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[object Object],[object Object]
Introduction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Why purify the water? ,[object Object],[object Object],[object Object]
Contaminants of water ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Contaminants of water (2) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
  Water requirement and use ,[object Object],[object Object],[object Object],[object Object],[object Object]
Water requirement and use ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Water requirements and use ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Water quality specifications ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Drinking water / potable water ,[object Object],[object Object],[object Object],[object Object],[object Object]
Purified water Spec as per IP Conform to the test Chloride NMT 0.1 ppm Heavy Metals (2.4.8) Conform to the test 0.5ml of 0.01M EDTA Ca and  Mg NMT 0.2 ppm Ammonium NMT 5.1  µS/cm  (EP) Conductivity ( at 25° C ) NMT 0.2 ppm Nitrates Conform to the test Acidity or Alkalinity Clear, Colourless, Odourless and tasteless Nature Limit Parameter
Purified water Spec as per IP Conform to the test Oxid. Substances < 0.25 EU/ml Endotoxins (2.6.14) NMT 80 cfu/ml (alert limit) NMT 100 cfu/ml Bioburden (2.6.12) NMT 10ppb Aluminium NMT 0.001% Res. on Evaporation Conform to the test Sulphates Limit Parameter
Purified Water (PW) ,[object Object],[object Object],[object Object],[object Object]
Quality of water  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Purified water Spec USP/EP Conform to the test Oxid. Substances Conform to the test Acidity or Alkalinity NMT 0.1 ppm Heavy Metals (2.4.8) Conform to the test NO2 NMT 0.2 ppm NO3 < 0.5 ppm TOC NMT 2.1  µS/cm  (USP) NMT 5.1  µS/cm  (EP) Conductivity ( at 25° C ) 5 - 7 pH Clear, Colourless, Odourless Nature Limit Parameter
Purified water Spec USP/EP < 0.5 ppm TOC < 0.25 EU/ml Endotoxins (2.6.14) NMT 80 cfu/ml (alert limit) NMT 100 cfu/ml Bioburden (2.6.12) NMT 0.001% Res. on Evaporation Conform to the test Ca / Mg NMT 0.2 ppm Ammonium Conform to the test Sulphate Conform to the test Chloride Limit Parameter
Water purification methods ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Water system requirements ,[object Object],[object Object],[object Object],[object Object]
Water system requirements ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Typical water storage and distribution schematic Water must be kept circulating Spray ball Cartridge filter 1 µm Air break to drain Outlets Hygienic pump Optional in-line filter 0,2 µm UV light Feed Water from DI or RO Heat Exchanger Ozone Generator Hydrophobic air filter & burst disc
Sampling of purified water ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
USP tests ,[object Object],[object Object],[object Object]
<645> Water Conductivity  ,[object Object],[object Object],[object Object],[object Object],[object Object],1.9 50 1.3 25 1.5 35 1.1 20 1.4 30 1.0 15 Conductivity  Requirement (µS/cm) Temp (°C) Conductivity  Requirement  (µS/cm) Temp (°C)
<645> Water Conductivity  ,[object Object],[object Object],[object Object],[object Object],[object Object]
<645> Water Conductivity  ,[object Object],[object Object],[object Object],[object Object],[object Object]
<645> Water Conductivity  2.8 5.5 2.4 6.0 2.2 6.5 2.1 6.6 3.1 6.8 4.6 7.0 4.7 5.0 Conductivity Requirement (µS/cm) pH
Water system Validation ,[object Object],[object Object],[object Object]
Phase- I; Validation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Phase- I; Validation ,[object Object],[object Object],[object Object],[object Object]
Phase- II; Validation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Phase- III; Validation ,[object Object],[object Object]
Control and monitoring ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Water for ap is amsavel

  • 1.
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11. Purified water Spec as per IP Conform to the test Chloride NMT 0.1 ppm Heavy Metals (2.4.8) Conform to the test 0.5ml of 0.01M EDTA Ca and Mg NMT 0.2 ppm Ammonium NMT 5.1 µS/cm (EP) Conductivity ( at 25° C ) NMT 0.2 ppm Nitrates Conform to the test Acidity or Alkalinity Clear, Colourless, Odourless and tasteless Nature Limit Parameter
  • 12. Purified water Spec as per IP Conform to the test Oxid. Substances < 0.25 EU/ml Endotoxins (2.6.14) NMT 80 cfu/ml (alert limit) NMT 100 cfu/ml Bioburden (2.6.12) NMT 10ppb Aluminium NMT 0.001% Res. on Evaporation Conform to the test Sulphates Limit Parameter
  • 13.
  • 14.
  • 15. Purified water Spec USP/EP Conform to the test Oxid. Substances Conform to the test Acidity or Alkalinity NMT 0.1 ppm Heavy Metals (2.4.8) Conform to the test NO2 NMT 0.2 ppm NO3 < 0.5 ppm TOC NMT 2.1 µS/cm (USP) NMT 5.1 µS/cm (EP) Conductivity ( at 25° C ) 5 - 7 pH Clear, Colourless, Odourless Nature Limit Parameter
  • 16. Purified water Spec USP/EP < 0.5 ppm TOC < 0.25 EU/ml Endotoxins (2.6.14) NMT 80 cfu/ml (alert limit) NMT 100 cfu/ml Bioburden (2.6.12) NMT 0.001% Res. on Evaporation Conform to the test Ca / Mg NMT 0.2 ppm Ammonium Conform to the test Sulphate Conform to the test Chloride Limit Parameter
  • 17.
  • 18.
  • 19.
  • 20. Typical water storage and distribution schematic Water must be kept circulating Spray ball Cartridge filter 1 µm Air break to drain Outlets Hygienic pump Optional in-line filter 0,2 µm UV light Feed Water from DI or RO Heat Exchanger Ozone Generator Hydrophobic air filter & burst disc
  • 21.
  • 22.
  • 23.
  • 24.
  • 25.
  • 26. <645> Water Conductivity 2.8 5.5 2.4 6.0 2.2 6.5 2.1 6.6 3.1 6.8 4.6 7.0 4.7 5.0 Conductivity Requirement (µS/cm) pH
  • 27.
  • 28.
  • 29.
  • 30.
  • 31.
  • 32.