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Anatomy of the Eye

         Dr. Alexander D. Tan
 UP-PGH Department of Ophthalmology
         and Visual Sciences
Objectives

Describe the different anatomic parts of the human
eye
  Bony Orbit
  Eyelids and Lacrimal Drainage System
  Extraocular Muscles
  Cornea and Conjunctivae
  Uvea, Choroid and Sclerae
  Retina
Bony Orbit
Human Orbit

Pear shaped ; Volume: 30 cc
Orbital entrance is 35mm in height and 45mm width
Maximum width is 1 cm behind the orbital margin
Depth 40 to 45mm, medial walls are parallel, lateral
walls are 90 degrees apart
Bones: Frontal, Zygomatic, Maxillary
Bone, Ethmoid, Sphenoid, Lacrimal and Palatine
Bones of the Orbit
Roof: Frontal bone and lesser wing of the Sphenoid
bone
Medial Wall: Frontal Process of Maxillary
Bone, Lacrimal Bone, Ethmoid Bone and lesser wing
of Sphenoid
Orbital Floor: Maxilla, Palatine, orbital plate of the
Zygomatic Bone
Lateral Wall: Zygomatic and greater wing of the
Sphenoid Bone
Foramina, Ducts, Canals and Fissures

    Optic Foramen (lesser wing of Sphenoid): optic
    nerve, ophthalmic artery and sympathetic fibers
    from carotid plexus
    Supraorbital foramen: blood vessels and
    supraorbital nerve (branch of CN V1)
    Anterior Ethmoidal Foramen, Posterior Ethmoidal
    Foramen and Zygomatic Foramen
    Nasolacrimal Duct
    Infraorbital Canal: infraorbital nerve (V2)
Foramina, Ducts, Canals and Fissures

    SOF: lacrimal nerve of V1, frontal nerve of V1, CN
    IV, SOV; suprior and inf divisions of CN III, nasociliary
    branch of V1, sympathetic roots of ciliary ganglion
    and CN VI, inferior ophthalmic vein
    IOF: infraorbital and zygmatic branches of
    V2, orbital nerve from pterygopalatine ganglion and
    inferior ophthalmic vein
Eyelids and Lacrimal Drainage
Lacrimal Drainage System
Extraocular Muscles
Extraocular Muscles
7 EOMs: Medial Rectus, Lateral Rectus, Superior
Rectus, Inferior Rectus, Superior Oblique, Inferior
Oblique and Levator Palpebrae Superioris
Inserts anteriorly at the Globe: MR, IR, LR, SR (spiral
of Tillaux)
SO: passing through the trochlea to sclera under SR
IO: inserts postero-infero-temporal quadrant
Annulus of Zinn: 4 Recti muscles; above is Levator
SO: sphenoid bone, IO maxillary bone
Innervation of EOMs


Lateral Rectus: CN VI
Superior Oblique: CN IV
Rest: CN III
Conjunctivae

3 Geographic Zones: Palpebral, Forniceal and
Bulbar
Mucous membrane : non keratinizing squamous
epithelium with numerous goblet cells and a thin
richly vascularized substantia propria containing
lymphatic vessels, plasma cells, macrophages and
mast cells.
Eyelids and Lacrimal Drainage
Globe
Not a true sphere: ROC Cornea: 8mm ROC Sclera:
12mm forming an oblate spheroid
Axial length is 23 to 25 mm; transverse distance is 24
mm; total volume os 6.5 to 7 ml
Three Cavities
  Anterior Chamber: 3 mm deep; 200 ul
  Posterior Chamber 60 ul
  Vitreous Cavity (2/3 of the volume of the eye) 5 to 6 ml
Eyeball is Cornea anteriorly and Sclera posteriorly
Sclera / Uvea

