5. Neurona sin estimulación Chapter 33 (Líquido extracelular) (Citoplasma Neuronal, cargado negativamente) (Membrana Neuronal) Org - Na + Org - Org - Org - Org - K + K + K + K + K + Cl - Cl - Cl - Cl - Na + Na + Na + Canal Potasio Canal Sodio (cerrado)
6. Iniciación Potential de Accion Chapter 33 Org - K + K + K + Cl - Na + Na + K + Na + Na + Na + (Líquido Extracelular) (Citoplasma Neuronal, cargado positivamente) (cargado negativamente) Org - Na + Org - Org - K + K + Cl - Na + K + K + K + K + Na + Na + Cl -
9. Estructura y Operacion de la Sinápsis Chapter 33 1 Iniciación de un potencial de acción 2 Potencial de Acción llega al terminal sináptico de la neurona presináptica 3 Vesicula Sináptica libera neurotransmisor 4 Receptor se une al neurotransmisor y abre canal iónico
Biology: Life on Earth (Audesirk) Chapter 33 The ionic composition of a neuron’s cytoplasm is significantly different from that of the extracellular fluid. The neuron maintains high concentrations of K+ and large organic ions (Org– ); the extracellular fluid is high in Na+ and Cl– .
Biology: Life on Earth (Audesirk) Chapter 33 An unstimulated neuron
Biology: Life on Earth (Audesirk) Chapter 33 Initiation of an action potential
Biology: Life on Earth (Audesirk) Chapter 33 Initiation of an action potential
Biology: Life on Earth (Audesirk) Chapter 33 Propagation of an action potential
Biology: Life on Earth (Audesirk) Chapter 33 The synaptic terminal contains numerous vesicles that enclose a neurotransmitter for which the postsynaptic neuron has membrane receptors. When an action potential enters the synaptic terminal of the presynaptic neuron, the vesicles dump their neurotransmitter into the gap between the neurons. The neurotransmitter diffuses rapidly across the space, binds to postsynaptic receptors, and causes ion channels to open. Ions flow through these open channels, causing a postsynaptic potential in the postsynaptic cell.
Biology: Life on Earth (Audesirk) Chapter 33 A recording (by oscilloscope) of the electrical events in a nerve cell. The resting potential is about 60 millivolts negative with respect to the outside. 1) When a PSP stimulates the cell to threshold, membrane channels permeable to sodium open and sodium enters the cell, powered by diffusion and by electrical attraction; 2) the inside of the cell becomes positively charged. 3) Shortly thereafter, other membrane channels permeable to potassium open and potassium leaves, driven by diffusion and electrical repulsion from the now-positive inside of the cell, until the resting potential is reestablished.