height. Alternatively, the lore says to just take the child’s height at two years and double it.
  • 3. Additive Effects The Tall Gene – hormones and bone length and growth factors – oh what happens when the effects of alleles from multiple genes all contribute to the ultimate phenotype my!
  • 4. Polygenic Trait  A trait that is influenced by many different genes Mind-blowingly complicated!!!
  • 5. Why might computer nerds be more likely to have autistic children? •Autism involves 10 or 20 different genes! •Unusual abilities of perception, analytical skills, and focus. This idea—called the “geek theory of autism” •May be compounded by environmental effects
  • 6. What is the benefit of “almost” having sickle cell disease?
  • 7. 7.12 Pleiotropy: How can one gene influence multiple traits?
  • 8. The SRY Gene  “Sex-determining Region on the Y-chromosome”  Causes fetal gonads to develop as testes shortly after fertilization.  Following the gonads’ secretion of testosterone, other developmental changes also occur.
  • 9. 7.13 Why are more men than women color-blind? Sex-linked traits differ in their patterns of expression in males and females.
  • 10.
  • 11. If a man is color-blind, did he inherit this condition from his mother, his father, or both parents?
  • 12. men only get one chance to inherit the normal version of the gene
  • 13. 7.14 Environmental effects: Identical twins are not identical.
  • 14.
  • 15. Drinking diet soda can be deadly if you carry a single bad gene. What gene is it and why is it so deadly?
  • 16. Could you create a temporarily spotted Siamese cat with an ice pack? Why?
  • 17.
  • 18.  Genotypes are not like blueprints that specify phenotypes.  Phenotypes are a product of the genotype in combination with the environment.
  • 19. 7.15 Most traits are passed on as independent features: Mendel’s law of independent assortment. Mendel didn’t know that genes were carried on chromosomes, so he believed that they were all just free-floating entities within cells. Given this perspective, it made sense to him that the inheritance pattern of one trait wouldn’t influence the inheritance of any other trait. He believed all genes behaved independently.
  • 20. 7.16 Red hair and freckles Genes on the same chromosome are sometimes inherited together.
  • 21.
  • 22. Chapter 8: Evolution and Natural Selection Darwin’s dangerous idea: evolution by natural selection Lectures by Mark Manteuffel, St. Louis Community College ; Clicker Questions by Kristen Curran, University of Wisconsin-Whitewater
  • 23.
  • 24. Evolution in Action 8.1 We can see evolution occur right before us. Therefore, evolution is a scientific process.
  • 25. Could you breed fruit flies who could live longer than 20 hours on average?
  • 27. When these eggs hatch, do you think the flies in this new generation will live longer than 20 hours without food?
  • 28. Make a prediction: A population of fruit flies was starved until 80% of the flies were dead. The remaining flies were fed and offspring were produced. What do you expect to see in the next generation if you repeat the starvation experiment? 1. More flies will be alive after 20 hours. 2. Fewer flies will be alive after 20 hours. 3. Fruit flies fed after 80% of the population is dead will lay more eggs. 4. No change in the average number of fruit flies that were alive after 20 hours.
  • 29. Make a prediction: A population of fruit flies was starved until 80% of the flies were dead. The remaining flies were fed and offspring were produced. What do you expect to see in the next generation if you repeat the starvation experiment? 1. More flies will be alive after 20 hours. 2. Fewer flies will be alive after 20 hours. 3. Fruit flies fed after 80% of the population is dead will lay more eggs. 4. No change in the average number of fruit flies that were alive after 20 hours.
  • 30.
  • 31. After 60 generations the average starvation resistance of fruit flies was 160 hours! What has happened to this population of fruit flies? 1. They are genetically identical to the original population. 2. The are genetically different from the original population.
  • 32. After 60 generations the average starvation resistance of fruit flies was 160 hours! What has happened to this population of fruit flies? 1. They are genetically identical to the original population. 2. The are genetically different from the original population.
  • 33. What happened?  Evolution • a genetic change in the population  Natural selection • the consequence of certain individual organisms in a population being born with characteristics that enable them to survive better and reproduce more than the offspring of other individuals in the population
  • 34. Does evolution occur?  The answer is an unambiguous: YES. We can watch it happen in the lab whenever we want. Recall from our discussion of the scientific method that for an experiment’s results to be valid, they must be reproducible.
  • 35. Experiments  Dogs? in Evolution  Rabbits?
  • 37. Why are camels a successful species?
  • 38. Evolution  How does evolution occur?  What types of changes can evolution cause in a population?  Five primary lines of evidence  Evolution by natural selection
  • 39.
  • 40. Darwin’s Journey to an Idea 8.2 Before Darwin, most people believed that all species had been created separately and were unchanging.
  • 41. Button started the debate by suggesting the Earth had to be at least 75,000 years old!
  • 42. Jean-Baptiste Lamarck  Biologist, early 1800s  Living species might change over time. (Was wrong about the mechanism - he thought that change came about through the use or disuse of features)
  • 43. Charles Lyell  Geologist  1830 book Principles of Geology • Geological forces had shaped the earth and were continuing to do so.  Gradual but constant change This idea that the physical features of the earth were constantly changing would most closely parallel Darwin’s idea that the living species of the earth, too, were gradually— but constantly—changing.
  • 44. We know the Earth is constantly changing • Fossils of shells have been found high in the Andes Mountains • Forest fires wipe out entire species of plants and animals. • Rivers flow, and carve out rock, creating two distinct shores, where different species live. • Lakes dry up, killing all marine life inside. • Pollution and Toxic spills kill organisms. • Volcanoes. • Humans are changing the earth.
  • 45. In the 1790s, Georges Cuvier began to explore the bottoms of coal and slate mines and found fossils
  • 46. Why were fossils such a problem for people at that time? • This was highly troubling for people at the time. http://www.bspcn.com/2009/04/03/11-extinct-animals-that-have-been-photographed-alive/
  • 47. Extinction • five mass extinctions on earth, and four in the last 3.5 billion years - many species have disappeared in a relatively short period of geological time. • The "Great Dying" about 250 million years ago, which is estimated to have killed 90% of species existing at the time. • Most extinctions have occurred naturally, without human intervention: it is estimated that 99.9% of all species that have ever existed are now extinct.