SCLERA : Opaque and white
  Thinnest just behind the insertion of the rectus
  muscles ; 1 mm posteriorly, and ; sieve-like at
  lamina cribrosa
  Generally avascular
  Lamina fusca
UVEA: choroid, ciliary body, iris
  Highly vascular, nutritive and supportive
RETINA: innermost layer
Cornea
Main refractive element of the eye 43 diopters
12 mm horizontal ; 11 mm vertical
1mm thick at the periphery, 0.5 mm thick at the
center
Central 1/3 is nearly spherical (4mm)
Posterior cornea more curved than the anterior
EPITHELIUM: Nonkeratinized, stratified, squamous
epithelium ; 2 to 3 layers of polygonal “wing” cells;
basal cell layer
BOWMANS LAYER: tough layer , does not regenerate
Cornea
STROMA: 90% of total thickness; composed of
collagen producing keratocytes, ground
substance, and collagen lamellae; regularity of fibers
maintain transparency
DESCEMET’S MEMBRANE: basal lamina of the corneal
endothelium
  Increases thickness with age
  Peripheral excresences (Hassal Henle warts)
  Central excresences (corneal gutata)
CORNEA
ENDOTHELIUM: single layer of hexagonal
cells, 500,000 cells (3,000 cells/mm2)
Maintains corneal transparency and deturgescence
Mitosis is rare, number decreases with age
UVEAL TRACT
Main vascular compartment of the eye
Three attachments to the sclera : scleral spur, exit
points of vortex veins and optic nerve
IRIS: determines the size of the pupil, eye
color, sphincter muscle and dilator muscle
CILIARY BODY: formation of the aqueous humor, lens
accomodation, trabecular and uveoscleral outflow of
aqueous humor
  Pars plana: 4 mm from limbus ; Pars plicata 70 radial
  ciliary processes
  Non pigmented epithelium: aqueous formation
  Ciliary muscle: longitudinal, radial and circular
UVEAL TRACT

CHOROID: nourishes the outer portion of the retina
  Three layers: choriocapillaries, middler layer of small
  vessels, outer layer of large vessels
  Long and short posterior ciliary arteries; anterior ciliary
  arteries
  BRUCHS MEMBRANE: fusion of the basal lamina of RPE
  and choriorcapillaries of the choroid
Crystalline Lens
Avascular, 4mm thick and 9 mm in diameter
Lens Capsule, outer cortex and inner nucleus.
Held in place by zonular fibers
Secondary refractive element of the eye
Turns into a cataract
Retina
Thin, semi-transparent, multilayered sheet
Receptor and Processor of images
Anterior margin: ora serrata , strongly attached at the ora
serrata and optic disc
0.1 mm thick at the ora serrata and 0.56mm thick at the
posterior pole
MACULA: center of the posterior pole
  3 mm of yellowish pigmentation
  FOVEA : center of the macula; depression seen producing a
  FOVEAL REFLEX
  FOVEOLA: most center portion of FOVEA : all photoreceptors
  are cones, thinnest part of the retina
Retina
Composed of RETINAL PIGMENT EPITHELIUM
AND SENSORY RETINA
RPE: single layer of hexagonal cells, functions to
trap light
Photoreceptors: Rods for dark vision and Cones
for light and color vision
Modulator Cells: Bipolar, Amacrine and
Horizontal cells
Transmitter Cells: Ganglion Cell
10 Layers of the Retina
1.    Internal limiting membrane
2.    Nerve fiber layer
3.    Ganglion cell layer
4.    Inner plexiform layer
5.    Inner nuclear layer
6.    Outer plexiform layer
7.    Outer nuclear layer
8.    External limiting membrane
9.    Photoreceptor layer
10.   Retinal Pigment Epithelium
Retina / Vitreous
Blood supply
  Choriocapillaries: outer third of the retina
  Central retinal artery: inner 2/3 of the retina
VITREOUS:
  2/3 volume and weight of the eye
  99% water plus collagen and hyaluronic acid

