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1
ANGEL DAS
DM WIMS
LARYNGEAL CARCINOMA
 Ca affecting larynx
 3 sub types
-supra glottic
-glottic
-Sub glottic
RISK FACTORS
 More common in males
 Tobacco smoking
 alcohol
 Hpv infection in the throat
 Previous radiation to neck
 occupational to exposure to asbestos
CLINICAL MANIFESTATION
 Depends on the location of tumour
 Supraglottic
early features - throat pain
dysphagia
referred pain in the ear
lymph node enlargement
 late symptoms
hoarseness
weight loss
halitosis
GLOTTIC CANCER
 SYMPTOMS
hoarseness of voice – early symptom
stridor and laryngeal obstruction -
due to cord fixation
SUBGLOTTIC CANCER
 Earliest features –stridor and laryngeal
obstruction
 Late feature-hoarseness
TNM Staging
M0 – no metatasis
M1 - metastasis
DIAGNOSIS
 History
 Physical examination
- extralaryngeal spread of
tumor
- Nodal metastasis
 Indirect laryngoscopy
- appearance of lesion
- vocal cord mobility
- extent of disease
 Direct laryngoscopy
- hidden areas of larynx
-extent of disease
Radiography
-X ray chest
-Soft tissue lateral view
of neck
-CT & MRI
TREATMENT
Glottic Carcinoma
 T1- Radiotherapy
 T2- Vertical Hemilaryngectomy
 T3 &T4 – Total laryngectomy with neck
node dissection
Subglottic Carcinoma
 T1 & T2- Radiotherapy
 T3 & T4- Total laryngectomy with post-op
radiation
Supraglottic Carcinoma
 T1- Radiation & CO2 laser
 T2- Supraglottic laryngectomy
 T3 & T4- Total laryngectomy & post op
radiation
VOICE REHABILITATION
 Esophageal speech
 Tracheo-esophageal speech
 Electrolarynx
15
Esophageal speech
16
Tracheo-esophageal Speech
17
Electrolarynx
18
19

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Larynx