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Myeloproliferative  Neoplasms (MPN) Ahmed Elshebiny, MD University of Menoufyia
Case ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Case cont. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Hematological malignancies ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Malignant cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Hematology lectures Myeloproliferative neoplasms
Myeloproliferative neoplasms (MPN) ,[object Object],[object Object]
Epidemiology ,[object Object],[object Object]
Etiology ,[object Object],[object Object]
Genetic abnormalities ,[object Object],[object Object],[object Object],[object Object]
 
Symptoms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ET
Myelofibrosis showing Leukoerythroblastic reaction
CML
Hyperviscosity syndrome ,[object Object],[object Object],[object Object],[object Object],[object Object]
Polythycemia Vera Myeloproliferative neoplasms
Polythycemia vera( bone marrow)
Pathophysiology ,[object Object],[object Object]
Pathophysiology cont. ,[object Object],[object Object],[object Object]
JAK  2 mutation
Clinical suspicion ,[object Object]
Manifestations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Course ,[object Object],[object Object],[object Object],[object Object],[object Object]
DD ,[object Object],[object Object],[object Object]
Acquired Secondary polythycemia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Essential thrombocythemia (ET) Myeloproliferative neoplasms
Essential Thrombocythemia ,[object Object],[object Object],[object Object]
Diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object]
Reactive thrombocythemia ,[object Object],[object Object],[object Object]
Primary Myelofibrosis Myeloproliferative neoplasms
Myelofibrosis ,[object Object],[object Object],[object Object],[object Object]
Myelofibrosis
Myelofibrosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Lab finding in myelofibrosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment Myeloproliferative neoplasms
TTT of Polycythemia Vera ,[object Object],[object Object],[object Object]
Hydroxyurea ,[object Object],[object Object],[object Object],[object Object]
Treatment of ET ,[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment of myelofibrosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment of CML ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
References ,[object Object],[object Object],[object Object],[object Object]
THANK  YOU

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