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Anatomy for lu4

  • 1. Anatomy of the Eye Dr. Alexander D. Tan UP-PGH Department of Ophthalmology and Visual Sciences
  • 2. Objectives Describe the different anatomic parts of the human eye Bony Orbit Eyelids and Lacrimal Drainage System Extraocular Muscles Cornea and Conjunctivae Uvea, Choroid and Sclerae Retina
  • 4. Human Orbit Pear shaped ; Volume: 30 cc Orbital entrance is 35mm in height and 45mm width Maximum width is 1 cm behind the orbital margin Depth 40 to 45mm, medial walls are parallel, lateral walls are 90 degrees apart Bones: Frontal, Zygomatic, Maxillary Bone, Ethmoid, Sphenoid, Lacrimal and Palatine
  • 5. Bones of the Orbit Roof: Frontal bone and lesser wing of the Sphenoid bone Medial Wall: Frontal Process of Maxillary Bone, Lacrimal Bone, Ethmoid Bone and lesser wing of Sphenoid Orbital Floor: Maxilla, Palatine, orbital plate of the Zygomatic Bone Lateral Wall: Zygomatic and greater wing of the Sphenoid Bone
  • 6. Foramina, Ducts, Canals and Fissures Optic Foramen (lesser wing of Sphenoid): optic nerve, ophthalmic artery and sympathetic fibers from carotid plexus Supraorbital foramen: blood vessels and supraorbital nerve (branch of CN V1) Anterior Ethmoidal Foramen, Posterior Ethmoidal Foramen and Zygomatic Foramen Nasolacrimal Duct Infraorbital Canal: infraorbital nerve (V2)
  • 7. Foramina, Ducts, Canals and Fissures SOF: lacrimal nerve of V1, frontal nerve of V1, CN IV, SOV; suprior and inf divisions of CN III, nasociliary branch of V1, sympathetic roots of ciliary ganglion and CN VI, inferior ophthalmic vein IOF: infraorbital and zygmatic branches of V2, orbital nerve from pterygopalatine ganglion and inferior ophthalmic vein
  • 8.
  • 12. Extraocular Muscles 7 EOMs: Medial Rectus, Lateral Rectus, Superior Rectus, Inferior Rectus, Superior Oblique, Inferior Oblique and Levator Palpebrae Superioris Inserts anteriorly at the Globe: MR, IR, LR, SR (spiral of Tillaux) SO: passing through the trochlea to sclera under SR IO: inserts postero-infero-temporal quadrant Annulus of Zinn: 4 Recti muscles; above is Levator SO: sphenoid bone, IO maxillary bone
  • 13. Innervation of EOMs Lateral Rectus: CN VI Superior Oblique: CN IV Rest: CN III
  • 14.
  • 15. Conjunctivae 3 Geographic Zones: Palpebral, Forniceal and Bulbar Mucous membrane : non keratinizing squamous epithelium with numerous goblet cells and a thin richly vascularized substantia propria containing lymphatic vessels, plasma cells, macrophages and mast cells.
  • 17. Globe Not a true sphere: ROC Cornea: 8mm ROC Sclera: 12mm forming an oblate spheroid Axial length is 23 to 25 mm; transverse distance is 24 mm; total volume os 6.5 to 7 ml Three Cavities Anterior Chamber: 3 mm deep; 200 ul Posterior Chamber 60 ul Vitreous Cavity (2/3 of the volume of the eye) 5 to 6 ml Eyeball is Cornea anteriorly and Sclera posteriorly
  • 18.
  • 19. Sclera / Uvea SCLERA : Opaque and white Thinnest just behind the insertion of the rectus muscles ; 1 mm posteriorly, and ; sieve-like at lamina cribrosa Generally avascular Lamina fusca UVEA: choroid, ciliary body, iris Highly vascular, nutritive and supportive RETINA: innermost layer
  • 20. Cornea Main refractive element of the eye 43 diopters 12 mm horizontal ; 11 mm vertical 1mm thick at the periphery, 0.5 mm thick at the center Central 1/3 is nearly spherical (4mm) Posterior cornea more curved than the anterior EPITHELIUM: Nonkeratinized, stratified, squamous epithelium ; 2 to 3 layers of polygonal “wing” cells; basal cell layer BOWMANS LAYER: tough layer , does not regenerate
  • 21. Cornea STROMA: 90% of total thickness; composed of collagen producing keratocytes, ground substance, and collagen lamellae; regularity of fibers maintain transparency DESCEMET’S MEMBRANE: basal lamina of the corneal endothelium Increases thickness with age Peripheral excresences (Hassal Henle warts) Central excresences (corneal gutata)
  • 22. CORNEA ENDOTHELIUM: single layer of hexagonal cells, 500,000 cells (3,000 cells/mm2) Maintains corneal transparency and deturgescence Mitosis is rare, number decreases with age
  • 23.
  • 24. UVEAL TRACT Main vascular compartment of the eye Three attachments to the sclera : scleral spur, exit points of vortex veins and optic nerve IRIS: determines the size of the pupil, eye color, sphincter muscle and dilator muscle CILIARY BODY: formation of the aqueous humor, lens accomodation, trabecular and uveoscleral outflow of aqueous humor Pars plana: 4 mm from limbus ; Pars plicata 70 radial ciliary processes Non pigmented epithelium: aqueous formation Ciliary muscle: longitudinal, radial and circular
  • 25. UVEAL TRACT CHOROID: nourishes the outer portion of the retina Three layers: choriocapillaries, middler layer of small vessels, outer layer of large vessels Long and short posterior ciliary arteries; anterior ciliary arteries BRUCHS MEMBRANE: fusion of the basal lamina of RPE and choriorcapillaries of the choroid
  • 26. Crystalline Lens Avascular, 4mm thick and 9 mm in diameter Lens Capsule, outer cortex and inner nucleus. Held in place by zonular fibers Secondary refractive element of the eye Turns into a cataract
  • 27.
  • 28. Retina Thin, semi-transparent, multilayered sheet Receptor and Processor of images Anterior margin: ora serrata , strongly attached at the ora serrata and optic disc 0.1 mm thick at the ora serrata and 0.56mm thick at the posterior pole MACULA: center of the posterior pole 3 mm of yellowish pigmentation FOVEA : center of the macula; depression seen producing a FOVEAL REFLEX FOVEOLA: most center portion of FOVEA : all photoreceptors are cones, thinnest part of the retina
  • 29. Retina Composed of RETINAL PIGMENT EPITHELIUM AND SENSORY RETINA RPE: single layer of hexagonal cells, functions to trap light Photoreceptors: Rods for dark vision and Cones for light and color vision Modulator Cells: Bipolar, Amacrine and Horizontal cells Transmitter Cells: Ganglion Cell
  • 30. 10 Layers of the Retina 1. Internal limiting membrane 2. Nerve fiber layer 3. Ganglion cell layer 4. Inner plexiform layer 5. Inner nuclear layer 6. Outer plexiform layer 7. Outer nuclear layer 8. External limiting membrane 9. Photoreceptor layer 10. Retinal Pigment Epithelium
  • 31. Retina / Vitreous Blood supply Choriocapillaries: outer third of the retina Central retinal artery: inner 2/3 of the retina VITREOUS: 2/3 volume and weight of the eye 99% water plus collagen and hyaluronic acid

Notas do Editor

  1. The bony orbit provides a container of the globe and gives protection to its contents.
  2. Fixed volume means, when there is a tumor or swelling … the eyeball is pushed forward resulting in proptosis and when one of the orbital walls are damaged such as in orbital fractures, this results in increase in its relative volume resulting in posterior displacement of the globe or enophthalmos
  3. Supraorbital foramen is located at the medial third of the superior margin of the orbit.
  4. Supraorbital foramen is located at the medial third of the superior margin of the orbit.
  5. Main function of the eyelid is for protection, contains oil gland (Meibomian glands) which form the outermost layer of the tear film, contains the tear drainage, cosmesisMuscles that open the eye are : levatorpalpebraesuperioris, mullers muscle, frontalis muscle ; close the eye: orbicularis ; corrugator supercilii ; procerus muscle
  6. The amount of tears present in our eye is determined by tear production, evaporation, and drainage. The lacrimal drainage system is composed of the punctum, canaliculus and nasolacrimal duct.
  7. Palpebral begins at the mucocutaneous junction of the eyelid and covers the inner eyelid surface; adheres firmly to the tarsusFornix: tissues are redundant and freely movableBulbar Conjunctiva is movable but fuses with the Tenons capsule and inserts into the limbus
  8. Greater variation in fibril separation and diameterGreater degree of fibril interweave
  9. Stem cells in the limbus
  10. Zonular fibers attah primarily in the valleys of the ciliary processes but also along the pars plana
  11. Retina occupies the inner aspect of the posterior 2/3s of the human eye.
  12. The sensory retina is made of layers of cells composed of receptor neurons and glial cells to receive, modulate and transmit images to the brain.Light received by photoreceptors are then processed by modulator cellsTransmitter cells: Transmit the visual impulses from bipolar and amacrine cells to the midbrain
  13. Outer plexiform to the RPE